scholarly journals Statistical Approaches Based on Deep Learning Regression for Verification of Normality of Blood Pressure Estimates

Sensors ◽  
2019 ◽  
Vol 19 (9) ◽  
pp. 2137 ◽  
Author(s):  
Soojeong Lee ◽  
Gangseong Lee ◽  
Gwanggil Jeon

Oscillometric blood pressure (BP) monitors currently estimate a single point but do not identify variations in response to physiological characteristics. In this paper, to analyze BP’s normality based on oscillometric measurements, we use statistical approaches including kurtosis, skewness, Kolmogorov-Smirnov, and correlation tests. Then, to mitigate uncertainties, we use a deep learning method to determine the confidence limits (CLs) of BP measurements based on their normality. The proposed deep learning regression model decreases the standard deviation of error (SDE) of the mean error and the mean absolute error and reduces the uncertainties of the CLs and SDEs of the proposed technique. We validate the normality of the distribution of the BP estimation which fits the standard normal distribution very well. We use a rank test in the deep learning technique to demonstrate the independence of the artificial systolic BP and diastolic BP estimations. We perform statistical tests to verify the normality of the BP measurements for individual subjects. The proposed methodology provides accurate BP estimations and reduces the uncertainties associated with the CLs and SDEs using the deep learning algorithm.

Author(s):  
Soojeong Lee ◽  
Joon-Hyuk Chang

Oscillometric blood pressure (BP) devices currently estimate a single point but do not identify fluctuations in BP or distinguish them from variations in response to physiological properties. In this paper, to analyze BP normality based on oscillometric measurements, we use statistical approaches including kurtosis, skewness, Kolmogorov-Smirnov, and correlation tests. Then, to mitigate uncertainties, we use a deep neural network (DNN) to determine the confidence limits (CLs) of BP measurements based on their normality. The proposed DNN regression model decreases the standard deviation of error (SDE) of the mean error (ME) and the mean absolute error (MAE) and reduces the uncertainty of the CLs and SDEs of the proposed technique. We validate the normality of the distribution of the BP estimation distribution which fits the Gaussian distribution very well. We use a rank test in the DNN regression model to demonstrate the independence of the artificial SBP and DBP estimations. First, we perform statistical tests to verify the normality of the BP measurements for individual subjects. The proposed methodology provides accurate BP estimations and reduces the uncertainties associated with the CLs and SDEs based on the DNN regression estimator.


Horticulturae ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. 21
Author(s):  
Jizhang Wang ◽  
Zhiheng Gao ◽  
Yun Zhang ◽  
Jing Zhou ◽  
Jianzhi Wu ◽  
...  

In order to realize the real-time and accurate detection of potted flowers on benches, in this paper we propose a method based on the ZED 2 stereo camera and the YOLO V4-Tiny deep learning algorithm for potted flower detection and location. First, an automatic detection model of flowers was established based on the YOLO V4-Tiny convolutional neural network (CNN) model, and the center points on the pixel plane of the flowers were obtained according to the prediction box. Then, the real-time 3D point cloud information obtained by the ZED 2 camera was used to calculate the actual position of the flowers. The test results showed that the mean average precision (MAP) and recall rate of the training model was 89.72% and 80%, respectively, and the real-time average detection frame rate of the model deployed under Jetson TX2 was 16 FPS. The results of the occlusion experiment showed that when the canopy overlap ratio between the two flowers is more than 10%, the recognition accuracy will be affected. The mean absolute error of the flower center location based on 3D point cloud information of the ZED 2 camera was 18.1 mm, and the maximum locating error of the flower center was 25.8 mm under different light radiation conditions. The method in this paper establishes the relationship between the detection target of flowers and the actual spatial location, which has reference significance for the machinery and automatic management of potted flowers on benches.


