scholarly journals 3D Biofabrication of Thermoplastic Polyurethane (TPU)/Poly-l-lactic Acid (PLLA) Electrospun Nanofibers Containing Maghemite (γ-Fe2O3) for Tissue Engineering Aortic Heart Valve

Polymers ◽  
2017 ◽  
Vol 9 (11) ◽  
pp. 584 ◽  
Author(s):  
Ehsan Fallahiarezoudar ◽  
Mohaddeseh Ahmadipourroudposht ◽  
Noordin Mohd Yusof ◽  
Ani Idris ◽  
Nor Hasrul Akhmal Ngadiman
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Heart Valve ◽  
Thermoplastic Polyurethane ◽  
Electrospun Nanofibers ◽  
Aortic Heart Valve

Characterizing Nanoscale Topography of the Aortic Heart Valve Basement Membrane for Tissue Engineering Heart Valve Scaffold Design

2006 ◽  
Vol 0 (0) ◽  
pp. 060224115912001
Author(s):  
Sarah Brody ◽  
Thapasimuthu Anilkumar ◽  
Sara Liliensiek ◽  
Julie A. Last ◽  
Christopher J. Murphy ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Basement Membrane ◽  
Heart Valve ◽  
Scaffold Design ◽  
Aortic Heart Valve ◽  
Nanoscale Topography ◽  
Tissue Engineering Heart Valve

The Role of Collagen Cross-Links in Biomechanical Behavior of Human Aortic Heart Valve Leaflets—Relevance for Tissue Engineering

2007 ◽  
Vol 13 (7) ◽  
pp. 1501-1511 ◽  
Author(s):  
Angelique Balguid ◽  
Mirjam P. Rubbens ◽  
Anita Mol ◽  
Ruud A. Bank ◽  
Ad J.J.C. Bogers ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Heart Valve ◽  
Aortic Heart Valve ◽  
Biomechanical Behavior ◽  
Cross Links

Characterization of maghemite (γ-Fe2O3)-loaded poly-l-lactic acid/thermoplastic polyurethane electrospun mats for soft tissue engineering

2016 ◽  
Vol 51 (18) ◽  
pp. 8361-8381 ◽  
Author(s):  
Ehsan Fallahiarezoudar ◽  
Mohaddeseh Ahmadipourroudposht ◽  
Ani Idris ◽  
Noordin Mohd Yusof ◽  
Mohsen Marvibaigi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Soft Tissue ◽  
Thermoplastic Polyurethane ◽  
Soft Tissue Engineering

scholarly journals Characterizing Nanoscale Topography of the Aortic Heart Valve Basement Membrane for Tissue Engineering Heart Valve Scaffold Design

2006 ◽  
Vol 12 (2) ◽  
pp. 413-421 ◽  
Author(s):  
Sarah Brody ◽  
Thapasimuthu Anilkumar ◽  
Sara Liliensiek ◽  
Julie A. Last ◽  
Christopher J. Murphy ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Basement Membrane ◽  
Heart Valve ◽  
Scaffold Design ◽  
Aortic Heart Valve ◽  
Nanoscale Topography ◽  
Tissue Engineering Heart Valve

scholarly journals Fabrication, Characterization, and Cytotoxicity of Thermoplastic Polyurethane/Poly(lactic acid) Material Using Human Adipose Derived Mesenchymal Stromal Stem Cells (hASCs)

Polymers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1073 ◽  
Author(s):  
Anna Lis-Bartos ◽  
Agnieszka Smieszek ◽  
Kinga Frańczyk ◽  
Krzysztof Marycz
Keyword(s):  
Tissue Engineering ◽  
Lactic Acid ◽  
Thermoplastic Polyurethane ◽  
Tensile Tests ◽  
In Vitro Assays ◽  
Poly Lactic Acid ◽  
Scanning Calorimetry ◽  
Casting Technique ◽  
Wide Range

Thermoplastic polyurethane (TPU) and poly(lactic acid) are types of biocompatible and degradable synthetic polymers required for biomedical applications. Physically blended (TPU+PLA) tissue engineering matrices were produced via solvent casting technique. The following types of polymer blend were prepared: (TPU+PLA) 7:3, (TPU+PLA) 6:4, (TPU+PLA) 4:6, and (TPU+PLA) 3:7. Various methods were employed to characterize the properties of these polymers: surface properties such as morphology (scanning electron microscopy), wettability (goniometry), and roughness (profilometric analysis). Analyses of hydrophilic and hydrophobic properties, thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) of the obtained polymer blends were conducted. Tensile tests demonstrated that the blends exhibited a wide range of mechanical properties. Cytotoxicity of polymers was tested using human multipotent stromal cells derived from adipose tissue (hASC). In vitro assays revealed that (TPU+PLA) 3:7 matrices were the most cytocompatible biomaterials. Cells cultured on (TPU+PLA) 3:7 had proper morphology, growth pattern, and were distinguished by increased proliferative and metabolic activity. Additionally, it appeared that (TPU+PLA) 3:7 biomaterials showed antiapoptotic properties. hASC cultured on these matrices had reduced expression of Bax-α and increased expression of Bcl-2. This study demonstrated the feasibility of producing a biocompatible scaffold form based on (TPU+PLA) blends that have potential to be applied in tissue engineering.

Tissue engineering a functional aortic heart valve: an appraisal

2005 ◽  
Vol 1 (3) ◽  
pp. 405-411 ◽  
Author(s):  
Yos S Morsi ◽  
Ian Birchall
Keyword(s):  
Tissue Engineering ◽  
Heart Valve ◽  
Aortic Heart Valve
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