scholarly journals Scope and Limitations of the Mathematical Models Developed for the Forward Feed Multi-Effect Distillation Process—A Review

Processes ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 1174
Author(s):  
Omer Mohamed Abubaker Al-Hotmani ◽  
Mudhar Abdul Alwahab Al-Obaidi ◽  
Yakubu Mandafiya John ◽  
Raj Patel ◽  
Iqbal M Mujtaba
Keyword(s):  
Process Design ◽  
Process Model ◽  
Review Paper ◽  
Process Development ◽  
Improvement Strategy ◽  
Advantages And Disadvantages ◽  
Thermal Desalination ◽  
Quality Water ◽  
The One ◽  
Generic Process

Desalination has become one of the obvious solutions for the global water crisis due to affording high-quality water from seawater and brackish water resources. As a result, there are continuing efforts being made to improve desalination technologies, especially the one producing high-quantity freshwater, i.e., thermal desalination. This improvement must be accomplished via enhancement of process design through optimization which is implicitly dependent on providing a generic process model. Due to the scarcity of a comprehensive review paper for modeling multi-effect distillation (MED) process, this topic is becoming more important. Therefore, this paper intends to capture the evolution of modeling the forward feed MED (most common type) and shed a light on its branches of steady-state and dynamic modeling. The maturity of the models developed for MED will be thoroughly reviewed to clarify the general efforts made highlighting the advantages and disadvantages. Depending on the outputs of this review, the requirements of process development and emerging challengeable matters of modeling will be specified. This, in turn, would afford a possible improvement strategy to gain a reliable and sustainable thermal desalination process.

scholarly journals Peptide Isolation via Spray Drying: Particle Formation, Process Design and Implementation for the Production of Spray Dried Glucagon

2020 ◽  
Vol 37 (12) ◽  
Author(s):  
Frederik J. S. Doerr ◽  
Lee J. Burns ◽  
Becky Lee ◽  
Jeremy Hinds ◽  
Rebecca L. Davis-Harrison ◽  
...  
Keyword(s):  
Spray Drying ◽  
Process Design ◽  
Formation Process ◽  
Process Model ◽  
Process Development ◽  
Pharmaceutical Formulations ◽  
Particle Formation ◽  
Operating Conditions ◽  
Residual Moisture ◽  
Process Implementation

Abstract Purpose Spray drying plays an important role in the pharmaceutical industry for product development of sensitive bio-pharmaceutical formulations. Process design, implementation and optimisation require in-depth knowledge of process-product interactions. Here, an integrated approach for the rapid, early-stage spray drying process development of trehalose and glucagon on lab-scale is presented. Methods Single droplet drying experiments were used to investigate the particle formation process. Process implementation was supported using in-line process analytical technology within a data acquisition framework recording temperature, humidity, pressure and feed rate. During process implementation, off-line product characterisation provided additional information on key product properties related to residual moisture, solid state structure, particle size/morphology and peptide fibrillation/degradation. Results A psychrometric process model allowed the identification of feasible operating conditions for spray drying trehalose, achieving high yields of up to 84.67%, and significantly reduced levels of residual moisture and particle agglomeration compared to product obtained during non-optimal drying. The process was further translated to produce powders of glucagon and glucagon-trehalose formulations with yields of >83.24%. Extensive peptide aggregation or degradation was not observed. Conclusions The presented data-driven process development concept can be applied to address future isolation problems on lab-scale and facilitate a systematic implementation of spray drying for the manufacturing of sensitive bio-pharmaceutical formulations.

Hybrid polymer composite materials. Part 2. Preparation technology

2020 ◽  
pp. 8-13
Keyword(s):  
Composite Materials ◽  
Impact Toughness ◽  
Polymer Composites ◽  
The Other ◽  
Polymer Materials ◽  
Hybrid Polymer ◽  
Preparation Technology ◽  
Advantages And Disadvantages ◽  
Hybrid Polymer Composite ◽  
The One

The main methods (pressing and winding) of the processing of hybrid polymer composites to obtain items were examined. Advantages and disadvantages of the methods were noted. Good combinations of different-module fibers (carbon, glass, boron, organic) in hybrid polymer materials are described, which allow one to prepare materials with high compression strength on the one hand, and to increase fracture energy of samples and impact toughness on the other hand.

