scholarly journals SARS-CoV-2 Translocate from Nasopharyngeal to Bronchoalveolar Site: A Case Presentation

Reports ◽  
2020 ◽  
Vol 3 (3) ◽  
pp. 23
Author(s):  
Filippo Luciani ◽  
Erika Cione ◽  
Maria Cristina Caroleo ◽  
Manuela Colosimo ◽  
Alfredo Zanolini ◽  
...  
Keyword(s):  
Case Report ◽  
Bronchoalveolar Lavage ◽  
Antiviral Therapy ◽  
Clinical Condition ◽  
Nasopharyngeal Swab ◽  
Present Case Report ◽  
Case Presentation ◽  
Severe Impairment ◽  
Negative Detection

The nasopharyngeal swab is commonly used for the diagnosis of SARS-CoV-2 infection. Since the swab is performed in this site, of course, it cannot detect the presence of the virus in other tissue districts such as the lung, brain, or bowel. In the present case report, the nasopharyngeal swab was negative twice. From this, the patient discontinued antiviral therapy. Nasopharyngeal swabs were maintained negative until five days later, when we recorded a severe impairment of the patient’s clinical condition. At this time, the bronchoalveolar lavage was positive for SARS-CoV-2. The purpose of the case herein described is to suggest paying attention to the nasopharyngeal swab result. A negative detection in nasopharyngeal swab could not be indicative of COVID-19 recovery.

Cardiac and Respiratory Arrest in a 12-Year-Old Girl with Acute Permethrin Toxicity: A Case Report

2021 ◽  
Author(s):  
Hesam Adin Atashi ◽  
Hamid Zaferani Arani ◽  
Seyyed Mojtaba Ghorani ◽  
Mahya Sadat Teimouri Khorasani ◽  
Masoumeh Moalem
Keyword(s):  
Case Report ◽  
Brain Damage ◽  
Respiratory Arrest ◽  
Spontaneous Circulation ◽  
Type I ◽  
Medical Problems ◽  
Present Case Report ◽  
Case Presentation ◽  
Hypoxic Brain Damage ◽  
Hypoxic Brain

Abstract Background: Permethrin (PER) is widely employed as the most frequently used type I synthetic pyrethroid insecticide. Despite its worldwide application, reports of pediatric toxicity following permethrin administration are scarce.Case presentation: The present case report involves a 12-year-old Afghan girl, with no previous medical problems, who drank an unknown insecticide covertly at home. Two hours after ingestion, she was taken to the emergency room with neither breathing signs nor a heartbeat. She was immediately transferred to the cardiopulmonary resuscitation (CPR) room, and her spontaneous circulation was returned after a few minutes of CPR. She was then intubated, volume resuscitated with intravenous normal saline, and connected to the mechanical ventilator after being transferred to the ICU ward. The patient remained comatose without spontaneous breathing, her pupils became bilateral mydriasis, and central diabetes insipidus became evident after three days due to apnea and hypoxic brain damage following insecticide ingestion. The chemical analysis of the insecticide bottle showed 10% permethrin without organophosphates, as initially expected. Unfortunately, after seven days, the patient passed away due to resistant hypotension and severe brain damage.Conclusion: Permethrin is widely used globally as an insecticide. However, there are many unmet needs in permethrin toxicity treatment, and the treatment is mainly supportive. Depending on the amount and dose of permethrin, the most common symptoms can vary from headache, dyspnea, and vomiting to metabolic acidosis and cardiac and respiratory arrest, which can lead to hypoxic brain damage and death, as was the outcome in our case.

scholarly journals Minimal Invasive Surgical Management of Familial Arteriovenous Malformation

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Mokhtar Mamdouh Abdel-Latif ◽  
Shankargouda Patil
Keyword(s):  
Case Report ◽  
Arteriovenous Malformation ◽  
Surgical Management ◽  
Arteriovenous Malformations ◽  
Minimal Invasive ◽  
Favorable Outcome ◽  
Significant Morbidity ◽  
Present Case Report ◽  
Case Presentation ◽  
Oral Region

