scholarly journals Time-Series Chlorophyll Fluorescence Imaging Reveals Dynamic Photosynthetic Fingerprints of sos Mutants to Drought Stress

Sensors ◽  
2019 ◽  
Vol 19 (12) ◽  
pp. 2649 ◽  
Author(s):  
Dawei Sun ◽  
Yueming Zhu ◽  
Haixia Xu ◽  
Yong He ◽  
Haiyan Cen
Keyword(s):  
Time Series ◽  
Chlorophyll Fluorescence ◽  
Drought Stress ◽  
Learning Algorithm ◽  
Function Analysis ◽  
Classification Model ◽  
Support Vector ◽  
Wild Type ◽  
K Nearest Neighbor ◽  
Linear Discriminant

Resistance to drought stress is one of the most favorable traits in breeding programs yet drought stress is one of the most poorly addressed biological processes for both phenomics and genetics. In this study, we investigated the potential of using a time-series chlorophyll fluorescence (ChlF) analysis to dissect the ChlF fingerprints of salt overly sensitive (SOS) mutants under drought stress. Principle component analysis (PCA) was used to identify a shifting pattern of different genotypes including sos mutants and wild type (WT) Col-0. A time-series deep-learning algorithm, sparse auto encoders (SAEs) neural network, was applied to extract time-series ChlF features which were used in four classification models including linear discriminant analysis (LDA), k-nearest neighbor classifier (KNN), Gaussian naive Bayes (NB) and support vector machine (SVM). The results showed that the discrimination accuracy of sos mutants SOS1-1, SOS2-3, and wild type Col-0 reached 95% with LDA classification model. Sequential forward selection (SFS) algorithm was used to obtain ChlF fingerprints of the shifting pattern, which could address the response of sos mutants and Col-0 to drought stress over time. Parameters including QY, NPQ and Fm, etc. were significantly different between sos mutants and WT. This research proved the potential of ChlF imaging for gene function analysis and the study of drought stress using ChlF in a time-series manner.

scholarly journals A Deep Learning Approach for Classification and Diagnosis of Parkinson’s Disease

2021 ◽  
Author(s):  
Monika Jyotiyana ◽  
Nishtha Kesswani ◽  
Munish Kumar
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Learning ◽  
Nearest Neighbor ◽  
Health Sector ◽  
Classification Model ◽  
Support Vector ◽  
Learning Approaches ◽  
K Nearest Neighbor ◽  
Linear Discriminant

Abstract Deep learning techniques are playing an important role in the classification and prediction of diseases. Undoubtedly deep learning has a promising future in the health sector, especially in medical imaging. The popularity of deep learning approaches is because of their ability to handle a large amount of data related to the patients with accuracy, reliability in a short span of time. However, the practitioners may take time in analyzing and generating reports. In this paper, we have proposed a Deep Neural Network-based classification model for Parkinson’s disease. Our proposed method is one such good example giving faster and more accurate results for the classification of Parkinson’s disease patients with excellent accuracy of 94.87%. Based on the attributes of the dataset of the patient, the model can be used for the identification of Parkinsonism's. We have also compared the results with other existing approaches like Linear Discriminant Analysis, Support Vector Machine, K-Nearest Neighbor, Decision Tree, Classification and Regression Trees, Random Forest, Linear Regression, Logistic Regression, Multi-Layer Perceptron, and Naive Bayes.

scholarly journals An Artificial Intelligence-Based Smart System for Early Glaucoma Recognition Using OCT Images

2021 ◽  
Vol 12 (4) ◽  
pp. 32-59
Author(s):  
Law Kumar Singh ◽  
Pooja ◽  
Hitendra Garg ◽  
Munish Khanna
Keyword(s):  
Vision Loss ◽  
Nearest Neighbor ◽  
Peripheral Vision ◽  
Learning Algorithm ◽  
Three Dimensional ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
Linear Discriminant ◽  
Glaucoma Diagnosis ◽  
Detection And Identification

