scholarly journals “Harms” Associated with Breast Cancer Screening and Reliability of Frozen Section in Older Women: In the Case of an 80 Year Old Woman

Reports ◽  
2020 ◽  
Vol 3 (2) ◽  
pp. 15
Author(s):  
Evangelia Antoniou ◽  
Stefanos Zervoudis ◽  
Andriani Vouxinou ◽  
Anastasia Bothou ◽  
Anisa Markja ◽  
...  

The objective of this paper is to present a rare case with negative final histologic examination despite abnormal findings of all previous exams indicating breast cancer in an 80 year old woman. Mammographic and magnetic resonance imaging findings were concordant with the frozen section biopsy result of DCIS. However, the final histologic diagnosis was radial scar (benign breast lesion that can radiologically mimic malignancy). As a conclusion, abnormal mammographic and magnetic resonance imaging findings with positive for DCIS frozen section reports are not always confirmed in the final histologic examination. Furthermore, considering that screening does not seem to be associated with a reduction in mortality due to breast cancer after the age of 75, breast cancer screening could be individualized in this age group.

2005 ◽  
Vol 60 (2) ◽  
pp. 107-109 ◽  
Author(s):  
Mieke Kriege ◽  
Cecile T. M. Brekelmans ◽  
Carla Boetes ◽  
Peter E. Besnard ◽  
Harmine M. Zonderland ◽  
...  

2019 ◽  
Vol 70 (1) ◽  
pp. 501-519 ◽  
Author(s):  
Christiane K. Kuhl

Given the increasing understanding of cancer as a heterogeneous group of diseases, detection methods should offer a sensitivity profile that ensures perfect sensitivity for biologically important cancers while screening out self-limiting pseudocancers. However, mammographic screening is biased toward detection of ductal carcinoma in situ and slowly growing cancers—and thus frequently fails to detect biologically aggressive cancers. This explains the persistently high rates of interval cancers and high rates of breast cancer mortality observed in spite of decades of mammographic screening. Magnetic resonance imaging (MRI), in contrast, has a sensitivity profile that matches clinical needs. Conventional MRI is not suitable for population-wide screening due to high cost, limited tolerability, and lack of availability. We introduced abbreviated MRI in 2014. Abbreviated MRI will change the way MRI is used in clinical medicine. This article describes the rationale to use MRI in general, and abbreviated MRI in particular, for breast cancer screening.


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