scholarly journals Support-Material-Free Microfluidics on an Electrochemical Sensors Platform by Aerosol Jet Printing

Sensors ◽  
2019 ◽  
Vol 19 (8) ◽  
pp. 1842 ◽  
Author(s):  
Nicolò Giuseppe Di Novo ◽  
Edoardo Cantù ◽  
Sarah Tonello ◽  
Emilio Sardini ◽  
Mauro Serpelloni
Keyword(s):  
Electrochemical Sensors ◽  
Printed Electronics ◽  
Limit Of Detection ◽  
Support Material ◽  
Uv Curable ◽  
Sensor Platform ◽  
Relative Standard ◽  
Wide Range ◽  
Jet Printing ◽  
Aerosol Jet Printing

Printed electronics have led to new possibilities in the detection and quantification of a wide range of molecules important for medical, biotechnological, and environmental fields. The integration with microfluidics is often adopted to avoid hand-deposition of little volumes of reagents and samples on miniaturized electrodes that strongly depend on operator’s skills. Here we report design, fabrication and test of an easy-to-use electrochemical sensor platform with microfluidics entirely realized with Aerosol Jet Printing (AJP). We printed a six-electrochemical-sensors platform with AJP and we explored the possibility to aerosol jet print directly on it a microfluidic structure without any support material. Thus, the sacrificial material removal and/or the assembly with sensors steps are avoided. The repeatability observed when printing both conductive and ultraviolet (UV)-curable polymer inks can be supported from the values of relative standard deviation of maximum 5% for thickness and 9% for line width. We designed the whole microfluidic platform to make the sample deposition (20 μL) independent from the operator. To validate the platform, we quantified glucose at different concentrations using a standard enzyme-mediated procedure. Both mediator and enzyme were directly aerosol jet printed on working electrodes (WEs), thus the proposed platform is entirely fabricated by AJP and ready to use. The chronoamperometric tests show limit of detection (LOD) = 2.4 mM and sensitivity = 2.2 ± 0.08 µA/mM confirming the effectiveness of mediator and enzyme directly aerosol jet printed to provide sensing in a clinically relevant range (3–10 mM). The average relative standard inter-platform deviation is about 8%. AJP technique can be used for fabricating a ready-to-use microfluidic device that does not need further processing after fabrication, but is promptly available for electrochemical sample analysis.

scholarly journals A Sparse Representation Classification Approach for Near Real-Time, Physics-Based Functional Monitoring of Aerosol Jet-Fabricated Electronics

2020 ◽  
Vol 142 (8) ◽  
Author(s):  
Roozbeh (Ross) Salary ◽  
Jack P. Lombardi ◽  
Darshana L. Weerawarne ◽  
M. Samie Tootooni ◽  
Prahalada K. Rao ◽  
...  
Keyword(s):  
Sparse Representation ◽  
Real Time ◽  
Functional Properties ◽  
Printed Electronics ◽  
Imaging System ◽  
Monitoring And Control ◽  
Wide Range ◽  
Sparse Representation Classification ◽  
Aerosol Jet Printing

Abstract Aerosol jet printing (AJP) is a direct-write additive manufacturing (AM) method, emerging as the process of choice for the fabrication of a broad spectrum of electronics, such as sensors, transistors, and optoelectronic devices. However, AJP is a highly complex process, prone to intrinsic gradual drifts. Consequently, real-time process monitoring and control in AJP is a bourgeoning need. The goal of this work is to establish an integrated, smart platform for in situ and real-time monitoring of the functional properties of AJ-printed electronics. In pursuit of this goal, the objective is to forward a multiple-input, single-output (MISO) intelligent learning model—based on sparse representation classification (SRC)—to estimate the functional properties (e.g., resistance) in situ as well as in real-time. The aim is to classify the resistance of printed electronic traces (lines) as a function of AJP process parameters and the trace morphology characteristics (e.g., line width, thickness, and cross-sectional area (CSA)). To realize this objective, line morphology is captured using a series of images, acquired: (i) in situ via an integrated high-resolution imaging system and (ii) in real-time via the AJP standard process monitor camera. Utilizing image processing algorithms developed in-house, a wide range of 2D and 3D morphology features are extracted, constituting the primary source of data for the training, validation, and testing of the SRC model. The four-point probe method (also known as Kelvin sensing) is used to measure the resistance of the deposited traces and as a result, to define a priori class labels. The results of this study exhibited that using the presented approach, the resistance (and potentially, other functional properties) of printed electronics can be estimated both in situ and in real-time with an accuracy of ≥ 90%.

