scholarly journals Gamma Ray-Induced Polymerization and Cross-Linking for Optimization of PPy/PVP Hydrogel as Biomaterial

Polymers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 111 ◽  
Author(s):  
Jin-Oh Jeong ◽  
Jong-Seok Park ◽  
Young-Ah Kim ◽  
Su-Jin Yang ◽  
Sung-In Jeong ◽  
...  

Conducting polymer (CP)-based hydrogels exhibit the behaviors of bending or contraction/relaxation due to electrical stimulation. They are similar in some ways to biological organs and have advantages regarding manipulation and miniaturization. Thus, these hydrogels have attracted considerable interest for biomedical applications. In this study, we prepared PPy/PVP hydrogel with different concentrations and content through polymerization and cross-linking induced by gamma-ray irradiation at 25 kGy to optimize the mechanical properties of the resulting PPy/PVP hydrogel. Optimization of the PPy/PVP hydrogel was confirmed by characterization using scanning electron microscopy, gel fraction, swelling ratio, and Fourier transform infrared spectroscopy. In addition, we assessed live-cell viability using live/dead assay and CCK-8 assay, and found good cell viability regardless of the concentration and content of Py/pTS. The conductivity of PPy/PVP hydrogel was at least 13 mS/cm. The mechanical properties of PPy/PVP hydrogel are important factors in their application for biomaterials. It was found that 0.15PPy/PVP20 (51.96 ± 6.12 kPa) exhibited better compressive strength than the other samples for use in CP-based hydrogels. Therefore, it was concluded that gamma rays can be used to optimize PPy/PVP hydrogel and that biomedical applications of CP-based hydrogels will be possible.

2009 ◽  
Vol 24 (1) ◽  
pp. 61-67 ◽  
Author(s):  
Milos Vujisic ◽  
Koviljka Stankovic ◽  
Aleksandra Vasic

This paper compares the reliability of standard commercial Erasable Programmable Read Only Memory (EPROM) and Electrically Erasable Programmable Read Only Memory (E2PROM) components exposed to gamma rays. The results obtained for CMOS-based EPROM (NM27C010) and E2PROM (NM93CS46) components provide the evidence that EPROMs have greater radiation hardness than E2PROMs. Moreover, the changes in EPROMs are reversible, and after erasure and reprogramming all EPROM components restore their functionality. On the other hand, changes in E2PROMs are irreversible. The obtained results are analyzed and interpreted on the basis of gamma ray interaction with the CMOS structure.


2018 ◽  
Vol 53 ◽  
pp. 01007
Author(s):  
Yinghong Zuo ◽  
Maoyu Zhang ◽  
Guoxin Cheng ◽  
Shengli Niu

To obtain the transient current response law of the metal component irradiated by pulsed gamma rays, the pulsed gamma ray irradiation experiment of the iron plate was carried out on “Qiangguang-I” accelerator. The transient current of iron plate generated by pulsed gamma rays was measured and analysed, and the relationship between the amplitude of pulse current and the dose rate of gamma rays was obtained. The results show that the current response sensitivity of the iron plate is about 5.7×10-7(A/m2)/(Gy/s) when the gamma rays with the energy of 0.8 MeV irradiate the iron plate. The charge deposition rate in the iron plate can be obtained by Monte Carlo simulation, and then it can be converted to gamma ray induced current of the metal component irradiated by gamma rays.


2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Jong-Seok Park ◽  
Jong-Bae Choi ◽  
Hui-Jeong Gwon ◽  
Youn-Mook Lim ◽  
Myung Seob Khil ◽  
...  

A nanoporous high-density polyethylene (HDPE) membrane was prepared by a wet process. Soybean oil and dibutyl phthalate (DBP) were premixed as codiluents, and gamma-rays were used for the cross-linking of HDPE. The pore volume of the nanoporous HDPE membranes with soybean oil was affected by the extracted amount of oil. The tensile strength of the membrane improved with an increasing absorbed dose up to 60 kGy, but decreased at 80 kGy due to severe degradation. The ionic conductivity of the nanoporous HDPE membrane did not really change with an increasing absorbed dose because the pores had already been formed before the gamma-ray radiation. Finally, the electrochemical stability of the HDPE membrane increased when the absorbed dose increased up to 60 kGy.


2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Eltjani-Eltahir Hago ◽  
Xinsong Li

In this work, a new approach was introduced to prepare interpenetrating polymer network PVA/GE hydrogels by cross-linking of various concentration gelatin in the presence of transglutaminase enzyme by using the freezing-thawing cycles technique. The effects of freezing-thawing cycles on the properties of morphological characterization, gel fraction, swelling, mechanical, and MTT assay were investigated. The IPN PVA/GE hydrogels showed excellent physical and mechanical Properties. MTT assay data and the fibroblasts culture also showed excellent biocompatibility and good proliferation. This indicates that the IPN hydrogels are stable enough for various biomedical applications.


2011 ◽  
Vol 1297 ◽  
Author(s):  
Michael S. Lowry ◽  
Alfredo Rayms-Keller ◽  
Karen J. Long ◽  
Francisco Santiago ◽  
Victor H. Gehman ◽  
...  

ABSTRACTCarbon nanotubes (CNTs) are appealing materials for biomedical applications due to their unique chemical, electrical and mechanical properties. The emphasis of the present work is on controlling the structure and symmetry of carbon nanotubes by imposing an applied stress at the CNT growth site. CNTs were grown under these conditions using standard chemical vapor deposition (CVD) techniques and were subsequently characterized with a scanning electron microscope; the methodology and implications of this approach are discussed herein.


2013 ◽  
Vol 700 ◽  
pp. 136-139
Author(s):  
Xin Tang ◽  
Jin Huang

The mechanical properties and microstructure of cement stone containing different sodium chloride (NaCl) have been investigated. Uni-axial compression experiments were used to study mechanical properties. The main crystalline phase composition of cement specimens was determined by means of X-ray diffraction (XRD). Surface morphology of cement stone was observed by using scanning electron microscopy (SEM). The obtained results showed that compared with the other samples, the sample incorporated 14% sodium chloride was quite different, whose compressive strength was higher and microstructure was denser. The sodium chloride crystalline phase and the hydration (C-S-H) gel phase co-existed.


2008 ◽  
Vol 600-603 ◽  
pp. 707-710
Author(s):  
Shigeomi Hishiki ◽  
Naoya Iwamoto ◽  
Takeshi Ohshima ◽  
Hisayoshi Itoh ◽  
Kazu Kojima ◽  
...  

The effect of the fabrication process of n-channel 6H-SiC MOSFETs on their radiation resistance is investigated. MOSFETs that post implantation annealing for source and drain was carried out with carbon coating on the sample surface are compared to MOSFETs that post implantation annealing was carried out without carbon coating. The radiation resistance (gamma-rays) of the carbon-coated MOSFETs is higher than that of non-coated ones. The channel mobility for MOSFETs whose gate oxide was formed using pyrogenic or dry oxidation process dose not change by gamma-ray irradiation below 1x105 Gy. The value of channel mobility slightly increases with increasing dose above 1x105 Gy. No significant increase in irradiation induced interface traps is observed.


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