scholarly journals The Effect of Diluent Mixture with Upper Critical Solution Temperature on Membrane Formation Process, Microstructure, and Performance of PVDF Hollow Fiber Membrane by TIPS Process

Polymers ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 719 ◽  
Author(s):  
Zhenyu Cui ◽  
Shanshan Xu ◽  
Jinyue Ding ◽  
Jing Zhang ◽  
Benqiao He ◽  
...  
Keyword(s):  
Hollow Fiber ◽  
Formation Process ◽  
Hollow Fiber Membrane ◽  
Solution Temperature ◽  
Fiber Membrane ◽  
Membrane Formation ◽  
Critical Solution Temperature ◽  
Upper Critical Solution Temperature ◽  
And Performance ◽  
Microstructure And Performance

scholarly journals Kinetic Analysis of Lidocaine Elimination by Pig Liver Cells Cultured in 3D Multi-Compartment Hollow Fiber Membrane Network Perfusion Bioreactors

2021 ◽  
Vol 8 (8) ◽  
pp. 104
Author(s):  
Gerardo Catapano ◽  
Juliane K. Unger ◽  
Elisabetta M. Zanetti ◽  
Gionata Fragomeni ◽  
Jörg C. Gerlach
Keyword(s):  
Kinetic Analysis ◽  
Drug Screening ◽  
Hollow Fiber ◽  
Hollow Fiber Membrane ◽  
Liver Cells ◽  
Fiber Membrane ◽  
Bioreactor Design ◽  
Drug Adsorption ◽  
And Performance ◽  
Cells Cultured

Liver cells cultured in 3D bioreactors is an interesting option for temporary extracorporeal liver support in the treatment of acute liver failure and for animal models for preclinical drug screening. Bioreactor capacity to eliminate drugs is generally used for assessing cell metabolic competence in different bioreactors or to scale-up bioreactor design and performance for clinical or preclinical applications. However, drug adsorption and physical transport often disguise the intrinsic drug biotransformation kinetics and cell metabolic state. In this study, we characterized the intrinsic kinetics of lidocaine elimination and adsorption by porcine liver cells cultured in 3D four-compartment hollow fiber membrane network perfusion bioreactors. Models of lidocaine transport and biotransformation were used to extract intrinsic kinetic information from response to lidocaine bolus of bioreactor versus adhesion cultures. Different from 2D adhesion cultures, cells in the bioreactors are organized in liver-like aggregates. Adsorption on bioreactor constituents significantly affected lidocaine elimination and was effectively accounted for in kinetic analysis. Lidocaine elimination and cellular monoethylglicinexylidide biotransformation featured first-order kinetics with near-to-in vivo cell-specific capacity that was retained for times suitable for clinical assist and drug screening. Different from 2D cultures, cells in the 3D bioreactors challenged with lidocaine were exposed to close-to-physiological lidocaine and monoethylglicinexylidide concentration profiles. Kinetic analysis suggests bioreactor technology feasibility for preclinical drug screening and patient assist and that drug adsorption should be accounted for to assess cell state in different cultures and when laboratory bioreactor design and performance is scaled-up to clinical use or toxicological drug screening.

Fabrication of zirconia-kaolin dual layer hollow fiber membrane: Physical and performance study for industrial wastewater treatment

2021 ◽  
Vol 41 ◽  
pp. 102031
Author(s):  
Mohammad Arif Budiman Pauzan ◽  
Mohd Hafiz Dzarfan Othman ◽  
Nurul Jannah Ismail ◽  
Mohd Hafiz Puteh ◽  
Ahmad Fauzi Ismail ◽  
...  
Keyword(s):  
Wastewater Treatment ◽  
Hollow Fiber ◽  
Industrial Wastewater ◽  
Hollow Fiber Membrane ◽  
Fiber Membrane ◽  
Performance Study ◽  
Industrial Wastewater Treatment ◽  
And Performance

Structure Morphology of Polyethersulfone Hollow Fiber Membrane via Immersion Precipitation Phase Inversion Process

2012 ◽  
Vol 152-154 ◽  
pp. 574-578 ◽  
Author(s):  
Ping Lan ◽  
Wei Wang
Keyword(s):  
Hollow Fiber ◽  
Phase Inversion ◽  
Hollow Fiber Membrane ◽  
Pure Water ◽  
Water Flux ◽  
Additive Concentration ◽  
Hollow Fiber Membranes ◽  
Fiber Membrane ◽  
Fiber Membranes ◽  
And Performance

Polyethersulfone (PES) hollow fiber membranes have been widely used in many fields, such as ultrafiltration, microfiltration, reverse osmosis, liquid/liquid or liquid/solid separation, gas separation, hemodialysis, and so on. In this paper, the sheet PES hollow fiber membranes were prepared. The morphology and performance of membranes can be controlled. By studying the influence of the compositions and conditions on the morphology and performance of PES hollow fiber membrane, the relationship of morphology and performance of the membrane is acquired. The additives were used such as glycerol, BuOH and PEG. In addition, immerse phase inversion was used as membranes preparation method. The morphology of the membrane was controlled by changing kinds of additive, concentration of additive and so on. It was found that the membrane morphologies were changed by additive obviously. Porosity , pure water flux, scanning electron microscopy(SEM) were used to characterize the morphology and performance of the membranes.

The effect of annealing and stretching parameters on the structure and performance of polypropylene hollow fiber membrane

2019 ◽  
Vol 6 (5) ◽  
pp. 054001
Author(s):  
A A I A S Komaladewi ◽  
S Anisah ◽  
A K Wardani ◽  
I W Surata ◽  
I D G A Subagia ◽  
...  
Keyword(s):  
Hollow Fiber ◽  
Hollow Fiber Membrane ◽  
Fiber Membrane ◽  
And Performance

Morphology and performance of polysulfone hollow fiber membrane

1993 ◽  
Vol 49 (3) ◽  
pp. 539-548 ◽  
Author(s):  
Soon Hong Lee ◽  
Jae-Jin Kim ◽  
Sung Soo Kim ◽  
Un Young Kim
Keyword(s):  
Hollow Fiber ◽  
Hollow Fiber Membrane ◽  
Fiber Membrane ◽  
And Performance

Effect of diluent on poly(ethylene-co-vinyl alcohol) hollow-fiber membrane formation via thermally induced phase separation

2004 ◽  
Vol 95 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Mengxian Shang ◽  
Hideto Matsuyama ◽  
Masaaki Teramoto ◽  
Junpei Okuno ◽  
Douglas R. Lloyd ◽  
...  
Keyword(s):  
Phase Separation ◽  
Hollow Fiber ◽  
Vinyl Alcohol ◽  
Hollow Fiber Membrane ◽  
Thermally Induced Phase Separation ◽  
Fiber Membrane ◽  
Membrane Formation ◽  
Thermally Induced ◽  
Poly Ethylene
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