Introduction. Familial arteriovenous malformations are exceedingly rare. They are often noted at birth. They can also present during childhood or adolescence. Sclerotherapy has proven to have a favorable outcome. Case Presentation. The present case report describes the treatment of arteriovenous malformations on the tongue, labial mucosa, and vermilion border in siblings treated with boiling saline injections. Conclusion. Sclerotherapy using boiling saline had shown to effectively treat arteriovenous malformations in the oral region without any significant morbidity.

scholarly journals A case report of serious brain and lung injury caused by mistakenly taking Mosquito repellent liquid contains Meperfluthrin

2020 ◽  
Author(s):  
Qing Lou ◽  
Shengxin Zhang ◽  
Shengkun Zheng ◽  
Huaying Liu ◽  
Yi Lu ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Case Report ◽  
Lung Injury ◽  
Bronchoalveolar Lavage ◽  
Daily Life ◽  
Mosquito Repellent ◽  
Case Presentation ◽  
Toxic Damage ◽  
Xiamen City ◽  
Clinical Cases

Abstract Background Mosquito repellent liquid containing Meperfluthrin is widely used in the daily life. Among all clinical cases that children take mosquito repellent by mistake, only a fewwere recorded with serious brain and lung damages caused by Meperfluthrin. Case presentation: This case report presents a 16-month-old child in Xiamen City of China with severe brain and lung injury caused by mistakenly taking mosquito repellent that contains 0.8% Meperfluthrin. The child was treated with mechanical ventilation, fiberoptic bronchoalveolar lavage, anti-infection, 20% mannitol for dehydration, ganglioside and neurologic rehabilitation. The child recovered after 2 months. Conclusion This case shows that the improper administration of Meperfluthrin may cause serious toxic damage to brain and lung. Clinicians and parents should pay attention to prevention and targeting treatment promptly after intoxication.

scholarly journals Case report of the treatment and experience of mental disorders due to chronic viral encephalitis

2021 ◽  
Vol 34 (1) ◽  
pp. e100340
Author(s):  
Mingming Zheng ◽  
Ran Bi ◽  
Yezhe Lin ◽  
Cuizhen Zhu ◽  
Daomin Zhu
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Mental Disorders ◽  
Antiviral Therapy ◽  
Clinical Diagnosis ◽  
Male Patient ◽  
Clinical Condition ◽  
Viral Encephalitis ◽  
Clinical Manifestations ◽  
Mental Symptoms

Viral encephalitis is a common clinical condition. Its clinical manifestations are variable and include neurological symptoms and psychiatric abnormalities, which makes clinical diagnosis and treatment difficult. To date, there are only a few reported cases on mental symptoms of chronic viral encephalitis. We present a case of a 16-year-old male patient who was previously hospitalised and diagnosed with schizophrenia and treated with aripiprazole 15 mg/day but failed to respond. The patient was then given antiviral therapy and recovered after 2 weeks. Clinicians should be aware of the possbility that chronic mental disorders could be caused by viral encephalitis. In the future, diagnosis of chronic functional mental disorders should include viral encephalitis in the differential diagnosis.

scholarly journals Case Report: SARS-CoV-2 as an unexpected causal agent of isolated febrile hepatitis

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 400
Author(s):  
Paraskevas Filippidis ◽  
Francois van Ouwenaller ◽  
Alberto Cerutti ◽  
Anaïs Geiger-Jacquod ◽  
Christine Sempoux ◽  
...  
Keyword(s):  
Case Report ◽  
Respiratory Symptoms ◽  
Unknown Origin ◽  
Causal Agent ◽  
Nasopharyngeal Swab ◽  
Serological Testing ◽  
Case Presentation ◽  
Pcr Screening ◽  
Work Up