A Review of Drug Side Effect Identification Methods

2020 ◽  
Vol 26 (26) ◽  
pp. 3096-3104 ◽  
Author(s):  
Shuai Deng ◽  
Yige Sun ◽  
Tianyi Zhao ◽  
Yang Hu ◽  
Tianyi Zang
Keyword(s):  
Side Effects ◽  
Future Research ◽  
Drug Side Effects ◽  
Important Indicator ◽  
Advantages And Disadvantages ◽  
Key Points ◽  
Network Methods ◽  
Future Research Directions ◽  
The One ◽  
Approved Drugs

Drug side effects have become an important indicator for evaluating the safety of drugs. There are two main factors in the frequent occurrence of drug safety problems; on the one hand, the clinical understanding of drug side effects is insufficient, leading to frequent adverse drug reactions, while on the other hand, due to the long-term period and complexity of clinical trials, side effects of approved drugs on the market cannot be reported in a timely manner. Therefore, many researchers have focused on developing methods to identify drug side effects. In this review, we summarize the methods of identifying drug side effects and common databases in this field. We classified methods of identifying side effects into four categories: biological experimental, machine learning, text mining and network methods. We point out the key points of each kind of method. In addition, we also explain the advantages and disadvantages of each method. Finally, we propose future research directions.

Comparison of a Non Electrostatic Surface Complexation Model and Surface Phase Theories for Prediction of Future Sorption Properties.

2004 ◽  
Vol 824 ◽  
Author(s):  
Allan T. Emrén ◽  
Anna-Maria Jacobsson
Keyword(s):  
Aqueous Solution ◽  
Chemical Potential ◽  
Surface Complexation ◽  
Sorption Properties ◽  
Phase Method ◽  
Detailed Knowledge ◽  
Surface Phase ◽  
Surface Complexation Model ◽  
Advantages And Disadvantages ◽  
The One

AbstractIn performance assessments, sorption of radionuclides dissolved in groundwater is mostly handled by the use of fixed Kd values. It has been well known that this approach is unsatisfying. Only during the last few years, however, tools have become available that make it possible to predict the actual Kd value in an aqueous solution that differs from the one in which the sorption properties were measured.One such approach is surface complexation (SC) that gives a detailed knowledge of the sorption properties. In SC, one tries to find what kinds of sorbed species are available on the surface and the thermodynamics for their formation from species in the bulk aqueous solution. Recently, a different approach, surface phase method (SP), has been developed. In SP, a thin layer including the surface is treated as a separate phase. In the bulk aqueous solution, the surface phase is treated as a virtual component, and from the chemical potential of this component, the sorption properties can be found.In the paper, we compare advantages and disadvantages of the two kinds of models. We also investigate the differences in predicted sorption properties of a number of radionuclides (Co, Np, Th and U). Furthermore, we discuss under which circumstances, one approach or the other is preferable.

Cycles in symbol production? A new model to explain concentration, diversity and innovation in the music industry

Popular Music ◽  
1995 ◽  
Vol 14 (1) ◽  
pp. 55-93 ◽  
Author(s):  
Michael Christianen
Keyword(s):  
Negative Correlation ◽  
Music Industry ◽  
The Other ◽  
Recording Industry ◽  
Cultural Goods ◽  
New Model ◽  
Advantages And Disadvantages ◽  
Factors Influencing ◽  
Using Data ◽  
The One

With the publication of the article ‘Cycles in symbol production’ (Peterson and Berger 1975) a discussion started concerning the advantages and disadvantages of the production of cultural goods under market conditions. The analysis by Peterson and Berger showed a negative correlation between concentration in the recording industry, on the one hand, and the diversity and innovativeness of the music, on the other. Repetition of the analysis using data from the 1980s (Burnett 1990; Lopes 1992) has shown that for this period Peterson and Berger's hypotheses should be rejected. Is there a connection between concentration and diversity and innovation? Are there cycles in symbol production? There seems to be no conclusive answer. In this article, I will attempt to clear up this matter. First, I will repeat the analysis of the relation between concentration and diversity/innovation, using the same model as Peterson and Berger, but with different definitions for the variables concentration, diversity and innovation. Then I will suggest a new model, which can be helpful in uncovering other factors influencing diversity and innovation in the music industry. I will come to that later. Let me first give the reader a brief overview of previous research.

