scholarly journals Development of a Function-Integrative Sleeve for Medical Applications

Sensors ◽  
2019 ◽  
Vol 19 (11) ◽  
pp. 2588 ◽  
Author(s):  
Moritz Neubauer ◽  
Eric Häntzsche ◽  
Christina Pamporaki ◽  
Graeme Eisenhofer ◽  
Martin Dannemann ◽  
...  
Keyword(s):  
Blood Flow ◽  
Upper Extremity ◽  
Positive Impact ◽  
Diagnostic Procedures ◽  
Physiological Effects ◽  
User Friendliness ◽  
Clinical Investigations ◽  
Tumour Diagnosis ◽  
Local Warming

Function-integrative textiles bear the potential for a variety of applications in the medical field. Recent clinical investigations suggest that the application of a function-integrative fabric could have a positive impact on currently applied diagnostic procedures of a specific type of tumour. In this context, the fabric should enable local warming of a patient’s upper extremity as well as blood flow measurement. Existing solutions comprise a warming system but lack a measuring apparatus for blood flow determination. With regard to the quality of results of current diagnostic procedures, the local warming of the patients’ upper extremity and the simultaneous determination of the blood flow plateau are crucial. In the present paper, the development process of a function-integrative sleeve is introduced. Besides the development of an adaptable sleeve-design, the manufacturing process of an integrated warming system was also addressed. Furthermore, the identification of crucial physiological effects, using a Laser Doppler Perfusion Monitor, is introduced. During testing of the function-integrative sleeve, modulation of the desired physiological effects was observed. The results support the initial assumptions and dictate further investigations on increasing user-friendliness and cost-efficiency during adjusting and determining the physiological effects in the course of tumour diagnosis.

Assessment of the incorporation of revascularized fibula grafts used for mandibular reconstruction with F-18-PET

2001 ◽  
Vol 40 (02) ◽  
pp. 51-58 ◽  
Author(s):  
H. Schliephake ◽  
van den Hoff ◽  
W. H. Knapp ◽  
G. Berding
Keyword(s):  
Blood Flow ◽  
Regional Blood Flow ◽  
Venous Blood ◽  
Mandibular Reconstruction ◽  
Reference Region ◽  
Osteoblastic Activity ◽  
Non Union ◽  
Range Of Values ◽  
Measured Input

Summary Aim: Determination of the range of regional blood flow and fluoride influx during normal incorporation of revascularized fibula grafts used for mandibular reconstruction. Evaluation, if healing complications are preceded by typical deviations of these parameters from the normal range. Assessment of the potential influence of using “scaled population-derived” instead of “individually measured” input functions in quantitative analysis. Methods: Dynamic F-l 8-PET images and arterialized venous blood samples were obtained in 11 patients early and late after surgery. Based on kinetic modeling regional blood flow (K1) and fluoride influx (Kmlf) were determined. Results: In uncomplicated cases, early postoperative graft K1 - but not Kmlf -exceeded that of vertebrae as reference region. Kmn values obtained in graft necrosis (n = 2) were below the ranges of values observed in uncomplicated healing (0.01 13-0.0745 ml/min/ml) as well as that of the reference region (0.0154-0.0748). Knf values in mobile non-union were in the lower range - and those in rigid non-union in the upper range of values obtained in stable union (0.021 1-0.0694). If scaled population-derived instead of measured input functions were used for quantification, mean deviations of 23 ± 17% in K1 and 12 ± 16% in Kmlf were observed. Conclusions: Normal healing of predominantly cortical bone transplants is characterized by relatively low osteoblastic activity together with increased perfusion. It may be anticipated that transplant necrosis can be identified by showing markedly reduced F− influx. In case that measured input functions are not available, quantification with scaled population-derived input functions is appropriate if expected differences in quantitative parameters exceed 70%.

EVALUATION OF HYSTEROSALPINGOGRAPHY VERSUS LAPAROSCOPY IN THE DETERMINATION OF TUBAL FACTORS IN FEMALE INFERTILITY: A HOSPITAL BASED COMPARATIVE STUDY.

