scholarly journals Response of Arabidopsis thaliana Roots with Altered Lipid Transfer Protein (LTP) Gene Expression to the Clubroot Disease and Salt Stress

Plants ◽  
2015 ◽  
Vol 5 (1) ◽  
pp. 2 ◽  
Author(s):  
Sabine Jülke ◽  
Jutta Ludwig-Müller
Keyword(s):  
Gene Expression ◽  
Arabidopsis Thaliana ◽  
Salt Stress ◽  
Lipid Transfer Protein ◽  
Lipid Transfer ◽  
Clubroot Disease ◽  
Transfer Protein ◽  
Altered Lipid

scholarly journals Pattern Formation in the Arabidopsis Embryo Revealed by Position-Specific Lipid Transfer Protein Gene Expression

1996 ◽  
Vol 8 (5) ◽  
pp. 783 ◽  
Author(s):  
Casper W. Vroemen ◽  
Sandra Langeveld ◽  
Ulrike Mayer ◽  
Gabriela Ripper ◽  
Gerd Jurgens ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pattern Formation ◽  
Protein Gene ◽  
Lipid Transfer Protein ◽  
Lipid Transfer ◽  
Transfer Protein ◽  
Specific Lipid

scholarly journals ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

2021 ◽  
Author(s):  
William F Hancock-Cerutti ◽  
Zheng Wu ◽  
Arun Kumar Tharkeshwar ◽  
Shawn M Ferguson ◽  
Gerald S Shadel ◽  
...  
Keyword(s):  
Autosomal Recessive ◽  
Lipid Transfer Protein ◽  
Lipid Transfer ◽  
Parkinsons Disease ◽  
Transfer Protein ◽  
G2019s Mutation ◽  
Late Endosomes ◽  
Lrrk2 G2019s ◽  
Sting Pathway ◽  
Altered Lipid

Mutations in VPS13C cause early onset, autosomal recessive Parkinsons Disease (PD). We have established that VPS13C encodes a lipid transfer protein localized to contact sites between the endoplasmic reticulum (ER) and late endosomes/lysosomes. In the current study, we demonstrate that depleting VPS13C in HeLa cells causes an accumulation of lysosomes with an altered lipid profile, including an accumulation of di-22:6 BMP, a biomarker of the PD-associated leucine-rich repeat kinase 2 (LRRK2) G2019S mutation. In addition, the DNA-sensing cGAS/STING pathway, which was recently implicated in PD pathogenesis, is activated in these cells. This activation results from a combination of elevated mitochondrial DNA in the cytosol and a defect in the degradation of activated STING, a lysosome-dependent process. These results suggest a link between ER-lysosome lipid transfer and innate immune activation and place VPS13C in pathways relevant to PD pathogenesis.

A wheat lipid transfer protein (TdLTP4) promotes tolerance to abiotic and biotic stress in Arabidopsis thaliana

2015 ◽  
Vol 89 ◽  
pp. 64-75 ◽  
Author(s):  
Hela Safi ◽  
Walid Saibi ◽  
Meryem Mrani Alaoui ◽  
Abdelaziz Hmyene ◽  
Khaled Masmoudi ◽  
...  
Keyword(s):  
Arabidopsis Thaliana ◽  
Biotic Stress ◽  
Lipid Transfer Protein ◽  
Lipid Transfer ◽  
Abiotic And Biotic Stress ◽  
Transfer Protein

scholarly journals Pattern Formation in the Arabidopsis Embryo Revealed by Position-Specific Lipid Transfer Protein Gene Expression.

1996 ◽  
pp. 783-791 ◽  
Author(s):  
C. W. Vroemen ◽  
S. Langeveld ◽  
U. Mayer ◽  
G. Ripper ◽  
G. Jurgens ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pattern Formation ◽  
Protein Gene ◽  
Lipid Transfer Protein ◽  
Lipid Transfer ◽  
Transfer Protein ◽  
Specific Lipid
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