2021 ◽  
Vol 53 (2) ◽  
Author(s):  
Sen Yang ◽  
Yaping Zhang ◽  
Siu-Yeung Cho ◽  
Ricardo Correia ◽  
Stephen P. Morgan

AbstractConventional blood pressure (BP) measurement methods have different drawbacks such as being invasive, cuff-based or requiring manual operations. There is significant interest in the development of non-invasive, cuff-less and continual BP measurement based on physiological measurement. However, in these methods, extracting features from signals is challenging in the presence of noise or signal distortion. When using machine learning, errors in feature extraction result in errors in BP estimation, therefore, this study explores the use of raw signals as a direct input to a deep learning model. To enable comparison with the traditional machine learning models which use features from the photoplethysmogram and electrocardiogram, a hybrid deep learning model that utilises both raw signals and physical characteristics (age, height, weight and gender) is developed. This hybrid model performs best in terms of both diastolic BP (DBP) and systolic BP (SBP) with the mean absolute error being 3.23 ± 4.75 mmHg and 4.43 ± 6.09 mmHg respectively. DBP and SBP meet the Grade A and Grade B performance requirements of the British Hypertension Society respectively.


Technologies ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 14
Author(s):  
James Dzisi Gadze ◽  
Akua Acheampomaa Bamfo-Asante ◽  
Justice Owusu Agyemang ◽  
Henry Nunoo-Mensah ◽  
Kwasi Adu-Boahen Opare

Software-Defined Networking (SDN) is a new paradigm that revolutionizes the idea of a software-driven network through the separation of control and data planes. It addresses the problems of traditional network architecture. Nevertheless, this brilliant architecture is exposed to several security threats, e.g., the distributed denial of service (DDoS) attack, which is hard to contain in such software-based networks. The concept of a centralized controller in SDN makes it a single point of attack as well as a single point of failure. In this paper, deep learning-based models, long-short term memory (LSTM) and convolutional neural network (CNN), are investigated. It illustrates their possibility and efficiency in being used in detecting and mitigating DDoS attack. The paper focuses on TCP, UDP, and ICMP flood attacks that target the controller. The performance of the models was evaluated based on the accuracy, recall, and true negative rate. We compared the performance of the deep learning models with classical machine learning models. We further provide details on the time taken to detect and mitigate the attack. Our results show that RNN LSTM is a viable deep learning algorithm that can be applied in the detection and mitigation of DDoS in the SDN controller. Our proposed model produced an accuracy of 89.63%, which outperformed linear-based models such as SVM (86.85%) and Naive Bayes (82.61%). Although KNN, which is a linear-based model, outperformed our proposed model (achieving an accuracy of 99.4%), our proposed model provides a good trade-off between precision and recall, which makes it suitable for DDoS classification. In addition, it was realized that the split ratio of the training and testing datasets can give different results in the performance of a deep learning algorithm used in a specific work. The model achieved the best performance when a split of 70/30 was used in comparison to 80/20 and 60/40 split ratios.


Drones ◽  
2021 ◽  
Vol 5 (3) ◽  
pp. 68
Author(s):  
Jiwei Fan ◽  
Xiaogang Yang ◽  
Ruitao Lu ◽  
Xueli Xie ◽  
Weipeng Li

Unmanned aerial vehicles (UAV) and related technologies have played an active role in the prevention and control of novel coronaviruses at home and abroad, especially in epidemic prevention, surveillance, and elimination. However, the existing UAVs have a single function, limited processing capacity, and poor interaction. To overcome these shortcomings, we designed an intelligent anti-epidemic patrol detection and warning flight system, which integrates UAV autonomous navigation, deep learning, intelligent voice, and other technologies. Based on the convolution neural network and deep learning technology, the system possesses a crowd density detection method and a face mask detection method, which can detect the position of dense crowds. Intelligent voice alarm technology was used to achieve an intelligent alarm system for abnormal situations, such as crowd-gathering areas and people without masks, and to carry out intelligent dissemination of epidemic prevention policies, which provides a powerful technical means for epidemic prevention and delaying their spread. To verify the superiority and feasibility of the system, high-precision online analysis was carried out for the crowd in the inspection area, and pedestrians’ faces were detected on the ground to identify whether they were wearing a mask. The experimental results show that the mean absolute error (MAE) of the crowd density detection was less than 8.4, and the mean average precision (mAP) of face mask detection was 61.42%. The system can provide convenient and accurate evaluation information for decision-makers and meets the requirements of real-time and accurate detection.


