scholarly journals PLLA Honeycomb-Like Pattern on Fluorinated Ethylene Propylene as a Substrate for Fibroblast Growth

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2436
Author(s):  
Klára Fajstavrová ◽  
Silvie Rimpelová ◽  
Dominik Fajstavr ◽  
Václav Švorčík ◽  
Petr Slepička
Keyword(s):  
Surface Properties ◽  
Substrate Surface ◽  
Surface Wettability ◽  
Material Surface ◽  
Growth Enhancement ◽  
Fibroblast Growth ◽  
Ethylene Propylene ◽  
Preparation Step ◽  
Cell Material Interactions ◽  
Fluorinated Ethylene Propylene

In this study, we present the surface patterning of a biopolymer poly(l-lactide) (PLLA) for fibroblast growth enhancement. The patterning is based on a self-organized pore arrangement directly fabricated from a ternary system of a solvent-nonsolvent biopolymer. We successfully created a porous honeycomb-like pattern (HCP) on a thermally resistant polymer—fluorinated ethylene propylene (FEP). An important preparation step for HCP is activation of the substrate in Ar plasma discharge. The polymer activation leads to changes in the surface chemistry, which corresponds to an increase in the substrate surface wettability. The aim of this study was to evaluate the influence of the PLLA concentration in solution on the surface morphology, roughness, wettability, and chemistry, and subsequently, also on fibroblast proliferation. We confirmed that the amount of PLLA in solution significantly affects the material surface properties. The pore size of the prepared layers, the surface wettability, and the surface oxygen content increased with an increasing amount of biopolymer in the coating solution. The optimal amount was 1 g of PLLA, which resulted in the highest number of cells after 6 days from seeding; however, all three biopolymer concentrations exhibited significantly better results compared to pristine FEP. The cytocompatibility tests showed that the HCP promoted the attachment of cell filopodia to the underlying substrate and, thus, significantly improved the cell–material interactions. We prepared a honeycomb biodegradable support for enhanced cell growth, so the surface properties of perfluoroethylenepropylene were significantly enhanced.

scholarly journals Special Issue: Biointerface Coatings for Biomaterials and Biomedical Applications

Coatings ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 423
Author(s):  
Hsien-Yeh Chen ◽  
Peng-Yuan Wang
Keyword(s):  
Surface Properties ◽  
Material Science ◽  
Biomedical Applications ◽  
Material Surface ◽  
Special Issue

The success of recent material science and applications in biotechnologies should be credited to developments of malleable surface properties, as well as the adaptation of conjugation reactions to the material surface [...]

scholarly journals Antibacterial Properties of Plasma-Activated Perfluorinated Substrates with Silver Nanoclusters Deposition

Nanomaterials ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 182
Author(s):  
Petr Slepička ◽  
Silvie Rimpelová ◽  
Nikola Slepičková Kasálková ◽  
Dominik Fajstavr ◽  
Petr Sajdl ◽  
...  
Keyword(s):  
Surface Properties ◽  
Antibacterial Properties ◽  
Argon Plasma ◽  
Antimicrobial Effect ◽  
Silver Nanoclusters ◽  
Plasma Modification ◽  
Material Surface ◽  
Silver Deposition ◽  
Force Microscopy ◽  
Atomic Force

This article is focused on the evaluation of surface properties of polytetrafluoroethylene (PTFE) nanotextile and a tetrafluoroethylene-perfluoro(alkoxy vinyl ether) (PFA) film and their surface activation with argon plasma treatment followed with silver nanoclusters deposition. Samples were subjected to plasma modification for a different time exposure, silver deposition for different time periods, or their combination. As an alternative approach, the foils were coated with poly-L-lactic acid (PLLA) and silver. The following methods were used to study the surface properties of the polymers: goniometry, atomic force microscopy, and X-ray photoelectron microscopy. By combining the aforementioned methods for material surface modification, substrates with antibacterial properties eliminating the growth of Gram-positive and Gram-negative bacteria were prepared. Studies of antimicrobial activity showed that PTFE plasma-modified samples coated with PLLA and deposited with a thin layer of Ag had a strong antimicrobial effect, which was also observed for the PFA material against the bacterial strain of S. aureus. Significant antibacterial effect against S. aureus, Proteus sp. and E. coli has been demonstrated on PTFE nanotextile plasma-treated for 240 s, coated with PLLA, and subsequently sputtered with thin Ag layer.

scholarly journals Titanium oral implants: surface characteristics, interface biology and clinical outcome

2010 ◽  
Vol 7 (suppl_5) ◽  
Author(s):  
Anders Palmquist ◽  
Omar M. Omar ◽  
Marco Esposito ◽  
Jukka Lausmaa ◽  
Peter Thomsen
Keyword(s):  
Surface Properties ◽  
Cellular Response ◽  
Randomized Clinical Trials ◽  
Three Dimensional ◽  
Cell Communication ◽  
Surface Characteristics ◽  
Titanium Implants ◽  
Material Surface ◽  
Oral Implants

Bone-anchored titanium implants have revolutionized oral healthcare. Surface properties of oral titanium implants play decisive roles for molecular interactions, cellular response and bone regeneration. Nevertheless, the role of specific surface properties, such as chemical and phase composition and nanoscale features, for the biological in vivo performance remains to be established. Partly, this is due to limited transfer of state-of-the-art preparation techniques to complex three-dimensional geometries, analytical tools and access to minute, intact interfacial layers. As judged by the available results of a few randomized clinical trials, there is no evidence that any particular type of oral implant has superior long-term success. Important insights into the recruitment of mesenchymal stem cells, cell–cell communication at the interface and high-resolution imaging of the interface between the surface oxide and the biological host are prerequisites for the understanding of the mechanisms of osseointegration. Strategies for development of the next generation of material surface modifications for compromised tissue are likely to include time and functionally programmed properties, pharmacological modulation and incorporation of cellular components.

A Multi-Functional Microfluidic Device Compatible with Widefield and Light Sheet Imaging

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Regan P Moore ◽  
Ellen C O’Shaughnessy ◽  
Yu Shi ◽  
Ana T Nogueira ◽  
Katelyn M Heath ◽  
...  
Keyword(s):  
High Resolution ◽  
Microfluidic Device ◽  
Super Resolution ◽  
Light Sheet ◽  
Ethylene Propylene ◽  
Super Resolution Microscopy ◽  
Fluorinated Ethylene Propylene

We present a microfluidic device compatible with high resolution light sheet and super-resolution microscopy. Our device is a 150 μm thick chamber with a transparent fluorinated ethylene propylene (FEP) cover...

Structural optimization of graphite for high-performance fluorinated ethylene–propylene composites as bipolar plates

2018 ◽  
Vol 43 (48) ◽  
pp. 21918-21927 ◽  
Author(s):  
Moon Hee Lee ◽  
Ho Young Kim ◽  
Seong Moon Oh ◽  
Byung Choon Kim ◽  
Daesuk Bang ◽  
...  
Keyword(s):  
Structural Optimization ◽  
High Performance ◽  
Bipolar Plates ◽  
Ethylene Propylene ◽  
Fluorinated Ethylene Propylene
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