scholarly journals Biomimetically Reinforced Polyvinyl Alcohol-Based Hybrid Scaffolds for Cartilage Tissue Engineering

Polymers ◽  
2017 ◽  
Vol 9 (12) ◽  
pp. 655 ◽  
Author(s):  
Hwan Kim ◽  
Yunsup Lee ◽  
Yunhye Kim ◽  
Yongsung Hwang ◽  
Nathaniel Hwang
Author(s):  
Ming-You Shie ◽  
Wen-Ching Chang ◽  
Li-Ju Wei ◽  
Yu-Hsin Huang ◽  
Chien-Han Chen ◽  
...  

Diseases in articular cartilages have affected millions of people globally. Although the biochemical and cellular composition of articular cartilages is relatively simple, there is the limitation in self-repair ability of cartilage. Therefore, developing the strategies for cartilage repair is very important. Here, we reported a new manufacturing process of water-based polyurethane based photosensitive materials with hyaluronic acid and applied the materials for 3D printed customized cartilage scaffolds. The scaffold has high cytocompatibility and is one that closely mimics the mechanical properties of articular cartilages. It is suitable for culturing human Wharton's jelly mesenchymal stem cells (hWJMSCs) and the cells showed an excellent chondrogenic differentiation capacity. We consider that the 3D printing hybrid scaffolds may have potential in customized tissue engineering and facilitate the development of cartilage tissue engineering.


2013 ◽  
Vol 25 (4) ◽  
pp. 1129-1136 ◽  
Author(s):  
Anne-Marie Haaparanta ◽  
Elina Järvinen ◽  
Ibrahim Fatih Cengiz ◽  
Ville Ellä ◽  
Harri T. Kokkonen ◽  
...  

2007 ◽  
Vol 15 ◽  
pp. B117
Author(s):  
J. Schagemann ◽  
H. Chung ◽  
J.J. Stone ◽  
E. Mrosek ◽  
J.S. Fitzsimmons ◽  
...  

2013 ◽  
Vol 24 (10) ◽  
pp. 2449-2460 ◽  
Author(s):  
Mohammad Ali Shokrgozar ◽  
Shahin Bonakdar ◽  
Mohammad Mehdi Dehghan ◽  
Shahriar Hojjati Emami ◽  
Leila Montazeri ◽  
...  

2020 ◽  
Vol 31 (9) ◽  
pp. 1179-1198 ◽  
Author(s):  
Weiwei Lan ◽  
Mengjie Xu ◽  
Xiumei Zhang ◽  
Liqin Zhao ◽  
Di Huang ◽  
...  

2009 ◽  
Vol 9999A ◽  
pp. NA-NA ◽  
Author(s):  
J. C. Schagemann ◽  
H. W. Chung ◽  
E.H. Mrosek ◽  
J.J. Stone ◽  
J.S. Fitzsimmons ◽  
...  

Biomaterials ◽  
2010 ◽  
Vol 31 (8) ◽  
pp. 2141-2152 ◽  
Author(s):  
Wenda Dai ◽  
Naoki Kawazoe ◽  
Xiaoting Lin ◽  
Jian Dong ◽  
Guoping Chen

2018 ◽  
Vol 762 ◽  
pp. 54-58 ◽  
Author(s):  
Anna Timofejeva ◽  
Dagnija Loca

Composite hydrogels on the basis of hydroxyapatite (HAp) and polyvinyl alcohol (PVA) has been proposed as a promising materials for bone and cartilage tissue engineering. HAp/PVA composite hydrogels with phase ratio 50:50wt% and 70:30wt% were obtained via in situ wet chemical precipitation technique in combination with the freeze-thawing approach. The XRD studies of sintered products revealed that HAp/PVA composite hydrogels synthesized from PVA with degree of hydrolysis (DH) 98% and molecular weights (MW) 25 kDa and 78 kDa are more suitable for biomedical purposes due to the formation of stoichiometric HAp. Swelling studies indicated that HAp/PVA 50:50 (78 kDa, 88% and 98%) hydrogels after 24h of immersion swell ~4.25-6.5 times less than identical samples with phase composition of 70:30wt%, which is accounted to different number of intermolecular hydrogen bonds formed. After 16 subsequent freeze-thawing cycles (FTC), HAp/PVA 50:50 (78 kDa, 88% and 98%) hydrogels contain ~1.2 times higher content of crosslinked PVA than HAp/PVA 70:30 (78 kDa, 88% and 98%) hydrogel samples.


2020 ◽  
Vol 30 (5) ◽  
pp. 642-650 ◽  
Author(s):  
Nur Rofiqoh Eviana Putri ◽  
Xiuhui Wang ◽  
Ying Chen ◽  
Xiaomeng Li ◽  
Naoki Kawazoe ◽  
...  

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