scholarly journals Electrochemical Nanocomposite Single-Use Sensor for Dopamine Detection

Sensors ◽  
2019 ◽  
Vol 19 (14) ◽  
pp. 3097 ◽  
Author(s):  
Giulia Selvolini ◽  
Cinzia Lazzarini ◽  
Giovanna Marrazza
Keyword(s):  
Limit Of Detection ◽  
Differential Pulse ◽  
Sensor Response ◽  
Sensor Surface ◽  
Serum Samples ◽  
Dopamine Detection ◽  
Sensitive Sensor ◽  
Single Use ◽  
Pulse Voltammetry ◽  
Nanocomposite Sensor

In this work, we report the development of a simple and sensitive sensor based on graphite screen-printed electrodes (GSPEs) modified by a nanocomposite film for dopamine (DA) detection. The sensor was realized by electrodepositing polyaniline (PANI) and gold nanoparticles (AuNPs) onto the graphite working electrode. The sensor surface was fully characterized by means of the cyclic voltammetry (CV) technique using [Fe(CN)6]4−/3− and [Ru(NH3)6]2+/3+ as redox probes. The electrochemical behavior of the nanocomposite sensor towards DA oxidation was assessed by differential pulse voltammetry (DPV) in phosphate buffer saline at physiological pH. The sensor response was found to be linearly related to DA concentration in the range 1–100 μM DA, with a limit of detection of 0.86 μM. The performance of the sensor in terms of reproducibility and selectivity was also studied. Finally, the sensor was successfully applied for a preliminary DA determination in human serum samples.

scholarly journals Development of a Label-Free Electrochemical Aptasensor for the Detection of Tau381 and its Preliminary Application in AD and Non-AD Patients’ Sera

Biosensors ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 84 ◽  
Author(s):  
Dan Tao ◽  
Bingqing Shui ◽  
Yingying Gu ◽  
Jing Cheng ◽  
Weiying Zhang ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Early Stage ◽  
Differential Pulse ◽  
Electrical Signal ◽  
Label Free ◽  
Modified Glassy Carbon Electrode ◽  
Serum Samples ◽  
Pulse Voltammetry ◽  
Aptamer Sensor ◽  
Preliminary Application

The electrochemical aptamer sensor has been designed for detecting tau381, a critical biomarker of Alzheimer′s disease in human serum. The aptasensor is obtained by immobilizing the aptamer on a carboxyl graphene/thionin/gold nanoparticle modified glassy-carbon electrode. As a probe and bridge molecule, thionin connected carboxyl graphene and gold nanoparticles, and gave the electrical signal. Under optimal conditions, the increment of differential pulse voltammetry signal increased linearly with the logarithm of tau381 concentration in the range from 1.0 pM to 100 pM, and limit of detection was 0.70 pM. The aptasensor reliability was evaluated by determining its selectivity, reproducibility, stability, detection limit, and recovery. Performance analysis of the tau381 aptasensor in 10 patients’ serum samples showed that the aptasensor could screen patients with and without Alzheimer′s disease. The proposed aptasensor has potential for use in clinically diagnosing Alzheimer′s disease in the early stage.

scholarly journals An efficient electrochemical sensing of hazardous catechol and hydroquinone at direct green 6 decorated carbon paste electrode

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
K. Chetankumar ◽  
B. E. Kumara Swamy ◽  
S. C. Sharma ◽  
S. A. Hariprasad
Keyword(s):  
Carbon Paste Electrode ◽  
Limit Of Detection ◽  
Tap Water ◽  
Differential Pulse ◽  
Electrochemical Sensing ◽  
Carbon Paste ◽  
Pulse Voltammetry ◽  
Two Peaks ◽  
Paste Electrode ◽  
Scanning Electron

AbstractIn this proposed work, direct green 6 (DG6) decorated carbon paste electrode (CPE) was fabricated for the efficient simultaneous and individual sensing of catechol (CA) and hydroquinone (HY). Electrochemical deeds of the CA and HY were carried out by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) at poly-DG6-modfied carbon paste electrode (Po-DG6-MCPE). Using scanning electron microscopy (SEM) studied the surface property of unmodified CPE (UCPE) and Po-DG6-MCPE. The decorated sensor displayed admirable electrocatalytic performance with fine stability, reproducibility, selectivity, low limit of detection (LLOD) for HY (0.11 μM) and CC (0.09 μM) and sensor process was originated to be adsorption-controlled phenomena. The Po-DG6-MCPE sensor exhibits well separated two peaks for HY and CA in CV and DPV analysis with potential difference of 0.098 V. Subsequently, the sensor was practically applied for the analysis in tap water and it consistent in-between for CA 93.25–100.16% and for HY 97.25–99.87% respectively.

scholarly journals Supramolecular assemblies of carbon nanocoils and tetraphenylporphyrin derivatives for sensing of catechol and hydroquinone in aqueous solution