scholarly journals Application of biosynthesized metal nanoparticles in electrochemical sensors

2021 ◽  
pp. 77-77
Author(s):  
Totka Dodevska ◽  
Dobrin Hadzhiev ◽  
Ivan Shterev ◽  
Yanna Lazarova
Keyword(s):  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Electrochemical Sensors ◽  
Dynamic Range ◽  
Limit Of Detection ◽  
Cost Effective ◽  
Electrochemical Sensing ◽  
Synthesis Methods ◽  
Range Limit ◽  
Wide Range

Recently, the development of eco-friendly, cost-effective and reliable methods for synthesis of metal nanoparticles has drawn a considerable attention. The so-called green synthesis, using mild reaction conditions and natural resources as plant extracts and microorganisms, has established as a convenient, sustainable, cheap and environmentally safe approach for synthesis of a wide range of nanomaterials. Over the past decade, biosynthesis is regarded as an important tool for reducing the harmful effects of traditional nanoparticle synthesis methods commonly used in laboratories and industry. This review emphasizes the significance of biosynthesized metal nanoparticles in the field of electrochemical sensing. There is increasing evidence that green synthesis of nanoparticles provides a new direction in designing of cost-effective, highly sensitive and selective electrode-catalysts applicable in food, clinical and environmental analysis. The article is based on 157 references and provided a detailed overview on the main approaches for green synthesis of metal nanoparticles and their applications in designing of electrochemical sensor devices. Important operational characteristics including sensitivity, dynamic range, limit of detection, as well as data on stability and reproducibility of sensors have also been covered. Keywords: biosynthesis; green synthesis; nanomaterials; nanotechnology; modified electrodes

Preparation of High-Solids UV-Curable Actylate Pressure-Sensitive Adhesive with Low Viscosity for Printed Electronics

2014 ◽  
Vol 644-650 ◽  
pp. 4936-4940
Author(s):  
Yan Yan Cui ◽  
Guang Xue Chen
Keyword(s):  
Printed Electronics ◽  
High Solids ◽  
Pressure Sensitive Adhesive ◽  
Uv Curable ◽  
Ink Jet Printing ◽  
Pressure Sensitive Adhesives ◽  
Low Viscosity ◽  
Pressure Sensitive ◽  
Ink Jet ◽  
Jet Printing

If the pressure sensitive adhesive is coated on the back, it can be used for bonding electronic tag, overburden, protective layer, and RFID layer. The acrylate pressure sensitive adhesives are simple and less pollution, so more and more companies pay attention on this kind of binder. Since the thickness of adhesive layer is relatively small, ink-jet printing is now widely used to easily obtain thin layer and design the pressure sensitive adhesive shape of different parts. So how to get superior performance pressure sensitive adhesive which is suitable for ink-jet printing become an urgent problem in printed electronics. The experiment was conducted through solution copolymerization of various vinyl monomers which were selected on the principle of solvent parameter prepared by free radical polymerization. The monomer, initiator mixture solution was dropped in continuous and synchronization process. By regulating the amount of initiator and polymerization temperature, we could effectively reduce the system viscosity and prepare high quality high-solids acrylate UV-curable pressure sensitive adhesives with low viscosity for ink-jet printing. The influence of initiator, solvents, transfer reagents and temperature on the structure and properties of the resin were discussed.

