scholarly journals Genetic Deep Convolutional Autoencoder Applied for Generative Continuous Arterial Blood Pressure via Photoplethysmography

Sensors ◽  
2020 ◽  
Vol 20 (14) ◽  
pp. 3829
Author(s):  
Muammar Sadrawi ◽  
Yin-Tsong Lin ◽  
Chien-Hung Lin ◽  
Bhekumuzi Mathunjwa ◽  
Shou-Zen Fan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Cross Validation ◽  
Huge Number ◽  
Patient Monitor ◽  
Arterial Blood ◽  
Convolutional Autoencoder ◽  
Data Generalization

Hypertension affects a huge number of people around the world. It also has a great contribution to cardiovascular- and renal-related diseases. This study investigates the ability of a deep convolutional autoencoder (DCAE) to generate continuous arterial blood pressure (ABP) by only utilizing photoplethysmography (PPG). A total of 18 patients are utilized. LeNet-5- and U-Net-based DCAEs, respectively abbreviated LDCAE and UDCAE, are compared to the MP60 IntelliVue Patient Monitor, as the gold standard. Moreover, in order to investigate the data generalization, the cross-validation (CV) method is conducted. The results show that the UDCAE provides superior results in producing the systolic blood pressure (SBP) estimation. Meanwhile, the LDCAE gives a slightly better result for the diastolic blood pressure (DBP) prediction. Finally, the genetic algorithm-based optimization deep convolutional autoencoder (GDCAE) is further administered to optimize the ensemble of the CV models. The results reveal that the GDCAE is superior to either the LDCAE or UDCAE. In conclusion, this study exhibits that systolic blood pressure (SBP) and diastolic blood pressure (DBP) can also be accurately achieved by only utilizing a single PPG signal.

scholarly journals A METHOD TO DETERMINE THE PERIPHERAL ARTERIAL BLOOD PRESSURE IN THE MOUSE

1941 ◽  
Vol 74 (1) ◽  
pp. 29-40 ◽  
Author(s):  
Philip D. McMaster
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Close Agreement ◽  
Carotid Arteries ◽  
Systolic Pressure ◽  
Arterial Blood ◽  
Relative Transparency ◽  
Direct Measurements ◽  
Peripheral Arterial

Advantage has been taken of the relative transparency of the claw of the mouse to devise a method, here described, to measure the blood pressure in the animal's leg. Direct measurements of the systolic blood pressure from the carotid arteries of anesthetized mice have also been made. Simultaneous blood pressure readings by both these methods applied to the same animal showed close agreement. The systolic pressure ranged from 60 to 126 mm. Hg, according to the conditions.

Effect of the Ace Inhibitor Ceronapril on Cerebral Blood flow in Hypertensive Patients

1996 ◽  
Vol 30 (6) ◽  
pp. 578-582 ◽  
Author(s):  
Neal R Cutler ◽  
John J Sramek ◽  
Azucena Luna ◽  
Ismael Mena ◽  
Eric P Brass ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Enzyme Inhibitor ◽  
Blood Pressure Response ◽  
Combined Therapy ◽  
Arterial Blood

