scholarly journals Performance Validation of a Planar Hall Resistance Biosensor through Beta-Amyloid Biomarker

Sensors ◽  
2020 ◽  
Vol 20 (2) ◽  
pp. 434 ◽  
Author(s):  
SungJoon Kim ◽  
Sri Ramulu Torati ◽  
Artem Talantsev ◽  
ChangYeop Jeon ◽  
SungBae Lee ◽  
...  
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Second Harmonic ◽  
Signal To Noise Ratio ◽  
Point Of Care ◽  
Magnetic Sensors ◽  
Hall Resistance ◽  
Field Mode ◽  
Mode Method ◽  
Performance Validation

Magnetic sensors have great potential for biomedical applications, particularly, detection of magnetically-labeled biomolecules and cells. On the basis of the advantage of the planar Hall effect sensor, which consists of improved thermal stability as compared with other magnetic sensors, we have designed a portable biosensor platform that can detect magnetic labels without applying any external magnetic field. The trilayer sensor, with a composition of Ta (5 nm)/NiFe (10 nm)/Cu (x = 0 nm~1.2 nm)/IrMn (10 nm)/Ta (5 nm), was deposited on a silicon wafer using photolithography and a sputtering system, where the optimized sensor sensitivity was 6 μV/(Oe∙mA). The detection of the magnetic label was done by comparing the signals obtained in first harmonic AC mode (1f mode) using an external magnetic field and in the second harmonic AC mode (2f mode) with a self-field generated by current passing through the sensor. In addition, a technique for the β-amyloid biomarker-based antibody-antigen sandwich model was demonstrated for the detection of a series of concentrations of magnetic labels using the self-field mode method, where the signal-to-noise ratio (SNR) was high. The generated self-field was enough to detect an immobilized magnetic tag without an additional external magnetic field. Hence, it could be possible to reduce the device size to use the point-of-care testing using a portable circuit system.

scholarly journals The Effect of Arrive Angle of External Magnetic Field on The Shape of Hysteresis Curve Permalloy Ni80Fe20 By Simulation

2021 ◽  
Vol 4 (2) ◽  
pp. 102
Author(s):  
Merinda Lestari ◽  
Widia Nursiyanto ◽  
Agung Tjahjo Nugroho
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Finite Difference ◽  
Coercive Field ◽  
Incident Angle ◽  
Magnetic Sensor ◽  
Magnetic Sensors ◽  
Hysteresis Curve ◽  
Angle Of Incidence ◽  
Angle Variation

Magnetic sensor is a type of sensor that utilizes changes in resistance caused by changes in the magnetic field H or B. One of the suitable magnetic materials to be used as a study material for making magnetic sensors is permalloy Ni80Fe20. The reading error of the magnetic sensor of the Ni80Fe20 permalloy material affects hysteresis curve of the material and requires correction of the angle of incidence of the external magnetic field in order to provide accurate results on the storage media. In this our current research using Finite Difference OOMMF, we investigated the effect of the angle of incidence of the external magnetic field (H) on the hysteresis curve was carried out on an application based on. The research was conducted by reviewing the parameter literature of the Ni80Fe20 permalloy material and then compiling it in a script and simulating it on an application based on Finite Difference OOMMF. The data obtained from the simulation are normalized magnetization (m), external magnetic field H and coercivity field (Hc) which have been influenced by the angle of incidence. The results of the hysteresis curve at a size of 5 nm with a variation of the angle of incidence 0o are indicated by the value of the external magnetic field H of 10000 mT to -10000 mT with a coercive field Hc of 5000 mT to -5000 mT. The normalized magnetization value m is 1 to -1. The variation of the angle of incidence of 30o produces a coercive field Hc of -108.3 mT to 108.3 mT and a normalized magnetization of 0.86 to -0.86. The 45o incident angle variation produces a coercive field Hc -88.4 mT to 88.4 mT and a normalized magnetization of -0.7 to 0.7

scholarly journals Эффекты магнитного поля в экситонной генерации оптических гармоник

