scholarly journals Rapidly Growing Aneurysm with Ulcer-like Projection Complicated with Bacteroides ovatus Bacteremia

Reports ◽  
2021 ◽  
Vol 4 (3) ◽  
pp. 28
Author(s):  
Masayoshi Kusunoki ◽  
Ryuichi Ohta ◽  
Jumpei Sawa ◽  
Chiaki Sano
Keyword(s):  
Antibiotic Resistance ◽  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Thoracic Aortic Aneurysm ◽  
Drug Resistant ◽  
Surgical Drainage ◽  
Antibiotic Selection ◽  
The Past ◽  
Bacteroides Ovatus ◽  
Ulcerative Lesions

The incidence of anaerobic bacteremia has been increasing over the past several decades. Further, antibiotic resistance in Bacteroides is a pertinent issue. A 76-year-old man was brought to our hospital with complaints of fever, chills, and abdominal pain. Empiric antibiotics induced minimal relief. The blood culture was positive for multi-drug resistant Bacteroides ovatus. Our patient developed a periaortic abscess in the abdominal aorta and a thoracic aortic aneurysm with ulcer-like projection (ULP), which rapidly increased in size. He was transferred to the tertiary medical institution for surgical drainage. This case suggests that bacteremia can exacerbate aneurysms with ulcerative lesions. Anaerobic bacteremia is a possible differential diagnosis when periaortic abscess formation is present. Early surgical consultation and appropriate antibiotic selection are crucial in anaerobic bacteremia treatment.

scholarly journals SYSTEMIC MANIFESTATIONS DUE TO ALLERGY

PEDIATRICS ◽  
1961 ◽  
Vol 27 (5) ◽  
pp. 790-799
Author(s):  
William G. Crook ◽  
Walton W. Harrison ◽  
Stanley E. Crawford ◽  
Blanche S. Emerson
Keyword(s):  
Nervous System ◽  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Nasal Congestion ◽  
Signs And Symptoms ◽  
Tabular Form ◽  
Case Histories ◽  
The Past ◽  
Systemic Manifestations ◽  
Symptoms And Signs

The data on 50 patients with systemic manifestations due to allergy seen at the Children's Clinic, Jackson, Tennessee, during the period 1956 through 1960 is presented. Detailed case histories are recorded for four of these patients. The findings on the remainder are given in tabular form. Uniformly, the symptoms and signs in these children were fatigue, irritability, pallor in the absence of anemia, and infraorbital circles. Most of them also had nasal congestion, abdominal pain and headache. A variety of other signs and symptoms, including those of nervous system involvement, may also be present. The literature on this condition is reviewed in detail showing that this condition has been described under several different names by many observers during the past 40 years. In spite of these descriptions, few physicians are aware that allergy causes such systemic manifestations. In conclusion, it is suggested that allergy be included in the differential diagnosis of any child with generalized body symptoms of undetermined cause.

scholarly journals A complication of a dropped appendicolith misdiagnosed as Crohn’s disease

2011 ◽  
Vol 93 (6) ◽  
pp. e117-e118 ◽  
Author(s):  
S Sarkar ◽  
L Douglas ◽  
AA Egun
Keyword(s):  
Computed Tomography ◽  
Differential Diagnosis ◽  
Unusual Complication ◽  
Abdominal Abscess ◽  
X Rays ◽  
Surgical Drainage ◽  
Past Medical History ◽  
Ct Guided ◽  
High Attenuation ◽  
The Past

Appendicoliths are formed by calcium salts and faecal debris layered and lodged within the appendix. They are detected on unenhanced x-rays in less than 10% of patients with appendicitis. When an appendicolith is found extraluminally, it is pathognomonic for perforation of the appendix. Moreover, retained appendicoliths act as a nidus for infection and are likely to be the source of a postoperative intraperitoneal abscess. However, this is very rare with only 30 reported cases of intra-abdominal abscess secondary to an appendicolith in the literature over the past 40 years. Retained, or dropped, appendicoliths most commonly present as an area of high attenuation less than 1cm in diameter with an associated abscess close to the caecum or Morrison’s pouch on computed tomography (CT). A study published in 2006 showed that although there is initial success with CT-guided drainage of abscesses secondary to faecaliths, all will recur and formal surgical drainage with removal of the appendicolith is required. This case report highlights not only an unusual complication of a retained appendicolith but also the importance of taking a thorough history and interpreting investigations in the context of the patient’s past medical history so as to produce a differential diagnosis and prevent treatment of incorrect conditions.

