scholarly journals Multiplexed Paper Microfluidics for Titration and Detection of Ingredients in Beverages

Sensors ◽  
2019 ◽  
Vol 19 (6) ◽  
pp. 1286 ◽  
Author(s):  
Alisha Prasad ◽  
Tiffany Tran ◽  
Manas Gartia
Keyword(s):  
Food Safety ◽  
Low Cost ◽  
Fruit Juices ◽  
Analytical Tool ◽  
Food Spoilage ◽  
Paper Microfluidics ◽  
Biochemical Component ◽  
Paper Microfluidic ◽  
Safety Applications ◽  
Titration Study

Food safety and access to systematic approaches for ensuring detection of food hazards is an important issue in most developing countries. With the arrival of paper-based analytical devices (µPADs) as a promising, rapid, easy-to-use, and low-cost analytical tool, we demonstrated a simple microfluidic-based titration study for the analysis of packaged fruit juices. Similar, to the titration experiments using traditional glassware in chemistry laboratories, in this study the titration experiments were developed using paper microfluidics for the analysis of several analytes such as pH, vitamin C, sugars, and preservatives present in the packaged fruit juices. The allergen found commonly in dairy based mixtures and the non-pathogenic biochemical component responsible for food spoilage in cider based fruit juices were also determined. The results obtained using paper microfluidics were compared with those obtained using a conventional spectrophotometric technique. Finally, a paper microfluidics based multiplexed sensor was developed for the analysis of common nutritional ingredients, an allergen, and a non-pathogenic byproduct present in packaged fruit juices on a single platform. Overall, the results presented in this study reveal that the proposed paper microfluidic assisted colorimetric multiplexed sensor offers a quick and reliable tool for on-spot routine analysis for food safety applications.

The use of NIRS in the dairy industry: New trends and applications

NIR news ◽  
2017 ◽  
Vol 28 (8) ◽  
pp. 22-25 ◽  
Author(s):  
SE Holroyd
Keyword(s):  
Infrared Spectroscopy ◽  
Food Safety ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Dairy Industry ◽  
Analytical Tool ◽  
Safety Applications ◽  
Over Time

Near infrared spectroscopy has been widely used as an analytical tool in the dairy industry since the 1980s. NIR use has progressed as instruments have evolved over time. Today there are fleets of networked instruments using generic calibrations across broad product classes for at- and in-line applications. More recently NIR has found application for food safety applications as well, increasingly using non-targeted approaches. However the relevant strengths and weaknesses of NIR must be thoroughly understood in these challenging applications.

scholarly journals Simplified Approach to Predict Food Safety through the Maximum Specific Bacterial Growth Rate as Function of Extrinsic and Intrinsic Parameters

2021 ◽  
Vol 5 (2) ◽  
pp. 22
Author(s):  
Pedro D. Gaspar ◽  
Joel Alves ◽  
Pedro Pinto
Keyword(s):  
Growth Rate ◽  
Food Safety ◽  
Information And Communication Technologies ◽  
Bacterial Growth ◽  
Low Cost ◽  
Extrinsic Factors ◽  
Bacterial Growth Rate ◽  
Modeling Tools ◽  
Simplified Approach ◽  
Food Safety And Quality

Currently, we assist the emergence of sensors and low-cost information and communication technologies applied to food products, in order to improve food safety and quality along the food chain. Thus, it is relevant to implement predictive mathematical modeling tools in order to predict changes in the food quality and allow decision-making for expiration dates. To perform that, the Baranyi and Roberts model and the online tool Combined Database for Predictive Microbiology (Combase) were used to determine the factors that define the growth of different bacteria. These factors applied to the equation that determines the maximum specific growth rate establish a relation between the bacterial growth and the intrinsic and extrinsic factors that define the bacteria environment. These models may be programmed in low-cost wireless biochemical sensor devices applied to packaging and food supply chains to promote food safety and quality through real time traceability.

scholarly journals Molecularly Imprinted Polymers Combined with Electrochemical Sensors for Food Contaminants Analysis