Quality Modeling of Printed Electronics in Aerosol Jet Printing Based on Microscopic Images

2017 ◽  
Vol 139 (7) ◽  
Author(s):  
Hongyue Sun ◽  
Kan Wang ◽  
Yifu Li ◽  
Chuck Zhang ◽  
Ran Jin
Keyword(s):  
Printed Circuit Boards ◽  
Printed Electronics ◽  
Model Performance ◽  
Image Features ◽  
Direct Write ◽  
Microscopic Images ◽  
Jet Printing ◽  
Manufacturing Techniques ◽  
Input Variables ◽  
Aerosol Jet Printing

Aerosol jet printing (AJP) is a direct write technology that enables fabrication of flexible, fine scale printed electronics on conformal substrates. AJP does not require the time consuming mask and postpatterning processes compared with traditional electronics manufacturing techniques. Thus, the cycle time can be dramatically reduced, and highly personalized designs of electronics can be realized. AJP has been successfully applied to a variety of industries, with different combinations of inks and substrates. However, the quality of the printed electronics, such as resistance, is not able to be measured online. On the other hand, the microscopic image sensors are widely used for printed circuit boards (PCBs) quality quantification and inspection. In this paper, two widely used quality variables of printed electronics, resistance and overspray, will be jointly modeled based on microscopic images for fast quality assessment. Augmented quantitative and qualitative (AUGQQ) models are proposed to use features of microscopic images taken at different locations on the printed electronics as input variables, and resistance and overspray as output variables. The association of resistance and overspray can be investigated through the AUGQQ models formulation. A case study for fabricating silver lines with Optomec® aerosol jet system is used to evaluate the model performance. The proposed AUGQQ models can help assess the printed electronics quality and identify important image features in a timely manner.

scholarly journals Magnetic and Mesoporous Silica-Niobia Material as Modifier of Carbon Paste Electrode for p-Nitrophenol Electrochemical Determination

2021 ◽  
Author(s):  
Oleg Tkachenko ◽  
Danielle da Rosa ◽  
Anike Virgili ◽  
Marcos Vasconcellos ◽  
Tania Costa ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Carbon Paste Electrode ◽  
Electrochemical Sensors ◽  
Limit Of Detection ◽  
Sol Gel ◽  
Synthesis Method ◽  
Differential Pulse ◽  
Carbon Paste ◽  
Wide Range ◽  
Paste Electrode

In the present work, the sol-gel synthesis method was employed as strategy to obtain a magnetic and mesoporous silica-niobia material. The planned synthesis was based on the heterocondensation of niobium and silicon alkoxide precursors, in the presence of spherical magnetite particles. The resulting material presented interesting characteristics such as magnetism, large mesopores, in the range from 20 to 50 nm, and 68 m2 g−1 of surface area. These features allowed its use as modifier of carbon paste electrode for p-nitrophenol determination, since niobia has never been used in electrochemical sensors for the determination of nitrophenol compounds. By using differential pulse voltammetry technique, the electrode can be applied in a wide range of p-nitrophenol concentration, from 10 to 490 μmol L−1, with a limit of detection of 1.2 µmol L−1 and sensitivity up to 0.60 µA L µmol−1. The proposed electrode presented good sensitivity and selectivity and it was applied in real water samples.

scholarly journals Printed Smart Devices on Cellulose-Based Materials by means of Aerosol-Jet Printing and Photonic Curing

Sensors ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 841 ◽  
Author(s):  
Mauro Serpelloni ◽  
Edoardo Cantù ◽  
Michela Borghetti ◽  
Emilio Sardini
Keyword(s):  
Printed Electronics ◽  
Optical Microscope ◽  
Research Field ◽  
Smart Devices ◽  
Chromatographic Paper ◽  
Cellulose Substrates ◽  
Photonic Curing ◽  
Jet Printing ◽  
High Flexibility ◽  
Aerosol Jet Printing