scholarly journals Acute abdominal pain following fracture of a heterotopically formed bone incorporating a prolene mesh

2010 ◽  
Vol 92 (6) ◽  
pp. e1-e2 ◽  
Author(s):  
H Nageswaran ◽  
A Dunkley
Keyword(s):  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Bone Formation ◽  
Abdominal Surgery ◽  
Acute Abdominal Pain ◽  
Unknown Origin ◽  
Prolene Mesh ◽  
The Past ◽  
First Case ◽  
Open Abdominal Surgery

A case is presented of severe abdominal pain around a healed scar following fracture of a heterotopically formed bone. This should be considered an unusual differential diagnosis in patients with acute pain of unknown origin who had open abdominal surgery in the past. To our knowledge, we have also reported the first case of hetertopic bone formation incorporating a prolene mesh.

scholarly journals Novel Seleno- and Thio-Urea Containing Dihydropyrrol-2-One Analogues as Antibacterial Agents

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 321
Author(s):  
Shekh Sabir ◽  
Tsz Tin Yu ◽  
Rajesh Kuppusamy ◽  
Basmah Almohaywi ◽  
George Iskander ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Antibiotic Resistance ◽  
Quorum Sensing ◽  
Antibacterial Agents ◽  
Inhibitory Concentration ◽  
Resistant Bacteria ◽  
Drug Resistant ◽  
Positive Bacterium ◽  
Quorum Sensing Inhibition ◽  
Drug Resistant Bacteria

The quorum sensing (QS) system in multi-drug-resistant bacteria such as P. aeruginosa is primarily responsible for the development of antibiotic resistance and is considered an attractive target for antimicrobial drug discovery. In this study, we synthesised a series of novel selenourea and thiourea-containing dihydropyrrol-2-one (DHP) analogues as LasR antagonists. The selenium DHP derivatives displayed significantly better quorum-sensing inhibition (QSI) activities than the corresponding sulphur analogues. The most potent analogue 3e efficiently inhibited the las QS system by 81% at 125 µM and 53% at 31 µM. Additionally, all the compounds were screened for their minimum inhibitory concentration (MIC) against the Gram-positive bacterium S. aureus, and interestingly, only the selenium analogues showed antibacterial activity, with 3c and 3e being the most potent with a MIC of 15.6 µM.

scholarly journals Baroreflex Activation Therapy for the Treatment of Drug-Resistant Hypertension: New Developments

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Teba Alnima ◽  
Peter W. de Leeuw ◽  
Abraham A. Kroon
Keyword(s):  
Resistant Hypertension ◽  
First Generation ◽  
Systolic Heart Failure ◽  
Drug Resistant ◽  
New Developments ◽  
Baroreflex Activation Therapy ◽  
Beneficial Effects ◽  
The Past ◽  
Carotid Baroreflex ◽  
Activation Therapy

In the past few years, novel accomplishments have been obtained in carotid baroreflex activation therapy (BAT) for the treatment of resistant hypertension. In addition, this field is still evolving with promising results in the reduction of blood pressure and heart rate. This overview addresses the latest developments in BAT for the treatment of drug-resistant hypertension. Although not totally understood considering the working mechanisms of BAT, it appeared to be possible to achieve at least as much efficacy of single-sided as bilateral stimulation. Therefore unlike the first-generation Rheos system, the second-generation Barostimneooperates by unilateral baroreflex activation, using a completely different carotid electrode. Also significant improvements in several cardiac parameters have been shown by BAT in hypertensive patients, which set the basis for further research to evaluate BAT as a therapy for systolic heart failure. Yet important uncertainties need to be clarified to guarantee beneficial effects; hence not all participants seem to respond to BAT.

scholarly journals Petrous apex cholesterol granuloma: pictorial review of radiological considerations in diagnosis and surgical histopathology

2013 ◽  
Vol 127 (4) ◽  
pp. 339-348 ◽  
Author(s):  
M Hoa ◽  
J W House ◽  
F H Linthicum ◽  
J L Go
Keyword(s):  
Differential Diagnosis ◽  
Surgical Management ◽  
Fibrous Tissue ◽  
Tissue Reaction ◽  
Petrous Apex ◽  
Cholesterol Granuloma ◽  
Surgical Drainage ◽  
Radiological Features ◽  
Pictorial Review ◽  
Appropriate Treatment

