scholarly journals Show Me the Money! Process Modeling in Pharma from the Investor’s Point of View

Processes ◽  
2019 ◽  
Vol 7 (9) ◽  
pp. 596 ◽  
Author(s):  
Varsakelis ◽  
Dessoy ◽  
von Stosch ◽  
Pysik
Keyword(s):  
Diffusion Of Innovation ◽  
Process Modeling ◽  
Process Development ◽  
Flow Analysis ◽  
Point Of View ◽  
Expected Returns ◽  
Discounted Cash Flow ◽  
Investment Evaluation ◽  
Process Framework ◽  
And Diffusion

Process modeling in pharma is gradually gaining momentum in process development but budget restrictions are growing. We first examine whether and how current practices rationalize within a decision process framework with a fictitious investor facing a decision problem subject to incomplete information. We then develop an algorithmic procedure for investment evaluation on both monetary and diffusion-of-innovation fronts. Our methodology builds upon discounted cash flow analysis and Bayesian inference and utilizes the Rogers diffusion of innovation paradigm for computing lower expected returns. We also introduce a set of intangible metrics for quantifying the level of diffusion of process modeling within an organization.

scholarly journals Frugal Knowledge Sharing for Frugal Innovation Diffusion in Africa

2021 ◽  
Vol 29 (6) ◽  
pp. 1-23
Author(s):  
Getachew H. Mengesha ◽  
Richard Thomas Watson ◽  
Solomon Negash
Keyword(s):  
Social Capital ◽  
Knowledge Sharing ◽  
Innovation Diffusion ◽  
Diffusion Of Innovation ◽  
Point Of View ◽  
Frugal Innovation ◽  
African Context ◽  
And Diffusion ◽  
Frugal Innovations ◽  
The Church

This study explores mechanisms of frugal knowledge sharing for frugal innovation diffusion drawing upon concepts from social capital and diffusion of innovation theories. Three frugal innovations projects from Uganda, Malawi, and Ethiopia are used to undertake a preliminary appraisal of a proposed theoretical model. The study identifies a frugal knowledge sharing mechanism based on “The Church lady model”. From a practice perspective, the study informs how to leverage social capital to facilitate frugal knowledge sharing. Insights drawn from this study cover the surrounding network structure, mode of communication, frugal knowledge sharing modalities, and the opportunity for combination and exchange to spark varied frugal IS innovation projects. From a research point of view, it serves as a basis for frugal knowledge management for frugal innovation diffusion in an African context.

scholarly journals Impedance Matching-Based Power Flow Analysis for UPQC in Three-Phase Four-Wire Systems

Energies ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2702
Author(s):  
Xiaojun Zhao ◽  
Xiuhui Chai ◽  
Xiaoqiang Guo ◽  
Ahmad Waseem ◽  
Xiaohuan Wang ◽  
...  
Keyword(s):  
Power Flow ◽  
Control Strategies ◽  
Impedance Matching ◽  
Flow Analysis ◽  
Point Of View ◽  
Impedance Model ◽  
Power Flow Analysis ◽  
Three Phase ◽  
System Node ◽  
Power Quality Conditioner

Different from the extant power flow analysis methods, this paper discusses the power flows for the unified power quality conditioner (UPQC) in three-phase four-wire systems from the point of view of impedance matching. To this end, combined with the designed control strategies, the establishing method of the UPQC impedance model is presented, and on this basis, the UPQC system can be equivalent to an adjustable impedance model. After that, a concept of impedance matching is introduced into this impedance model to study the operation principle for the UPQC system, i.e., how the system changes its operation states and power flow under the grid voltage variations through discussing the matching relationships among node impedances. In this way, the nodes of the series and parallel converter are matched into two sets of impedances in opposite directions, which mean that one converter operates in rectifier state to draw the energy and the other one operates in inverter state to transmit the energy. Consequently, no matter what grid voltages change, the system node impedances are dynamically matched to ensure that output equivalent impedances are always equal to load impedances, so as to realize impedance and power balances of the UPQC system. Finally, the correctness of the impedance matching-based power flow analysis is validated by the experimental results.

scholarly journals Intercultural Competencies for Fostering Technology-Mediated Collaboration in Developing Countries