Objective To assess the effect of the angiotensin-converting enzyme inhibitor ceronapril on cerebral blood flow (CBF) in patients with moderate hypertension. Design Patients received chlorthalidone 25 mg for 4 weeks, and if diastolic blood pressure remained in the range of 100–115 mm Hg, they were given titrated doses of ceronapril (10–40 mg/d based on blood pressure response) in addition to chlorthalidone for 9 weeks. Setting Outpatient research clinic. Subjects Eligible patients had moderate essential hypertension (diastolic blood pressure 100–115 mm Hg) assessed when the patients were receiving no medications. Thirteen patients were entered into the study; 1 withdrew for reasons unrelated to the study drug. Twelve patients (11 men, 1 woman; mean age 52 y) completed the study. Intervention Ceronapril, given with chlorthalidone. Main Outcome Measures CBF measurements were taken at the start and end of ceronapril therapy using intravenous 133Xe; blood pressures were determined weekly. Results Mean arterial blood pressure decreased from 130 ± 4 to 120 ±7 mm Hg after 4 weeks of chlorthalidone administration, and fell further to 108 ± 8 mm Hg after an additional 9 weeks of combined chlorthalidone-ceronapril therapy (p < 0.05). CBF fell from 44 ± 15 to 34 ± 5 mL/min/100 g during the 9 weeks of combined therapy (p = 0.05). No adverse effects consistent with decreased CBF were observed. The decrease in CBF was not linearly correlated with the change in systemic blood pressure, but was strongly correlated (r = –0.937; p < 0.001) with the initial CBF. Conclusions The decrease in mean arterial blood pressure was not associated with a decrease in CBF. Patients with high CBF may be predisposed to a decrease in CBF when treated with ceronapril and chlorthalidone.

scholarly journals The Effect of Rice Bran Extract on Arterial Blood Pressure, Hepatic Steatosis, and Inflammation in Mice Fed with a High-Fat Diet

2020 ◽  
Vol 2020 ◽  
pp. 1-9 ◽  
Author(s):  
Naphatsanan Duansak ◽  
Pritsana Piyabhan ◽  
Umarat Srisawat ◽  
Jarinyaporn Naowaboot ◽  
Nusiri Lerdvuthisopon ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
High Fat Diet ◽  
High Fat ◽  
Protein Levels ◽  
Arterial Blood ◽  
Cox 2 ◽  
And Oxidative Stress

Background. Inflammation and hypertension are primary mechanisms involving in obesity-associated adverse effects of a high-fat diet. The aim of this study was to evaluate the effects of rice bran extract (RBE) on arterial blood pressure, hepatic steatosis, inflammation, and oxidative stress in high-fat diet (HFD)-induced obese mice. Methods. Male ICR mice were divided into four groups, including a normal-diet control group, a high-fat diet (HFD) (60% kcal from fat) group, an HFD group treated with RBE (220 mg/kg/day), and an HFD group treated with 1100 mg/kg/day for eight weeks. Besides body weight and arterial blood pressure, we determined liver values of total cholesterol, triglyceride, as well as percent body fat, tumor necrosis factor-α (TNF-α), malondialdehyde (MDA), nuclear factor kappa-B (NF-κB), matrix metalloprotease-9 (MMP-9), cyclooxygenase-2 (COX-2), and mRNA endothelial nitric oxide synthase (eNOS). Results. The HFD group had increased body weight, increased systolic and diastolic blood pressure, liver total cholesterol, triglyceride, NF-κB, COX-2 and MMP-9 protein levels, and decreased mRNA eNOS in the aorta. Mice of the HFD group receiving RBE had reduced diastolic blood pressure, as well as significantly decreased liver and serum TNF-α and MDA levels in the liver, and reduced NF-κB levels in both the liver and heart. Conclusions. These results demonstrate that RBE decreases diastolic blood pressure, the liver lipid droplet accumulation, liver and myocardial NF-κB, myocardial COX-2 and MMP-9 protein levels, and oxidative stress. Moreover, RBE may improve endothelial function and may alleviate adverse health effects associated with obesity including obesity-associated hypertension.

scholarly journals Oral clonidine versus intravenous fentanyl in attenuation of hemodynamic responses to larngoscopy and endotracheal intubation: a comparative study

2019 ◽  
Vol 6 (3) ◽  
pp. 623
Author(s):  
Rukmini G. ◽  
Srinivas M. Reddy
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Endotracheal Intubation ◽  
Hemodynamic Responses ◽  
Cardiovascular Parameters ◽  
Oral Clonidine ◽  
Arterial Blood ◽  
Fentanyl Group

