scholarly journals Pesticide Aptasensors—State of the Art and Perspectives

Sensors ◽  
2020 ◽  
Vol 20 (23) ◽  
pp. 6809
Author(s):  
Kamonrat Phopin ◽  
Tanawut Tantimongcolwat
Keyword(s):  
Mass Spectrometry ◽  
Development Process ◽  
State Of The Art ◽  
Cost Effective ◽  
Pesticide Analysis ◽  
Future Outlook ◽  
Advantages And Disadvantages ◽  
Resource Requirements ◽  
Recognition Elements ◽  
User Friendly

Contamination by pesticides in the food chain and the environment is a worldwide problem that needs to be actively monitored to ensure safety. Unfortunately, standard pesticide analysis based on mass spectrometry takes a lot of time, money and effort. Thus, simple, reliable, cost-effective and field applicable methods for pesticide detection have been actively developed. One of the most promising technologies is an aptamer-based biosensor or so-called aptasensor. It utilizes aptamers, short single-stranded DNAs or RNAs, as pesticide recognition elements to integrate with various innovative biosensing technologies for specific and sensitive detection of pesticide residues. Several platforms for aptasensors have been dynamically established, such as colorimetry, fluorometry, electrochemistry, electrochemiluminescence (ECL) and so forth. Each platform has both advantages and disadvantages depending on the purpose of use and readiness of technology. For example, colorimetric-based aptasensors are more affordable than others because of the simplicity of fabrication and resource requirements. Electrochemical-based aptasensors have mainly shown better sensitivity than others with exceedingly low detection limits. This paper critically reviews the progression of pesticide aptasensors throughout the development process, including the selection, characterization and modification of aptamers, the conceptual frameworks of integrating aptamers and biosensors, the ASSURED (affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free and deliverable to end users) criteria of different platforms and the future outlook.

The Technique of Raman Spectroscopy: A State-of-the-Art Comparison to Infrared

1971 ◽  
Vol 25 (4) ◽  
pp. 430-439 ◽  
Author(s):  
Howard J. Sloane
Keyword(s):  
Raman Spectroscopy ◽  
State Of The Art ◽  
The State ◽  
Point Of View ◽  
Complementary Information ◽  
Future Outlook ◽  
Sample Handling ◽  
Advantages And Disadvantages ◽  
Sampling Procedures ◽  
Made In

This paper in a tabulated summary format discusses the state-of-the-art of Raman spectroscopy for commercially available instrumentation. A comparison to infrared is made in terms of (I) instrumentation, (II) sample handling, and (III) applications. Although the two techniques yield similar and often complementary information, they are quite different from the point of view of instrumentation and sampling procedures. This leads to various advantages and disadvantages or limitations for each. These are discussed as well as the future outlook.

scholarly journals Methodology for Measuring Greenhouse Gas Emissions from Agricultural Soils Using Non-isotopic Techniques

2021 ◽  
pp. 11-108
Author(s):  
M. Zaman ◽  
K. Kleineidam ◽  
L. Bakken ◽  
J. Berendt ◽  
C. Bracken ◽  
...  
Keyword(s):  
Agricultural Soils ◽  
Cost Effective ◽  
Emission Measurement ◽  
Closed Chamber ◽  
Advantages And Disadvantages ◽  
Flux Measurements ◽  
Cost Effective Alternative ◽  
User Friendly ◽  
Closed Chambers

AbstractSeveral approaches exist for measuring greenhouse gases (GHGs), mainly CO2, N2O, and CH4, from soil surfaces. The principle methods that are used to measure GHG from agricultural sites are chamber-based techniques. Both open and closed chamber techniques are in use; however, the majority of field applications use closed chambers. The advantages and disadvantages of different chamber techniques and the principal steps of operation are described. An important part of determining the quality of the flux measurements is the storage and the transportation of the gas samples from the field to the laboratory where the analyses are carried out. Traditionally, analyses of GHGs are carried out via gas chromatographs (GCs). In recent years, optical analysers are becoming increasingly available; these are user-friendly machines and they provide a cost-effective alternative to GCs. Another technique which is still under development, but provides a potentially superior method, is Raman spectroscopy. Not only the GHGs, but also N2, can potentially be analysed if the precision of these techniques is increased in future development. An important part of this chapter deals with the analyses of the gas concentrations, the calculation of fluxes, and the required safety measures. Since non-upland agricultural lands (i.e. flooded paddy soils) are steadily increasing, a section is devoted to the specificities of GHG measurements in these ecosystems. Specialised techniques are also required for GHG measurements in aquatic systems (i.e. rivers), which are often affected by the transfer of nutrients from agricultural fields and therefore are an important indirect source of emission of GHGs. A simple, robust, and more precise methodof ammonia (NH3) emission measurement is also described.

scholarly journals An Overview on Atomization and Its Drug Delivery and Biomedical Applications