Sensors ◽  
2021 ◽  
Vol 21 (5) ◽  
pp. 1867
Author(s):  
Tasbiraha Athaya ◽  
Sunwoong Choi

Blood pressure (BP) monitoring has significant importance in the treatment of hypertension and different cardiovascular health diseases. As photoplethysmogram (PPG) signals can be recorded non-invasively, research has been highly conducted to measure BP using PPG recently. In this paper, we propose a U-net deep learning architecture that uses fingertip PPG signal as input to estimate arterial BP (ABP) waveform non-invasively. From this waveform, we have also measured systolic BP (SBP), diastolic BP (DBP), and mean arterial pressure (MAP). The proposed method was evaluated on a subset of 100 subjects from two publicly available databases: MIMIC and MIMIC-III. The predicted ABP waveforms correlated highly with the reference waveforms and we have obtained an average Pearson’s correlation coefficient of 0.993. The mean absolute error is 3.68 ± 4.42 mmHg for SBP, 1.97 ± 2.92 mmHg for DBP, and 2.17 ± 3.06 mmHg for MAP which satisfy the requirements of the Association for the Advancement of Medical Instrumentation (AAMI) standard and obtain grade A according to the British Hypertension Society (BHS) standard. The results show that the proposed method is an efficient process to estimate ABP waveform directly using fingertip PPG.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Ludi Wang ◽  
Wei Zhou ◽  
Ying Xing ◽  
Xiaoguang Zhou

The prevention, evaluation, and treatment of hypertension have attracted increasing attention in recent years. As photoplethysmography (PPG) technology has been widely applied to wearable sensors, the noninvasive estimation of blood pressure (BP) using the PPG method has received considerable interest. In this paper, a method for estimating systolic and diastolic BP based only on a PPG signal is developed. The multitaper method (MTM) is used for feature extraction, and an artificial neural network (ANN) is used for estimation. Compared with previous approaches, the proposed method obtains better accuracy; the mean absolute error is 4.02 ± 2.79 mmHg for systolic BP and 2.27 ± 1.82 mmHg for diastolic BP.


Sensors ◽  
2021 ◽  
Vol 21 (18) ◽  
pp. 6264
Author(s):  
Muammar Sadrawi ◽  
Yin-Tsong Lin ◽  
Chien-Hung Lin ◽  
Bhekumuzi Mathunjwa ◽  
Ho-Tsung Hsin ◽  
...  