2020 ◽  
Vol 4 (9) ◽  
Author(s):  
Richa Choudhary ◽  
Rishikant Sinha
Keyword(s):  
Female Infertility ◽  
Diagnostic Methods ◽  
Panoramic View ◽  
Tubal Patency ◽  
Pelvic Organs ◽  
Clinical Investigations ◽  
Detailed Assessment ◽  
Reproductive Anatomy ◽  
Tubal Pathology

Objectives: Hysterosalpingography and laparoscopy both are the diagnostic methods for assessment of female infertility.  The present study was to compare the evaluation of hysterosalpingography (HSG) versus laparoscopy in determination of tubal factors in female infertility. Methods: Detailed assessment, physical examination and clinical investigations were performed in all 100 infertile female with age 20 years to 40 years. All patients were advised to perform digital HSG. Patients with an abnormal HSG underwent laparoscopy without delay, whereas in patients with a normal HSG, laparoscopy was performed three months after HSG. HSG is best scheduled during the 2nd -5th day interval immediately following the end of menstruation, to minimize risk for infection, avoid interference from intrauterine blood and clot, and to prevent any possibility that the procedure might be performed after conception. Results: Data was analysed by using IBM SPSS version 23 software.  All data was tabulated and percentages were calculated. Mean ± standard deviation was observed. Conclusions: Diagnostic laparoscopy is the gold standard in diagnosing tubal pathology and other intra-abdominal causes of infertility. Other hand, Hysterosalpingography is a frequently utilized diagnostic tool in the assessment of tubal status and detection of uterine anatomical defects in infertility. Hysterosalpingography and laparoscopy are not alternatives but complimentary investigations. But, inadequacy of hysterosalpingography (HSG) in determining the state of tubal patency, emphasizes the need for laparoscopy. Laparoscopy provides both a panoramic view of the pelvic reproductive anatomy and a magnified view of pelvic organs and peritoneal surfaces. Keywords: Female infertility, Tubal patency, HSG, Laparoscopy

Determination of renal blood flow by thermodilution method

1978 ◽  
Vol 38 (5) ◽  
pp. 495-499 ◽  
Author(s):  
Torbjörn Leivestad ◽  
Erling Brodwall ◽  
Svein Simonsen
Keyword(s):  
Blood Flow ◽  
Renal Blood Flow ◽  
Thermodilution Method

Novel Technologıes and Nanotoxıcology of Medıcal Implants

2020 ◽  
Vol 16 ◽  
Author(s):  
Ramazan Akçan ◽  
Halit Canberk Aydogan ◽  
Mahmut Şerif Yıldırım ◽  
Burak Taştekin ◽  
Necdet Sağlam
Keyword(s):  
Human Health ◽  
Human Body ◽  
Diagnostic Procedures ◽  
Toxic Effects ◽  
Medical Implants ◽  
Healthcare Applications ◽  
Detailed Review ◽  
Novel Technologies ◽  
Technological Developments

Background/aim: Use of nanomaterials in the healthcare applications increases in parallel to technological developments. It is frequently utilized in diagnostic procedures, medications and in therapeutic implementations. Nanomaterials take place among key components of medical implants, which might be responsible for certain toxic effects on human health at nano-level. In this review, nanotoxicological effects, toxicity determination of nanobiomaterials used in human body and their effects on human health are discussed. Material and Method: A detailed review of related literature was performed and evaluated as per nanomaterials and medical implants. Results and Conclusion: The nanotoxic effects of the materials applied to human body and the determination of its toxicity are important. Determination of toxicity for each nanomaterial requires a detailed and multifactorial assessment considering the properties of these materials. There are limited studies in the literature regarding the toxic effects of nanomaterials used in medical implants. Although these implants are potentially biocompatible and biodegradable, it is highly important to discuss nanotoxicological characteristics of medical implant.

scholarly journals Neurological determination of death in isolated brainstem lesions: A case report to highlight the issues involved

