scholarly journals Utility of Zinc Oxide Nanoparticles Catalytic Activity in the Electrochemical Determination of Minocycline Hydrochloride

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2505
Author(s):  
Amal M. Al-Mohaimeed ◽  
Wedad A. Al-Onazi ◽  
Maha F. El-Tohamy
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Electrochemical Determination ◽  
Electrochemical Sensing ◽  
Oxide Nanoparticles ◽  
Regression Equations ◽  
Minocycline Hydrochloride

The current work described the synthesis and characterization of zinc oxide nanoparticles (ZnONPs) and their electrocatalytic activity in the determination of minocycline hydrochloride (MCL). The unique features of metal oxide nanoparticles such as zinc oxide encourage the researchers to investigate the activity of metal oxide nanoparticles as remarkable semiconductor materials active in the electrochemical sensing determination. Herein, the suggested study displayed a comparative determination of minocycline hydrochloride using two conventional and modified ZnONPs-coated wire sensors. The recorded results showed the linear behavior of the enriched ZnONPs sensor over the 1.0 × 10−10–1.0 × 10−2 mol L−1 with respect to 1.0 × 10−6–1.0 × 10−2 mol L−1 for the conventional sensor. The two sensors are working in the pH range of 3–5 with regression equations EmV = (53.2 ± 0.5) log [MCL] + 448.8 and EmV = (58.7 ± 0.2) log [MCL] + 617.76 for conventional and enriched ZnONPs, respectively. The correlation coefficients were 0.9995 and 0.9998 for the previously mentioned sensors, respectively. The validity of the suggested analytical method was evaluated according to the recommended guidelines for methodology and drug analysis. The developed sensors were also used in the quantification of MCL in commercial formulations.

Preparation of zinc oxide nanoparticles using punica granatum and elettaria cardamomum fruit extract and determining its antibacterial activity against lactobacillus

2020 ◽  
Vol 11 (3) ◽  
pp. 3372-3376
Author(s):  
Shilpa Merlyn Jose ◽  
Hannah.R ◽  
Rajeshkumar S
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Punica Granatum ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Fruit Extract ◽  
Elettaria Cardamomum

To determine the antibacterial activity of Zinc oxide nanoparticles synthesised using Punica granatum and Elettaria cardamomum fruit extract against Lactobacillus. Punica granatum and Elettaria cardamomum have been known for their antimicrobial, antioxidant and anti-inflammatory activity. The phytochemicals present in these fruits have experimented for the preparation of various metal and metal oxide nanoparticles. Zinc oxide is a widely used metal oxide nanoparticle known for its good antimicrobial activity against a host of microbes. The current study was conducted to determine its effect against Lactobacillus, a bacteria known for its role in the progression of dental caries. Preparation of fruit extract mediated zinc oxide nanoparticles. Determining the characteristics of the nanoparticles using UV spectroscopy and SEM. Analysing the activity of these nanoparticles against Lactobacillus using agar well diffusion method. The zone of inhibition increased if the concentration of the fruit mediated zinc oxide nanoparticles increased. But it was incomparable to the standards. Hence, further studies need to be conducted using different concentration of Punica granatum and Elettaria cardamomum to determine the optimum fruit extract required for the preparation of the nanoparticles. The resultant nanoparticles can be used as an effective antimicrobial agent against Lactobacillus

scholarly journals Nano ZnO and its Perspective in Anti-Cancer Activities

2017 ◽  
Vol 16 (2) ◽  
pp. 41-52
Author(s):  
N Shobhaa ◽  
N Nandab ◽  
B M Nagabhushana
Keyword(s):  
Zinc Oxide ◽  
Metal Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Nano Particles ◽  
Oxide Nanoparticles ◽  
Zno Nps ◽  
Large Bandwidth ◽  
Anti Cancer ◽  
Potential Applications

Several methods are used to counter the deadly disease cancer. Zinc oxide nanoparticles (ZnO NPs) is one of the metal oxide nanoparticles which had been used in anti-cancer activities due to its large bandwidth and high exciting binding energy and it has potential applications like antibacterial, antifungal, anti-diabetic, anti-inflammatory, wound healing, antioxidant, optic properties and also which holds promise to treat cancer effectively. Studies have shown that Zinc metal oxide nano particles induce cytotoxicity in cancer cells. The mechanism for antitumor could work through apoptosis or the generation of reactive oxygen species or and necrosis, among other possibilities. This review is on some of the most significant antitumor results obtained with zinc oxide nanoparticles depending on their size, surface morphology, methods of preparation and also cytotoxicity result.