Background: Respiratory symptoms and pneumonia are the predominant features of Coronavirus disease 2019 (COVID-19) due to emerging SARS-CoV-2 virus, but extrapulmonary manifestations are also observed. For instance, some degree of liver injury has been described among patients requiring hospital admission for severe COVID-19. However, acute febrile hepatitis as an initial or predominant manifestation of COVID-19 has been rarely reported. Case presentation: A 34-year-old man without underlying medical conditions presented with fever of unknown origin for two weeks in the absence of respiratory symptoms or other complaints. Laboratory testing revealed isolated acute hepatitis, for which an extensive microbiological work-up did not reveal identification of the causal agent. PCR testing for SARS-CoV-2 on a nasopharyngeal swab was negative on two occasions and initial serology for SARS-CoV-2 (at 15 days from symptoms onset) was also negative. However, repeated SARS-CoV-2 serological testing at 30 days demonstrated seroconversion leading to the diagnosis of COVID-19-related hepatitis. The patient's condition progressively improved, while transaminases steadily declined and eventually returned back to normal within 30 days. Conclusions: We describe here a unique case of SARS-CoV-2 isolated febrile hepatitis in a young and previously healthy man, which was diagnosed by demonstration of seroconversion, while PCR screening was negative. This case report highlights the role of repeated serological testing for the diagnosis of extrapulmonary manifestations of COVID-19.

scholarly journals Case Report: SARS-CoV-2 as an unexpected causal agent of predominant febrile hepatitis

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 400
Author(s):  
Paraskevas Filippidis ◽  
Francois van Ouwenaller ◽  
Alberto Cerutti ◽  
Anaïs Geiger-Jacquod ◽  
Christine Sempoux ◽  
...  
Keyword(s):  
Case Report ◽  
Respiratory Symptoms ◽  
Unknown Origin ◽  
Causal Agent ◽  
Nasopharyngeal Swab ◽  
Serological Testing ◽  
Case Presentation ◽  
Pcr Screening ◽  
Work Up

Background: Respiratory symptoms and pneumonia are the predominant features of Coronavirus disease 2019 (COVID-19) due to emerging SARS-CoV-2 virus, but extrapulmonary manifestations are also observed. For instance, some degree of liver injury has been described among patients requiring hospital admission for severe COVID-19. However, acute febrile hepatitis as an initial or predominant manifestation of COVID-19 has been rarely reported. Case presentation: A 34-year-old man without underlying medical conditions presented with fever of unknown origin for two weeks in the absence of respiratory symptoms or other complaints. Laboratory testing revealed isolated acute hepatitis, for which an extensive microbiological work-up did not reveal identification of the causal agent. PCR testing for SARS-CoV-2 on a nasopharyngeal swab was negative on two occasions and initial serology for SARS-CoV-2 (at 15 days from symptoms onset) was also negative. However, repeated SARS-CoV-2 serological testing at 30 days demonstrated seroconversion leading to the diagnosis of COVID-19-related hepatitis. The patient's condition progressively improved, while transaminases steadily declined and eventually returned back to normal within 30 days. Conclusions: We describe here a unique case of SARS-CoV-2 isolated febrile hepatitis in a young and previously healthy man, which was diagnosed by demonstration of seroconversion, while PCR screening was negative. This case report highlights the role of repeated serological testing for the diagnosis of extrapulmonary manifestations of COVID-19.

scholarly journals Detection of SARS-CoV-2 pneumonia: two case reports 

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Felix S. Seibert ◽  
Daniela Toma ◽  
Frederic Bauer ◽  
Krystallenia Paniskaki ◽  
Moritz Anft ◽  
...  
Keyword(s):  
Bronchoalveolar Lavage ◽  
Case Reports ◽  
Correct Diagnosis ◽  
Therapeutic Strategies ◽  
Nasopharyngeal Swab ◽  
Chain Reaction ◽  
Pharyngeal Swab ◽  
Case Presentation ◽  
Caucasian Patients ◽  
Polymerase Chain

Abstract Background Developing therapeutic strategies for a SARS-CoV-2 infection is challenging, but first the correct diagnosis has to be made. Unspecific upper and lower respiratory tract symptoms can be misleading; hence, a nasopharyngeal swab test with a real-time reverse-transcription-polymerase chain reaction is of great importance. However, early viral clearing jeopardizes a sound diagnosis of COVID-19. Case presentation We report on two Caucasian patients who had negative pharyngeal swab tests at the onset of SARS-CoV-2 pneumonia. In one patient, the virus was not even detectable in bronchoalveolar lavage despite typical radiomorphologic changes. Conclusions Negative PCR findings in both the pharynx and bronchoalveolar lavage do not exclude COVID-19 pneumonia. Computed tomography is a crucial diagnostic prerequisite in this context.

