scholarly journals Diagnosis of Occlusal Tooth Wear Using 3D Imaging of Optical Coherence Tomography Ex Vivo

Sensors ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 6016
Author(s):  
Misa Kashiwa ◽  
Yasushi Shimada ◽  
Alireza Sadr ◽  
Masahiro Yoshiyama ◽  
Yasunori Sumi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Digital Radiography ◽  
3D Imaging ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Tooth Wear ◽  
Laser Scanning Microscopy ◽  
Optical Coherence ◽  
Significant Difference ◽  
Enamel Wear

The aim of this study was to assess the utility of 3D imaging of optical coherence tomography (OCT) for the diagnosis of occlusal tooth wear ex vivo. Sixty-three extracted human molars with or without visible tooth wear were collected to take digital intraoral radiography and 3D OCT images. The degree of tooth wear was evaluated by 12 examiners and scored using 4-rank scale: 1—slight enamel wear; 2—distinct enamel wear; 3—tooth wear with slight dentin exposure; 4—tooth wear with distinct involvement of dentin. The degree of tooth wear was validated by the histological view of confocal laser scanning microscopy (CLSM). The sensitivity, specificity, and area under the curve (AUC) of receiver operating characteristic analysis were calculated. Diagnostic accuracy was compared with the agreement with CLSM observation using weighted kappa. The results were statistically analyzed at a significance level of α = 0.05. Three-dimensional OCT showed significantly higher sensitivity (p < 0.05) for all the diagnostic thresholds of enamel wear and dentin exposure than digital radiography (0.82, 0.85, and 0.79 vs. 0.56, 0.52, and 0.57, respectively). Three-dimensional OCT showed higher AUC and kappa coefficients than digital radiography (p < 0.05), where mean AUC and Kappa values were 0.95 and 0.76 for OCT and 0.92 and 0.47 for radiography, respectively. No significant difference of specificity was observed (p > 0.05). Three-dimensional OCT could visualize and estimate the degree of tooth wear and detect the dentin exposure at the tooth wear surface accurately and reproducibly. Consequently, a new guideline for tooth wear assessment can be proposed using OCT.

Intraluminal three-dimensional optical coherence tomography – a tool for imaging of the Eustachian tube?

2019 ◽  
Vol 133 (2) ◽  
pp. 87-94 ◽  
Author(s):  
R Schuon ◽  
B Mrevlje ◽  
B Vollmar ◽  
T Lenarz ◽  
G Paasche
Keyword(s):  
Optical Coherence Tomography ◽  
Eustachian Tube ◽  
Cross Sections ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Diagnostic Value ◽  
Optical Coherence ◽  
Experimental Conditions ◽  
Non Invasive ◽  
Tube Dysfunction

AbstractObjectivesThe cause of Eustachian tube dysfunction often remains unclear. Therefore, this study aimed to examine the feasibility and possible diagnostic use of optical coherence tomography in the Eustachian tube ex vivo.MethodsTwo female blackface sheep cadaver heads were examined bilaterally. Three conditions of the Eustachian tube were investigated: closed (resting position), actively opened and stented. The findings were compared (and correlated) with segmented histological cross-sections.ResultsIntraluminal placement of the Eustachian tube with the optical coherence tomography catheter was performed without difficulty. Regarding the limited infiltration depth of optical coherence tomography, tissues can be differentiated. The localisation of the stent was accurate as was the lumen.ConclusionThe application of optical coherence tomography in the Eustachian tube under these experimental conditions is considered to be a feasible, rapid and non-invasive diagnostic method, with possible diagnostic value for determining the luminal shape and superficial lining tissue of the Eustachian tube.

scholarly journals The effect of commercial herbal toothpastes on dental wear: a comparative evaluation by Optical coherence tomography

2021 ◽  
Vol 10 (11) ◽  
pp. e161101119583
Author(s):  
Pedro Romeu de Mendonça Vila Nova ◽  
Paulo Cardoso Lins Filho ◽  
Marlon Ferreira Dias ◽  
Hilcia Mezzalira Teixeira ◽  
Silvana Orestes Cardoso ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Tooth Wear ◽  
Positive Control ◽  
Negative Control ◽  
Optical Coherence ◽  
Surface Wear ◽  
Dental Wear ◽  
Dentin Surface ◽  
Nail Polish ◽  
Enamel Wear