Glaucoma is a progressive and constant eye disease that leads to a deficiency of peripheral vision and, at last, leads to irrevocable loss of vision. Detection and identification of glaucoma are essential for earlier treatment and to reduce vision loss. This motivates us to present a study on intelligent diagnosis system based on machine learning algorithm(s) for glaucoma identification using three-dimensional optical coherence tomography (OCT) data. This experimental work is attempted on 70 glaucomatous and 70 healthy eyes from combination of public (Mendeley) dataset and private dataset. Forty-five vital features were extracted using two approaches from the OCT images. K-nearest neighbor (KNN), linear discriminant analysis (LDA), decision tree, random forest, support vector machine (SVM) were applied for the categorization of OCT images among the glaucomatous and non-glaucomatous class. The largest AUC is achieved by KNN (0.97). The accuracy is obtained on fivefold cross-validation techniques. This study will facilitate to reach high standards in glaucoma diagnosis.

scholarly journals Sentiment Analysis on Corona Virus Pandemic Using Machine Learning Algorithm

2020 ◽  
Vol 4 (1) ◽  
pp. 86-96
Author(s):  
Ricky Risnantoyo ◽  
Arifin Nugroho ◽  
Kresna Mandara
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Sentiment Analysis ◽  
Learning Algorithm ◽  
Classification Model ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
The Public ◽  
Machine Learning Classification ◽  
Corona Virus

Corona virus outbreaks that occur in almost all countries in the world have an impact not only in the health sector, but also in other sectors such as tourism, finance, transportation, etc. This raises a variety of sentiments from the public with the emergence of corona virus as a trending topic on Twitter social media. Twitter was chosen by the public because it can disseminate information in real time and can see market reactions quickly. This research uses "tweet" data or public tweet related to "Corona Virus" to see how the sentiment polarity arises. Text mining techniques and three machine learning classification algorithms are used, including Naive Bayes, Support Vector Machine (SVM), K-Nearest Neighbor (K-NN) to build a tweet classification model of sentiments whether they have positive, negative, or neutral polarity. The highest test results are generated by the Support Vector Machine (SVM) algorithm with an accuracy value of 76.21%, a precision value of 78.04%, and a recall value of 71.42%.Keywords: Machine Learning, Corona Virus, Twitter, Sentiment Analysis.

Application of Machine Learning Approaches for the Design and Study of Anticancer Drugs

2019 ◽  
Vol 20 (5) ◽  
pp. 488-500 ◽  
Author(s):  
Yan Hu ◽  
Yi Lu ◽  
Shuo Wang ◽  
Mengying Zhang ◽  
Xiaosheng Qu ◽  
...  
Keyword(s):  
Machine Learning ◽  
Drug Design ◽  
Anticancer Drugs ◽  
Nearest Neighbor ◽  
Cost Effective ◽  
Support Vector ◽  
Learning Approaches ◽  
K Nearest Neighbor ◽  
Activity Prediction ◽  
Linear Discriminant

Background: Globally the number of cancer patients and deaths are continuing to increase yearly, and cancer has, therefore, become one of the world&#039;s highest causes of morbidity and mortality. In recent years, the study of anticancer drugs has become one of the most popular medical topics. </P><P> Objective: In this review, in order to study the application of machine learning in predicting anticancer drugs activity, some machine learning approaches such as Linear Discriminant Analysis (LDA), Principal components analysis (PCA), Support Vector Machine (SVM), Random forest (RF), k-Nearest Neighbor (kNN), and Naïve Bayes (NB) were selected, and the examples of their applications in anticancer drugs design are listed. </P><P> Results: Machine learning contributes a lot to anticancer drugs design and helps researchers by saving time and is cost effective. However, it can only be an assisting tool for drug design. </P><P> Conclusion: This paper introduces the application of machine learning approaches in anticancer drug design. Many examples of success in identification and prediction in the area of anticancer drugs activity prediction are discussed, and the anticancer drugs research is still in active progress. Moreover, the merits of some web servers related to anticancer drugs are mentioned.