Background: During endotracheal intubation, it has been observed that there is evolvement of the responses of the circulatory in nature. These are difficult to control using the IV anesthetic drugs. Hence various agents are tried to overcome this drawback. Objective of research work was to study efficacy of oral clonidine on hemodynamic responses compared to IV fentanyl while patients undergo larngoscopy and endotracheal intubation.Methods: The patients were allocated into two groups of 30 each. i.e. 30 patients in clonidine group and 30 patients in fentanyl group. All the patients received were pre-medicated with glycoprrolate 0.2mg, ondansetron 4mg and tramadol 1mg/kg body weight. Cardiovascular parameters (heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure,) were recorded at the following intervals: pre-induction, after induction, at endotracheal intubation, one minute, three minutes and five minutes after intubation.Results: The heart rate was significantly more at various intervals in patients who belonged to fentanyl group and it was significantly lesser in clonidine group. The systolic blood pressure was significantly more at various intervals in patients who belonged to fentanyl group and it was significantly lesser in clonidine group. The diastolic blood pressure was significantly more at various intervals in patients who belonged to fentanyl group and it was significantly lesser in clonidine group. Similar was the case with mean arterial blood pressure.Conclusions: Clonidine has been found to be more effective than IV fentanyl in stabilizing the cardiovascular parameters. Not only that orally it is easier to administer and cost effective.

Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36) amide in rats

1994 ◽  
Vol 266 (3) ◽  
pp. E459-E466 ◽  
Author(s):  
J. M. Barragan ◽  
R. E. Rodriguez ◽  
E. Blazquez
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Moderate Increase ◽  
Minimal Effect ◽  
Arterial Blood ◽  
Glucagon Like Peptide ◽  
Glucagon Like Peptide 1

This study was designed to determine the effects of glucagon-like peptides (GLP) on arterial blood pressure and heart rate. Although glucagon caused a minimal effect and GLP-1-(1-37) produced a moderate increase of both systolic and diastolic blood pressure, GLP-1-(7-36) amide induced the greatest increases in both parameters. Systolic and diastolic blood pressure and heart rate values increased when doses of the peptides were increased. By contrast, GLP-2 did not modify either arterial blood pressure or heart rate values. To determine whether the effects of GLP-1-(7-36) amide were mediated through catecholamines, the rats were pretreated with reserpine, propranolol, or phentolamine before administration of the peptide. In these three experimental groups, GLP-1-(7-36) amide increases mean arterial blood pressure and heart rate to the same level or even greater than that observed in nonpretreated rats. These findings indicate that GLP-1-(7-36) amide significantly increases arterial blood pressure and heart rate and that these effects are not mediated through catecholamines.

Arterial Blood Pressure - The Pattern of Change in Twin Pregnancies

1985 ◽  
Vol 34 (3-4) ◽  
pp. 217-223 ◽  
Author(s):  
D.M. Campbell ◽  
A.J. Campbell
Keyword(s):  
Blood Pressure ◽  
Body Size ◽  
Weight Gain ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Diastolic Pressure ◽  
Arterial Blood ◽  
Pressure Changes ◽  
Twin Pregnancies ◽  
Weight Gain During Pregnancy

AbstractAn epidemiological study of all primigravid twin pregnancies delivered in Aberdeen between 1950 and 1969 was performed to determine the pattern of arterial blood pressure changes. There is a greater fall from non-pregnant levels in diastolic blood pressure by mid pregnancy and a greater rise of diastolic pressure by delivery. These changes are independent of age, body size and rate of weight gain during pregnancy. The expected increased incidence of proteinuric pre-eclampsia is also independent of rate of weight gain when defined for twin pregnancies.

scholarly journals Ambulatory arterial blood pressure monitoring in patients before and after thyroidectomy

