scholarly journals Study of Bio-Pharmaceutical and Antimicrobial Properties of Pomegranate (Punica granatum L.) Leathery Exocarp Extract

Plants ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 153
Author(s):  
Hazem S. Elshafie ◽  
Lucia Caputo ◽  
Laura De Martino ◽  
Shimaa H. Sakr ◽  
Vincenzo De Feo ◽  
...  
Keyword(s):  
Xanthomonas Campestris ◽  
Phytophthora Cinnamomi ◽  
Solid Phase ◽  
Antioxidant Activities ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Punica Granatum ◽  
Inhibitory Effect ◽  
Phytopathogenic Fungi ◽  
Punica Granatum L

Pomegranate (Punica granatum L.) fruits are important sources of vitamins and minerals and widely used in the dietary supplement industry. An aqueous extract of its leathery exocarp (LEP) was obtained by a solid-phase micro-extraction method. The antifungal activity was examined against the phytopathogenic fungi, Fusarium oxysporum, Phytophthora cinnamomi, Penicillium digitatum and Botrytis cinerea, and the antibacterial activity was evaluated against Escherichia coli, Xanthomonas campestris,Bacillus megaterium and Clavibacter michiganensis. The antimicrobial assays showed, in some cases, a promising antimicrobial effect compared to the synthetic drugs. The possible anti-acetylcholinesterase and antioxidant activities of the LEP extract were investigated by the Ellman’s assay and 2,2-diphenyl-1-picrylhydrazyl (DPPH) test, respectively, and their results showed that the LEP extract has an effective anti-acetylcholinesterase inhibitory effect and an antioxidant activity. Thus, the LEP extract could be valid as a candidate for further studies on the use of pomegranate in neurodegenerative diseases as a food preservative and a suitable substitute to control several phytopathogens.

scholarly journals Comparison of five solvents in the extraction of phenolic anti-oxidants from pomegranate (Punica granatum L.) peel

2019 ◽  
Vol 3 (5) ◽  
pp. 140-147
Author(s):  
Abderrezak Kennas ◽  
Hayat Amellal-Chibane
Keyword(s):  
Antioxidant Activity ◽  
Phenolic Content ◽  
Antioxidant Activities ◽  
Punica Granatum ◽  
Extraction Yield ◽  
Total Phenolic ◽  
Phenolic Antioxidants ◽  
Punica Granatum L ◽  
Extracting Solvent ◽  
High Inhibition

Background: Pomegranate peels are rich in bioactive compounds and could be an alternative natural source such as antioxidants. Aims: The aim of the present study was to assess the abilities of five solvents to extract phenolic antioxidants from pomegranate peels. Methods and Material: Pomegranate peels powder was subjected to extraction and the extraction yield was compared. The total phenolic, flavonoid, condensed and hydrolysable tannins contents were analyzed. The antioxidant activity of the extracts was evaluated by two methods (DPPH* and ABTS•+ scavenging capacities) and results were then compared. Results: Results showed that the mixture methanol/water (50:50) allowed higher extraction yield (37.33±5.3%) than the others solvents (P<0.05). Further, the total phenolic, flavonoid and condensed tannins contents were the highest in mixture water/methanol (50:50) extract. Phenolic antioxidants showed a distinct reducing capacity and a high DPPH* inhibition values were recorded for all extracts with no significant differences (P>0.05) between ethanol and mixture water/methanol (50:50) extracts. All extracts exhibited high inhibition against ABTS•+ but with a considerable variation. Phenolic content and antioxidant activities were well positively correlated with each other. Conclusions: Our findings revealed that the choice of the extracting solvent affects considerably the extraction of phenolic antioxidants from pomegranate peels. Keywords: Pomegranate peels, solvent extraction, antioxidant activity, phenolic antioxidants.

Punica granatum L. (Pomegranate): A Potential Anti-microbial Agent

2020 ◽  
Vol 18 (1) ◽  
pp. 2-14 ◽  
Author(s):  
Aida Doostkam ◽  
Kamyar Iravani ◽  
Shahindokht Bassiri-Jahromi
Keyword(s):  
Antimicrobial Properties ◽  
Punica Granatum ◽  
Future Application ◽  
Potential Health ◽  
Therapeutic Uses ◽  
Animal Trial ◽  
Microbial Infections ◽  
Punica Granatum L

: Polyphenols have received high attention due to their biological functions. Pomegranate (Punica granatum L.) is a rich source of polyphenols such as tannin, ellagitannin, flavonoids and other phenolic acids. The potential therapeutic uses of pomegranate appear to be wide diversity. Pomegranate contains strong antioxidant activity, and antimicrobial properties, with potential health interests. : This review has been performed on a method of systematic narrative review on the antimicrobial potency of different parts of pomegranate. A search was performed in PubMed, Web of Science, Science Direct, Scopus and Google Scholar from 1986 to 2018 to obtain related studies. The aim of this review present an overview of the aspect and advantages of Punica granatum L. and summarize the present data on the pomegranate anti-microbial activity in in-vitro and in-vivo tests, animal trial systems and human clinical trials. Also, this review discussed the pomegranate extracts activities and their future application. : The findings of this review support that the pomegranate might be possible to use in the control and potential therapeutics of some microbial infections. This review highlights the new researches on the anti-microbial activities of pomegranate.

