scholarly journals Automating Laboratory Processes by Connecting Biotech and Robotic Devices—An Overview of the Current Challenges, Existing Solutions and Ongoing Developments

Processes ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 966
Author(s):  
Ferdinand Biermann ◽  
Julius Mathews ◽  
Bastian Nießing ◽  
Niels König ◽  
Robert Schmitt
Keyword(s):  
Data Access ◽  
Efficient Production ◽  
Open Platform ◽  
External Software ◽  
Automated Processing ◽  
Treatment Technologies ◽  
Biotechnological Processes ◽  
Robotic Devices ◽  
Regenerative Therapies ◽  
Application Specific

The constantly growing interest and range of applications of advanced cell, gene and regenerative therapies raise the need for efficient production of biological material and novel treatment technologies. Many of the production and manipulation processes of such materials are still manual and, therefore, need to be transferred to a fully automated execution. Developers of such systems face several challenges, one of which is mechanical and communication interfaces in biotechnological devices. In the present state, many devices are still designed for manual use and rarely provide a connection to external software for receiving commands and sending data. However, a trend towards automation on the device market is clearly visible, and the communication protocol, Open Platform Communications Data Access (OPC DA), seems to become established as a standard in biotech devices. A rising number of vendors offer software for device control and automated processing, some of which even allow the integration of devices from multiple manufacturers. The high, application-specific need in functionalities, flexibility and adaptivity makes it difficult to find the best solution and, in many cases, leads to the creation of new custom-designed software. This report shall give an overview of existing technologies, devices and software for laboratory automation of biotechnological processes. Furthermore, it presents an outlook for possible future developments and standardizations.

scholarly journals A survey on the attitudes of parents with young children on in-home monitoring technologies and study designs for infant research

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0245793
Author(s):  
Laurel A. Fish ◽  
Emily J. H. Jones
Keyword(s):  
Home Monitoring ◽  
Data Access ◽  
Great Promise ◽  
Infant Research ◽  
Positive Attitudes ◽  
Automated Processing ◽  
International Data ◽  
Video And Audio ◽  
Monitoring Technologies ◽  
Study Designs

Remote in-home infant monitoring technologies hold great promise for increasing the scalability and safety of infant research (including in regard to the current Covid-19 pandemic), but remain rarely employed. These technologies hold a number of fundamental challenges and ethical concerns that need addressing to aid the success of this fast-growing field. In particular, the responsible development of such technologies requires caregiver input. We conducted a survey of the opinions of 410 caregivers on the viability, privacy and data access of remote in-home monitoring technologies and study designs. Infant-friendly wearable devices (such as sensing body suits) were viewed favourably. Caregivers were marginally more likely to accept video and audio recording in the home if data was anonymised (through automated processing) at point of collection, particularly when observations were lengthy. Caregivers were more open to international data sharing for anonymous data. Caregivers were interested in viewing all types of data, but were particularly keen to access video and audio recordings for censoring purposes (i.e., to delete data segments). Taken together, our results indicate generally positive attitudes to remote in-home monitoring technologies and studies for infant research but highlight specific considerations such as safety, privacy and family practicalities (e.g. multiple caregivers, visitors and varying schedules) that must be taken into account when developing future studies.

Design of Automated Catwalks Machine Control System for Offshore Drilling Platform

2014 ◽  
Vol 568-570 ◽  
pp. 1143-1146
Author(s):  
Shu Fen Qi ◽  
Shi Ping Cheng ◽  
Wen Long Wang ◽  
Kun Zhang
Keyword(s):  
Pid Control ◽  
Automatic System ◽  
Control Algorithm ◽  
Drill String ◽  
Efficient Production ◽  
Labor Intensity ◽  
Offshore Drilling ◽  
Whole Process ◽  
Automated Processing ◽  
Machine Control

In recent years, the use of drill string automated processing systems on offshore drilling platform has become more and more widespread, and it not only can improve the efficiency of workers, but also can reduce the labor intensity. In order to make the automatic system more intelligent and more efficient in the whole process, in this paper, we designed a set of adjustable speed drill delivery system, which is based on PID control algorithm. It can not only improve the efficiency of the automated catwalks machine conveying pipe, but also ensure the quick and efficient production.

