scholarly journals Antifungal Activity of 14-Helical β-Peptides against Planktonic Cells and Biofilms of Candida Species

2015 ◽  
Vol 8 (3) ◽  
pp. 483-503 ◽  
Author(s):  
Namrata Raman ◽  
Myung-Ryul Lee ◽  
David Lynn ◽  
Sean Palecek
2012 ◽  
Vol 61 (12) ◽  
pp. 1704-1708 ◽  
Author(s):  
Rosana Serpa ◽  
Emanuele J. G. França ◽  
Luciana Furlaneto-Maia ◽  
Célia G. T. J. Andrade ◽  
Andréa Diniz ◽  
...  

Gene Reports ◽  
2021 ◽  
Vol 25 ◽  
pp. 101369
Author(s):  
Maryam Bakhshi ◽  
Samira Salari ◽  
Pooya Ghasemi Nejad Almani ◽  
Setareh Agha Kuchak Afshari

2020 ◽  
Vol 143 ◽  
pp. 341-348 ◽  
Author(s):  
Lana Glerieide Silva Garcia ◽  
Glaucia Morgana de Melo Guedes ◽  
Xhaulla Maria Quariguasi Cunha Fonseca ◽  
Waldemiro Aquino Pereira-Neto ◽  
Débora Souza Collares Maia Castelo-Branco ◽  
...  

2015 ◽  
Vol 15 (4) ◽  
Author(s):  
Rossana de A. Cordeiro ◽  
Carlos E.C. Teixeira ◽  
Raimunda S.N. Brilhante ◽  
Débora S.C.M. Castelo-Branco ◽  
Lucas P. Alencar ◽  
...  

2014 ◽  
Vol 9 (7) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Nuño Gabriela ◽  
Alberto María Rosa ◽  
Zampini Iris Catiana ◽  
Cuello Soledad ◽  
Ordoñez Roxana Mabel ◽  
...  

Zuccagnia punctata Cav. has been used as a traditional medicine in Argentina for the treatment of bacterial and fungal infections. In this study, we evaluated the ability of Z. punctata extract (ZpE) and compounds isolated from it to inhibit the growth and virulence factors of Candida species. ZpE showed inhibitory activity against planktonic cells of all assayed Candida species with MIC values of 400 μg/mL and with MFC values between 400 and 1,200 μg/mL. The principal identified compounds by HPLC-MS/MS and UV-VIS were chalcones (2′,4′-dihydroxy-3′-methoxychalcone, 2′,4′- dihydroxychalcone), flavones (galangin, 3,7-dihydroxyflavone and chrysin) and flavanones (naringenin, 7-hydroxyflavanone and pinocembrine). These compounds were more effective as inhibitors than the extracts upon biofilm formation as well as on preformed Candida biofilm and yeast germ tube formation. Furthermore, ZpE and chalcones are able to inhibit exoenzymes, which are responsible for the invasion mechanisms of the pathogens. All these effects could moderate colonization, thereby suppressing the pathogen invasive potential. Our results indicate that ZpE and chalcones could be used in antifungal therapy.


2013 ◽  
Vol 175 (3-4) ◽  
pp. 273-279 ◽  
Author(s):  
Jinqing Zhang ◽  
Wei Liu ◽  
Jingwen Tan ◽  
Yi Sun ◽  
Zhe Wan ◽  
...  

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