2020 ◽  
Vol 62 (9) ◽  
pp. 1459
Author(s):  
В.В. Павлов
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Harmonic Generation ◽  
Stark Effect ◽  
Second Harmonic ◽  
Wide Bandgap ◽  
Third Harmonic ◽  
Wide Bandgap Semiconductor ◽  
Conduction Bands ◽  
Resonance Magnetic Field

Mechanisms responsible for the optical harmonics generation in several classes of materials at excitonic transitions are considered. In the cubic semiconductor GaAs, magnetically induced second harmonic generation (SHG) was observed in the region of orbital quantization for the valence and conduction bands. An unusually strong third harmonic generation was detected in the region of the 1s exciton in an external magnetic field due to the exciton-polariton resonance. Magnetic field induced SHG was revealed in the hexagonal wide bandgap semiconductor ZnO at exciton resonances 1s, 2s, and 2p. Depending on the symmetry of the exciton states, the SHG mechanisms are determined by the spin and orbital Zeeman effects, and the magneto-Stark effect. Magnetically induced contribution to SHG was studied in the antiferromagnet Cr2O3 at exciton transitions in an external magnetic field.

scholarly journals Exstraordinary and planar Hall effects in thin permalloy films

2021 ◽  
pp. 53-60
Author(s):  
Victoryia I. Halauchyk ◽  
Michail G. Lukashevich
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Film Plane ◽  
Field Direction ◽  
Hall Resistance ◽  
Magnetic Field Direction ◽  
Full Width ◽  
Half Maximum ◽  
Hall Effects ◽  
The Magnetic Field

The Hall resistance hysteresis loops in thin (d = 80 –280 nm) magnetically ordered permalloy films (Ni0.8 Fe0.2) were studied at room temperature at different angles between the film plane and the magnetic field direction (φ = 0 –360°) (extraordinary and ordinary Hall effects), at different angles (θ = 0 – 90°) between the magnetic field direction and the flowing current (planar Hall effect at φ = 0°) in a magnetic field up to B = 1.25 T. The thin films were obtained on sitall dielectric substrate by ion beam sputtering. Sharp peaks of the Hall resistance were observed in the extraordinary and planar Hall effects during the magnetisation reversal of the films due to a change of the magnetisation direction with respect to the sampling current direction. In the extraordinary Hall effect the position and full width at half maximum of a peak is determined by the angle between the magnetic field direction and the film plane. It has been shown that as the direction of the external magnetic field approaches the spontaneous magnetisation direction, both the peak magnetic field position Bp and the full width at half maximum of the peak Δ Bp increase. In the angles range of φ = 0 – 90° Bp and Δ  Bp varies in the magnetic field range from Δ  В ≈ 0.2 to 5.0 mT. A non-monotonic dependence of the planar Hall resistance and its peak position on the angle between the flowing current and the magnetic field direction was detected. It is related to the change of the longitudinal and transverse components the resistance of the magnetically ordered solids by an external magnetic field. The values of the ordinary and extraordinary Hall effects coefficients have been determined: RH0 = 6 ⋅ 10–9 m3/C and RH1 = 3.2 ⋅ 10–8 m3/C, respectively.

A Frequency Modulation GMI Magnetic Sensor Base on Inverter Multivibrator with Longitudinal Excitation

2013 ◽  
Vol 423-426 ◽  
pp. 2303-2307
Author(s):  
Bo Yang ◽  
Xiong Zhu Bu ◽  
Xian Jin Huang
Keyword(s):  
Magnetic Field ◽  
Frequency Modulation ◽  
Signal To Noise Ratio ◽  
Excitation Frequency ◽  
Magnetic Sensors ◽  
High Signal ◽  
Static Characteristics ◽  
Bias Magnetic Field ◽  
Excellent Performance ◽  
Longitudinal Excitation

Frequency Modulation (FM) GMI Magnetic Sensors has excellent performance in high signal-to-noise ratio and low power consumption. In this article, the FM magnetic sensors with longitudinal excitation are presented. The inductance of the sensing head versus the excitation frequency and the external magnetic field is tested by the impedance analyzer. The results show that the inductance is sensitive with the excitation frequency from 200kHz to 600kHz. The bias magnetic field generated by a permanent magnet is used to make the sensing head working at a linear region with the highest sensitivity. Three kinds of magnetic sensors with different inverter multivibrators circuits are illustrated and their static characteristics are provided through calibration experiments and data analysis. It shows that the first type has the highest sensitivity (41.0kHz/Oe) and the third type has the best linearity.