The purpose of this study was to compare the tooth wear in function of the use of different commercial herbal toothpastes through the analysis of Optical Coherence Tomography (OCT). Twenty bovine teeth were obtained and distributed in 4 groups (n = 5) according to the dentifrice used: G1: Captive Nature (Chamomile, Xylitol, Juá and Salvia); G2: Suavetex Content (Turmeric); G3: Colgate Triple Action (positive control); G4: distilled water (negative control). The samples were painted in the half of the fragment with nail polish so that only half of the fragment was brushed. The simulated brushing (20,000 cycles) was performed with linear movements, under static axial load of 200g and speed of 4.5 cycles per second. After this step, an analysis was performed through OCT and and the images obtained were evaluated to identify possible changes in the specimen surface. According to the qualitative analysis of the OCT images, enamel wear was not observed, since all measurements were null. Regarding the evaluation of dentin, surface wear was observed in all groups except G4, but G3 had the highest number of samples with surface wear around 21.32%. All dentifrices had abrasive wear on the dentin surface to a greater or lesser extent, but there was no wear on the enamel surface.

scholarly journals High-resolution three-dimensional optical coherence tomography imaging of kidney microanatomy ex vivo

2007 ◽  
Vol 12 (3) ◽  
pp. 034008 ◽  
Author(s):  
Yu Chen ◽  
Peter M. Andrews ◽  
Aaron D. Aguirre ◽  
Joseph M. Schmitt ◽  
James G. Fujimoto
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Optical Coherence ◽  
Tomography Imaging ◽  
Optical Coherence Tomography Imaging

scholarly journals Integrated Quad-Scanner Strategy-Based Optical Coherence Tomography for the Whole-Directional Volumetric Imaging of a Sample

Sensors ◽  
2021 ◽  
Vol 21 (4) ◽  
pp. 1305
Author(s):  
Sm Abu Saleah ◽  
Daewoon Seong ◽  
Sangyeob Han ◽  
Ruchire Eranga Wijesinghe ◽  
Naresh Kumar Ravichandran ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ex Vivo ◽  
3D Visualization ◽  
Three Dimensional ◽  
Physical Structure ◽  
Mouse Heart ◽  
Optical Coherence ◽  
Volume Data ◽  
Data Set ◽  
Inspection Method

Whole-directional scanning methodology is required to observe distinctive features of an entire physical structure with a three dimensional (3D) visualization. However, the implementation of whole-directional scanning is challenging for conventional optical coherence tomography (OCT), which scans a limited portion of the sample by utilizing unidirectional and bidirectional scanning methods. Therefore, in this paper an integrated quad-scanner (QS) strategy-based OCT method was implemented to obtain the whole-directional volumetry of a sample by employing four scanning arms installed around the sample. The simultaneous and sequential image acquisition capabilities are the conceptual key points of the proposed QS-OCT method, and were implemented using four precisely aligned scanning arms and applied in a complementary way according to the experimental criteria. To assess the feasibility of obtaining whole-directional morphological structures, a roll of Scotch tape, an ex vivo mouse heart, and kidney specimens were imaged and independently obtained tissue images at different directions were delicately merged to compose the 3D volume data set. The results revealed the potential merits of QS-OCT-based whole-directional imaging, which can be a favorable inspection method for various discoveries that require the dynamic coordinates of the whole physical structure.

scholarly journals Morpho-molecular ex vivo detection and grading of non-muscle-invasive bladder cancer using forward imaging probe based multimodal optical coherence tomography and Raman spectroscopy

The Analyst ◽  
2020 ◽  
Vol 145 (4) ◽  
pp. 1445-1456 ◽  
Author(s):  
Fabian Placzek ◽  
Eliana Cordero Bautista ◽  
Simon Kretschmer ◽  
Lara M. Wurster ◽  
Florian Knorr ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Optical Coherence Tomography ◽  
Imaging System ◽  
Ex Vivo ◽  
Large Field ◽  
Optical Coherence ◽  
Fiber Optic Probe ◽  
Optic Probe ◽  
Muscle Invasive

Characterization of bladder biopsies, using a combined fiber optic probe-based optical coherence tomography and Raman spectroscopy imaging system that allows a large field-of-view imaging and detection and grading of cancerous bladder lesions.

scholarly journals Non-invasive three-dimensional thickness analysis of oral epithelium based on optical coherence tomography—development and diagnostic performance

Heliyon ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. e06645
Author(s):  
Charlotte Theresa Trebing ◽  
Sinan Sen ◽  
Stefan Rues ◽  
Christopher Herpel ◽  
Maria Schöllhorn ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diagnostic Performance ◽  
Three Dimensional ◽  
Oral Epithelium ◽  
Optical Coherence ◽  
Non Invasive

scholarly journals Three-dimensional segmentation and depth-encoded visualization of choroidal vasculature using swept-source optical coherence tomography

