scholarly journals Advances in Optical Biosensors and Sensors Using Nanoporous Anodic Alumina

Sensors ◽  
2020 ◽  
Vol 20 (18) ◽  
pp. 5068
Author(s):  
Mahmoud Amouzadeh Tabrizi ◽  
Josep Ferre-Borrull ◽  
Lluis F. Marsal
Keyword(s):  
Heavy Ions ◽  
Review Paper ◽  
High Sensitivity ◽  
Anodic Alumina ◽  
Optical Biosensors ◽  
Sensor Applications ◽  
Nanoporous Anodic Alumina ◽  
Sensitivity And Selectivity ◽  
Good Potential ◽  
Gas Molecules

This review paper focuses on recent progress in optical biosensors using self-ordered nanoporous anodic alumina. We present the fabrication of self-ordered nanoporous anodic alumina, surface functionalization, and optical sensor applications. We show that self-ordered nanoporous anodic alumina has good potential for use in the fabrication of antibody-based (immunosensor), aptamer-based (aptasensor), gene-based (genosensor), peptide-based, and enzyme-based optical biosensors. The fabricated optical biosensors presented high sensitivity and selectivity. In addition, we also showed that the performance of the biosensors and the self-ordered nanoporous anodic alumina can be used for assessing biomolecules, heavy ions, and gas molecules.

scholarly journals Spatially Ordered Matrix of Nanostructured Tin–Tungsten Oxides Nanocomposites Formed by Ionic Layer Deposition for Gas Sensing

Sensors ◽  
2021 ◽  
Vol 21 (12) ◽  
pp. 4169
Author(s):  
Gennady Gorokh ◽  
Natalia Bogomazova ◽  
Abdelhafed Taleb ◽  
Valery Zhylinski ◽  
Timur Galkovsky ◽  
...  
Keyword(s):  
Tungsten Oxide ◽  
Gas Sensing ◽  
Oxide Films ◽  
High Sensitivity ◽  
Anodic Alumina ◽  
Film Deposition ◽  
Silicon Substrates ◽  
Layer By Layer ◽  
Gas Sensitivity ◽  
Nanoporous Anodic Alumina

The process of layer-by-layer ionic deposition of tin-tungsten oxide films on smooth silicon substrates and nanoporous anodic alumina matrices has been studied. To achieve the film deposition, solutions containing cationic SnF2 or SnCl2 and anionic Na2WO4 or (NH4)2O·WO3 precursors have been used. The effect of the solution compositions on the films deposition rates, morphology, composition, and properties was investigated. Possible mechanisms of tin-tungsten oxide films deposition into the pores and on the surface of anodic alumina are discussed. The electro-physical and gas-sensitive properties of nanostructured SnxWyOz films have been investigated. The prepared nanocomposites exhibit stable semiconductor properties characterized by high resistance and low temperature coefficient of electrical resistance of about 1.6 × 10−3 K−1. The sensitivity of the SnxWyOz films to 2 and 10 ppm concentrations of ammonia at 523 K was 0.35 and 1.17, respectively. At concentrations of 1 and 2 ppm of nitrogen dioxide, the sensitivity was 0.48 and 1.4, respectively, at a temperature of 473 K. At the temperature of 573 K, the sensitivity of 1.3 was obtained for 100 ppm of ethanol. The prepared nanostructured tin-tungsten oxide films showed promising gas-sensitivity, which makes them a good candidate for the manufacturing of gas sensors with high sensitivity and low power consumption.

Nanoporous Anodic Alumina Barcodes: Toward Smart Optical Biosensors

2012 ◽  
Vol 24 (8) ◽  
pp. 1050-1054 ◽  
Author(s):  
Abel Santos ◽  
Victor S. Balderrama ◽  
María Alba ◽  
Pilar Formentín ◽  
Josep Ferré-Borrull ◽  
...  
Keyword(s):  
Anodic Alumina ◽  
Optical Biosensors ◽  
Nanoporous Anodic Alumina

scholarly journals Real-Time Monitoring of Biotinylated Molecules Detection Dynamics in Nanoporous Anodic Alumina for Bio-Sensing

Nanomaterials ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 478 ◽  
Author(s):  
Laura Pol ◽  
Chris Eckstein ◽  
Laura Acosta ◽  
Elisabet Xifré-Pérez ◽  
Josep Ferré-Borrull ◽  
...  
Keyword(s):  
Surface Modification ◽  
Real Time ◽  
Anodic Alumina ◽  
Label Free ◽  
Real Time Monitoring ◽  
Helpful Tool ◽  
Nanoporous Anodic Alumina ◽  
Efficient Detection ◽  
Sensitivity And Selectivity ◽  
Molecule Model

