scholarly journals A Comprehensive Machine-Learning-Based Software Pipeline to Classify EEG Signals: A Case Study on PNES vs. Control Subjects

Sensors ◽  
2020 ◽  
Vol 20 (4) ◽  
pp. 1235
Author(s):  
Giuseppe Varone ◽  
Sara Gasparini ◽  
Edoardo Ferlazzo ◽  
Michele Ascoli ◽  
Giovanbattista Gaspare Tripodi ◽  
...  

The diagnosis of psychogenic nonepileptic seizures (PNES) by means of electroencephalography (EEG) is not a trivial task during clinical practice for neurologists. No clear PNES electrophysiological biomarker has yet been found, and the only tool available for diagnosis is video EEG monitoring with recording of a typical episode and clinical history of the subject. In this paper, a data-driven machine learning (ML) pipeline for classifying EEG segments (i.e., epochs) of PNES and healthy controls (CNT) is introduced. This software pipeline consists of a semiautomatic signal processing technique and a supervised ML classifier to aid clinical discriminative diagnosis of PNES by means of an EEG time series. In our ML pipeline, statistical features like the mean, standard deviation, kurtosis, and skewness are extracted in a power spectral density (PSD) map split up in five conventional EEG rhythms (delta, theta, alpha, beta, and the whole band, i.e., 1–32 Hz). Then, the feature vector is fed into three different supervised ML algorithms, namely, the support vector machine (SVM), linear discriminant analysis (LDA), and Bayesian network (BN), to perform EEG segment classification tasks for CNT vs. PNES. The performance of the pipeline algorithm was evaluated on a dataset of 20 EEG signals (10 PNES and 10 CNT) that was recorded in eyes-closed resting condition at the Regional Epilepsy Centre, Great Metropolitan Hospital of Reggio Calabria, University of Catanzaro, Italy. The experimental results showed that PNES vs. CNT discrimination tasks performed via the ML algorithm and validated with random split (RS) achieved an average accuracy of 0.97 ± 0.013 (RS-SVM), 0.99 ± 0.02 (RS-LDA), and 0.82 ± 0.109 (RS-BN). Meanwhile, with leave-one-out (LOO) validation, an average accuracy of 0.98 ± 0.0233 (LOO-SVM), 0.98 ± 0.124 (LOO-LDA), and 0.81 ± 0.109 (LOO-BN) was achieved. Our findings showed that BN was outperformed by SVM and LDA. The promising results of the proposed software pipeline suggest that it may be a valuable tool to support existing clinical diagnosis.

2018 ◽  
Vol 7 (2) ◽  
pp. 279-285
Author(s):  
Sandy Akbar Dewangga ◽  
Handayani Tjandrasa ◽  
Darlis Herumurti

Brain-computer interfaces have been explored for years with the intent of using human thoughts to control mechanical system. By capturing the transmission of signals directly from the human brain or electroencephalogram (EEG), human thoughts can be made as motion commands to the robot. This paper presents a prototype for an electroencephalogram (EEG) based brain-actuated robot control system using mental commands. In this study, Linear Discriminant Analysis (LDA) and Support Vector Machine (SVM) method were combined to establish the best model. Dataset containing features of EEG signals were obtained from the subject non-invasively using Emotiv EPOC headset. The best model was then used by Brain-Computer Interface (BCI) to classify the EEG signals into robot motion commands to control the robot directly. The result of the classification gave the average accuracy of 69.06%.


2021 ◽  
Vol 12 (2) ◽  
pp. 67-77
Author(s):  
Umme Farhana ◽  
Mst Jannatul Ferdous

In brain computer interface (BCI) systems, the electroencephalography (EEG) signals give a pathway to a motor disabled person to communicate outside using the brain signal and a computer. EEG signals of different motor imagery (MI) movements can be differentiated using an effective classification technique to aid a motor disabled patient. The purpose of this paper is to classify two different types of MI movement tasks, movement of the left hand and movement of the right foot EEG signals accurately. For this purpose we have used a publicly available dataset. Since the feature extraction for classification is an important task, so we have used popular common spatial pattern (CSP) method for spatial feature extraction. Two different machine learning classifiers named support vector machine (SVM) and K-nearest neighbor (KNN) have been used to verify the proposed method. We got the highest average results 95.55%, 98.73% and 92.38% in case of SVM and 93.5%, 98.73% and 90.15% in case of KNN for classification accuracy, sensitivity, and specificity, respectively when a Butterworth band-pass filter passed through [10–30] Hz. On the other hand accuracy came to 89.4% in [10-30] Hz when applying CSP for feature extraction and fisher linear discriminant analysis (FLDA) for classification on this dataset earlier. Journal of Engineering Science 12(2), 2021, 67-77


2019 ◽  
Vol 20 (5) ◽  
pp. 488-500 ◽  
Author(s):  
Yan Hu ◽  
Yi Lu ◽  
Shuo Wang ◽  
Mengying Zhang ◽  
Xiaosheng Qu ◽  
...  

