scholarly journals Logic Gates Based on DNA Aptamers

2020 ◽  
Vol 13 (11) ◽  
pp. 417
Author(s):  
Mariia Andrianova ◽  
Alexander Kuznetsov

DNA bio-computing is an emerging trend in modern science that is based on interactions among biomolecules. Special types of DNAs are aptamers that are capable of selectively forming complexes with target compounds. This review is devoted to a discussion of logic gates based on aptamers for the purposes of medicine and analytical chemistry. The review considers different approaches to the creation of logic gates and identifies the general algorithms of their creation, as well as describes the methods of obtaining an output signal which can be divided into optical and electrochemical. Aptameric logic gates based on DNA origami and DNA nanorobots are also shown. The information presented in this article can be useful when creating new logic gates using existing aptamers and aptamers that will be selected in the future.

2018 ◽  
Vol 7 (2) ◽  
pp. 178
Author(s):  
Satri Yadi ◽  
Yuniarti Munaf ◽  
Dhasono Dhasono

AbstrakAso Gumbalo dalam penciptaan karya seni lukis diilhami dari kehidupan pengembala yang menjadi inspirasi pencipta yang diungkap melalui media seni lukis dengan mengambil ide “Harapan Pengembala” (Aso Gumbalo). Harapan Gembala dapat diartikan sebagai keinginan, kecendrungan dan dorongan hati yang kuat terhadap sesuatu hal yang ingin direalisasikan untuk menjadikan seorang lebih baik dimasa depan. Pengekspresian ide cipta berangkat dari fenomena Aso Gumbalo yang pencipta ungkap dengan ekspresi simbolik kedalam penciptaan karya seni lukis. Metode penciptaan karya ini melalui tahapan yaitu; 1) Tahap eksplorasi adalah tahap pencarian ide-ide dengan melakukan riset emik dan etik untuk pembuatan karya, 2) Tahap perancangan yaitu tahap pembuatan purwarupa yang akan diwujudkan kedalam bentuk karya seni lukis, 3) Tahap proses garapan karya. Konsep dari penciptaan karya merupakan ekspresi simbolik dengan memanfaatkan idiom tradisi, ekspresi tersebut digambarkan pada perwujudan karya menggunakan strategi media dan strategi visual dengan menggunakan konsep pengolahan bentuk, yaitu disformasi dan transformasi dengan melakukan penggabungan beberapa teknik antara lain, teknik plakat, transparan, tekstur semu dan tekstur nyata. Aso Gumbalo sebagai inspirasi yang diungkapkan dalam bentuk karya seni lukis ekspresi simbolik. Karya-karya yang diciptakan pengkarya disajikan dalam bentukpameran.           Kata Kunci:aso gumbalo, ekspresi simbolik, seni lukis.   AbstractAsoGumbalo in the creation of painting works was inspired from the life of the shepherd who became the inspiration of the creator which revealed through the medium of painting by taking the idea of "Hope of the Shepherd" (AsoGumbalo). Shepherd Hope can be interpreted as a strong desire, inclination and encouragement towards something that wants to be realized to make someone better in the future. The expression of copyrighted ideas departs from the phenomenon of AsoGumbalo, which the creator expressed with a symbolic expression into the creation of painting. This method of creating works through several stages, namely; 1) The exploration phase is the stage of searching for ideas by conducting emic and ethical research for the production of works, 2) the design phase that is the prototype-making stage which will be realized in the form of painting, 3) the process stage of the work done. The concept of creation of works is a symbolic expression by utilizing traditional idioms, these expressions are depicted in the realization of the work using media strategies and visual strategies by using the concept of form processing, namely deformation and transformation by combining several techniques, such as plaque, transparent, pseudo-texture and real texture. AsoGumbalo as an inspiration expressed in the form of paintings of symbolic expression. works created by artists are presented in the form of exhibitions.  Keywords:asogumbalo, symbolic expression, painting.  


2019 ◽  
Vol 24 (2) ◽  
pp. 343-367
Author(s):  
Roberto Paura

Transhumanism is one of the main “ideologies of the future” that has emerged in recent decades. Its program for the enhancement of the human species during this century pursues the ultimate goal of immortality, through the creation of human brain emulations. Therefore, transhumanism offers its fol- lowers an explicit eschatology, a vision of the ultimate future of our civilization that in some cases coincides with the ultimate future of the universe, as in Frank Tipler’s Omega Point theory. The essay aims to analyze the points of comparison and opposition between transhumanist and Christian eschatologies, in particular considering the “incarnationist” view of Parousia. After an introduction concern- ing the problems posed by new scientific and cosmological theories to traditional Christian eschatology, causing the debate between “incarnationists” and “escha- tologists,” the article analyzes the transhumanist idea of mind-uploading through the possibility of making emulations of the human brain and perfect simulations of the reality we live in. In the last section the problems raised by these theories are analyzed from the point of Christian theology, in particular the proposal of a transhuman species through the emulation of the body and mind of human beings. The possibility of a transhumanist eschatology in line with the incarnationist view of Parousia is refused.