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4607
Author(s):  
Dounia Elfadil ◽  
Abderrahman Lamaoui ◽  
Flavio Della Pelle ◽  
Aziz Amine ◽  
Dario Compagnone
Keyword(s):  
Food Safety ◽  
Molecularly Imprinted Polymers ◽  
Electrochemical Sensors ◽  
Low Cost ◽  
Electrochemical Analysis ◽  
Ease Of Use ◽  
Electrochemical Sensing ◽  
Food Contaminants ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Detection of relevant contaminants using screening approaches is a key issue to ensure food safety and respect for the regulatory limits established. Electrochemical sensors present several advantages such as rapidity; ease of use; possibility of on-site analysis and low cost. The lack of selectivity for electrochemical sensors working in complex samples as food may be overcome by coupling them with molecularly imprinted polymers (MIPs). MIPs are synthetic materials that mimic biological receptors and are produced by the polymerization of functional monomers in presence of a target analyte. This paper critically reviews and discusses the recent progress in MIP-based electrochemical sensors for food safety. A brief introduction on MIPs and electrochemical sensors is given; followed by a discussion of the recent achievements for various MIPs-based electrochemical sensors for food contaminants analysis. Both electropolymerization and chemical synthesis of MIP-based electrochemical sensing are discussed as well as the relevant applications of MIPs used in sample preparation and then coupled to electrochemical analysis. Future perspectives and challenges have been eventually given.

Raman spectroscopy and imaging to detect contaminants for food safety applications

2013 ◽  
Author(s):  
Kuanglin Chao ◽  
Jianwei Qin ◽  
Moon S. Kim ◽  
Yankun Peng ◽  
Diane Chan ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Food Safety ◽  
Safety Applications

Monitoring soil nutrients using a simple cafetiere-based extraction with paper-based readout. 

2021 ◽  
Author(s):  
Samantha Richardson ◽  
Samira Al Hinai ◽  
Jesse Gitaka ◽  
Will Mayes ◽  
Mark Lorch ◽  
...  
Keyword(s):  
Image Analysis ◽  
Incubation Period ◽  
Soil Nutrients ◽  
Agricultural Land ◽  
Low Cost ◽  
Smart Phone ◽  
Water Volume ◽  
Readout System ◽  
Paper Microfluidic ◽  
Nutrient Extraction

<p>Routine monitoring of available soil nutrients is required to better manage agricultural land<sup>1</sup>, especially in many lower and middle income countries (LMICs). Analysis often still relies on laboratory-based equipment, meaning regular monitoring is challenging.<sup>2</sup> The limited number of in situ sensors that exist are expensive or have complex workflows, thus are not suitable in LMICs, where the need is greatest.<sup>3</sup> We aim to develop a simple-to-use, low-cost analysis system that enable farmers to directly monitor available nutrients and pH on-site, thus making informed decisions about when and where to apply fertilisers.</p><p>We combine nutrient extraction via a cafetiere-based filtration system with nutrient readout on a paper microfluidic analysis device (PAD) employing colour producing reactions that can be captured via a smartphone camera through an app. Image analysis of colour intensity permits quantitation of analytes. We initially focus on key nutrients (phosphate, nitrate) and pH analysis.</p><p>For extraction of phosphate, we mixed soil and water in the cafetiere and quantified the extracted phosphate via phosphomolybdenum blue chemistry. For example, for 5 g of soil, a water volume of about 160 mL led to optimum extraction. Active mixing, by pushing coffee filter plunger up and down, aided extraction. A mixing period of 3 min yielded maximum extraction; this time period was deemed suitable for an on-site workflow.</p><p>Following nutrient extraction, a simple-to-use readout system is required. For this, we developed colourimetric paper-based microfluidic devices; these are simply dipped into the decanted soil supernatant from the cafetiere and wick fluids based on capillary forces. Chemical reagents are pre-stored in reaction zones, created by patterning cellulose with wax barriers. Our devices contain multiple paper layers with different reagents; these are folded, laminated and holes cut for sample entry. Following the required incubation time, the developed colour is captured using a smartphone. This constitutes a portable detector, already available to envisaged end users, even in LMICs. We have previously developed an on-paper reaction for monitoring phosphates in fresh water in the mg L<sup>-1</sup> working range, with readout after an incubation period of 3 min. This method was adapted here to enable storage at ambient temperatures up to 1 week by incorporating additional acidic reagents. Further pad devices were developed in our group for colour-based readout of nitrate, involving a two-step reaction chemistry. Within a relatively short incubation period (≤8 min) a pink coloured was formed following reduction of nitrate to nitrite with zinc and subsequent reaction to form an azo-dye. This system achieved detection in the low mg L<sup>-1</sup> range. Moreover, a pad to monitor pH was developed, employing chlorophenol red indicator, with linear response achieved over the relevant pH 5-7 range.  </p><p>Our analysis workflow combines a simple-to-use cafetiere-based extraction method with paper microfluidic colour readout and smart-phone detector. This has the potential to enable farmers to monitor nutrients in soils on-site. Future work will aim at integrating multiple analytes into a single analysis card and to automate image analysis.</p><p>[1] <em>Europ. J. Agronomy</em>, 55, 42–52, <strong>2014.</strong></p><p>[2] <em>Nutr. Cycling Agroecosyst.,</em> 109, 77-102, <strong>2017.</strong></p><p>[3] Sens Actuators B, 30, 126855, <strong>2019.</strong></p>

scholarly journals Nucleic acid-based biosensors: analytical devices for prevention, diagnosis and treatment of diseases