Printed electronics is an expanding research field that can reach the goal of reducing the environmental impact on electronics exploiting renewable and biodegradable materials, like paper. In our work, we designed and tested a new method for fabricating hybrid smart devices on cellulose substrates by aerosol jet printing (AJP) and photonic curing, also known as flash lamp annealing (FLA), capable to cure low temperature materials without any damage. Three different cellulose-based materials (chromatographic paper, photopaper, cardboard) were tested. Multilayer capability and SMDs (surface mount devices) interconnections are possible permitting high flexibility in the fabrication process. Electrical and geometrical tests were performed to analyze the behavior of printed samples. Resulted resistivities are 26.3 × 10−8 Ω⋅m on chromatographic paper, 22.3 × 10−8 Ω⋅m on photopaper and 13.1 × 10−8 Ω⋅m on cardboard. Profilometer and optical microscope evaluations were performed to state deposition quality and penetration of the ink in cellulose materials (thicknesses equal to 24.9, 28.5, and 51 μm respectively for chromatographic paper, photopaper, and cardboard). Furthermore, bending (only chromatographic paper did not reach the break-up) and damp environment tests (no significant variations in resistance) where performed. A final prototype of a complete functioning multilayer smart devices on cellulose 3D-substrate is shown, characterized by multilayers, capacitive sensors, SMDs interconnections.

Hybrid UV laser direct writing of UV-curable PDMS thin film using aerosol jet printing

2019 ◽  
Vol 125 (2) ◽  
Author(s):  
Arndt Hohnholz ◽  
Kotaro Obata ◽  
Yasutaka Nakajima ◽  
Jürgen Koch ◽  
Mitsuhiro Terakawa ◽  
...  
Keyword(s):  
Thin Film ◽  
Direct Writing ◽  
Uv Laser ◽  
Laser Direct Writing ◽  
Uv Curable ◽  
Jet Printing ◽  
Aerosol Jet Printing

scholarly journals Determination of Gliclazide in Pharmaceutical Preparations by Capillary Gas Chromatography with Cool On-Column Injection and Elimination of the Matrix Effect

2001 ◽  
Vol 84 (6) ◽  
pp. 1695-1702 ◽  
Author(s):  
Jan Krzek ◽  
Janusz Czekaj ◽  
Maria Moniczewska ◽  
Włodzimierz Rzeszutko
Keyword(s):  
Gas Chromatography ◽  
Capillary Gas Chromatography ◽  
Limit Of Detection ◽  
Internal Standard ◽  
Pharmaceutical Preparations ◽  
Fused Silica ◽  
Uv Spectrophotometry ◽  
Relative Standard ◽  
Wide Range ◽  
The Matrix

Abstract Conditions were established for the identification and quantitation of gliclazide in pharmaceutical preparations by capillary gas chromatography with flame ionization detection and cool on-column injection. Gliclazide was extracted with methanol and, after filtration, assayed on a (25 m × 0.25 mm id, 0.2 μm film thickness) CP-WAX 58 (FFAP)–CB WCOT fused silica column. Because the available preparations were of various origins and, therefore, could differ in auxiliary substances and their qualitative parameters, the influence of the matrix constituents on the analytical results was taken into account. Good separation conditions were established for the developed method. The retention time of gliclazide is about 36 min and differs from the retention times of the internal standard (approximately 29 min) and additional peaks present in chromatograms (20–26 min), which were assigned to matrix constituents. The recoveries of gliclozide were high and reached 96.5%. The developed method is characterized by selectivity and precision (relative standard deviation 0.38–1.26%), a wide range of linearity (0.1–10.0 mg/mL), and a limit of detection of 30 ng. In addition, the results of chromatographic analyses calculated in 3 ways were compared with those obtained by UV spectrophotometry. The suggested technique of cool on-column injection, in contrast with split-splitless injection (used in preliminary investigations), reduces to a minimum the possibility of thermal decomposition of gliclazide.

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