scholarly journals Node Immunization with Time-Sensitive Restrictions

Sensors ◽  
2016 ◽  
Vol 16 (12) ◽  
pp. 2141 ◽  
Author(s):  
Wen Cui ◽  
Xiaoqing Gong ◽  
Chen Liu ◽  
Dan Xu ◽  
Xiaojiang Chen ◽  
...  
Keyword(s):  
Vaccine ◽  
2001 ◽  
Vol 20 (1-2) ◽  
pp. 49-58 ◽  
Author(s):  
Susan Finerty ◽  
Christopher R Stokes ◽  
Timothy J Gruffydd-Jones ◽  
Timothy J Hillman ◽  
Frances J Barr ◽  
...  

1999 ◽  
Vol 73 (12) ◽  
pp. 10214-10223 ◽  
Author(s):  
P. J. Lewis ◽  
S. van Drunen Littel-van den Hurk ◽  
L. A. Babiuk

ABSTRACT The potential for DNA vaccines encoding mutated versions of the same antigen to modulate immune responses in C3H/HeN mice was investigated. We created expression plasmids that encoded several versions of glycoprotein D (gD) from bovine herpesvirus 1, including authentic membrane-anchored glycoprotein (pSLRSV.AgD), a secreted glycoprotein (pSLRSV.SgD), and an intracellular protein (pSLRSV.CgD). Immunization of an inbred strain of mice with these plasmids resulted in highly efficacious and long-lasting humoral and cell-mediated immunity. We also demonstrated that the cell compartment in which plasmid-encoded gD was expressed caused a deviation in the serum immunoglobulin (Ig) isotype profile as well as the predominant cytokines secreted from the draining lymph node. Immunization of C3H/HeN mice with DNA vaccines encoding cell-associated forms of gD resulted in a predominance of serum IgG2a and gamma interferon-secreting cells within the spleens and draining lymph nodes. In contrast, mice immunized with a secreted form of this same antigen displayed immune responses characterized by greater levels of interleukin 4 in the draining lymph node and IgG1 as the predominant serum isotype. We also showed evidence of compartmentalization of distinct immune responses within different lymphoid organs.


2014 ◽  
Vol 926-930 ◽  
pp. 1993-1996
Author(s):  
Dong Yan Zhao ◽  
Xiang Lou Liu ◽  
Dong Xue Wang ◽  
Hai Wei Mu ◽  
Hong Mei Song ◽  
...  

The immunization algorithm is from the theory of complex network. The algorithm is simple, highly feasible based on scale-free network model. This paper uses random immunization algorithm to solve optical network energy issues. This paper selects the service to be the operator and to save energy through node immunization. The simulation results show the algorithm can be implemented. This paper provides another possibility to energy saving on optical network.


1996 ◽  
Vol 2 (7) ◽  
pp. 767-775 ◽  
Author(s):  
Thomas Lehner ◽  
Yufei Wang ◽  
Martin Cranage ◽  
Lesley A. Bergmeier ◽  
Elaine Mitchell ◽  
...  

2016 ◽  
Vol 28 (1) ◽  
pp. 113-126 ◽  
Author(s):  
Chen Chen ◽  
Hanghang Tong ◽  
B. Aditya Prakash ◽  
Charalampos E. Tsourakakis ◽  
Tina Eliassi-Rad ◽  
...  

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