scholarly journals A Review on Hydrogels with Photothermal Effect in Wound Healing and Bone Tissue Engineering

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2100
Author(s):  
Xu Zhang ◽  
Bowen Tan ◽  
Yanting Wu ◽  
Min Zhang ◽  
Jinfeng Liao
Keyword(s):  
Tissue Engineering ◽  
Wound Healing ◽  
Bone Regeneration ◽  
Controlled Drug Release ◽  
Multidrug Resistant ◽  
Future Application ◽  
Photothermal Effect ◽  
Resistant Bacteria ◽  
Promote Cell Proliferation ◽  
Recent Developments

Photothermal treatment (PTT) is a promising strategy to deal with multidrug-resistant bacteria infection and promote tissue regeneration. Previous studies demonstrated that hyperthermia can effectively inhibit the growth of bacteria, whereas mild heat can promote cell proliferation, further accelerating wound healing and bone regeneration. Especially, hydrogels with photothermal properties could achieve remotely controlled drug release. In this review, we introduce a photothermal agent hybrid in hydrogels for a photothermal effect. We also summarize the potential mechanisms of photothermal hydrogels regarding antibacterial action, angiogenesis, and osteogenesis. Furthermore, recent developments in photothermal hydrogels in wound healing and bone regeneration applications are introduced. Finally, future application of photothermal hydrogels is discussed. Hydrogels with photothermal effects provide a new direction for wound healing and bone regeneration, and this review will give a reference for the tissue engineering.

scholarly journals From Dermal Patch to Implants—Applications of Biocomposites in Living Tissues

Molecules ◽  
2020 ◽  
Vol 25 (3) ◽  
pp. 507
Author(s):  
Karolina Papera Valente ◽  
Alexandre Brolo ◽  
Afzal Suleman
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Wound Healing ◽  
Bone Regeneration ◽  
Dental Implants ◽  
Biomedical Engineering ◽  
Superior Mechanical Properties ◽  
Low Toxicity ◽  
Living Tissues ◽  
Dermal Patch

Composites are composed of two or more materials, displaying enhanced performance and superior mechanical properties when compared to their individual components. The use of biocompatible materials has created a new category of biocomposites. Biocomposites can be applied to living tissues due to low toxicity, biodegradability and high biocompatibility. This review summarizes recent applications of biocomposite materials in the field of biomedical engineering, focusing on four areas—bone regeneration, orthopedic/dental implants, wound healing and tissue engineering.

Mathematical Modeling in Wound Healing, Bone Regeneration and Tissue Engineering

2010 ◽  
Vol 58 (4) ◽  
pp. 355-367 ◽  
Author(s):  
Liesbet Geris ◽  
Alf Gerisch ◽  
Richard C. Schugart
Keyword(s):  
Mathematical Modeling ◽  
Tissue Engineering ◽  
Wound Healing ◽  
Bone Regeneration ◽  
Healing Bone

Polysaccharide‐Peptide Cryogels for Multidrug‐Resistant‐Bacteria Infected Wound Healing and Hemostasis

2019 ◽  
Vol 9 (3) ◽  
pp. 1901041 ◽  
Author(s):  
Sen Hou ◽  
Yuanyuan Liu ◽  
Fang Feng ◽  
Jin Zhou ◽  
Xinxing Feng ◽  
...  
Keyword(s):  
Wound Healing ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Infected Wound ◽  
Multidrug Resistant Bacteria

scholarly journals Negative-Pressure Wound Therapy in a Patient with Osteomyelitis Caused by Multidrug-Resistant Bacterial Infection: A Case Report

2021 ◽  
Vol 17 (3) ◽  
pp. 193-197
Author(s):  
Taekeun Yoon ◽  
Sang Wha Kim
Keyword(s):  
Wound Healing ◽  
Negative Pressure ◽  
Bacterial Infections ◽  
Negative Pressure Wound Therapy ◽  
Bacterial Load ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Wound Therapy ◽  
Subsequent Formation ◽  
Subcutaneous Tunneling

Uncontrolled infection, especially with multidrug-resistant bacteria, may significantly inhibit wound healing. Although negative-pressure wound therapy can help prevent infection, it is contraindicated in patients with untreated infections, including osteomyelitis. Here, we report successful wound healing by negative-pressure wound therapy in a patient with refractory osteomyelitis due to multiple multidrug-resistant bacterial infections. Soft tissue infection and osteomyelitis progressed deeply through subcutaneous tunneling; hence, bacteria were not excreted from the affected area. Negative-pressure wound therapy reduced the bacterial load and resolved the patient’s condition. Healing by secondary intention progressed with subsequent formation of granulation tissue. Despite recommendations against negative-pressure wound therapy in patients with osteomyelitis, this study highlights the application of the technique for infection control in patients with multidrug-resistant bacterial infections and osteomyelitis.

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