Determination of the bioavailability of zinc oxide nanoparticles using ICP-AES and associated toxicity

2020 ◽  
Vol 188 ◽  
pp. 110767 ◽  
Author(s):  
Sudhakaran S ◽  
Athira SS ◽  
Suresh Babu S ◽  
Varma HK ◽  
Mohanan PV
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles

Evaluation of the catalytic activity of graphene oxide and zinc oxide nanoparticles on the electrochemical sensing of T1R2-Rebaudioside A complex supported by in silico methods

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Krishna Bisetty ◽  
Suvardhan Kanchi ◽  
Phathisanani Hloma
Keyword(s):  
Zinc Oxide ◽  
Graphene Oxide ◽  
Catalytic Activity ◽  
Zinc Oxide Nanoparticles ◽  
Taste Receptor ◽  
Computational Modelling ◽  
Electrochemical Sensing ◽  
Oxide Nanoparticles ◽  
Rebaudioside A ◽  
Pt Electrode

Abstract Herein, we report on the performance of graphene oxide (GOx) and zinc oxide nanoparticles (ZnONPs) on a platinum (Pt) electrode, immobilized with the human T1R2 sweet taste receptor subunit for the detection of rebaudioside A (Reb-A). The characterization studies performed in this work confirmed the thin-layered structure of GOx and the polydispersed nature of ZnONPs. The elucidation of the mass loss observed by TGA demonstrates the stability of GOx. The cyclic voltammetry results for Pt/GOx revealed good catalytic activity over Pt/ZnONPs for adsorption of the T1R2-Reb-A complex. In addition, a series of computational modelling studies were carried out to better understand the surface adsorption phenomena of GOx and ZnONPs to mimic the layer-by-layer electrode modification strategies independently. The strongest interaction energy observed (−573 kcal mol−1) for the direct interaction of ZnONPs onto the Pt electrode surface, demonstrates a stronger adsorption in contrast to the GOx modified Pt electrode (−23 kcal mol−1). However, the overall results for the layered-nanocomposite revealed that the GOx (−256 kcal mol−1) were more strongly adsorbed in contrast to ZnONPs (−231 kcal mol−1) for the detection of the T1R2-ReB-A complex, demonstrating the reliability of our GOx electrode functionalization strategy. The results of this study can potentially be used to improve the design of rapid Reb-A sensors for the food and beverage industry.

Synthesis and Antimicrobial Properties of Zinc Oxide Nanoparticles

2020 ◽  
Vol 20 (10) ◽  
pp. 5977-5996 ◽  
Author(s):  
Saee Gharpure ◽  
Balaprasad Ankamwar
Keyword(s):  
Zinc Oxide ◽  
Zno Nanoparticles ◽  
Zinc Oxide Nanoparticles ◽  
Metal Oxide Nanoparticles ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Physical Contact ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Promising Alternative

With increase in incidence of multidrug resistant pathogens, there is a demand to adapt newer approaches in order to combat these diseases as traditional therapy is insufficient for their treatment. Use of nanotechnology provides a promising alternative as antimicrobial agents as against traditional antibiotics. Metal oxides have been exploited for a long times for their antimicrobial properties. Zinc oxide nanoparticles (ZnO NPs) are preferred over other metal oxide nanoparticles because of their bio-compatible nature and excellent antibacterial potentials. The basic mechanism of bactericidal nature of ZnO nanoparticles includes physical contact between ZnO nanoparticles and the bacterial cell wall, generation of reactive oxygen species (ROS) as well as free radicals and release of Zn2+ ions. This review focuses on different synthesis methods of ZnO nanoparticles, various analytical techniques frequently used for testing antibacterial properties, mechanism explaining antibacterial nature of ZnO nanoparticles as well as different factors affecting the antibacterial properties.

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