2021 ◽  
Vol 11 (11) ◽  
pp. 5173
Author(s):  
Anu Mohandas ◽  
Hongrong Luo ◽  
Seeram Ramakrishna
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Cost Effective ◽  
Spray Formation ◽  
Advantages And Disadvantages ◽  
Experimental Parameters ◽  
Different Types ◽  
Cost Effective Technique ◽  
User Friendly ◽  
Process Dimension

Atomization is an intricate operation involving unstable and complex networks with rupture and fusion of liquid molecules. There are diverse details that typify the spray formation, which are the technique and configuration of the atomization process, dimension and structure of the nozzle, experimental parameters, etc. Ultimately, the process generates fine sprays from the bulk of a liquid. Some examples of atomization that we come across in our day-to-day life are antiperspirant or hair spray, shower head, garden sprinkler, or cologne mist. In this review paper we are briefly discussing the theoretical steps taking place in an atomization technique. The instabilities of the jet and sheet are explained to understand the underlying theory that breaks the jet or sheet into droplets. Different types of atomization processes based on the energy sources are also summarized to give an idea about the advantages and disadvantages of these techniques. We are also discussing the various biomedical applications of the electrohydrodynamic atomization and its potential to use as a drug delivery system. In short, this paper is trying to demonstrate the diverse applications of atomization to show its potency as a user friendly and cost-effective technique for various purposes.

scholarly journals Comparative Study of Different SDLC Models

2021 ◽  
Vol 9 (11) ◽  
pp. 73-80
Author(s):  
Aparna Gupta
Keyword(s):  
Life Cycle ◽  
Software Development ◽  
Development Process ◽  
Cost Effective ◽  
Software Development Process ◽  
Application Development ◽  
Advantages And Disadvantages ◽  
Development Life Cycle ◽  
Software Development Life Cycle ◽  
Life Cycle Models

Abstract: The Software Development Life Cycle (SDLC) refers to a methodology with clearly defined processes for creating highquality software which are cost effective and reliable. This method of software developing process is quite systematic and structural. SDLC defines the framework that has different activities and tasks to be administered during the software development process. Software development process is quite complex, and to do it without any proper planning would be inefficient. So, we use these SDLC models to make the Software development process simple and systematic. There are various software development life cycle models that are used in the software development process, all having their own advantages and limitations. In this paper, we have included six of these SDLC models - Waterfall Model, Spiral Model, V Model, Agile Model, Iterative Model and Rapid Application Development (RAD) Model. These Software Development processes have their own Advantages and Disadvantages, and the main purpose of this paper is to explain these models and know the difference between them. Keywords: Software Development life cycle, Models, Risk Analysis, Framework, SRS.

A Review of 21 iPad Applications for Augmentative and Alternative Communication Purposes

2012 ◽  
Vol 21 (2) ◽  
pp. 60-71 ◽  
Author(s):  
Ashley Alliano ◽  
Kimberly Herriger ◽  
Anthony D. Koutsoftas ◽  
Theresa E. Bartolotta
Keyword(s):  
Augmentative And Alternative Communication ◽  
Cost Effective ◽  
Alternative Form ◽  
Alternative Communication ◽  
Text To Speech ◽  
Reference Guide ◽  
Expressive Communication ◽  
Communication Needs ◽  
User Friendly ◽  
Ipad Applications

Abstract Using the iPad tablet for Augmentative and Alternative Communication (AAC) purposes can facilitate many communicative needs, is cost-effective, and is socially acceptable. Many individuals with communication difficulties can use iPad applications (apps) to augment communication, provide an alternative form of communication, or target receptive and expressive language goals. In this paper, we will review a collection of iPad apps that can be used to address a variety of receptive and expressive communication needs. Based on recommendations from Gosnell, Costello, and Shane (2011), we describe the features of 21 apps that can serve as a reference guide for speech-language pathologists. We systematically identified 21 apps that use symbols only, symbols and text-to-speech, and text-to-speech only. We provide descriptions of the purpose of each app, along with the following feature descriptions: speech settings, representation, display, feedback features, rate enhancement, access, motor competencies, and cost. In this review, we describe these apps and how individuals with complex communication needs can use them for a variety of communication purposes and to target a variety of treatment goals. We present information in a user-friendly table format that clinicians can use as a reference guide.

Platelet monitoring for PCI

2009 ◽  
Vol 29 (04) ◽  
pp. 376-380 ◽  
Author(s):  
D. Capodanno ◽  
D. J. Angiolillo
Keyword(s):  
Interindividual Variability ◽  
State Of The Art ◽  
Coronary Intervention ◽  
Functional Tests ◽  
Treatment Regimens ◽  
Advantages And Disadvantages ◽  
Coronary Syndrome ◽  
Combined Use ◽  
Increased Risk ◽  
Percutaneous Coronary

SummaryDespite the clinical benefit associated with the combined use of aspirin and clopidogrel in patients with acute coronary syndrome or those undergoing percutaneous coronary intervention, a considerable interindividual variability in response to these drugs have been consistently reported. There is a growing interest on applying platelet functional tests with the goal of identifying patients at increased risk of recurrent ischaemic events and potentially tailoring antiplatelet treatment regimens.This manuscript will review the state of the art on the most commonly available platelet functional tests, describing their advantages and disadvantages and exploring their applicability in clinical practice.

