scholarly journals Liquid Biphasic System: A Recent Bioseparation Technology

Processes ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 149 ◽  
Author(s):  
Kuan Shiong Khoo ◽  
Hui Yi Leong ◽  
Kit Wayne Chew ◽  
Jun-Wei Lim ◽  
Tau Chuan Ling ◽  
...  

A well-known bioseparation technique namely liquid biphasic system (LBS) has attracted many researchers’ interest for being an alternative bioseparation technology for various kinds of biomolecules. The present review begins with an in-depth discussion on the fundamental principle of LBS and this is followed by the discussion on further development of various phase-forming components in LBS. Additionally, the implementation of various advance technologies to the LBS that is beneficial towards the efficiency of LBS for the extraction, separation, and purification of biomolecules was discussed. The key parameters affecting the LBS were presented and evaluated. Moreover, future prospect and challenges were highlighted to be a useful guide for future development of LBS. The efforts presented in this review will provide an insight for future researches in liquid-liquid separation techniques.

2021 ◽  
Vol 251 ◽  
pp. 03020
Author(s):  
Sergey Gorbunov ◽  
Ernst Hellbär ◽  
Gian Michele Innocenti ◽  
Marian Ivanov ◽  
Maja Kabus ◽  
...  

The Time Projection Chamber (TPC) of the ALICE experiment at the CERN LHC was upgraded for Run 3 and Run 4. Readout chambers based on Gas Electron Multiplier (GEM) technology and a new readout scheme allow continuous data taking at the highest interaction rates expected in Pb-Pb collisions. Due to the absence of a gating grid system, a significant amount of ions created in the multiplication region is expected to enter the TPC drift volume and distort the uniform electric field that guides the electrons to the readout pads. Analytical calculations were considered to correct for space-charge distortion fluctuations but they proved to be too slow for the calibration and reconstruction workflow in Run 3. In this paper, we discuss a novel strategy developed by the ALICE Collaboration to perform distortion-fluctuation corrections with machine learning and convolutional neural network techniques. The results of preliminary studies are shown and the prospects for further development and optimization are also discussed.


2019 ◽  
Vol 46 (6) ◽  
pp. 761-783 ◽  
Author(s):  
Mohammad Hashemi Joo ◽  
Yuka Nishikawa ◽  
Krishnan Dandapani

Purpose The purpose of this paper is to recognize the benefits of the initial coin offering (ICO) as a way of raising funds and to present a detailed comparison between the ICO and the initial public offering to realize the future possibilities that this new funding method holds. Design/methodology/approach It is an exhaustive review of the ICO, the mechanism of crowdfunding, the blockchain technology behind it, benefits and current shortcomings of the ICO, and the potential future development of the ICO as a convenient and efficient way of raising capital. Findings ICOs have brought billions of dollars of funding to startups and projects worldwide in less than two years. Concurrently, many successful ICOs yielded extremely high returns to investors and believers of this new way of funding businesses. Research limitations/implications While the ICO is a revolutionary vehicle for business funding, it has raised concerns among users as well as potential investors about its risk and lack of regulation. The future of this innovative funding method highly depends on further development and placement of appropriate regulatory supervision, better understanding of risk and benefits and attaining the confidence of users. Originality/value This is a review of the advantages and drawbacks of the ICO. If the current fraud, market and cybersecurity risks can be mitigated and standardized regulations are developed, the ICO has a future to become an established way of capital funding or even replace the existing options, regardless of the size and age of companies.


2020 ◽  
Author(s):  
Stefaan Poedts

<p>The goal of the ESA project "Virtual Space Weather Modelling Centre - Part 3" (2019-2021) is to further develop the Virtual Space Weather Modelling Centre (VSWMC), building on the Part 2 prototype system and focusing on the interaction with the ESA SSA SWE system. A first, limited version went operational in May 2019 under the H-ESC umbrella on the ESA SSA SWE Portal. The objective and scopes of this new project include: the efficient integration of <strong>new models</strong> and <strong>new model couplings</strong>, including daily automated<strong> end-to-end (Sun to Earth) simulations, </strong>the further development and wider use of the <strong>coupling toolkit</strong>  and <strong>front-end GUI, </strong>making the <strong>operational system more robust and user-friendly.</strong> The VSWMC-Part 3 project started on 1 October 2019.</p><p>EUHFORIA (‘European heliospheric forecasting information asset’) is integrated in the VSWMC and will be upgraded with alternative coronal models (Multi-VP and Wind-Predict) and flux-rope CME models, and new couplings will be made available, e.g. to more advanced magnetospheric models and radiation belt models, geo-effects models, and even SEP models. The first results will be discussed and put into perspective.</p>


2000 ◽  
Vol 12 (3) ◽  
pp. 254-260 ◽  
Author(s):  
Toshiro Noritsugu ◽  
◽  
Daijyu Kaneshiro ◽  
Takashi Inoue

The manipulation of fragile and shapeless objects requires an actuator with enough flexibility and safety not to injure manipulated objects. To cope with such requirements, soft actuators have been developed, most of which utilize elastic deformation of a rubber tube or balloon caused by compressed air pressure. Such a pneumatic rubber actuator is expected to be effectively used as a flexible and friendly soft actuator in various fields. In this study, to realize a flexible pneumatic carrier system, a soft planar actuator using rubber balls has been developed assuming that the actuator directly contacts carried objects. This paper describes a fundamental principle of operation, a control method and experimental results. Additionally, a small sized soft planar actuator made of silicone rubber is described. The results show the effectiveness of the proposed actuator mechanism.