Efficient detection of hacker community based on twitter data using complex networks and machine learning algorithm

2021 ◽  
pp. 1-17
Author(s):  
Ahmed Al-Tarawneh ◽  
Ja’afer Al-Saraireh
Keyword(s):  
Machine Learning ◽  
Complex Networks ◽  
Nearest Neighbor ◽  
Learning Algorithm ◽  
Machine Learning Algorithms ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
Efficient Detection ◽  
Suggested Keywords

Twitter is one of the most popular platforms used to share and post ideas. Hackers and anonymous attackers use these platforms maliciously, and their behavior can be used to predict the risk of future attacks, by gathering and classifying hackers’ tweets using machine-learning techniques. Previous approaches for detecting infected tweets are based on human efforts or text analysis, thus they are limited to capturing the hidden text between tweet lines. The main aim of this research paper is to enhance the efficiency of hacker detection for the Twitter platform using the complex networks technique with adapted machine learning algorithms. This work presents a methodology that collects a list of users with their followers who are sharing their posts that have similar interests from a hackers’ community on Twitter. The list is built based on a set of suggested keywords that are the commonly used terms by hackers in their tweets. After that, a complex network is generated for all users to find relations among them in terms of network centrality, closeness, and betweenness. After extracting these values, a dataset of the most influential users in the hacker community is assembled. Subsequently, tweets belonging to users in the extracted dataset are gathered and classified into positive and negative classes. The output of this process is utilized with a machine learning process by applying different algorithms. This research build and investigate an accurate dataset containing real users who belong to a hackers’ community. Correctly, classified instances were measured for accuracy using the average values of K-nearest neighbor, Naive Bayes, Random Tree, and the support vector machine techniques, demonstrating about 90% and 88% accuracy for cross-validation and percentage split respectively. Consequently, the proposed network cyber Twitter model is able to detect hackers, and determine if tweets pose a risk to future institutions and individuals to provide early warning of possible attacks.

scholarly journals IntelliFin: Advanced Stock Prediction using Hybrid ML and LSTM Model with Financial Indicators powered by Sentiment Determination using NLP

2020 ◽  
Vol 9 (5) ◽  
pp. 428-433
Keyword(s):  
Stock Market ◽  
Stock Prices ◽  
Stock Price ◽  
Nearest Neighbor ◽  
Learning Algorithm ◽  
Majority Voting ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
Financial History ◽  
The Right

Stock Trading has been one of the most important parts of the financial world for decades. People investing in the share market analyze the financial history of a corporation, the news related to it and study huge amounts of data so as to predict its stock price trend. The right investment i.e. buying and selling a company stock at the right time leads to monetary benefits and can make one a millionaire overnight. The stock market is an extremely fluctuating platform wherein data is produced in humongous quantities and is influenced by numerous disparate factors such as socio-political issues, financial activities like splits and dividends, news as well as rumors. This work proposes a novel system “IntelliFin” to predict the share market trend. The system uses the various stock market technical indicators along with the company's historical market data trends to predict the share prices. The system employs the sentiment determination of a company's financial and socio-political news for a more accurate prediction. This system is implemented using two models. The first is a hybrid LSTM model optimized by an ADAM optimizer. The other is a hybrid ML model which integrates a Support Vector Regressor, K-Nearest Neighbor classifier, an RF classifier and a Linear Regressor using a Majority Voting algorithm. Both models employ a sentiment analyzer to account for the news impacting the stock prices which is powered by NLP. The models are trained continuously using Reinforcement Learning implemented by the Q-Learning Algorithm to increase the consistency and accuracy. The project aims to support the inexperienced investors, who don't have enough experience in investing in the stock market and help them maximize their profit and minimize or eliminate the losses. The developed system will also serve as a tool for professional investors to help and aid their decision making.