2021 ◽  
pp. 153537022110285
Author(s):  
Hao Zhou ◽  
Tommaso Bacci ◽  
K Bailey Freund ◽  
Ruikang K Wang
Keyword(s):  
Optical Coherence Tomography ◽  
Three Dimensional ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Full Thickness ◽  
Swept Source ◽  
Automated Method ◽  
Choroidal Imaging ◽  
Choroidal Vasculature ◽  
Choroidal Vessels

The choroid provides nutritional support for the retinal pigment epithelium and photoreceptors. Choroidal dysfunction plays a major role in several of the most important causes of vision loss including age-related macular degeneration, myopic degeneration, and pachychoroid diseases such as central serous chorioretinopathy and polypoidal choroidal vasculopathy. We describe an imaging technique using depth-resolved swept-source optical coherence tomography (SS-OCT) that provides full-thickness three-dimensional (3D) visualization of choroidal anatomy including topographical features of individual vessels. Enrolled subjects with different clinical manifestations within the pachychoroid disease spectrum underwent 15 mm × 9 mm volume scans centered on the fovea. A fully automated method segmented the choroidal vessels using their hyporeflective lumens. Binarized choroidal vessels were rendered in a 3D viewer as a vascular network within a choroidal slab. The network of choroidal vessels was color depth-encoded with a reference to the Bruch’s membrane segmentation. Topographical features of the choroidal vasculature were characterized and compared with choroidal imaging obtained with indocyanine green angiography (ICGA) from the same subject. The en face SS-OCT projections of the larger choroid vessels closely resembled to that obtained with ICGA, with the automated SS-OCT approach proving additional depth-encoded 3D information. In 16 eyes with pachychoroid disease, the SS-OCT approach added clinically relevant structural details, including choroidal thickness and vessel depth, which the ICGA studies could not provide. Our technique appears to advance the in vivo visualization of the full-thickness choroid, successfully reveals the topographical features of choroidal vasculature, and shows potential for further quantitative analysis when compared with other choroidal imaging techniques. This improved visualization of choroidal vasculature and its 3D structure should provide an insight into choroid-related disease mechanisms as well as their responses to treatment.

Ex Vivo assessment of competent strut coverage after coronary stenting by optical coherence tomography

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
R Bhoite ◽  
H Jinnouchi ◽  
F Otsuka ◽  
Y Sato ◽  
A Sakamoto ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Predictive Value ◽  
Ex Vivo ◽  
High Sensitivity ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Neointimal Thickness ◽  
Stent Strut ◽  
Oct Imaging ◽  
Definition Of

Abstract Background In many studies, struts coverage is defined as &gt;0 mm of tissue overlying the stent struts by optical coherence tomography (OCT). However, this definition has never been validated using histology as the “gold standard”. The present study sought to assess the appropriate cut-off value of neointimal thickness of stent strut coverage by OCT using histology. Methods OCT imaging was performed on 39 human coronary arteries with stents from 25 patients at autopsy. A total of 165 cross-sectional images from 46 stents were co-registered with histology. The optimal cut-off value of strut coverage by OCT was determined. Strut coverage by histology was defined as endothelial cells with at least underlying two layers of smooth muscle cells. Considering the resolution of OCT is 10–20 μm, 3 different cut-off values (i.e. at ≥20, ≥40, and ≥60 μm) were assessed. Results A total of 2235 struts were evaluated by histology. Eventually, 1216 struts which were well-matched struts were analyzed in this study. By histology, uncovered struts were observed in 160 struts and covered struts were observed in 1056 struts. The broadly used definition of OCT-coverage which does not consider neointimal thickness yielded a poor specificity of 37.5% and high sensitivity 100%. Of 3 cut-off values, the cut-off value of &gt;40 μm was more accurate as compared to &gt;20 and &gt;60 mm [sensitivity (99.3%), specificity (91.0%), positive predictive value (98.6%), and negative predictive value (95.6%)] Conclusion The most accurate cut-off value was ≥40 μm neointimal thickness by OCT in order to identify stent strut coverage validated by histology. Funding Acknowledgement Type of funding source: None

Three-dimensional computational analysis of optical coherence tomography images for the detection of soft tissue sarcomas

2013 ◽  
Vol 19 (2) ◽  
pp. 021102 ◽  
Author(s):  
Shang Wang ◽  
Chih-Hao Liu ◽  
Valery P. Zakharov ◽  
Alexander J. Lazar ◽  
Raphael E. Pollock ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Soft Tissue ◽  
Computational Analysis ◽  
Three Dimensional ◽  
Soft Tissue Sarcomas ◽  
Optical Coherence
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