Application-Specific Fault Tolerance via Data Access Characterization

2011 ◽  
pp. 340-352 ◽  
Author(s):  
Nawab Ali ◽  
Sriram Krishnamoorthy ◽  
Niranjan Govind ◽  
Karol Kowalski ◽  
Ponnuswamy Sadayappan
Keyword(s):  
Fault Tolerance ◽  
Data Access ◽  
Application Specific

scholarly journals LIGHT WEIGHT SECURITY FOR OPC UA BASED ARCHITECTURE

2013 ◽  
pp. 46-48
Author(s):  
VARUN SHIVAPRASAD ◽  
KALLINATHA H. D.
Keyword(s):  
Data Access ◽  
Public Key Cryptography ◽  
Remote Access ◽  
Transport Layer ◽  
Communication Overhead ◽  
Time Duration ◽  
Open Platform ◽  
Multiple Keys ◽  
Time Critical ◽  
The Relationship

The open platform communication (OPC) is becoming the universal standard for platform independent data sharing and data access. The OPC standard defines communication standards to be followed for data integration in the automation industry. The OPC communication facilitates a language independent way of communication and by using this, all devices can communicate with a centralized or a distributed server in the network. The server will provide clients with facilities such as data monitoring, access and to change values in the devices in the network. The OPC UA provides security add-ons such as security in the transport layer which is mainly the Secure Sockets Layer (SSL). But the SSL adds more load on the security as it involves handshake/key-distribution which consists of a costly public key cryptography. This also puts more load on the server to store and maintain multiple keys involving multiple clients. We believe that a if a framework based on shared key is used, which will be persistent for the whole time duration of the relationship, the communication overhead can be reduced in remote access. This helps in reducing the response time of the already time critical OPC UA based architectures which requires devices to work in real time and put as much less load as possible on the server.

scholarly journals Novel Developments of the MetaCrop Information System for Facilitating Systems Biological Approaches

2010 ◽  
Vol 7 (3) ◽  
Author(s):  
Klaus Hippe ◽  
Christian Colmsee ◽  
Tobias Czauderna ◽  
Eva Grafahrend-Belau ◽  
Björn H. Junker ◽  
...  
Keyword(s):  
Information System ◽  
Web Services ◽  
Renewable Resources ◽  
Data Access ◽  
Crop Plants ◽  
Web Interface ◽  
Fine Grained ◽  
System A ◽  
External Software ◽  
High Quality Information

SummaryCrop plants play a major role in human and animal nutrition and increasingly contribute to chemical or pharmaceutical industry and renewable resources. In order to achieve important goals, such as the improvement of growth or yield, it is indispensable to understand biological processes on a detailed level. Therefore, the well-structured management of fine-grained information about metabolic pathways is of high interest. Thus, we developed the MetaCrop information system, a manually curated repository of high quality information concerning the metabolism of crop plants. However, the data access to and flexible export of information of MetaCrop in standard exchange formats had to be improved. To automate and accelerate the data access we designed a set of web services to be integrated into external software. These web services have already been used by an add-on for the visualisation toolkit VANTED. Furthermore, we developed an export feature for the MetaCrop web interface, thus enabling the user to compose individual metabolic models using SBML.

scholarly journals A DICOM-based streaming service for the Digital Operating Room

2009 ◽  
Author(s):  
Adrian m. Vazquez ◽  
Rafael Mayoral ◽  
Oliver Burgert
Keyword(s):  
Operating Room ◽  
Data Access ◽  
Streaming Data ◽  
Context Information ◽  
Data Streaming ◽  
Early Integration ◽  
Common Interface ◽  
Streaming Service ◽  
Application Specific ◽  
Digital Operating Room

In the Digital Operating Room there is a need to support data streaming to create advanced integrated surgical assist systems. In this paper we propose a DICOM-based streaming mechanism which leverages the interoperability definitions offered by DICOM to offer a common interface to manage all kinds of streaming data sources, while allowing data and application-specific protocols and infrastructure for the actual data access. We have implemented the proposed solution within the ASTMA project and have shown that thanks to the flexibility in choosing an appropriate streaming protocol we can achieve the necessary streaming quality while transmitting the context information required to create valid DICOM instances. This approach ensures an early integration of streaming data with the rest of the imaging information providing for a simpler data workflow.

Convergent-beam thickness determination: The advantages of digital imaging

1994 ◽  
Vol 52 ◽  
pp. 420-421
Author(s):  
Stuart McKernan ◽  
C. Barry Carter
Keyword(s):  
Intensity Variation ◽  
Convergent Beam Electron Diffraction ◽  
Digital Data ◽  
Thickness Determination ◽  
Frequent Use ◽  
Automated Processing ◽  
Beam Thickness ◽  
Convergent Beam ◽  
Remarkable Agreement

Convergent-beam electron diffraction (CBED) patterns contain an immense amount of information relating to the structure of the material from which they are obtained. The analysis of these patterns has progressed to the point that under appropriate, well specified conditions, the intensity variation within the CBED discs may be understood in a quantitative sense. Rossouw et al for example, have produced numerical simulations of zone-axis CBED patterns which show remarkable agreement with experimental patterns. Spence and co-workers have obtained the structure factor parameters for lowindex reflections using the intensity variation in 2-beam CBED patterns. Both of these examples involve the use of digital data. Perhaps the most frequent use for quantitative CBED analysis is the thickness determination described by Kelly et al. This analysis has been implemented in a variety of different ways; from real-time, in-situ analysis using the microscope controls, to measurements of photographic prints with a ruler, to automated processing of digitally acquired images. The potential advantages of this latter process will be presented.

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