scholarly journals Unconventional implant strategy for patients with a limited interocclusal space in the posterior region: a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yi Wang ◽  
Wen Cen ◽  
Jiang-Qin Huang ◽  
Hong-Wu Wei
Keyword(s):  
Case Report ◽  
Minimally Invasive ◽  
Treatment Strategy ◽  
Posterior Region ◽  
Surgical Reconstruction ◽  
Treatment Alternative ◽  
Invasive Treatment ◽  
Present Case Report ◽  
Case Presentation ◽  
Implant Treatment

Abstract Background Implant prostheses require sufficient interocclusal space. In cases of limited interocclusal space, reducing or extracting over-erupted opposing teeth, orthodontic intrusion, or surgical reconstruction of the edentulous space are commonly used to restore the interocclusal space. However, there are disadvantages to these approaches. Case presentation The present case report describes a patient with a limited interocclusal space managed using an unconventional implant strategy. Conclusions The patient presented satisfactory outcomes without any signs of implant failure, suggesting that the unconventional implant treatment strategy is a useful option for patients with a limited interocclusal space in the posterior region. This unconventional implant surgery provides a minimally invasive treatment alternative.

scholarly journals Basal Ganglia Infarction a Rare Neurological Manifestation of COVID-19 in an Elderly Patient: A Case Report

2021 ◽  
Author(s):  
Manar Ahmed Kamal
Keyword(s):  
Elderly Patient ◽  
Emergency Department ◽  
Case Report ◽  
Basal Ganglia ◽  
Respiratory Symptoms ◽  
Neurological Manifestation ◽  
Nasopharyngeal Swab ◽  
Swab Sample ◽  
Limb Weakness ◽  
Case Presentation

Abstract Background: Coronavirus disease 2019 (COVID-19) is spreading rapidly worldwide since the first cases were observed in Wuhan, China. Patients with COVID-19 develop multiple neurological symptoms, including headache, disturbed consciousness, and paresthesia, in addition to systemic and respiratory symptoms. Case presentation: We presented a 57-years-old woman admitted to the emergency department (ED) - in December 2020 - with complaints of slurred speech, confusion, and left upper limb weakness after one week of positive nasopharyngeal swab sample for SARS-CoV-2. Conclusion: This case report concludes that unilateral acute basal ganglia infarction may be a unique neurological manifestation after COVID-19 infection in an elderly patient.

The recovery of an elderly woman with asthma and diabetes from COVID-19 infection: a case report

2021 ◽  
Vol 21 ◽  
Author(s):  
Abas Ghaysouri ◽  
Maryam Safari ◽  
Elham Mohammadyari ◽  
Firooz Balavandi ◽  
Ali Nazari ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Condition ◽  
Elderly Woman ◽  
Advanced Age ◽  
Respiratory Complications ◽  
Case Presentation ◽  
Good Clinical Condition ◽  
History Of ◽  
Therapeutic Measures ◽  
Underlying Diseases

Introduction: COVID-19 has caused a great deal of fear indifferent communities. In this study, we reported the recovery of a diabetic elderly woman with a history of asthmafromCOVID-19 infection. Case Presentation: A 61-year-old woman was hospitalized due to dyspnea and low blood O2 saturation and later diagnosed with COVID-19, as confirmed by PCR. The patient had a history of asthma and diabetes and used salbutamol and Atrovent spray. She also had a history of hospitalization at one month prior to the current admission. Despite all these, COVID-19was successfully managed, and she was discharged with a good clinical condition after the improvement of respiratory complications. Conclusion: Despite having an advanced age and underlying diseases (diabetes and asthma), the recovery of this elderly woman shows that even such patientscandefeatCOVID-19 as long as the disease is not progressed to advanced phases and appropriate therapeutic measures are taken. By reporting such cases, it is possible to give people hope and motivation and reduce their fear of the disease.

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