scholarly journals A Combined Deep-Learning and Lattice Boltzmann Model for Segmentation of the Hippocampus in MRI

Sensors ◽  
2020 ◽  
Vol 20 (13) ◽  
pp. 3628
Author(s):  
Yingqian Liu ◽  
Zhuangzhi Yan

Segmentation of the hippocampus (HC) in magnetic resonance imaging (MRI) is an essential step for diagnosis and monitoring of several clinical situations such as Alzheimer’s disease (AD), schizophrenia and epilepsy. Automatic segmentation of HC structures is challenging due to their small volume, complex shape, low contrast and discontinuous boundaries. The active contour model (ACM) with a statistical shape prior is robust. However, it is difficult to build a shape prior that is general enough to cover all possible shapes of the HC and that suffers the problems of complicated registration of the shape prior and the target object and of low efficiency. In this paper, we propose a semi-automatic model that combines a deep belief network (DBN) and the lattice Boltzmann (LB) method for the segmentation of HC. The training process of DBN consists of unsupervised bottom-up training and supervised training of a top restricted Boltzmann machine (RBM). Given an input image, the trained DBN is utilized to infer the patient-specific shape prior of the HC. The specific shape prior is not only used to determine the initial contour, but is also introduced into the LB model as part of the external force to refine the segmentation. We used a subset of OASIS-1 as the training set and the preliminary release of EADC-ADNI as the testing set. The segmentation results of our method have good correlation and consistency with the manual segmentation results.

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Ming Gu ◽  
Renfang Wang

A novel active contour model is proposed for segmentation images with inhomogeneity. Firstly, fractional order filter is defined by eight convolution masks corresponding to the image orientation in the eight compass directions. Then, the fractional order differentiation image is obtained and applied to the level set method. Secondly, we defined a new energy functional based on local image information and fractional order differentiation image; the proposed model not only can describe the input image more accurately but also can deal with intensity inhomogeneity. Local fitting term can enhance the ability of the model to deal with intensity inhomogeneity. The defined penalty term is used to reduce the occurrence of false boundaries. Finally, in order to eliminate the time-consuming step of reinitialization and ensure stable evolution of level set function, the Gaussian filtering method is used. Experiments on synthetic and real images show that the proposed model is efficient for images with intensity inhomogeneity and flexible to initial contour.


2018 ◽  
Vol 2018 ◽  
pp. 1-11
Author(s):  
Huiyan Jiang ◽  
Shaojie Li ◽  
Siqi Li

The automated segmentation of liver and tumor from CT images is of great importance in medical diagnoses and clinical treatment. However, accurate and automatic segmentation of liver and tumor is generally complicated due to the complex anatomical structures and low contrast. This paper proposes a registration-based organ positioning (ROP) and joint segmentation method for liver and tumor segmentation from CT images. First, a ROP method is developed to obtain liver’s bounding box accurately and efficiently. Second, a joint segmentation method based on fuzzy c-means (FCM) and extreme learning machine (ELM) is designed to perform coarse liver segmentation. Third, the coarse segmentation is regarded as the initial contour of active contour model (ACM) to refine liver boundary by considering the topological information. Finally, tumor segmentation is performed using another ELM. Experiments on two datasets demonstrate the performance advantages of our proposed method compared with other related works.


2021 ◽  
Vol 33 (3) ◽  
pp. 036607
Author(s):  
Y. Feng ◽  
J. Miranda-Fuentes ◽  
J. Jacob ◽  
P. Sagaut

2021 ◽  
pp. 1-19
Author(s):  
Maria Tamoor ◽  
Irfan Younas

Medical image segmentation is a key step to assist diagnosis of several diseases, and accuracy of a segmentation method is important for further treatments of different diseases. Different medical imaging modalities have different challenges such as intensity inhomogeneity, noise, low contrast, and ill-defined boundaries, which make automated segmentation a difficult task. To handle these issues, we propose a new fully automated method for medical image segmentation, which utilizes the advantages of thresholding and an active contour model. In this study, a Harris Hawks optimizer is applied to determine the optimal thresholding value, which is used to obtain the initial contour for segmentation. The obtained contour is further refined by using a spatially varying Gaussian kernel in the active contour model. The proposed method is then validated using a standard skin dataset (ISBI 2016), which consists of variable-sized lesions and different challenging artifacts, and a standard cardiac magnetic resonance dataset (ACDC, MICCAI 2017) with a wide spectrum of normal hearts, congenital heart diseases, and cardiac dysfunction. Experimental results show that the proposed method can effectively segment the region of interest and produce superior segmentation results for skin (overall Dice Score 0.90) and cardiac dataset (overall Dice Score 0.93), as compared to other state-of-the-art algorithms.


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