scholarly journals Bovine Serum Albumin Protein-Based Liquid Crystal Biosensors for Optical Detection of Toxic Heavy Metals in Water

Sensors ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 298 ◽  
Author(s):  
Noor ul Amin ◽  
Humaira Masood Siddiqi ◽  
Yang Kun Lin ◽  
Zakir Hussain ◽  
Nasir Majeed
Keyword(s):  
Heavy Metal ◽  
Liquid Crystal ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Metal Ions ◽  
Bovine Serum ◽  
Heavy Metal Ions ◽  
Limit Of Detection ◽  
Optical Image ◽  
Toxic Heavy Metals

A new methodology involving the use of Bovine Serum Albumin (BSA) as a probe and liquid crystal (LC) as a signal reporter for the detection of heavy metal ions in water at neutral pH was developed. BSA acted as a multi-dentate ligand for the detection of multiple metal ions. The LC sensor was fabricated by immobilizing 3 µg mL−1 BSA solution on dimethyloctadecyl-[3-(trimethoxysilyl)propyl]ammonium chloride (DMOAP)-coated glass slides. In the absence of heavy metal ions, a dark optical image was observed, while in their presence, a dark optical image turned to bright. The optical response was characterized by using a polarized optical microscope (POM). The BSA based LC sensor selectively detected toxic metal ions as compared to s block metal ions and ammonium ions in water. Moreover, the limit of detection was found to be very low (i.e., 1 nM) for the developed new biosensor in comparison to reported biosensors.

A bovine serum albumin-coated magnetoelastic biosensor for the wireless detection of heavy metal ions

2018 ◽  
Vol 256 ◽  
pp. 318-324 ◽  
Author(s):  
Xing Guo ◽  
Shengbo Sang ◽  
Aoqun Jian ◽  
Shuang Gao ◽  
Qianqian Duan ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Metal Ions ◽  
Bovine Serum ◽  
Heavy Metal Ions

Influence of metal ions on thermal aggregation of bovine serum albumin: Aggregation kinetics and structural changes

2009 ◽  
Vol 103 (12) ◽  
pp. 1729-1738 ◽  
Author(s):  
Giovanna Navarra ◽  
Anna Tinti ◽  
Maurizio Leone ◽  
Valeria Militello ◽  
Armida Torreggiani
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Metal Ions ◽  
Bovine Serum ◽  
Structural Changes ◽  
Aggregation Kinetics ◽  
Thermal Aggregation

Use of liquid crystal to study the interactions of alkyl polyglycosides with gelatin and bovine serum albumin

2016 ◽  
Vol 27 (6) ◽  
pp. 852-856 ◽  
Author(s):  
Zhi-Jian Liao ◽  
Si-Nan Du ◽  
Yang Luo ◽  
Fang Zuo ◽  
Jian-Bin Luo
Keyword(s):  
Liquid Crystal ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Alkyl Polyglycosides

Deciphering the positional impact of chlorine in a new series of berberine analogues towards the superb-selective “turn-on” hydrophobic signaling of bovine serum albumin at physiological pH

2020 ◽  
Vol 44 (5) ◽  
pp. 1761-1771 ◽  
Author(s):  
Gopal Chandra Jana ◽  
Sk Nayim ◽  
Nandan Kumar Sahoo ◽  
Somnath Das ◽  
Mt Nasima Aktara ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Limit Of Detection ◽  
Selective Detection ◽  
Turn On

We report a new 9-O-benzyl substituted berberine analogue for the selective detection of BSA with a limit of detection value of 3.30 nM.

scholarly journals Removing Metal Ions from Water with Graphene–Bovine Serum Albumin Hybrid Membrane

Nanomaterials ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 276 ◽  
Author(s):  
Xiaoqing Yu ◽  
Shuwei Sun ◽  
Lin Zhou ◽  
Zhicong Miao ◽  
Xiaoyuan Zhang ◽  
...  
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Metal Ions ◽  
Metal Binding ◽  
Bovine Serum ◽  
Large Scale ◽  
Selective Adsorption ◽  
Hybrid Membrane ◽  
Transporter Protein ◽  
Metal Ions Detection

Here we report the fabrication of graphene oxide (GO)-based membranes covalently combined with bovine serum albumin (BSA) for metal ions detection. In this system, BSA acts as a transporter protein in the membrane and endows the membrane with selective recognition of Co2+, Cu2+, AuCl4−, and Fe2+. Combining the metal-binding ability of BSA and the large surface area of GO, the hybrid membrane can be used as a water purification strategy to selectively absorb a large amount of AuCl4− from HAuCl4 solution. Moreover, BSA could reduce the membrane-immobilized AuCl4− by adding sodium borohydride (NaBH4). Interestingly, adsorption experiments on three kinds of metal ions showed that the GO–BSA membrane had good selective adsorption of Co2+ compared with Cu2+ and Fe2+. The morphology and composition changes of the membrane were observed with atomic force microscopy (AFM) and Raman spectroscopy, respectively. It is expected that this facile strategy for fabricating large-scale graphene-biomolecule membranes will spark inspirations in the development of functional nanomaterials and wastewater purification.

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