Bladder Substitution: The Role of Tissue Engineering and Biomaterials

Martina Casarin; Alessandro Morlacco; Fabrizio Dal Moro

doi:10.3390/pr9091643

Bladder Substitution: The Role of Tissue Engineering and Biomaterials

Processes ◽

10.3390/pr9091643 ◽

2021 ◽

Vol 9 (9) ◽

pp. 1643

Author(s):

Martina Casarin ◽

Alessandro Morlacco ◽

Fabrizio Dal Moro

Keyword(s):

Tissue Engineering ◽

Urinary Diversion ◽

Mucus Production ◽

Reconstructive Procedures ◽

Suitable Material ◽

Orthotopic Urinary Diversion ◽

Bladder Substitution ◽

Materials Used ◽

Bowel Segments

Tissue engineering could play a major role in the setting of urinary diversion. Several conditions cause the functional or anatomic loss of urinary bladder, requiring reconstructive procedures on the urinary tract. Three main approaches are possible: (i) incontinent cutaneous diversion, such as ureterocutaneostomy, colonic or ileal conduit, (ii) continent pouch created using different segments of the gastrointestinal system and a cutaneous stoma, and (iii) orthotopic urinary diversion with an intestinal segment with spherical configuration and anastomosis to the urethra (neobladder, orthotopic bladder substitution). However, urinary diversions are associated with numerous complications, such as mucus production, electrolyte imbalances and increased malignant transformation potential. In this context, tissue engineering would have the fundamental role of creating a suitable material for urinary diversion, avoiding the use of bowel segments, and reducing complications. Materials used for the purpose of urinary substitution are biological in case of acellular tissue matrices and naturally derived materials, or artificial in case of synthetic polymers. However, only limited success has been achieved so far. The aim of this review is to present the ideal properties of a urinary tissue engineered scaffold and to examine the results achieved so far. The most promising studies have been highlighted in order to guide the choice of scaffolds and cells type for further evolutions.

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Materials for Dentoalveolar Bioprinting: Current State of the Art

Biomedicines ◽

10.3390/biomedicines10010071 ◽

2021 ◽

Vol 10 (1) ◽

pp. 71

Author(s):

Mehdi Salar Amoli ◽

Mostafa EzEldeen ◽

Reinhilde Jacobs ◽

Veerle Bloemen

Keyword(s):

Tissue Engineering ◽

State Of The Art ◽

Patient Specific ◽

Biological Scaffolds ◽

Suitable Material ◽

Novel Technologies ◽

Current State ◽

Wide Range ◽

Regenerative Approach ◽

Materials Used

Although current treatments can successfully address a wide range of complications in the dentoalveolar region, they often still suffer from drawbacks and limitations, resulting in sub-optimal treatments for specific problems. In recent decades, significant progress has been made in the field of tissue engineering, aiming at restoring damaged tissues via a regenerative approach. Yet, the translation into a clinical product is still challenging. Novel technologies such as bioprinting have been developed to solve some of the shortcomings faced in traditional tissue engineering approaches. Using automated bioprinting techniques allows for precise placement of cells and biological molecules and for geometrical patient-specific design of produced biological scaffolds. Recently, bioprinting has also been introduced into the field of dentoalveolar tissue engineering. However, the choice of a suitable material to encapsulate cells in the development of so-called bioinks for bioprinting dentoalveolar tissues is still a challenge, considering the heterogeneity of these tissues and the range of properties they possess. This review, therefore, aims to provide an overview of the current state of the art by discussing the progress of the research on materials used for dentoalveolar bioprinting, highlighting the advantages and shortcomings of current approaches and considering opportunities for further research.

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Orthotopic Urinary Diversion Using an Ileal Low-Pressure Bladder Substitute with an Afferent Tubular Segment

Atlas of the Urologic Clinics ◽

10.1016/s1063-5777(05)70091-8 ◽

2001 ◽

Vol 9 (2) ◽

pp. 57-73 ◽

Cited By ~ 6

Author(s):

F.C. Burkhard ◽

U.E. Studer

Keyword(s):

Urinary Diversion ◽

Low Pressure ◽

Orthotopic Urinary Diversion

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HYDROXYAPATITE, ALGINATE, AND CHITOSAN FOR BONE SCAFFOLDS: SPECTROSCOPY STUDY

Dentika Dental Journal ◽

10.32734/dentika.v19i2.457 ◽

2016 ◽

Vol 19 (2) ◽

pp. 93-100

Author(s):

Lalita El Milla

Keyword(s):

Tissue Engineering ◽

Bone Tissue Engineering ◽

Bone Tissue ◽

Functional Groups ◽

Bone Growth ◽

Three Dimensional ◽

Dimensional Structure ◽

Tissue Engineering Scaffolds ◽

Hydroxyapatite Powder ◽

Materials Used

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.

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Calculations used for assessment of rapid maxillary expansion

ORL ro ◽

10.26416/orl.30.1.2016.525 ◽

2016 ◽

Vol 1 (1) ◽

pp. 24-26

Author(s):

Ruxandra Bartok ◽

Bogdan Dimitriu Dimitriu ◽

Constantin Vârlan ◽

Radu Stanciu ◽

Georgiana Moldoveanu ◽

...