Function Analysis of Drought Resistance Related Gene TaGAPCs and TaWRKYs in Wheat

2021 ◽  
Author(s):  
Qiuzhu Wang ◽  
Lin Zhang ◽  
Shushen Yang
Keyword(s):  
Transcription Factors ◽  
Drought Stress ◽  
Function Analysis ◽  
Severe Drought ◽  
Primary Metabolism ◽  
Wild Type ◽  
Drought Treatment ◽  
Biological Regulation ◽  
Wheat Seedlings ◽  
Differential Genes

Abstract Backgrounds: Wheat (Triticum aestivum L.) is one of the most important food crops in the world. It faces various abiotic stresses during its growth. Drought is one of the main factors limiting the growth and development of wheat. Severe drought stress will Lead to a decline in wheat production. Cytoplasmic glyceraldehyde-3-phosphate dehydrogenase (GAPC) is an important member of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) family, which is widely present in plant cytoplasm. Plants play an important role in the process of primary metabolism and stress resistance.Result: In this study, a comparative transcriptomic analysis of the TaGAPCs-RNAi strain of Changwu 134 and the wild-type wheat seedlings of Changwu 134 under natural drought conditions was carried out. A total of 30067 differentially expressed genes were screened in RNAi strains and wild-type strains, of which 19,959 genes were up-regulated in RNAi strains and 10,108 genes were down-regulated in transcription. GO analysis shows that differential genes are mainly enriched in biological regulation, cellular processes, metabolic processes, and responses to stimuli. KEGG analysis showed that the differential genes were mainly concentrated in the biosynthesis of phenylpropane, plant hormone signal transduction and flavonoid biosynthesis pathways. By analyzing the expression levels of differential transcription factors, the significantly down-regulated transcription factor WRKY family member TaWRKY2 / 22/28/29/33/40/47/52 in wheat was screened out. The TaWRKY28/33/40/47 gene silencing line was successfully obtained using the barley stripe mosaic virus (BSMV-VIGS) technology. The plants with TaWRKY28/33/40/47 gene silenced were subjected to natural drought treatment, and physiological and biochemical index tests were carried out. The results showed that the growth status of gene-silenced plants was worse than that of wild-type plants, and the relative water content and chlorophyll content decreased. The content of MDA, H2O2 and superoxide anion increases, the activity of antioxidant enzymes (SOD, POD, CAT) decreases, and the content of proline decreases. Conclusion: The results showed that TaGAPCs regulates the expression of some TaWRKYs transcription factors, activates antioxidant pathways, enhances tolerance of wheat to drought stress.

Cardiovascular Disease Prediction from Electrocardiogram by using Machine Learning Method: A Snapshot from the Subjects of the Malaysian Cohort

2020 ◽  
Author(s):  
Nazrul Anuar Nayan ◽  
Hafifah Ab Hamid ◽  
Mohd Zubir Suboh ◽  
Noraidatulakma Abdullah ◽  
Rosmina Jaafar ◽  
...  
Keyword(s):  
Machine Learning ◽  
Cardiovascular Disease ◽  
Nearest Neighbor ◽  
Total Cholesterol Level ◽  
Population Based ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
Cvd Risk ◽  
Linear Discriminant ◽  
Artificial Neural Network Ann

Abstract Background: Cardiovascular disease (CVD) is the leading cause of deaths worldwide. In 2017, CVD contributed to 13,503 deaths in Malaysia. The current approaches for CVD prediction are usually invasive and costly. Machine learning (ML) techniques allow an accurate prediction by utilizing the complex interactions among relevant risk factors. Results: This study presents a case–control study involving 60 participants from The Malaysian Cohort, which is a prospective population-based project. Five parameters, namely, the R–R interval and root mean square of successive differences extracted from electrocardiogram (ECG), systolic and diastolic blood pressures, and total cholesterol level, were statistically significant in predicting CVD. Six ML algorithms, namely, linear discriminant analysis, linear and quadratic support vector machines, decision tree, k-nearest neighbor, and artificial neural network (ANN), were evaluated to determine the most accurate classifier in predicting CVD risk. ANN, which achieved 90% specificity, 90% sensitivity, and 90% accuracy, demonstrated the highest prediction performance among the six algorithms. Conclusions: In summary, by utilizing ML techniques, ECG data can serve as a good parameter for CVD prediction among the Malaysian multiethnic population.