2021 ◽  
Vol 13 (14) ◽  
pp. 7790
Author(s):  
Albert Kampermann ◽  
Raymond Opdenakker ◽  
Beatrice Van der Heijden ◽  
Joost Bücker
Keyword(s):  
Developing Countries ◽  
Point Of View ◽  
Early Years ◽  
Ict Skills ◽  
Intercultural Competencies ◽  
Information And Communication ◽  
Key Competencies ◽  
Different Cultures ◽  
And Diffusion ◽  
Successful Technology

With the rapid global spread and application of Information and Communication Technology (ICT), the question is whether every culture makes similar use of the ideology that often underlies its creators’ design. ICT applications are designed with underlying beliefs or principles about e.g., work, communication, and individuality. These beliefs or principles are invisible and hidden in software and, as such, in many instances not recognized by users in other cultures. These hidden principles might even frustrate the understanding, use, knowledge-sharing, and e-collaboration between people from different cultures. In this article, we aim to explore, from a historical point of view, the early years of adaptation of ICT in developing countries, and we will highlight the importance of the use of intercultural (ICT-)skills to learn to recognize cultural differences from a relationship-based definition in technology-mediated collaboration. A semi-systematic or narrative review approach is used that is particularly suitable for topics that have been conceptualized differently. Our review firstly summarizes and categorizes the cultural factors impacting the adaptation and diffusion of ICT, especially in developing countries, and investigates which factors could hinder and/or facilitate the collaboration with other countries. Secondly, the findings of a thorough comparison between different intercultural competencies’ frameworks indicate that intercultural competencies show a combination of motivation, knowledge (-management), and skills, which are key competencies in the light of successful technology-mediated collaboration.

INFINITI HR – professional employer organizations

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Susan White ◽  
Karen Hallows
Keyword(s):  
Financial Analysis ◽  
Flow Analysis ◽  
Capital Budgeting ◽  
Discounted Cash Flow ◽  
Content Type ◽  
Analysis And Evaluation ◽  
Academic Level ◽  
Course Of Action ◽  
Basic Capital ◽  
Current Events

Theoretical basis Students need to know basic capital budgeting techniques to value INFINITI and its competitors. Issues include how to: handle taxes in a discounted cash flow analysis when valuing an S Corp. where incentives depend on current (known) and future (unknown) tax provisions; value a firm using comparable multiples analysis and transactions data; assess the costs and benefits of acquiring a firm versus being acquired; and analyze an industry and perform a ratio and financial statement analysis. Research methodology The case information was obtained through interviews with co-founder Mark Schwaiger. In addition, the authors researched industry and comparable company data, along with current events relating to the professional employer organization (PEO). Financial data was obtained from the owners and competitor data was obtained from Thomson One and Bloomberg. Case overview/synopsis INFINITI HR was a PEO providing comprehensive human resources to their clients. Co-founders Scott Smrkovski and Mark Schwaiger were at a crossroads at the end of 2015 trying to determine the best course of action to take with their company to grow and prosper. One option was for INFINITI to be acquired by a larger company and the second option was for INFINITI acquire a smaller company. In this case, students have the opportunity to do a financial analysis and evaluation of INFINITI and its competitors to determine which option is the best. Complexity academic level This case is intended for an advanced undergraduate or an MBA corporate finance class.

Pasture systems to improve productivity of sheep in south-western Victoria 2. Animal production from ewes and lambs

2011 ◽  
Vol 51 (11) ◽  
pp. 982 ◽  
Author(s):  
Geoffrey Saul ◽  
Gavin Kearney ◽  
Dion Borg
Keyword(s):  
Flow Analysis ◽  
Subterranean Clover ◽  
Supplementary Feeding ◽  
Stocking Rate ◽  
Discounted Cash Flow ◽  
Condition Score ◽  
Western Victoria ◽  
Breakeven Point ◽  
Gross Margins ◽  
On Farm