An Air Texturing Process for Hybridization of Different Reinforcement Filament Yarns by Commingling Process

2006 ◽  
Vol 532-533 ◽  
pp. 333-336 ◽  
Author(s):  
Bok Choon Kang ◽  
Chathura Nalendra Herath ◽  
Jong Kwang Park ◽  
Yong Hwang Roh
Keyword(s):  
High Performance ◽  
Process Development ◽  
Glass Fibers ◽  
Air Pressure ◽  
Practical Applications ◽  
Advantages And Disadvantages ◽  
Significant Parameter ◽  
Air Jet ◽  
Yarn Count ◽  
Air Nozzle

Carbon, aramid and glass fibers are inherently superior to conventional textile fibers in terms of mechanical properties and other characteristics. However, each material has its inherent advantages and disadvantages and it is usually recommended to hybridize them to fully benefit of their high performance in practical applications to many products. This paper is concerned with an air texturing process for hybridization of different reinforcement filament yarns. A normal air texturing machine was selected for process development and modified to suit testing purposes. The modified process for hybridization was introduced mainly in terms of air-jet nozzles employed in experiments. With the proposed air texturing process machine, three types of air-nozzle were applied to the experimental work. Three different filament materials were employed in experiments and they are carbon (CF), aramid (AF), and glass (GF). As matrix materials, polyether-ether (PEEK), polyester (PES), and polypropylene (PP) were selected and experimented. Hybrid yarns produced form the proposed process was evaluated optically in terms of bulkiness, arranging, breaking, and mixing, respectively. The experimental results were also summarized in terms of relationships between applied air pressure and yarn count, and variation in count. As a whole, it was concluded from the experiments that the proposed texturing process could be successfully applied to the practical hybridization of different reinforcement filament yarns. It was also revealed from the experiments that the air pressure in the proposed process is not a significant parameter on the pressing in terms of yarn count.

scholarly journals Overtourism: Between the Right to Travel and Residents’ Rights

2019 ◽  
Vol 11 (7) ◽  
pp. 2138 ◽  
Author(s):  
Dalia Perkumienė ◽  
Rasa Pranskūnienė
Keyword(s):  
Review Paper ◽  
Sustainable Tourism ◽  
The Other ◽  
Integrative Review ◽  
Research Development ◽  
Tourism Research ◽  
Review Analysis ◽  
Preliminary Work ◽  
The One ◽  
The Right

Debates on overtourism, as a challenging phenomenon, are becoming more and more active. The purpose of this integrative review paper is to discuss the right to travel and residents’ rights in the context of overtourism and sustainable tourism, analyzing different scientific and legal sources. The integrative review analysis shows that overtourism and sustainable tourism are important contexts influencing the changing meaning of the right to travel and the right to live. On the one hand, the overtourism context makes the voices of residents more important to be heard, while on the other hand the sustainable tourism context influences the discussion of the right to travel, asking tourist voices to be considered more important. The results of this integrative review also shows the importance of rethinking the concept of sustainability in tourism as a holistic principle of democracy and as a degrowth movement, and opens the broader discussion for future tourism research development. The problem of overtourism could be solved by striving to develop sustainable tourism goals, thus balancing equality between the right to travel and residents’ rights. The presented integrative review paper is a preliminary work; further research is needed in order to find possible concrete solutions for overtourism.

scholarly journals DEVELOPMENT OF THE MODEL OF STUDENTS’ INDEPENDENT WORK UNDER CONDITIONS OF DISTANCE LEARNING

2021 ◽  
pp. 273-289
Author(s):  
Olena Osadcha
Keyword(s):  
Distance Learning ◽  
Information Technologies ◽  
The Other ◽  
Advantages And Disadvantages ◽  
Other Hand ◽  
The One ◽  
Independent Work ◽  
Further Development

The article deals with the development of the model of students’ independent work under conditions of distance learning. The importance of the research into this problem is determined, on the one hand, by the growing possibilities of using various information technologies and, on the other hand by the necessity to adapt to the conditions of today’s world where independent work of students is becoming increasingly important. The advantages and disadvantages of distance learning have been explored. The author studied the role of independent work in the formation of the professional competences of students. The issue of modeling in the area of education has been tackled. The approaches to the development of the model of independent work have been identified and analyzed. The components of the model, such as the goal, the tasks, the content, the methods, the means and evaluation of results have been determined and characterized. The prospects of further development of this research are related to the exploration of models of independent work of students majoring in different areas.