Classification of fish species from different ecosystems using the near infrared diffuse reflectance spectra of otoliths

2020 ◽  
Vol 28 (4) ◽  
pp. 224-235
Author(s):  
Irina M Benson ◽  
Beverly K Barnett ◽  
Thomas E Helser
Keyword(s):  
Discriminant Analysis ◽  
Spatial Variability ◽  
Near Infrared ◽  
Nir Spectroscopy ◽  
Principal Component ◽  
Classification Model ◽  
Support Vector ◽  
Otolith Chemistry ◽  
K Nearest Neighbor ◽  
Fisheries Science

Applications of Fourier transform near infrared (FT-NIR) spectroscopy in fisheries science are currently limited. This current analysis of otolith spectral data demonstrate the potential applicability of FT-NIR spectroscopy to otolith chemistry and spatial variability in fisheries science. The objective of this study was to examine the use of NIR spectroscopy as a tool to differentiate among marine fishes in four large marine ecosystems. We examined otoliths from 13 different species, with three of these species coming from different regions. Principal component analysis described the main directions along which the specimens were separated. The separation of species and their ecosystems may suggest interactions between fish phylogeny, ontogeny, and environmental conditions that can be evaluated using NIR spectroscopy. In order to discriminate spectra across ecosystems and species, four supervised classification model techniques were utilized: soft independent modelling of class analogies, support vector machine discriminant analysis, partial least squares discriminant analysis, and k-nearest neighbor analysis (KNN). This study showed that the best performing model to classify combined ecosystems, all four ecosystems, and species was the KNN model, which had an overall accuracy rate of 99.9%, 97.6%, and 91.5%, respectively. Results from this study suggest that further investigations are needed to determine applications of NIR spectroscopy to otolith chemistry and spatial variability.

scholarly journals A New Approach to Fall Detection Based on Improved Dual Parallel Channels Convolutional Neural Network

Sensors ◽  
2019 ◽  
Vol 19 (12) ◽  
pp. 2814 ◽  
Author(s):  
Xiaoguang Liu ◽  
Huanliang Li ◽  
Cunguang Lou ◽  
Tie Liang ◽  
Xiuling Liu ◽  
...  
Keyword(s):  
Neural Network ◽  
Convolutional Neural Network ◽  
Nearest Neighbor ◽  
Fall Detection ◽  
Classification Performance ◽  
Daily Activities ◽  
Support Vector ◽  
K Nearest Neighbor ◽  
Linear Discriminant ◽  
Parallel Channels

Falls are the major cause of fatal and non-fatal injury among people aged more than 65 years. Due to the grave consequences of the occurrence of falls, it is necessary to conduct thorough research on falls. This paper presents a method for the study of fall detection using surface electromyography (sEMG) based on an improved dual parallel channels convolutional neural network (IDPC-CNN). The proposed IDPC-CNN model is designed to identify falls from daily activities using the spectral features of sEMG. Firstly, the classification accuracy of time domain features and spectrograms are compared using linear discriminant analysis (LDA), k-nearest neighbor (KNN) and support vector machine (SVM). Results show that spectrograms provide a richer way to extract pattern information and better classification performance. Therefore, the spectrogram features of sEMG are selected as the input of IDPC-CNN to distinguish between daily activities and falls. Finally, The IDPC-CNN is compared with SVM and three different structure CNNs under the same conditions. Experimental results show that the proposed IDPC-CNN achieves 92.55% accuracy, 95.71% sensitivity and 91.7% specificity. Overall, The IDPC-CNN is more effective than the comparison in accuracy, efficiency, training and generalization.

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