Corncob Waste Based Adsorbent for Solid Phase Extraction of Tartrazine in Carbonated Drinks and Analytical Method using Ultra Performance Liquid Chromatography-Mass Spectrometry

2020 ◽  
Vol 16 (7) ◽  
pp. 924-932
Author(s):  
Yasmeen Mutlaq Ghazi Al Shamari ◽  
Saikh Mohammad Wabaidur ◽  
Abdulrahman Abdullah Alwarthan ◽  
Moonis Ali Khan ◽  
Masoom Raza Siddiqui
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Solid Phase Extraction ◽  
Solid Phase ◽  
Cost Effective ◽  
Ultra Performance Liquid Chromatography ◽  
Phase Extraction ◽  
Food Dye ◽  
Hyphenated Technique

Background : A new method has been developed for the determination of food dye tartrazine in soft drinks. Tartrazine is determined by hyphenated technique Ultra Performance Liquid Chromatography coupled with Mass spectrometry. The solid-phase extraction was used for the extraction of tartrazine. Methods: For the LC-MS analysis of tartrazine acetonitrile, water (80:20) was used as a mobile phase whereas, the C-18 column was selected as the stationary phase. The chromatographic run was allowed for 1 min. The adsorbent of the solid-phase extraction was synthesized from the waste corn cob. Results: Method found to be linear in the range of 0.1 mg L-1 - 10 mg L-1, limits of detection and quantitation were found to be 0.0165 mgL-1 and 0.055 mgL-1, respectively. Tartrazine, in the real sample, was found to be 20.39 mgL-1 and 83.26 mgL-1. Conclusion: The developed UPLC-MS method is rapid, simple, precise and can be used for the quantitative analysis of tartrazine. The solid-phase extraction also involves a cost-effective procedure for extraction as it does not involve the commercial cartridge.

scholarly journals Catalogue of hazards: a fundamental part for the safe design of surgical robots

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Lukas Theisgen ◽  
Florian Strauch ◽  
Matías de la Fuente ◽  
Klaus Radermacher
Keyword(s):  
Development Process ◽  
New Technologies ◽  
State Of The Art ◽  
Hazard Identification ◽  
Surgical Robots ◽  
Safety Measures ◽  
Fundamental Part ◽  
Phases Of Development ◽  
Early Phases ◽  
Intended Use

AbstractRisk classes defined by MDR and FDA for state-of-the-art surgical robots based on their intended use are not suitable as indicators for their hazard potential. While there is a lack of safety regulation for an increasing degree of automation as well as the degree of invasiveness into the patient’s body, adverse events have increased in the last decade. Thus, an outright identification of hazards as part of the risk analysis over the complete development process and life cycle of a surgical robot is crucial, especially when introducing new technologies. For this reason, we present a comprehensive approach for hazard identification in early phases of development. With this multi-perspective approach, the number of hazards identified can be increased. Furthermore, a generic catalogue of hazards for surgical robots has been established by categorising the results. The catalogue serves as a data pool for risk analyses and holds the potential to reduce hazards through safety measures already in the design process before becoming risks for the patient.

scholarly journals Recent Advances in Conventional Methods and Electrochemical Aptasensors for Mycotoxin Detection

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1437
Author(s):  
Jing Yi Ong ◽  
Andrew Pike ◽  
Ling Ling Tan
Keyword(s):  
Quantitative Analysis ◽  
Animal Feed ◽  
Cost Effective ◽  
Preventive Action ◽  
High Affinity ◽  
Recent Advances ◽  
Recognition Elements ◽  
Key Features ◽  
Pre Treatment ◽  
And Performance

The presence of mycotoxins in foodstuffs and feedstuffs is a serious concern for human health. The detection of mycotoxins is therefore necessary as a preventive action to avoid the harmful contamination of foodstuffs and animal feed. In comparison with the considerable expense of treating contaminated foodstuffs, early detection is a cost-effective way to ensure food safety. The high affinity of bio-recognition molecules to mycotoxins has led to the development of affinity columns for sample pre-treatment and the development of biosensors for the quantitative analysis of mycotoxins. Aptamers are a very attractive class of biological receptors that are currently in great demand for the development of new biosensors. In this review, the improvement in the materials and methodology, and the working principles and performance of both conventional and recently developed methods are discussed. The key features and applications of the fundamental recognition elements, such as antibodies and aptamers are addressed. Recent advances in aptasensors that are based on different electrochemical (EC) transducers are reviewed in detail, especially from the perspective of the diagnostic mechanism; in addition, a brief introduction of some commercially available mycotoxin detection kits is provided.

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