Two pasture systems (Typical, Upgraded) were compared at five on-farm sites across south-western Victoria between 1990 and 1996. The Typical pasture treatment mimicked the pastures common in the region, with volunteer annual-based species fertilised with ~5 kg/ha.year phosphorus (P). The Upgraded pasture treatment was sown to phalaris, perennial ryegrass and subterranean clover using cultivars recommended for the particular area. Higher rates of fertiliser (13–25 kg/ha.year P) plus other nutrients were applied. Both pastures were set-stocked with breeding ewes. The stocking rate on the Typical treatments was based on normal farm practice. Initially, the stocking rate of the Upgraded pastures was 15% higher than the Typical pastures and increased over time depending if the ewes in the Upgraded pastures were heavier than those in the Typical pastures. Measurements included pasture growth, composition and persistence, ewe stocking rates, ewe and lamb liveweights and condition scores, lambing, marking and weaning percentages, fleece characteristics and supplementary feeding. Over the 6 years, the average carrying capacity of the Upgraded pastures was 18.0 DSE (Dry Sheep Equivalents)/ha compared with 10.2 DSE/ha on the Typical pastures (P < 0.001). As well, the ewes on the Upgraded pastures were 2–3 kg heavier (P < 0.001) and 0.3 condition score higher (P < 0.001) than those on the Typical pastures. Ewes grazing the Upgraded pastures cut significantly more wool per head (4.8 versus 4.5 kg) of higher micron wool (23.1 versus 22.6 um, P < 0.001) but with similar yield and strength. There was no difference in the supplementary feeding required on the treatments. Ewes grazing Upgraded pastures had significantly higher lambing (116 versus 102%), marking (86 versus 81%) and weaning percentages (84 versus 79%) and weaned significantly heavier lambs (23.6 versus 22.6 kg) than those on Typical pastures. There was less feed on offer (P < 0.05) in the Upgraded pastures compared with the Typical pastures in autumn–winter but similar or higher levels in spring and summer. Gross margins using current costs and prices were $20 and $24/DSE for the Typical and Upgraded pastures, respectively. These values were used in a discounted cash flow analysis to determine the long-term benefits of the treatments. Assuming a 12-year life for the pasture, the internal rate of return was 27% with the breakeven point in Year 7. Treatment and ewe condition score significantly influenced lambing percentage with ewes in condition score 3.0 at joining having a lambing percentage of 111% compared with 95% if at condition score 2.3. Irrespective of condition score, ewes grazing Upgraded pastures had a 7% higher lambing percentage than those grazing the Typical pastures. Ewe condition score and lambing time significantly affected weaning weight. Lambs born to ewes in condition score 2.3 during pregnancy and lambing in autumn, reached only 32% of mature ewe liveweight at weaning whereas lambs from ewes at condition score 3.0 achieved 51% of mature weight by weaning.

scholarly journals Financial Feasibility of Investing in Smallholder Cow-Calf Cooperatives in Baluran National Park

Agro Ekonomi ◽  
2017 ◽  
Vol 28 (1) ◽  
pp. 126
Author(s):  
Mark Rademaker ◽  
Any Suryantini ◽  
Jangkung Handoyo Mulyo
Keyword(s):  
National Park ◽  
Flow Analysis ◽  
Livestock Grazing ◽  
Farm Labor ◽  
Conservation Priorities ◽  
Conservation Areas ◽  
Discounted Cash Flow ◽  
Management Plans ◽  
Cow Calf ◽  
The Government

Livestock grazing is a major driver of human-wildlife confl ict in conservation areas. Currently, it is estimated that 3000 heads of cattle illegally grazing within Baluran National Park (BNP) in East Java. The recent research has suggested the potential of livestock system intensifi cation to reduce land-use and conflict through conservation priorities. The research goal was to investigate the fi nancial feasibility of starting intensive cow-calf cooperatives by smallholders in the BNP area. Data were collected using Farm surveys in a Criterion sampling design. Optimal herd management plans were generated using whole farm Linear Programming and fi nancial feasibility was assessed using Discounted cash-flow analysis and debt-servicing capabilities. Investment lifetime was set at 15 years and four alternative varieties of cattle were taken from Bali, Peranakan Ongole, Limousin and Simmental. Results show that investing in all varieties represents a positive investment opportunity. Bali cattle obtaining the highest NPV ($53.769), IRR (14,25%) and B/C ratio (1,13). Farmer income can be increased by 163% by combining additional Off-farm labor. However, debt servicing capabilities of cow-calf cooperative activities showed that the loan principal can only be repaid in the 10th year instead of the maximum eight years set by the government cow-calf credit scheme. We urge the government to reconsider either the grace period or the repayment time of the credit scheme to better fit the cash-fl ow characteristics of cow-calf enterprises.

Film Use to Promote Understanding in Change and Diffusion of Innovation

2016 ◽  
Vol 30 (3) ◽  
pp. 277-293
Author(s):  
Douglas A. Wilson ◽  
Victoria Raish ◽  
Alison Carr-Chellman
Keyword(s):  
Diffusion Of Innovation ◽  
And Diffusion
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