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Syeda Aqsa Batool Bukhari ◽  
Habib Nasir ◽  
Lujun Pan ◽  
Mehroz Tasawar ◽  
Manzar Sohail ◽  
...  
Keyword(s):  
Electrochemical Impedance ◽  
Limit Of Detection ◽  
Linear Trend ◽  
Differential Pulse ◽  
Peak Potential ◽  
Limit Of Quantification ◽  
Efficient Detection ◽  
Good Repeatability ◽  
Ft Ir ◽  
Pulse Voltammetry

AbstractNon-enzymatic electrochemical detection of catechol (CC) and hydroquinone (HQ), the xenobiotic pollutants, was carried out at the surface of novel carbon nanocoils/zinc-tetraphenylporphyrin (CNCs/Zn-TPP) nanocomposite supported on glassy carbon electrode. The synergistic effect of chemoresponsive activity of Zn-TPP and a large surface area and electron transfer ability of CNCs lead to efficient detection of CC and HQ. The nanocomposite was characterized by using FT-IR, UV/vis. spectrophotometer, SEM and energy dispersive X-ray spectroscopy (EDS). Cyclic voltammetry, differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy were used for the electrochemical studies. CNCs/Zn-TPP/GCE nanosensor displayed a limit of detection (LOD), limit of quantification (LOQ) and sensitivity for catechol as 0.9 µM, 3.1 µM and 0.48 µA µM−1 cm−2, respectively in a concentration range of 25–1500 µM. Similarly, a linear trend in the concentration of hydroquinone detection was observed between 25 and 1500 µM with an LOD, LOQ and sensitivity of 1.5 µM, 5.1 µM and 0.35 µA µM−1 cm−2, respectively. DPV of binary mixture pictured well resolved peaks with anodic peak potential difference, ∆Epa(CC-HQ), of 110 mV showing efficient sensing of CC and HQ. The developed nanosensor exhibits stability for up to 30 days, better selectivity and good repeatability for eight measurements (4.5% for CC and 5.4% for HQ).

Enhanced Electrochemical Determination Of Riboflavin In Biological And Pharmaceutical Samples At Poly (Arginine) Modified Carbon Paste Electrode

2019 ◽  
Vol 14 (4) ◽  
pp. 216-223 ◽  
Author(s):  
Girish Tigari ◽  
J.G. Manjunatha ◽  
D.K. Ravishankar ◽  
G. Siddaraju
Keyword(s):  
Carbon Paste Electrode ◽  
Limit Of Detection ◽  
Phosphate Buffer Solution ◽  
Differential Pulse ◽  
Modified Carbon Paste Electrode ◽  
Current Response ◽  
Carbon Paste ◽  
Serum Samples ◽  
Buffer Solution ◽  
Paste Electrode

An electrogenerated Polyarginine modified carbon paste electrode (PAMCPE) was fabricated through a simple electropolymerization procedure. The devised electrode was characterized by cyclic voltammetry (CV) and Field Emission Scanning Electron Microscopy (FESEM). This electrode was utilized for electrocatalytic estimation of Riboflavin (RF) and its instantaneous resolution with ascorbic acid (AA) and folic acid (FA) in phosphate buffer solution (PBS) of pH 6.0 by differential pulse voltammetry (DPV). It was observed to be a very responsive electrode for the electrochemical detection and quantification of RF. It was revealed that PAMCPE generates higher current response towards RF contrast to the bare carbon paste electrode (BCPE). Under optimized condition, the RF oxidation current values were linearly reliant on the RF concentration increment with a limit of detection (LOD) of 9.3·10-8 M using DPV. The stable PAMCPE was effectively applied for estimation of RF in B-complex pill and complex human blood serum samples.

Sensitive Determination of Epinephrine in the Presence of Ascorbic Acid at Poly(diphenylamine sulfonic acid) Modified Sensor

2020 ◽  
Vol 18 (4) ◽  
pp. 253-258
Author(s):  
Gamze Erdoğdu
Keyword(s):  
Ascorbic Acid ◽  
Sulfonic Acid ◽  
Limit Of Detection ◽  
Phosphate Buffer Solution ◽  
Differential Pulse ◽  
Buffer Solution ◽  
Sensitive Determination ◽  
Pulse Voltammetry ◽  
Modified Sensor

A sensitive and simple modified sensor was prepared by electrodeposition of diphenylamine sulfonic acid (DPSA) to the glassy carbon electrode surface by cyclic voltammetry (CV) technique. The electrooxidation of epinephrine (EP) was accomplished by CV and differential pulse voltammetry at poly(DPSA) modified sensor. As a result of the findings, the current values were enhanced and both substances were separated at the modified sensor compared to the bare electrode. There was linearly between the oxidation current and concentration of EP from 0.2 to 100 μM in phosphate buffer solution at pH 7.0. The limit of detection was 5.0 nM and the sensitivity was 0.4205 μA/μM. The determination of EP was successfully and satisfactorily carried out in real samples such as human blood serum and urine at the poly(DPSA) sensor. To the best knowledge of this work, this is the first study that detect the EP in the presence of ascorbic acid at poly(DPSA) sensor in the literature.

