scholarly journals Polymeric Drug Delivery Systems Bearing Cholesterol Moieties: A Review

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2620
Author(s):  
Paweł Misiak ◽  
Karolina H. Markiewicz ◽  
Dawid Szymczuk ◽  
Agnieszka Z. Wilczewska

This review aims to provide an overview of polymers comprising cholesterol moiety/ies designed to be used in drug delivery. Over the last two decades, there have been many papers published in this field, which are summarized in this review. The primary focus of this article is on the methods of synthesis of polymers bearing cholesterol in the main chain or as side chains. The data related to the composition, molecular weight, and molecular weight distribution of polymers are presented. Moreover, other aspects, such as forms of carriers, types of encapsulated drugs, encapsulation efficiency and capacity, are also included.

2021 ◽  
Vol 173 ◽  
pp. 349-373
Author(s):  
Sedigheh Borandeh ◽  
Bas van Bochove ◽  
Arun Teotia ◽  
Jukka Seppälä

Author(s):  
Naveed Ahmed ◽  
C.E. Mora-Huertas ◽  
Chiraz Jaafar-Maalej ◽  
Hatem Fessi ◽  
Abdelhamid Elaissari

2019 ◽  
Vol 890 ◽  
pp. 324-339
Author(s):  
Geetha B. Heggannavar ◽  
Divya Achari ◽  
Cristiana Fernandes ◽  
Geoffrey R. Mitchell ◽  
Pedro Morouço ◽  
...  

The most important components of living cells such as carbohydrates, proteins and nucleic acids are the polymeric molecules. Nature utilizes polymers both as constructive elements and as a part of the complicated cell machinery of living things. The rapid advancement in biomedical research has led to many creative applications for biocompatible polymers. With the development of newer and more potent drugs, a parallel expansion in more sophisticated drug delivery systems becomes mandatory. Smart polymeric drug-delivery systems have the ability to respond to environmental changes and consequently, alter their properties reversibly enabling an efficient and safe drug delivery. This review comprehensively discusses various aspects of these polymers classified in different categories as per the type of stimulus.


2006 ◽  
Vol 101 (5) ◽  
pp. 3192-3201 ◽  
Author(s):  
Martin Hrubý ◽  
Tomáš Etrych ◽  
Jan Kučka ◽  
Michaela Forsterová ◽  
Karel Ulbrich

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