Keyword(s):

Tensile Strength ◽

Elasticity Modulus ◽

Rapid Maxillary Expansion ◽

Laboratory Animals ◽

Maxillary Expansion ◽

Literature Reference ◽

Bone Changes ◽

Upper Jaw ◽

Materials Used

Rapid maxillary expansion is defined as the release of medio-palatine suture using an orthopedic forces. The role of this procedure is to expand the upper jaw in order to achieve the broadening of the upper arch. This study was initiated to quantify the effects of disjunction and post- treatment bone changes, after an adequate contention which lasted for three weeks. This study is carried on laboratory animals (common breed rabbit) to determine tensile strength and the elasticity modulus of biological materials used in orthdodontics. The results of the study are consistent with those reported in the literature reference.

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Faculty Opinions recommendation of Low-dose oral desmopressin for treatment of nocturia and nocturnal enuresis in patients after radical cystectomy and orthotopic urinary diversion.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718201486.793537901 ◽

2017 ◽

Author(s):

Kristian Vinter Juul

Keyword(s):

Radical Cystectomy ◽

Urinary Diversion ◽

Nocturnal Enuresis ◽

Low Dose ◽

Orthotopic Urinary Diversion ◽

Dose Oral

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Role of Growth Factors and Endothelial Cells in Therapeutic Angiogenesis and Tissue Engineering

Current Stem Cell Research & Therapy ◽

10.2174/157488806778226777 ◽

2006 ◽

Vol 1 (3) ◽

pp. 333-343 ◽

Cited By ~ 62

Author(s):

Masashi Nomi ◽

Hideaki Miyake ◽

Yoshifumi Sugita ◽

Masato Fujisawa ◽

Shay Soker

Keyword(s):

Tissue Engineering ◽

Endothelial Cells ◽

Growth Factors ◽

Therapeutic Angiogenesis

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Bio-Based Alternatives to Phenol and Formaldehyde for the Production of Resins

Polymers ◽

10.3390/polym12102237 ◽

2020 ◽

Vol 12 (10) ◽

pp. 2237 ◽

Cited By ~ 2

Author(s):

P. R. Sarika ◽

Paul Nancarrow ◽

Abdulrahman Khansaheb ◽

Taleb Ibrahim

Keyword(s):

Raw Materials ◽

Phenol Formaldehyde ◽

Raw Material ◽

Wood Industry ◽

Suitable Material ◽

The Past ◽

Wide Range ◽

Recent Developments ◽

Sustainable Materials ◽

Materials Used

Phenol–formaldehyde (PF) resin continues to dominate the resin industry more than 100 years after its first synthesis. Its versatile properties such as thermal stability, chemical resistance, fire resistance, and dimensional stability make it a suitable material for a wide range of applications. PF resins have been used in the wood industry as adhesives, in paints and coatings, and in the aerospace, construction, and building industries as composites and foams. Currently, petroleum is the key source of raw materials used in manufacturing PF resin. However, increasing environmental pollution and fossil fuel depletion have driven industries to seek sustainable alternatives to petroleum based raw materials. Over the past decade, researchers have replaced phenol and formaldehyde with sustainable materials such as lignin, tannin, cardanol, hydroxymethylfurfural, and glyoxal to produce bio-based PF resin. Several synthesis modifications are currently under investigation towards improving the properties of bio-based phenolic resin. This review discusses recent developments in the synthesis of PF resins, particularly those created from sustainable raw material substitutes, and modifications applied to the synthetic route in order to improve the mechanical properties.

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Role of PEGylated CdSe-ZnS quantum dots on structural and functional properties of electrospun polycaprolactone scaffolds for blood vessel tissue engineering

European Polymer Journal ◽

10.1016/j.eurpolymj.2021.110430 ◽

2021 ◽

Vol 151 ◽

pp. 110430

Author(s):

Soumya Columbus ◽

Diksha Painuly ◽

Renjith P. Nair ◽

V. Kalliyana Krishnan

Keyword(s):

Tissue Engineering ◽

Quantum Dots ◽

Blood Vessel ◽

Functional Properties ◽

Structural And Functional Properties

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Electrospun Nanofibrous Membranes for Tissue Engineering and Cell Growth

Applied Sciences ◽

10.3390/app11156929 ◽

2021 ◽

Vol 11 (15) ◽

pp. 6929

Author(s):

Ewin Tanzli ◽

Andrea Ehrmann

Keyword(s):

Tissue Engineering ◽

Cell Growth ◽

Polymer Blends ◽

Mammalian Cells ◽

Biological Properties ◽

Specific Substrate ◽

Electrospun Nanofiber ◽

Materials Used ◽

Nanofiber Mats ◽

Surface Morphologies

In biotechnology, the field of cell cultivation is highly relevant. Cultivated cells can be used, for example, for the development of biopharmaceuticals and in tissue engineering. Commonly, mammalian cells are grown in bioreactors, T-flasks, well plates, etc., without a specific substrate. Nanofibrous mats, however, have been reported to promote cell growth, adhesion, and proliferation. Here, we give an overview of the different attempts at cultivating mammalian cells on electrospun nanofiber mats for biotechnological and biomedical purposes. Starting with a brief overview of the different electrospinning methods, resulting in random or defined fiber orientations in the nanofiber mats, we describe the typical materials used in cell growth applications in biotechnology and tissue engineering. The influence of using different surface morphologies and polymers or polymer blends on the possible application of such nanofiber mats for tissue engineering and other biotechnological applications is discussed. Polymer blends, in particular, can often be used to reach the required combination of mechanical and biological properties, making such nanofiber mats highly suitable for tissue engineering and other biotechnological or biomedical cell growth applications.

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