scholarly journals Fabrication of a Selective Sensor Amplification Probe Modified with Multi-Component Zn2SnO4/SnO2 Heterostructured Microparticles as a Robust Electrocatalyst for Electrochemical Detection of Antibacterial Drug Secnidazole

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6700
Author(s):  
Ramaraj Sukanya ◽  
Karuppaiah Balamurugan ◽  
Shen-Ming Chen ◽  
Ramachandran Rajakumaran ◽  
K. Muthupandi ◽  
...  
Keyword(s):  
Blood Serum ◽  
Electrochemical Detection ◽  
Differential Pulse ◽  
Electrochemical Analysis ◽  
Antibacterial Drug ◽  
Linear Calibration ◽  
Serum Samples ◽  
Pulse Voltammetry ◽  
Related Compounds ◽  
Selective Sensor

In this study, we synthesized heterostructured zinc stannate/tin oxide microparticles (ZTO/TO MPs) by a simple coprecipitation method and used them as an effective electrode material for the electrochemical detection of the antibacterial drug secnidazole (SCZ). The as-prepared ZTO/TO MPs were characterized by XRD, Raman, FE-SEM, HR-TEM, EDX, and XPS analyses. The physiochemical studies clearly proved that the fabricated ZTO/TO MPs were formed in a heterostructure phase without other impurities. A glassy carbon electrode modified with the synthesized ZTO/TO MPs showed an excellent and improved electrocatalytic activity in the electrochemical reduction of SCZ. Using differential pulse voltammetry (DPV), an impressive linear calibration range, extending from 0.01 to 193 μM, was observed, coupled with a detection limit of 0.0054 μM and a sensitivity of 0.055 μA/μM. In addition, the ZTO/TO MPs/GCE showed very good selectivity for the detection of SCZ in the presence of a number of biological, inorganic, and structurally related compounds. Finally, the ZTO/TO MPs/GCE was investigated for the analysis of SCZ in human blood serum samples. A very good recovery was obtained when spiking the blood serum with SCZ, highlighting the good applicability of the ZTO/TO MPs/GCE for the electrochemical analysis of SCZ in complex biological samples.

scholarly journals An Electrochemical Sensor based on Electrodeposited CTAB Film on Glassy Carbon Electrode for Detection of Morphine

2019 ◽  
Vol 32 (1) ◽  
pp. 137-141
Author(s):  
Pinky Abraham ◽  
S. Renjini ◽  
V. Anithakumary ◽  
P.G. Chithra
Keyword(s):  
Thin Film ◽  
Glassy Carbon ◽  
Limit Of Detection ◽  
Differential Pulse ◽  
Carbon Electrode ◽  
Sensing Platform ◽  
Excellent Electrochemical Performance ◽  
Tertiary Amino ◽  
Pulse Voltammetry ◽  
Glassy Carbon Modified Electrode

A simple, effective and rapid method for the electrochemical detection of morphine is described based on glassy carbon modified electrode with poly(CTAB). In this work, poly(CTAB) thin film was generated through elecropolymerization of the surfactant CTAB. The formation of nanoporous thin film of poly(CTAB) was confirmed by field emission scanning electron microscopy (FESEM) with energy dispersive spectra (EDS) and Fourier transform infrared spectroscopy (FTIR). The electrochemical behavior of morphine is explained in terms of the anodic oxidation of its tertiary amino group. The limit of detection was calculated as 0.2 μM with a good regression between concentration and peak current of morphine by using differential pulse voltammetry within the range of 50 nM to 20 μM. The poly(CTAB)/GCE based sensor shows excellent electrochemical performance for the detection of morphine and this sensing platform can be effective for the detection of similar molecules.

Electrochemical Sensor for Acetaminophen Based on a Poly(diphenylamine sulfonic acid) Modified Sensor

2020 ◽  
Vol 18 (10) ◽  
pp. 739-744
Author(s):  
Gamze Erdogdu
Keyword(s):  
Sulfonic Acid ◽  
Limit Of Detection ◽  
Differential Pulse ◽  
Carbon Electrode ◽  
Buffer Solution ◽  
Real Samples ◽  
Oxidation Current ◽  
Pulse Voltammetry ◽  
Modified Sensor

A sensitive and simple modified sensor was prepared by electrodeposition of diphenylamine sulfonic acid (DPSA) to the glassy carbon electrode surface by cyclic voltammetry (CV) technique. The electrooxidation of Acetaminophen (AC) was accomplished by CV and differential pulse voltammetry at poly(DPSA) modified sensor. As a result of the findings, the current values were enhanced and both substances were separated at the modified sensor compared to the bare electrode. There was linearly between the oxidation current and concentration of AC from 0.0 to 100 μM in phospate buffer solution at pH 7.0. The limit of detection was 3.0 nM and the sensitivity was 0.4108 μA/μM. The determination of AC was successfully and satisfactorily carried out in real samples such as human blood serum and urine at the poly(DPSA) sensor. To the best knowledge of this work, this is the first study that detect the AC in the presence of ascorbic acid at poly(DPSA) sensor in the literature.

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