Background: Globally the number of cancer patients and deaths are continuing to increase yearly, and cancer has, therefore, become one of the world&#039;s highest causes of morbidity and mortality. In recent years, the study of anticancer drugs has become one of the most popular medical topics. </P><P> Objective: In this review, in order to study the application of machine learning in predicting anticancer drugs activity, some machine learning approaches such as Linear Discriminant Analysis (LDA), Principal components analysis (PCA), Support Vector Machine (SVM), Random forest (RF), k-Nearest Neighbor (kNN), and Naïve Bayes (NB) were selected, and the examples of their applications in anticancer drugs design are listed. </P><P> Results: Machine learning contributes a lot to anticancer drugs design and helps researchers by saving time and is cost effective. However, it can only be an assisting tool for drug design. </P><P> Conclusion: This paper introduces the application of machine learning approaches in anticancer drug design. Many examples of success in identification and prediction in the area of anticancer drugs activity prediction are discussed, and the anticancer drugs research is still in active progress. Moreover, the merits of some web servers related to anticancer drugs are mentioned.


Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5135
Author(s):  
Ngoc-Dau Mai ◽  
Boon-Giin Lee ◽  
Wan-Young Chung

In this research, we develop an affective computing method based on machine learning for emotion recognition using a wireless protocol and a wearable electroencephalography (EEG) custom-designed device. The system collects EEG signals using an eight-electrode placement on the scalp; two of these electrodes were placed in the frontal lobe, and the other six electrodes were placed in the temporal lobe. We performed experiments on eight subjects while they watched emotive videos. Six entropy measures were employed for extracting suitable features from the EEG signals. Next, we evaluated our proposed models using three popular classifiers: a support vector machine (SVM), multi-layer perceptron (MLP), and one-dimensional convolutional neural network (1D-CNN) for emotion classification; both subject-dependent and subject-independent strategies were used. Our experiment results showed that the highest average accuracies achieved in the subject-dependent and subject-independent cases were 85.81% and 78.52%, respectively; these accuracies were achieved using a combination of the sample entropy measure and 1D-CNN. Moreover, our study investigates the T8 position (above the right ear) in the temporal lobe as the most critical channel among the proposed measurement positions for emotion classification through electrode selection. Our results prove the feasibility and efficiency of our proposed EEG-based affective computing method for emotion recognition in real-world applications.


2020 ◽  
Vol 10 (18) ◽  
pp. 6417 ◽  
Author(s):  
Emanuele Lattanzi ◽  
Giacomo Castellucci ◽  
Valerio Freschi

Most road accidents occur due to human fatigue, inattention, or drowsiness. Recently, machine learning technology has been successfully applied to identifying driving styles and recognizing unsafe behaviors starting from in-vehicle sensors signals such as vehicle and engine speed, throttle position, and engine load. In this work, we investigated the fusion of different external sensors, such as a gyroscope and a magnetometer, with in-vehicle sensors, to increase machine learning identification of unsafe driver behavior. Starting from those signals, we computed a set of features capable to accurately describe the behavior of the driver. A support vector machine and an artificial neural network were then trained and tested using several features calculated over more than 200 km of travel. The ground truth used to evaluate classification performances was obtained by means of an objective methodology based on the relationship between speed, and lateral and longitudinal acceleration of the vehicle. The classification results showed an average accuracy of about 88% using the SVM classifier and of about 90% using the neural network demonstrating the potential capability of the proposed methodology to identify unsafe driver behaviors.


2021 ◽  
Author(s):  
Zhong Zhao ◽  
Haiming Tang ◽  
Xiaobin Zhang ◽  
Xingda Qu ◽  
Jianping Lu

BACKGROUND Abnormal gaze behavior is a prominent feature of the autism spectrum disorder (ASD). Previous eye tracking studies had participants watch images (i.e., picture, video and webpage), and the application of machine learning (ML) on these data showed promising results in identify ASD individuals. Given the fact that gaze behavior differs in face-to-face interaction from image viewing tasks, no study has investigated whether natural social gaze behavior could accurately identify ASD. OBJECTIVE The objective of this study was to examine whether and what area of interest (AOI)-based features extracted from the natural social gaze behavior could identify ASD. METHODS Both children with ASD and typical development (TD) were eye-tracked when they were engaged in a face-to-face conversation with an interviewer. Four ML classifiers (support vector machine, SVM; linear discriminant analysis, LDA; decision tree, DT; and random forest, RF) were used to determine the maximum classification accuracy and the corresponding features. RESULTS A maximum classification accuracy of 84.62% were achieved with three classifiers (LDA, DT and RF). Results showed that the mouth, but not the eyes AOI, was a powerful feature in detecting ASD. CONCLUSIONS Natural gaze behavior could be leveraged to identify ASD, suggesting that ASD might be objectively screened with eye tracking technology in everyday social interaction. In addition, the comparison between our and previous findings suggests that eye tracking features that could identify ASD might be culture dependent and context sensitive.