2001 ◽  
Vol 89 (11-12) ◽  
Author(s):  
Marin Ayranov ◽  
K. Wacker ◽  
Urs Krähenbühl

The separation of uranium and thorium from complex matrixes such as marine sediments using solvent extraction and determination by means of Photon-Electron Rejecting Liquid Alpha Spectrometry (PERALS®) has successfully been performed. Two extraction schemes, using TOPO and HDEHP, respectively, were compared for the separation of uranium and thorium from the matrix components. The results show recoveries between 73 and 92% for


2014 ◽  
Vol 940 ◽  
pp. 205-208
Author(s):  
Jian Xin Wang ◽  
Xian Qing Cao ◽  
Qi Ming Wu

Developments of products and technologies always follow certain objective law and the same objective law can be applied in different technical fields. the innovation processes of any products follow a law, the development of all technical innovation is toward maximum function. By applying some technical evolution paths, this paper analyses the technical development process of Converter Tilting Machines and forecasts the future development. The evolutionary paths of converter tilting mechanism has been analyzed by using TRIZ Theory, and, the development of Converter Tilting Machine has been forecasted. According to the path toward flexibility, we can forecast that Converter Tilting Machine can be driven by Filed force.


2014 ◽  
Vol 7 (1) ◽  
Author(s):  
Evica Delova-Jolevska ◽  
Ilija Andovski

Abstract: The aim of this paper is to elaborate the importance of service sector and how its  future development  will affect the banking industry in the Republic of Macedonia. We live in a service society, where services sector represents more than two-thirds of economic activity and four-fifths of growth in recent years in OECD countries. This trend is evident in Macedonia also, where the service sector represents around 60% from the economic activity. Stil, because of the positive correlation with the economic development, further development will result with growth of the service sector. Further liberalization, removing product market barriers still limiting competition in various sub-sectors, allowing more FDI are factors that are indicated by experts that can contribute for further development of the service sector.Regarding banking industry in  Macedonia, service sector has the biggest share in the credit portfolio. Especialy this is due of the high exposure towards trade.Comparative analysis with developed countries shows that the share of exposure towards service sector is greather in Macedonia. This is mainly due of the lower risk of this credit portfolio, whose average riskiness is below the industry sector and agriculture.Also, in deficiency of strong industrial sector who can export its goods, Macedonian banks are turned towards wholesale and retail trade sectors. So it is expected with growth of GDP per capita in future banks to increase the loan portfolio of industry and in the same time to decrease the share of trade sector portfolio in total service portfolio.


2021 ◽  
Author(s):  
◽  
Melissa Bryant

<p>Ngā Ūpoko Tukutuku/the Māori Subject Headings (MSH) were released in 2006, with the aim of “provid[ing] a structured path to subjects that Māori customers can…use to find material in libraries…using terms familiar to Māori and arranged in a hierarchy that reflects the Māori view of the world”. The project is a world leader and internationally well-regarded, but very little literature has been published evaluating the uptake and use of the MSH.  I talked with staff in wānanga, university, public, and special libraries, to explore how research libraries are applying the MSH and offering the MSH to their users, when adding metadata, providing reference and research services, or supporting library users to search independently.  Libraries employed diverse approaches tailored to their specific users, but participants consistently emphasised the importance of the MSH, advocated for further development of the thesaurus, and hoped for more training and information sharing between libraries.  Results are discussed in terms of four questions - What is working well? What could work better? What are the benefits of this work? What further questions do we need to answer?  Suggestions for further research include broader assessment of the actual and potential uptake of the MSH in libraries and other memory institutions, discussion with library users, and consideration of the future development of the MSH.</p>


2021 ◽  
Author(s):  
◽  
Melissa Bryant

<p>Ngā Ūpoko Tukutuku/the Māori Subject Headings (MSH) were released in 2006, with the aim of “provid[ing] a structured path to subjects that Māori customers can…use to find material in libraries…using terms familiar to Māori and arranged in a hierarchy that reflects the Māori view of the world”. The project is a world leader and internationally well-regarded, but very little literature has been published evaluating the uptake and use of the MSH.  I talked with staff in wānanga, university, public, and special libraries, to explore how research libraries are applying the MSH and offering the MSH to their users, when adding metadata, providing reference and research services, or supporting library users to search independently.  Libraries employed diverse approaches tailored to their specific users, but participants consistently emphasised the importance of the MSH, advocated for further development of the thesaurus, and hoped for more training and information sharing between libraries.  Results are discussed in terms of four questions - What is working well? What could work better? What are the benefits of this work? What further questions do we need to answer?  Suggestions for further research include broader assessment of the actual and potential uptake of the MSH in libraries and other memory institutions, discussion with library users, and consideration of the future development of the MSH.</p>


Processes ◽  
2019 ◽  
Vol 7 (1) ◽  
pp. 36 ◽  
Author(s):  
Ilaria Zambon ◽  
Massimo Cecchini ◽  
Gianluca Egidi ◽  
Maria Grazia Saporito ◽  
Andrea Colantoni

The present review retraces the steps of the industrial and agriculture revolution that have taken place up to the present day, giving ideas and considerations for the future. This paper analyses the specific challenges facing agriculture along the farming supply chain to permit the operative implementation of Industry 4.0 guidelines. The subsequent scientific value is an investigation of how Industry 4.0 approaches can be improved and be pertinent to the agricultural sector. However, industry is progressing at a much faster rate than agriculture. In fact, already today experts talk about Industry 5.0. On the other hand, the 4.0 revolution in agriculture is still limited to a few innovative firms. For this reason, this work deals with how technological development affects different sectors (industry and agriculture) in different ways. In this innovative background, despite the advantages of industry or agriculture 4.0 for large enterprises, small- and medium-sized enterprises (SMEs) often face complications in such innovative processes due to the continuous development in innovations and technologies. Policy makers should propose strategies, calls for proposals with aim of supporting SMEs to invest on these technologies and making them more competitive in the marketplace.


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