2008 ◽  
Vol 65 (2) ◽  
pp. 135-139
Author(s):  
Branislava Ivanovic ◽  
Ivan Paunovic ◽  
Djordje Nikcevic ◽  
Dane Cvijanovic ◽  
Nevena Kalezic ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Thyroid Surgery ◽  
De Novo ◽  
Blood Pressure Monitoring ◽  
Ambulatory Monitoring ◽  
Clinical Syndrome ◽  
Control Group ◽  
Arterial Blood

Bacground/Aim. Increased values of thyroid hormones in the clinical syndrome of hyperthyreosis affect blood pressure values and its circadial variation. The aim of this study was to define the influence of hyperthyreosis on the values and circadial variations of arterial blood pressure, as well as to investigate the effect of thyroid surgery on blood pressure values. Methods. We compared the 24-hour averages of systolic and diastolic blood pressure, their variations and their reduction during the night between 20 female patients with hyperthyroidism and hypertension de novo and 20 healthy females. We compared the values of 24-hour ambulatory monitoring performed before the surgery with the values gathered two weeks after the surgery. Results. The 24-hour average systolic and diastolic blood pressure values were higher in the patients with hyperthyroidism than in the control group (p < 0.001). In the group of patients, the variations in blood pressure were significantly higher than they were in the group of healthy people (p < 0.001). The amplitude of the nocturnal reduction of blood pressure was also significantly lower in the patients with hyperthyroid status and hypertension, in comparison to the healthy persons (p < 0.001). Two weeks after the surgery, a significant reduction of blood pressure values (both for systolic and diastolic) appeared. Conclusion. The patients with hyperthyroidism- caused hypertension had higher systolic and diastolic blood pressure, higher variations in blood pressure and lower nocturnal reduction of blood pressure than healthy subjects. Thyroid surgery, as a control of thyroid function, optimised blood pressure very rapidly.

scholarly journals Association between the systolic arterial blood pressure level and inter-arm asymmetry

2014 ◽  
Vol 95 (3) ◽  
pp. 472-474
Author(s):  
P I Petrov
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Blood Pressure Level ◽  
Pressure Level ◽  
Hand Position ◽  
Arterial Blood ◽  
Automatic Blood Pressure ◽  
Systolic Arterial Blood Pressure ◽  
The Right

Aim. To determine the association between the systolic arterial blood pressure level and the inter-arm asymmetry measurements in healthy individuals. Methods. 580 healthy volunteers aged 20 to 60 years (401 females, 179 males) were included in the study. Arterial blood pressure was measured in both left and right wrists using an automatic blood pressure sensor with the detector of hand position in a quiet, comfortable environment. Depending on the systolic arterial blood pressure level on the left arm, subjects were distributed to 5 groups: the 1st - blood pressure of 99 mm Hg and lower; 2nd - 100-119; 3rd - 120-129; 4th - 130-139; 5th -140 and over. Each group were further subdivided to 3 subgroups depending on the inter-arm blood pressure level asymmetry (difference of blood pressure levels on both arms): 1st - symmetry, 2nd - acceptable asymmetry (not exceeding 15 mm Hg), 3rd - abnormal asymmetry (16 mm Hg and over). Results. The major part of the examined subjects had systolic arterial blood pressure level between 100 and 119 mm Hg, systolic blood pressure below 99 mm Hg was registered more rarely. Among 580 examined subjects, abnormal asymmetry was more frequently seen in patients with blood pressure below 99 mm Hg and exceeding 140 mm Hg, the lowest frewuency was in the group with blood pressure between 120 and 129 mm Hg. The right arm was the dominating arm for the asymmetry in subjects with blood pressure below 119 mm Hg, in other cases the dominating arm was not determined. Conclusion. The study demonstrates the presence of vascular inter-arm asymmetry in systolic blood pressure in individuals who perceive themselves as healthy. Inter-arm asymmetry depended on the level of systolic arterial blood pressure.