AbstractBackground:Petrous apex cholesterol granulomas are expansile, cystic lesions containing cholesterol crystals surrounded by foreign body giant cells, fibrous tissue reaction and chronic inflammation. Appropriate treatment relies on an accurate radiological diagnosis and an understanding of the distinguishing radiological features of relevant entities in the differential diagnosis of this condition.Methods:Firstly, this paper presents a pictorial review of the relevant radiological features of petrous apex cholesterol granuloma, and highlights unique features relevant to the differential diagnosis. Secondly, it reviews the histopathological and radiological findings associated with surgical drainage of these lesions.Results:Radiological features relevant to the differential diagnosis of petrous apex cholesterol granuloma are reviewed, together with radiological and histopathological features relevant to surgical management. Following surgical management, histopathological and radiological evidence demonstrates that the patency of the surgical drainage pathway is maintained.Conclusion:Accurate diagnosis of petrous apex cholesterol granuloma is essential in order to instigate appropriate treatment. Placement of a stent in the drainage pathway may help to maintain patency and decrease the likelihood of symptomatic recurrence.

scholarly journals Draft Genome Sequence of a Clinically Isolated Extensively Drug-Resistant Pseudomonas aeruginosa Strain

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Bhavani Manivannan ◽  
Niranjana Mahalingam ◽  
Sudhir Jadhao ◽  
Amrita Mishra ◽  
Pravin Nilawe ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Genome Assembly ◽  
Biofilm Formation ◽  
Draft Genome ◽  
Drug Resistant ◽  
Draft Genome Assembly ◽  
Extensively Drug Resistant ◽  
History Of ◽  
Urinary Tuberculosis

We present the draft genome assembly of an extensively drug-resistant (XDR) Pseudomonas aeruginosa strain isolated from a patient with a history of genito urinary tuberculosis. The draft genome is 7,022,546 bp with a G+C content of 65.48%. It carries 7 phage genomes, genes for quorum sensing, biofilm formation, virulence, and antibiotic resistance.

Huge retrovesical hydatid cyst with pelvic localization as the primary site: a case report

2007 ◽  
Vol 48 (8) ◽  
pp. 918-920 ◽  
Author(s):  
A. M. Halefoglu ◽  
A. Yasar
Keyword(s):  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Case Report ◽  
Hydatid Cyst ◽  
Cystic Mass ◽  
Primary Site ◽  
Cystic Disease ◽  
The World ◽  
Indirect Hemagglutination ◽  
Indirect Hemagglutination Test

We present a patient with symptoms of abdominal pain and frequent urination due to a huge mass in the retrovesical region. All imaging modalities revealed a cystic mass containing small daughter cysts located between the urinary bladder and rectum. Its characteristics led us to suspect the presence of a hydatid cyst, and an indirect hemagglutination test for Echinococcus granulosus was found positive. No other involvement of hydatid cystic disease was detected. The primary site for the hydatid disease was therefore regarded as the pelvis, on which only a few cases have been reported previously. The patient started albendazole therapy, but refused operation. Hydatid cyst should always be considered in the differential diagnosis of abdominopelvic masses in endemic regions of the world.

Pyogenic Liver Abscess in Normal Children With Fever of Unknown Origin

PEDIATRICS ◽  
1976 ◽  
Vol 58 (4) ◽  
pp. 614-616 ◽  
Author(s):  
Sheldon L. Kaplan ◽  
Ralph D. Feigin
Keyword(s):  
Abdominal Pain ◽  
Liver Abscess ◽  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
Pyogenic Liver Abscess ◽  
Liver Function Tests ◽  
Blood Cultures ◽  
Normal Children ◽  
The Past ◽  
Liver Abscesses

Solitary pyogenic hepatic abscesses were identified as the cause of fever, abdominal pain, and hepatomegaly in two otherwise normal children who were seen at St. Louis Children's Hospital during the past year. Liver function tests were normal and blood cultures were negative in both patients. These cases illustrate that pyogenic liver abscess may occur in normal children and should be considered whenever fever of unknown origin is associated with abdominal complaints. Only in this way can we hope to improve upon the results cited previously, namely that the majority of liver abscesses remain undiagnosed during life.

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