This study evaluates cardiovascular and cerebral hemodynamics systems by only using non-invasive electrocardiography (ECG) signals. The Massachusetts General Hospital/Marquette Foundation (MGH/MF) and Cerebral Hemodynamic Autoregulatory Information System Database (CHARIS DB) from the PhysioNet database are used for cardiovascular and cerebral hemodynamics, respectively. For cardiovascular hemodynamics, the ECG is used for generating the arterial blood pressure (ABP), central venous pressure (CVP), and pulmonary arterial pressure (PAP). Meanwhile, for cerebral hemodynamics, the ECG is utilized for the intracranial pressure (ICP) generator. A deep convolutional autoencoder system is applied for this study. The cross-validation method with Pearson’s linear correlation (R), root mean squared error (RMSE), and mean absolute error (MAE) are measured for the evaluations. Initially, the ECG is used to generate the cardiovascular waveform. For the ABP system—the systolic blood pressure (SBP) and diastolic blood pressures (DBP)—the R evaluations are 0.894 ± 0.004 and 0.881 ± 0.005, respectively. The MAE evaluations for SBP and DBP are, respectively, 6.645 ± 0.353 mmHg and 3.210 ± 0.104 mmHg. Furthermore, for the PAP system—the systolic and diastolic pressures—the R evaluations are 0.864 ± 0.003 mmHg and 0.817 ± 0.006 mmHg, respectively. The MAE evaluations for systolic and diastolic pressures are, respectively, 3.847 ± 0.136 mmHg and 2.964 ± 0.181 mmHg. Meanwhile, the mean CVP evaluations are 0.916 ± 0.001, 2.220 ± 0.039 mmHg, and 1.329 ± 0.036 mmHg, respectively, for R, RMSE, and MAE. For the mean ICP evaluation in cerebral hemodynamics, the R and MAE evaluations are 0.914 ± 0.003 and 2.404 ± 0.043 mmHg, respectively. This study, as a proof of concept, concludes that the non-invasive cardiovascular and cerebral hemodynamics systems can be potentially investigated by only using the ECG signal.


Sensors ◽  
2021 ◽  
Vol 21 (21) ◽  
pp. 7207
Author(s):  
Zheming Li ◽  
Wei He

Compared with diastolic blood pressure (DBP) and systolic blood pressure (SBP), the blood pressure (BP) waveform contains richer physiological information that can be used for disease diagnosis. However, most models based on photoplethysmogram (PPG) signals can only estimate SBP and DBP and are susceptible to noise signals. We focus on estimating the BP waveform rather than discrete BP values. We propose a model based on a generalized regression neural network to estimate the BP waveform, SBP and DBP. This model takes the raw PPG signal as input and BP waveform as output. The SBP and DBP are extracted from the estimated BP waveform. In addition, the model contains encoders and decoders, and their role is to be responsible for the conversion between the time domain and frequency domain of the waveform. The prediction results of our model show that the mean absolute error is 3.96 ± 5.36 mmHg for SBP and 2.39 ± 3.28 mmHg for DBP, the root mean square error is 5.54 for SBP and 3.45 for DBP. These results fulfill the Association for the Advancement of Medical Instrumentation (AAMI) standard and obtain grade A according to the British Hypertension Society (BHS) standard. The results show that the proposed model can effectively estimate the BP waveform only using the raw PPG signal.


2019 ◽  
Vol 8 (2) ◽  
pp. 145
Author(s):  
Agus Susilawati

Hypertension is a condition where a person experiences an increase in blood pressure above normal which is indicated by a figure of 140 mmHg systolic and 90 mmHg diastolic. One of the management of non-pharmacological hypertension is the therapy of murottal Al-Qur'an Surah Ar-Rahman. This study aimed to determine the effect of therapeutic Murottal Al-Qur'an Surah Ar-Rahman toward decreased blood pressure in elderly hypertensive patients in PSTW  Budi Luhur Jambi City. This study was conducted on April 9th-20th 2019 with total samples were 16 people. Sample used purposive sampling technique. The instrument used sphygmomanometer digital and observation sheet. After being given the intervention of therapeutic Murottal Al-Qur’an, the mean value of systole blood pressure was obtained 157 mmHg, on the statistical test was obtained score p-value 0,000 (˂0,05), the mean value of diastole blood pressure after intervention is 88,19 mmHg, on the statistical tests was obtained score p-value 0,000 (˂0,05) it means there is the effect of therapeutic Murottal Al-Qur'an Surah Ar-Rahman toward decreased  blood pressure in elderly hypertensive patients in PSTW Budi Luhur Jambi City. It is conclused that respondents who were given therapeutic murottal Al-Qur'an experienced a decrease in blood pressure. It is expected to PSTW Budi Luhur Jambi City to applying non-pharmacological therapies such as the therapeutic Murottal Al-Qur'an Surah Ar-Rahman to reduce blood pressure in elderly people with hypertension.


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