The chemical modification, or functionalization, of the surfaces of nanomaterials is a key step to achieve biosensors with the best sensitivity and selectivity. The surface modification of biosensors usually comprises several modification steps that have to be optimized. Real-time monitoring of all the reactions taking place during such modification steps can be a highly helpful tool for optimization. In this work, we propose nanoporous anodic alumina (NAA) functionalized with the streptavidin-biotin complex as a platform towards label-free biosensors. Using reflective interferometric spectroscopy (RIfS), the streptavidin-biotin complex formation, using biotinylated thrombin as a molecule model, was monitored in real-time. The study compared the performance of different NAA pore sizes in order to achieve the highest response. Furthermore, the optimal streptavidin concentration that enabled the efficient detection of the biotinylated thrombin attachment was estimated. Finally, the ability of the NAA-RIfS system to quantify the concentration of biotinylated thrombin was evaluated. This study provides an optimized characterization method to monitor the chemical reactions that take place during the biotinylated molecules attachment within the NAA pores.

scholarly journals First-principles theoretical investigation of graphene layers for sensor applications

2017 ◽  
Vol 7 ◽  
pp. 184798041773764 ◽  
Author(s):  
Yoshitaka Fujimoto
Keyword(s):  
Carbon Nanotubes ◽  
First Principles ◽  
Density Functional ◽  
Gas Adsorption ◽  
High Sensitivity ◽  
Functional Study ◽  
Graphene Layers ◽  
Sensor Applications ◽  
Adsorption Effects ◽  
Gas Molecules

Graphene is expected to be a potential device material for sensor applications due to its high charge mobility and high sensitivity to adsorbates. This article reviews the first-principles density-functional study that clarifies gas adsorption effects on graphene layers doped with boron and nitrogen atoms. We show adsorption effects of not only common gas molecules but also environmentally polluting or toxic gas molecules on stabilities and structural properties of graphene layers and carbon nanotubes. We also show physical properties induced by the adsorption of the gas molecules and discuss the possibility to detect these gas molecules.

scholarly journals High-Density Plasmonic Nanoparticle Arrays Deposited on Nanoporous Anodic Alumina Templates for Optical Sensor Applications

Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 531 ◽  
Author(s):  
Uldis Malinovskis ◽  
Raimonds Poplausks ◽  
Donats Erts ◽  
Kerstin Ramser ◽  
Sigitas Tamulevičius ◽  
...  
Keyword(s):  
Nearest Neighbor ◽  
Resonant Scattering ◽  
Variable Density ◽  
Visible Spectral Range ◽  
Anodic Alumina ◽  
Metal Nanoparticle ◽  
Nanoparticle Arrays ◽  
Absorption Bands ◽  
Sensor Applications ◽  
Nanoporous Anodic Alumina

This study demonstrates a new, robust, and accessible deposition technique of metal nanoparticle arrays (NPAs), which uses nanoporous anodic alumina (NAA) as a template for capillary force-assisted convective colloid (40, 60, and 80 nm diameter Au) assembly. The NPA density and nanoparticle size can be independently tuned by the anodization conditions and colloid synthesis protocols. This enables production of non-touching variable-density NPAs with controllable gaps in the 20–60 nm range. The NPA nearest neighbor center distance in the present study was fixed to 100 nm by the choice of anodization protocol. The obtained Au NPAs have the resonant scattering maxima in the visible spectral range, with a refractometric sensitivity, which can be tuned by the variation of the array density. The thickness of the NAA layer in an Aluminum-NAA-NPA multilayer system enables further tuning of the resonance frequency and optimization for use with specific molecules, e.g., to avoid absorption bands. Applicability of the mentioned multilayers for colorimetric refractive index (RI) sensing is demonstrated. Their use as Surface-Enhanced Raman Scattering (SERS) substrates is tested using hemoglobin as a biological probe molecule.