scholarly journals Phenolic profiles and antioxidant activities of six Chinese pomegranate (Punica granatum L.) cultivars

2017 ◽  
Vol 20 (sup1) ◽  
pp. S94-S107 ◽  
Author(s):  
Linlin Yan ◽  
Xiaojing Zhou ◽  
Lingling Shi ◽  
Dilinuer Shalimu ◽  
Chao Ma ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Punica Granatum ◽  
Phenolic Profiles ◽  
Punica Granatum L

scholarly journals Phytochemical Characteristics and Pharmacological Properties Studies of the Powders of Punica granatum L. (Lythraceae) Leaves from Seven Regions of Burkina Faso with a View to Standardizing

2021 ◽  
pp. 1-11
Author(s):  
Salfo Ouédraogo ◽  
Tata Kadiatou Traoré ◽  
Benjamin Ouedraogo ◽  
Boladé Constantin Atchadé ◽  
Adjaratou Coulibaly ◽  
...  
Keyword(s):  
Burkina Faso ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Punica Granatum ◽  
Total Phenolic ◽  
Pharmacological Properties ◽  
Phytochemical Screening ◽  
Ethanolic Extracts ◽  
Layer Chromatography ◽  
Punica Granatum L

Introduction: Punica granatum is a plant used in traditional and alternative medicine for the management of several diseases. Objective: The objective of the present work is to compare the phytochemical characteristics and the antioxidant properties of extracts of leaves powders of Punica granatum L. collected for standardization. Methodology: We worked on seven samples of powders of leaves of Punica granatum L collected in seven different regions of Burkina Faso. Two types of extracts, aqueous and hydroethanolic were prepared with each sample. We performed a phytochemical screening by thin layer chromatography (TLC), then determined the content of the various extracts in total phenolic and flavonoids as well as a study of the antioxidant activity of the aqueous and hydro-ethanolic extracts of the plant. Results: Fourteen extracts of Punica granatum are obtained and these contain secondary metabolites such as tannins, sterols, triterpenes, saponosides and flavonoids. The anti-free radical activities at the DPPH* were more important in the samples from the towns of Dedougou, Banfora and Fada. The anti-free radicals at ABTS of extracts from the towns of Manga, Banfora, Fada and Kaya were found to be the most active. The FRAP test shows better activity of samples from the cities, Manga, Dedougou and Banfora. Conclusion: At the end of this work, the towns of Dedougou and Banfora may be the sites to be favored as harvesting sites because their samples were the richest in phenolic compounds and had the best antioxidant activities compared to the tests carried out.

scholarly journals Antimicrobial properties of phytohormone (gibberellins) against phytopathogens and clinical pathogens

2021 ◽  
Vol 3 (10) ◽  
Author(s):  
Paoirse Toner ◽  
David Nelson ◽  
Juluri R. Rao ◽  
Madeleine Ennis ◽  
John E. Moore ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Antimicrobial Properties ◽  
Inhibitory Effect ◽  
Phytopathogenic Fungi ◽  
Microbial Pathogens ◽  
Inhibitory Effects ◽  
Plant Host ◽  
Therapeutic Value ◽  
Wide Range

The in vitro antimicrobial potential of physiologically active diterpenoid plant-derived gibberellins (gibberellic acids; GAs) was tested on microbial pathogens of significance to plant and human health. The racemic enantiomer GA3 produced varying inhibitory effects against a wide range of plant host disease causal agents (phytopathogens) comprising fungi, oomycetes and bacteria. The results showed that GA3 effected either strong growth arrest of phytopathogenic fungi or holistic biocidal effects on oomycete and phytopathogenic fungi at higher concentration (>10–50 mM) and increased hyphal extension growth when the concentration of GA3 was lowered (<10−0.1 mM). When human clinical pathogenic bacteria cohorts were challenged with gibberellin enantiomers, viz GA1, GA4, GA5, GA7, GA9 and GA13 (50 mM), employing Kirby–Bauer disc bioassay methods for assessment of their efficacies, no inhibitory effect was seen with gibberellin enantiomers, viz GA1, GA3, GA5 and GA13, while GA4 inhibited all human clinical bacterial organisms examined, with GA7 and GA9 showing limited activity. The antibiotic effects of enantiomeric diterpenoid phytohormones evinced in our preliminary study raise prospects for further studies to fully examine their potential therapeutic value for human healthcare and their compliance with cytotoxicity and other ethical considerations in the future.

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