2019 ◽  
Vol 21 (3) ◽  
pp. 269-273 ◽  
Author(s):  
Alex Manara ◽  
Panayiotis Varelas ◽  
Martin Smith
Keyword(s):  
Blood Flow ◽  
Case Report ◽  
Cerebral Circulation ◽  
Posterior Circulation ◽  
Determination Of Death ◽  
International Consensus ◽  
Brainstem Lesions ◽  
Posterior Cerebral Circulation ◽  
Isolated Brainstem

The neurological determination of death in patients with isolated brainstem lesions or by disruption of the posterior cerebral circulation is uncommon and many intensivists may never see such a case in their career. It is also the only major difference between the “whole brain” and “brain stem” formulations for the neurological determination of death. We present a case of a patient with infarction of the structures supplied by the posterior cerebral circulation in whom death was diagnosed using neurological criteria, to illustrate the issues involved. We also suggest that international consensus may be achieved if ancillary tests, such as CT angiography, are made mandatory in this situation o demonstrate loss of blood flow in the anterior cerebral circulation as well the posterior circulation.

scholarly journals Doppler ultrasound in pregnancy – quality requirements of DEGUM and clinical application (part 2)

2021 ◽  
Author(s):  
Renaldo Faber ◽  
Kai-Sven Heling ◽  
Horst Steiner ◽  
Ulrich Gembruch
Keyword(s):  
Blood Flow ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Umbilical Artery ◽  
Prophylactic Treatment ◽  
Doppler Sonography ◽  
First Trimester ◽  
Ductus Venosus ◽  
Fetal Diagnosis

AbstractThis second part on Doppler sonography in prenatal medicine and obstetrics reviews its clinical applications. While this has not become the initially anticipated screening tool, it is used for the diagnosis and surveillance of a variety of fetal pathologies. For example, the sonography-based determination of uterine artery blood flow indices is an important parameter for the first trimester multimodal preeclampsia risk assessment, increasing accuracy and providing indication for the prophylactic treatment with aspirin. It also has significant implications for the diagnosis and surveillance of growth-restricted fetuses in the second and third trimesters through Doppler-sonographic analysis of umbilical artery, middle cerebral artery and ductus venosus. Here, especially the hemodynamics of the ductus venosus provides a critical criterium for birth management of severe, early-onset FGR before 34 + 0 weeks of gestation. Further, determination of maximum blood flow velocity of the middle cerebral artery is a central parameter in fetal diagnosis of anemia which has been significantly improved by this analysis. However, it is important to note that the mentioned improvements can only be achieved through highest methodological quality. Importantly, all these analyses are also applied to twins and higher order multiples. Here, for the differential diagnosis of specific complications such as TTTS, TAPS and TRAP, the application of Doppler sonography has become indispensable. To conclude, the successful application of Doppler sonography requires both exact methodology and precise pathophysiological interpretation of the data.

Tc-99m HMPAO/SPECT Determination of Regional Cerebral Blood Flow Changes in Schizophrenics

1990 ◽  
Vol 15 (12) ◽  
pp. 904-907 ◽  
Author(s):  
BELKIS ERBAS ◽  
HAKAN KUMBASAR ◽  
G??NAYDIN ERBENGI ◽  
COSKUN BEKDIK
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Regional Cerebral Blood Flow ◽  
Regional Cerebral Blood ◽  
Hmpao Spect ◽  
Flow Changes

scholarly journals Extraction Methods for the Determination of Regional Renal Blood Flow

1979 ◽  
Vol 84 (2) ◽  
pp. 163-171 ◽  
Author(s):  
A.-C. Ericson ◽  
M. Sjöquist ◽  
H. R. Ulfendahl
Keyword(s):  
Blood Flow ◽  
Renal Blood Flow ◽  
Extraction Methods ◽  
Regional Renal Blood Flow

Determination of Low Blood Flow Limits for Arteriovenous Carbon Dioxide Removal

ASAIO Journal ◽  
1996 ◽  
Vol 42 (5) ◽  
pp. M845-849 ◽  
Author(s):  
ROBERT L. BRUNSTON ◽  
WEIKE TAO ◽  
AKHIL BIDANI ◽  
VICTOR J. CARDENAS ◽  
DANIEL L. TRABER ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Carbon Dioxide Removal
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