STUDY THE CHANGE OF ARTERIAL BLOOD PRESSURE MEASURED BY NON-INVASIVE AND INVASIVE METHODS IN CHILDREN WITH DENGUE HEMORRHAGIC FEVER SHOCK

2011 ◽  
pp. 101-107
Author(s):  
Anh Tuan Ha ◽  
Hung Viet Phan ◽  
Huu Hoa Pham
Keyword(s):  
Blood Pressure ◽  
Intensive Care Unit ◽  
Systolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Dengue Hemorrhagic Fever ◽  
Hemorrhagic Fever ◽  
Non Invasive ◽  
Arterial Blood ◽  
Significant Difference ◽  
Level 3

Objective: To study the change of arterial blood pressure measured by non-invasive (NIBP) and invasive (PA) methods in children with Dengue Hemorrhagic fever shock. Patients and methods: included 60 patients ≤ 15 years old and hospitalized with diagnosis of Dengue Hemorrhagic fever with shock (level 3, level 4) at intensive care unit of Can tho Children's Hospital. Each patient’s arterial blood pressure will be simultaneously measured by both NIBP and PA methods. Results: At the time of shock, value of systolic blood pressure measured by the NIBP was 100.7 ± 10.8 mmHg, which was higher than the values measured by the PA was 91.7 ± 8.9 mmHg (p<0.05). Differentiating between the two methods was 9.1 ± 9.4 mmHg. At the time of shock exit, value of systolic blood pressure measured by the NIBP was 104.4 ± 10.6 mm Hg and measured by the PA was 105.5 ± 12.3 mmHg. Differentiating between the two measurements was 12.3 ± 10.3 mmHg. Conclusion: There was a statistically significant difference of blood pressure values measured by two non-invasive and invasive methods at the time of shock.

scholarly journals Characteristics of gender-related circadian arterial blood pressure in healthy adolescents

Medicina ◽  
2008 ◽  
Vol 44 (10) ◽  
pp. 768 ◽  
Author(s):  
Žaneta Drižienė ◽  
Eitautė Jakutienė ◽  
Donatas Stakišaitis ◽  
Birutė Pundzienė ◽  
Audrius Sveikata
Keyword(s):  
Blood Pressure ◽  
Menstrual Cycle ◽  
Systolic Blood Pressure ◽  
Arterial Blood Pressure ◽  
Adolescent Girls ◽  
Cycle Phase ◽  
Circadian Blood Pressure ◽  
Arterial Blood ◽  
Study Results ◽  
Nighttime Blood Pressure

Objective. To define 24-h characteristics of arterial blood pressure in healthy adolescent girls and boys; to determine gender-related differences of blood pressure, its circadian pattern. Material and methods. The 24-h blood pressure was monitored hourly in healthy girls (n=22, without no account for the menstrual cycle phase) and boys (n=22). Additionally, blood pressure of adolescent girls (n=15) was examined during different phases of their menstrual cycle (follicular, ovulation, and luteal). Blood pressure was monitored with an auto-cuff automatic outpatient blood pressure monitor. Results. Investigation showed gender-related differences in 24-h blood pressure. Study results revealed the circadian blood pressure rhythm characterized by a period of low values during nighttime and an early morning increase in both adolescent groups. Nocturnal systolic blood pressure was higher (P<0.05) in boys than in girls in all phases of their menstrual cycle. Diurnal systolic blood pressure in boys was higher than in girls in their follicular phase (P<0.05). The day and night blood pressure differed between boys and girls (P<0.05). A dipping blood pressure pattern as a decrease in mean nighttime blood pressure as compared with mean daytime blood pressure was defined: 10.02±6.7% in girls (n=22) and 13±6.3% in boys (n=22), without genderrelated differences (P>0.05). There were no differences in blood pressure dipping among girls’ groups in different menstrual cycle phases (P>0.05). Adolescent boys showed a significant positive correlation between their mean diurnal blood pressure and height (P<0.05). Conclusion. The study proved gender-related arterial blood pressure differences in healthy adolescents. The results demonstrate the gender-specific circadian blood pressure rhythm pattern in both gender groups.

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