scholarly journals Keratin/Polyvinyl Alcohol Blend Films Cross-Linked by Dialdehyde Starch and Their Potential Application for Drug Release

Polymers ◽  
2015 ◽  
Vol 7 (3) ◽  
pp. 580-591 ◽  
Author(s):  
Yao Dou ◽  
Buning Zhang ◽  
Ming He ◽  
Guoqiang Yin ◽  
Yingde Cui ◽  
...  
2018 ◽  
Vol 39 (1) ◽  
pp. 35-47 ◽  
Author(s):  
Naman Jain ◽  
Vinay K. Singh ◽  
Sakshi Chauhan

Abstract The present study focuses on the fabrication and analyses of polyvinyl alcohol (PVA) based films blended with polymers, such as starch and protein. The aim is to improve the moisture absorption, solubility, mechanical and thermal properties of PVA by blending it with various polymers. The thermal cross-linking of the films has been studied by heating the films at 120°C for 4 h. The result shows that PVA was completely soluble in water, while post-blending solubility and moisture absorption of blended films decreased. The tensile strength of blended films was significantly higher (4%–29%) as compared to neat PVA, while thermally cross-linked films showed much higher strength (8%–174%). Blended films were characterized using Fourier transform infrared spectroscopy (FTIR) to confirm the formation of hydrogen bonds. Thermogravimetric analysis showed the increase in degradation temperature post-blending as compared to neat PVA. The viscoelastic behavior of the material as well as glass transition temperature was studied using dynamic mechanical analysis. Creep and recovery behavior were examined to study the effect of stress and temperature on creep strain. The biodegradability of the blended films was increased post-blending. This study showed that PVA based blend films can replace non-biodegradable plastics and hence are necessary for the development of environmentally friendly materials.


Nanomaterials ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 327 ◽  
Author(s):  
Shufang Wu ◽  
Xunjun Chen ◽  
Tiehu Li ◽  
Yingde Cui ◽  
Minghao Yi ◽  
...  

In this study, feather keratin/polyvinyl alcohol/tris(hydroxymethyl)aminomethane (FK/PVA/Tris) bionanocomposite films containing graphene oxide (GO) (0.5, 1, 2, and 3 wt%) or graphene (0.5, 1, 2, and 3 wt%) were prepared using a solvent casting method. The scanning electron microscopy results indicated that the dispersion of GO throughout the film matrix was better than that of graphene. The successful formation of new hydrogen bonds between the film matrix and GO was confirmed through the use of Fourier-transform infrared spectroscopy. The tensile strength, elastic modulus, and initial degradation temperature of the films increased, whereas the total soluble mass, water vapor permeability, oxygen permeability, and light transmittance decreased following GO or graphene incorporation. In summary, nanoblending is an effective method to promote the application of FK/PVA/Tris-based blend films in the packaging field.


2014 ◽  
Vol 216 ◽  
pp. 205-209
Author(s):  
Monica Cretan Stamate ◽  
Ciprian Stamate

The present paper aims to study the possibility to modify the properties of polyvinyl alcohol (pva) cryogels prepared in the presence of ketoprofen in order to replace the damaged articular cartilage. Articular cartilage is the most important part of articulation characterized by very low friction, high wear resistance, and poor regenerative qualities. Polyvinyl alcohol is a non-expensive polymer, versatile and adaptable to various needs, with exceptional properties such as water solubility, biocompatibility, non-toxicity and with capability to form hydrogels by chemical or physical methods. The aims of this paper are the synthesis, the physicochemical characterization and analysis of the tribological properties of pva cryogels for cartilage replacement and the introduction of new concept in medication by creating the cryogel like a controlled drug release system. The morphology of the cryogels, the interaction between the pva macromolecular chains and medicament has been studied by Scanning Electronic Microscopy. The gels swelling in physiologic ser have been monitored by gravimetric method in order to evidence the hydrophilic properties. The mechanical properties of the cryogels have been investigated by dynamic mechanical measurements. In conclusion, the biomaterial obtained provides good swelling properties, mechanical resistance and it is ideal for extended drug release implantable systems.


2017 ◽  
Vol 96 ◽  
pp. 518-523 ◽  
Author(s):  
Huafeng Tian ◽  
Jiaan Yan ◽  
A. Varada Rajulu ◽  
Aimin Xiang ◽  
Xiaogang Luo

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