2020 ◽  
Author(s):  
Nazrul Anuar Nayan ◽  
Hafifah Ab Hamid ◽  
Mohd Zubir Suboh ◽  
Noraidatulakma Abdullah ◽  
Rosmina Jaafar ◽  
...  

Abstract Background: Cardiovascular disease (CVD) is the leading cause of deaths worldwide. In 2017, CVD contributed to 13,503 deaths in Malaysia. The current approaches for CVD prediction are usually invasive and costly. Machine learning (ML) techniques allow an accurate prediction by utilizing the complex interactions among relevant risk factors. Results: This study presents a case–control study involving 60 participants from The Malaysian Cohort, which is a prospective population-based project. Five parameters, namely, the R–R interval and root mean square of successive differences extracted from electrocardiogram (ECG), systolic and diastolic blood pressures, and total cholesterol level, were statistically significant in predicting CVD. Six ML algorithms, namely, linear discriminant analysis, linear and quadratic support vector machines, decision tree, k-nearest neighbor, and artificial neural network (ANN), were evaluated to determine the most accurate classifier in predicting CVD risk. ANN, which achieved 90% specificity, 90% sensitivity, and 90% accuracy, demonstrated the highest prediction performance among the six algorithms. Conclusions: In summary, by utilizing ML techniques, ECG data can serve as a good parameter for CVD prediction among the Malaysian multiethnic population.


Author(s):  
S. R. Mani Sekhar ◽  
G. M. Siddesh

Machine learning is one of the important areas in the field of computer science. It helps to provide an optimized solution for the real-world problems by using past knowledge or previous experience data. There are different types of machine learning algorithms present in computer science. This chapter provides the overview of some selected machine learning algorithms such as linear regression, linear discriminant analysis, support vector machine, naive Bayes classifier, neural networks, and decision trees. Each of these methods is illustrated in detail with an example and R code, which in turn assists the reader to generate their own solutions for the given problems.


2020 ◽  
Vol 9 (4) ◽  
pp. 252 ◽  
Author(s):  
Kwanele Phinzi ◽  
Dávid Abriha ◽  
László Bertalan ◽  
Imre Holb ◽  
Szilárd Szabó

Gullies reduce both the quality and quantity of productive land, posing a serious threat to sustainable agriculture, hence, food security. Machine Learning (ML) algorithms are essential tools in the identification of gullies and can assist in strategic decision-making relevant to soil conservation. Nevertheless, accurate identification of gullies is a function of the selected ML algorithms, the image and number of classes used, i.e., binary (two classes) and multiclass. We applied Linear Discriminant Analysis (LDA), Support Vector Machine (SVM), and Random Forest (RF) on a Systeme Pour l’Observation de la Terre (SPOT-7) image to extract gullies and investigated whether the multiclass (m) approach can offer better classification accuracy than the binary (b) approach. Using repeated k-fold cross-validation, we generated 36 models. Our findings revealed that, of these models, both RFb (98.70%) and SVMm (98.01%) outperformed the LDA in terms of overall accuracy (OA). However, the LDAb (99.51%) recorded the highest producer’s accuracy (PA) but had low corresponding user’s accuracy (UA) with 18.5%. The binary approach was generally better than the multiclass approach; however, on class level, the multiclass approach outperformed the binary approach in gully identification. Despite low spectral resolution, the pan-sharpened SPOT-7 product successfully identified gullies. The proposed methodology is relatively simple, but practically sound, and can be used to monitor gullies within and beyond the study region.


2019 ◽  
Vol 11 (10) ◽  
pp. 1195 ◽  
Author(s):  
Minsang Kim ◽  
Myung-Sook Park ◽  
Jungho Im ◽  
Seonyoung Park ◽  
Myong-In Lee

This study compared detection skill for tropical cyclone (TC) formation using models based on three different machine learning (ML) algorithms-decision trees (DT), random forest (RF), and support vector machines (SVM)-and a model based on Linear Discriminant Analysis (LDA). Eight predictors were derived from WindSat satellite measurements of ocean surface wind and precipitation over the western North Pacific for 2005–2009. All of the ML approaches performed better with significantly higher hit rates ranging from 94 to 96% compared with LDA performance (~77%), although false alarm rate by MLs is slightly higher (21–28%) than that by LDA (~13%). Besides, MLs could detect TC formation at the time as early as 26–30 h before the first time diagnosed as tropical depression by the JTWC best track, which was also 5 to 9 h earlier than that by LDA. The skill differences across MLs were relatively smaller than difference between MLs and LDA. Large yearly variation in forecast lead time was common in all models due to the limitation in sampling from orbiting satellite. This study highlights that ML approaches provide an improved skill for detecting TC formation compared with conventional linear approaches.


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