SECOND-HARMONIC GENERATION OF THE SURFACE MAGNETOPLASMON ON THE LATERAL SURFACE OF THE SEMICONDUCTOR SUPERLATTICE BOUNDED BY A METAL

1995 ◽  
Vol 02 (05) ◽  
pp. 579-585 ◽  
Author(s):  
N.A. AZARENKOV ◽  
I.B. DENISENKO ◽  
K.N. OSTRIKOV
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Second Harmonic Generation ◽  
Harmonic Generation ◽  
Lateral Surface ◽  
Second Harmonic ◽  
Dielectric Tensor ◽  
Generation Process ◽  
Two Dimensional ◽  
Semiconductor Superlattice

The resonant second-harmonic generation process of the surface magnetoplasma wave (SM) propagating across an external magnetic field on the lateral surface of the semiconductor superlattice bounded by a metal is studied. The lateral surface is perpendicular to the layers of the periodic structure and is parallel to the directions of the superlattice axis and the external magnetic field. The latter is assumed to quantize the electrodynamical properties of two-dimensional conducting layers of the semiconductor superlattice. The consideration is carried out in the approximation of the continuous anisotropic medium characterized by an effective dielectric tensor of the superlattice. The numerical estimates showing the efficiency of the second-harmonic generation are carried out for superlattices on the base of GaAs-AlGaAs heterostructures.

Fourier Analysis for Orthogonal and Parallel Fluxgate

2015 ◽  
Vol 644 ◽  
pp. 270-273 ◽  
Author(s):  
N. Hadjigeorgiou ◽  
C. Konstantopoulos ◽  
D. Masxas
Keyword(s):  
Magnetic Field ◽  
External Magnetic Field ◽  
Fourier Analysis ◽  
Magnetic Sensors ◽  
Experimental Process

Magnetic sensors have been, for many decades, the industrial standard for a variety of applications due to many unique advantages they possess, compared to other sensor types. The purpose of the experimental process in this paper, was initially to note (ascertain) if the orthogonal and parallel fluxgate sensors work properly and secondly to observe the reaction of the external magnetic field on their harmonics.

scholarly journals Simulation and improvements of a magnetic flux sensor for application in immunomagnetic biosensing platforms

2021 ◽  
Author(s):  
Kan Wang ◽  
TangAn Li ◽  
Bo Cao ◽  
Hao Xu ◽  
Wei Zheng ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Flux ◽  
Limit Of Detection ◽  
Signal To Noise Ratio ◽  
Point Of Care ◽  
Test Strip ◽  
Magnetic Field Measurement ◽  
Element Analysis ◽  
Sensor Structure ◽  
Flux Sensor

In recent years, point-of-care testing (POCT) has become a topical issue. Lateral flow immunoassay strategies based on magnetic nanoparticles (MNPs) are important POCT elements due to their sensitive quantification of biological materials via MNP magnetic field measurement. In this study, we designed a magnetic flux sensor for use in immunomagnetic biosensing platforms, incorporating a mathematical model and computer simulation strategy. The system used field programmable gate array (FPGA) as the control chip, synthesized excitation signals and excited coils to generate excitation magnetic fields. Also, the stepping motor was controlled to drive the test strip at a uniform speed through the sensor detection area. A differential configuration strategy was used for sensor pick-up coils to assess MNP influence on the magnetic flux, which was insensitive to background magnetic interference and common-mode noise. These factors significantly enhanced the signal-to-noise ratio of the sensor. The magnetic flux sensor structure was optimized, and response magnetic field characteristics of MNP on test strips analyzed using finite element analysis (FEA) simulations. System performance was evaluated by testing human chorionic gonadotropin (HCG), which demonstrated a linear performance, with a limit of detection of 0.0098 mIU/mL. This system may be used to identify other target analytes in different application settings.

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