scholarly journals Recent Advances in MXene Nanocomposite-Based Biosensors

Biosensors ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 185 ◽  
Author(s):  
Jinho Yoon ◽  
Minkyu Shin ◽  
Joungpyo Lim ◽  
Ji-Young Lee ◽  
Jeong-Woo Choi
Keyword(s):  
Inorganic Compounds ◽  
High Sensitivity ◽  
High Conductivity ◽  
Optical Biosensors ◽  
Electrochemical Biosensors ◽  
Synthesis Methods ◽  
Two Dimensional ◽  
Recent Advances ◽  
Sensitivity And Selectivity

The development of advanced biosensors with high sensitivity and selectivity is one of the most demanded concerns in the field of biosensors. To meet this requirement, up until now, numerous nanomaterials have been introduced to develop biosensors for achieving high sensitivity and selectivity. Among the latest nanomaterials attracting attention, MXene is one of the best materials for the development of biosensors because of its various superior properties. MXenes are two-dimensional inorganic compounds with few atomic layers that possess excellent characteristics including high conductivity and superior fluorescent, optical, and plasmonic properties. In this review, advanced biosensors developed on the basis of the MXene nanocomposite are discussed with the selective overview of recently reported studies. For this, introduction of the MXene including the definition, synthesis methods, and its properties are discussed. Next, MXene-based electrochemical biosensors and MXene-based fluorescent/optical biosensors are provided, which are developed on the basis of the exceptional properties of the MXene nanocomposite. This review will suggest the direction for use of the Mxene nanocomposite to develop advanced biosensors with high sensitivity and selectivity.

scholarly journals Advanced Nanoporous Anodic Alumina-Based Optical Sensors for Biomedical Applications

2021 ◽  
Vol 3 ◽  
Author(s):  
Silu Feng ◽  
Weiwei Ji
Keyword(s):  
Optical Sensors ◽  
Optical Biosensor ◽  
Nanoporous Structure ◽  
Optical Biosensors ◽  
Formation Mechanisms ◽  
Sensor Applications ◽  
Nanoporous Anodic Alumina ◽  
Reflectometric Interference Spectroscopy ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Close-packed hexagonal array nanopores are widely used both in research and industry. A self-ordered nanoporous structure makes anodic aluminum oxide (AAO) one of the most popular nanomaterials. This paper describes the main formation mechanisms for AAO, the AAO fabrication process, and optical sensor applications. The paper is focused on four types of AAO-based optical biosensor technology: surface-Enhanced Raman Scattering (SERS), surface Plasmon Resonance (SPR), reflectometric Interference Spectroscopy (RIfS), and photoluminescence Spectroscopy (PL). AAO-based optical biosensors feature very good selectivity, specificity, and reusability.

Effect of pore diameter in nanoporous anodic alumina optical biosensors

The Analyst ◽  
2015 ◽  
Vol 140 (14) ◽  
pp. 4848-4854 ◽  
Author(s):  
G. Macias ◽  
J. Ferré-Borrull ◽  
J. Pallarès ◽  
L. F. Marsal
Keyword(s):  
Pore Diameter ◽  
Anodic Alumina ◽  
Optical Biosensors ◽  
Nanoporous Anodic Alumina

This study demonstrates how it is possible to tune the sensitivity of nanoporous anodic alumina optical biosensors by adjusting pore diameter.

scholarly journals Nanoporous Anodic Alumina: A Versatile Platform for Optical Biosensors

Materials ◽  
2014 ◽  
Vol 7 (6) ◽  
pp. 4297-4320 ◽  
Author(s):  
Abel Santos ◽  
Tushar Kumeria ◽  
Dusan Losic
Keyword(s):  
Anodic Alumina ◽  
Optical Biosensors ◽  
Nanoporous Anodic Alumina

Fabrication of a one-dimensional tube-in-tube polypyrrole/tin oxide structure for highly sensitive DMMP sensor applications

2017 ◽  
Vol 5 (33) ◽  
pp. 17335-17340 ◽  
Author(s):  
Jaemoon Jun ◽  
Jun Seop Lee ◽  
Dong Hoon Shin ◽  
Jungkyun Oh ◽  
Wooyoung Kim ◽  
...  
Keyword(s):  
Gas Sensor ◽  
Tin Oxide ◽  
Vapor Deposition ◽  
High Sensitivity ◽  
Oxide Structure ◽  
One Dimensional ◽  
Sensor Applications ◽  
Highly Sensitive ◽  
Sensitivity And Selectivity

1D tube-in-tube polypyrrole/tin oxide structure was fabricated using electrospinning and vapor deposition polymerization to construct the DMMP gas sensor, which shows high sensitivity and selectivity.

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