scholarly journals CLASSICAL PHOTOGRAMMETRY AND UAV – SELECTED ASCPECTS

2016 ◽  
Vol XLI-B1 ◽  
pp. 947-952 ◽  
Author(s):  
S. Mikrut
Keyword(s):  
Aerial Images ◽  
Relevant Research ◽  
The Road ◽  
Advantages And Disadvantages ◽  
Subpixel Accuracy ◽  
Low Costs ◽  
On The Road ◽  
Uav Images ◽  
The One ◽  
Research Centres

The UAV technology seems to be highly future-oriented due to its low costs as compared to traditional aerial images taken from classical photogrammetry aircrafts. The AGH University of Science and Technology in Cracow - Department of Geoinformation, Photogrammetry and Environmental Remote Sensing focuses mainly on geometry and radiometry of recorded images. Various scientific research centres all over the world have been conducting the relevant research for years. The paper presents selected aspects of processing digital images made with the UAV technology. It provides on a practical example a comparison between a digital image taken from an airborne (classical) height, and the one made from an UAV level. In his research the author of the paper is trying to find an answer to the question: to what extent does the UAV technology diverge today from classical photogrammetry, and what are the advantages and disadvantages of both methods? The flight plan was made over the Tokarnia Village Museum (more than 0.5 km<sup>2</sup>) for two separate flights: the first was made by an UAV - System FT-03A built by FlyTech Solution Ltd. The second was made with the use of a classical photogrammetric Cesna aircraft furnished with an airborne photogrammetric camera (Ultra Cam Eagle). Both sets of photographs were taken with pixel size of about 3 cm, in order to have reliable data allowing for both systems to be compared. The project has made aerotriangulation independently for the two flights. The DTM was generated automatically, and the last step was the generation of an orthophoto. The geometry of images was checked under the process of aerotriangulation. To compare the accuracy of these two flights, control and check points were used. RMSE were calculated. The radiometry was checked by a visual method and using the author's own algorithm for feature extraction (to define edges with subpixel accuracy). After initial pre-processing of data, the images were put together, and shown side by side. Buildings and strips on the road were selected from whole data for the comparison of edges and details. The details on UAV images were not worse than those on classical photogrammetric ones. One might suppose that geometrically they also were correct. The results of aerotriangulation prove these facts, too. Final results from aerotriangulation were on the level of RMS = 1 pixel (about 3 cm). In general it can be said that photographs from UAVs are not worse than classic ones. In the author's opinion, geometric and radiometric qualities are at a similar level for this kind of area (a small village). This is a very significant result as regards mapping. It means that UAV data can be used in mapping production.

Cloud computing as a means of forming the educational environment of a higher educational institution

2021 ◽  
pp. 59-66
Author(s):  
Natalia Ivanovna Popova ◽  
◽  
Artem Viktorovich Andronov ◽  
Aleksey Sergeevich Khomchenko ◽  
◽  
...  
Keyword(s):  
Cloud Computing ◽  
Educational Institution ◽  
Educational Environment ◽  
Educational Process ◽  
Cloud Services ◽  
Educational Services ◽  
Advantages And Disadvantages ◽  
Higher Educational ◽  
The One ◽  
Cloud Technologies

The article deals with the problems of the organization of the educational environment of higher educational institutions. The purpose of the article is to determine cloud computing as the most effective means of forming a unified educational environment of the university, providing a reliable organization of the educational process in the field of providing educational services in the “one window” mode in various social, political and economic conditions. Based on the analysis of modern platforms for organizing the educational environment and based on current trends in the IT market, Cloud Computing is currently one of the most promising areas. The article defines the essence of cloud computing, which is to provide hosting users with remote access to services, computing resources and applications over the Internet. Examples of the use of cloud technologies in the public sector and education are given. The main types of services provided by the Russian cloud services market (Saas and Iaas) are described. The implementation of the” National Cloud Platform O7″, developed by Rostelecom, is discussed in more detail. The advantages of organizing the educational environment with the help of cloud technologies are considered. Stand out. characteristic features of the Cloud Computing concept, various types of clouds are considered, their advantages and disadvantages. The organization of a unified educational environment of a higher educational institution through cloud computing is a promising direction that allows achieving high technological efficiency: while reducing the cost of purchasing special software and hardware, the quality and efficiency of the educational process in the conditions of digitalization of the economy significantly improves, and it also becomes possible to provide educational services in the “one window” mode, which is a priority of the Government of the Russian Federation.

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