Revista Vitae ◽  
2021 ◽  
Vol 28 (3) ◽  
Author(s):  
Laura Carvajal Barbosa ◽  
Diego Insuasty Cepeda ◽  
Andrés Felipe León Torres ◽  
Maria Mercedes Arias Cortes ◽  
Zuly Jenny Rivera Monroy ◽  
...  
Keyword(s):  
Food Safety ◽  
Nucleic Acid ◽  
Nucleic Acids ◽  
Pathogenic Bacteria ◽  
High Selectivity ◽  
Low Cost ◽  
Analytical Techniques ◽  
High Sensitivity ◽  
Disease Status ◽  
Public Health Issue

BACKGROUND : Biosensing techniques have been the subject of exponentially increasing interest due to their performance advantages such as high selectivity and sensitivity, easy operation, low cost, short analysis time, simple sample preparation, and real-time detection. Biosensors have been developed by integrating the unique specificity of biological reactions and the high sensitivity of physical sensors. Therefore, there has been a broad scope of applications for biosensing techniques, and nowadays, they are ubiquitous in different areas of environmental, healthcare, and food safety. Biosensors have been used for environmental studies, detecting and quantifying pollutants in water, air, and soil. Biosensors also showed great potential for developing analytical tools with countless applications in diagnosing, preventing, and treating diseases, mainly by detecting biomarkers. Biosensors as a medical device can identify nucleic acids, proteins, peptides, metabolites, etc.; these analytes may be biomarkers associated with the disease status. Bacterial food contamination is considered a worldwide public health issue; biosensor-based analytical techniques can identify the presence or absence of pathogenic agents in food. OBJECTIVES: The present review aims to establish state-of-the-art, comprising the recent advances in the use of nucleic acid-based biosensors and their novel application for the detection of nucleic acids. Emphasis will be given to the performance characteristics, advantages, and challenges. Additionally, food safety applications of nucleic acid-based biosensors will be discussed. METHODS: Recent research articles related to nucleic acid-based biosensors, biosensors for detecting nucleic acids, biosensors and food safety, and biosensors in environmental monitoring were reviewed. Also, biosensing platforms associated with the clinical diagnosis and food industry were included. RESULTS: It is possible to appreciate that multiple applications of nucleic acid-based biosensors have been reported in the diagnosis, prevention, and treatment of diseases, as well as to identify foodborne pathogenic bacteria. The use of PNA and aptamers opens the possibility of developing new biometric tools with better analytical properties. CONCLUSIONS: Biosensors could be considered the most important tool for preventing, treating, and monitoring diseases that significantly impact human health. The aptamers have advantages as biorecognition elements due to the structural conformation, hybridization capacity, robustness, stability, and lower costs. It is necessary to implement biosensors in situ to identify analytes with high selectivity and lower detection limits.

Immunoassays in Food Safety Applications

1989 ◽  
pp. 38-50 ◽  
Author(s):  
Albert E. Pohland ◽  
Mary W. Trucksess ◽  
Samuel W. Page
Keyword(s):  
Food Safety ◽  
Safety Applications

Cold Plasma Hurdled Strategies for Food Safety Applications

2021 ◽  
pp. 325-340
Author(s):  
Xinyu Liao ◽  
Yue Zhang ◽  
Xihong Zhao ◽  
Tian Ding
Keyword(s):  
Food Safety ◽  
Cold Plasma ◽  
Safety Applications

scholarly journals Using printer ink color to control the behavior of paper microfluidics

Lab on a Chip ◽  
2019 ◽  
Vol 19 (11) ◽  
pp. 2000-2008 ◽  
Author(s):  
Joshua Potter ◽  
Philip Brisk ◽  
William H. Grover
Keyword(s):  
Microfluidic Devices ◽  
Paper Microfluidics ◽  
Paper Microfluidic

Different colors of wax inks behave differently in paper microfluidic devices, enabling the development of new color-based paper microfluidic components.

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