2021 ◽  
Vol 13 (2) ◽  
Author(s):  
Lyudmila Ivancheva ◽  

The article emphasizes the role of the advancement of modern science and new technologies in forecasting research as a key factor for making prognoses for the future. It presents the concept of technoscience, developed by the author, as a blend and symbiosis of modern science and technologies, converging on the basis of similar purposes, objects of treatment and outcomes, as well as of the rising engagement with social interests and attitudes. Furthermore, the main kinds of forecasting research with their specifics, advantages and limitations are outlined, pointing out the special role of building foresight scenarios for the future as a prognosis and policy instrument. The tendencies in this field of research are identified, revealing the challenges related to modern technoscience, and the possible solutions.


Author(s):  
Małgorzata Mączko

The article aims to analyse the phenomenon of a Norwegian Internet-TV show for teenage audiences, Skam (2015–2017). The transmedia storytelling used in this production resulted in unforeseen international acclaim, subsequently leading to the creation of local remakes of the series. The article will outline the main issues that the show has dealt with, as well as the immersion-building narrative solutions used by the creators. Moreover, it will discuss Skam’s reception by Norwegian and international audiences, and suggest potential directions for the future development of this format.


Author(s):  
Novi Noviar nurdin kasim ◽  
Imelda Meldawati Artayani

Kampung Kara’ba merupakan kampung nelayan yang ada di pesisir Kota Makassar  yang  pada kenyataannya kurang tertata dan diperhatikan. Disamping legalitas bermukim yang tidak ada, Kampung Kara'ba masuk dalam kategori rawan akan bencana alam seperti ombak pasang,  banjir, angin  puyuh dan juga  ancaman akan penggusuran yang terus meresahkan kalangan masyarakat Kara'ba, bahkan sampai pada pembangunan disekitarnya yang memaksa masyarakat nelayan Kara'ba mau tidak mau harus beralih profesi. Hal itu juga yang menyebabkan adanya wacana penataan dan perencanaan Kampung Kara'ba. Maka dari itu perlu adanya penggalian data eksisting dan aktivitas pada Kampung Nelayan Kara’ba agar nantinya bisa menjadi masukan rencana desain. Dengan menggunakan metode partisipatif atau pelibatan warga dan pihak-pihak terkait secara menyeluruh serta observasi lapangan, penulisan ini bertujuan untuk mengetahui kondisi eksisting dan aktivitas Kampung Nelayan Kara’ba. Pada pesisir pantai Makassar, terdapat berbagai macam kondisi  eksisting dan aktivitas yang dilakukan  oleh penduduk setempat maupun pengunjung. Berdasarkan analisis yang dilakukan, didapatkan hasil bahwa ada beberapa kondisi eksisting yang memungkinkan untuk dimasukkan dalam rencana perancangan Kampung Nelayan Kara’ba, tetapi ada pula yang sebaiknya dihilangkan demi terciptanya suatu rancangan bersama, yang diharapkan dapat menyelesaikan permasalahan ditingkatan warga dan tidak lagi menimbulkan permasalahan kedepannya, sehingga dari proses tersebut terciptalah hasil desain perancangan permukiman Kara'ba yang bercirikan perkampungan suku Bugis-Makassar dengan infrastruktur, fasilitas umum, sosial, dan ekonomi yang memadai,  serta penekanan hunian yang merupakan transformasi pembaharuan rumah tradisional Bugis-Makassar dengan sentuhan arsitektur neo-vernakuler. Kata kunci: permukiman nelayan, kondisi eksisting, aktivitas, partisipatif, profesi, perancangan.   Kara'ba Kampoong   is a fisherman's kampoong in cost city of Makassar which in fact unattended and   less organized. Beside of that, there is no legality settled. Kara'ba Kampoong included in the prone to natural disasters category such as tidal wave, flood, whirlwind, and also threats of evictions that make people restless, and even to the surrounding development forced the fishing community in Kara'ba to change their job.  It also  causes the arrangement discourse and planning of Kara'ba Kampoong. So, it is very important the existence of extracting fisherman kampoong, so that later can be include by design plan. By using the participative method or involving   the community and related parties overall and field observation. This writing aims to know  about  existing  condition and activities in Kara'ba Fisherman Kampoong. In cost city of Makassar, there are many kind of existing conditions which allows to be included in designing planing of Kara'ba Fisherman Kampoong, but some of them should not exist for the creation of a joint design, which is expected to solve the problems in the future, so by that process designing of Kara'ba settlement can be created which is the character of the Fisherman Kampong Bugis- Makassar with infrastruckture, public facilities, sosial, adequate economy, and four types of dwellings are tranformation of traditional house renewal Bugis-Makassar with architecture neo-vernakuler.


Author(s):  
Margarita G. Bogatkina ◽  
Elena S. Doroschuk ◽  
Tatiana S. Staroverova

Today the convergence processes determine the most promising areas of modern science. This methodological setting in the field of journalism is implemented in a variety of multimedia forms, which has led to the creation of the fundamentally new information and communication environment and the emergence of a variety of multimedia projects. The question about the criteria and methods for creating a high-quality multimedia product remains open. The multimedia method of perception and presentation of materials require special philological preparation and mastering of the interdisciplinary technique of interpretation of the source materials, which would help to create its qualitative multimedia variation. To transfer the literary discourse into a multimedia projection, it is necessary to identify its semantic channels, contexts that can be implemented in the cross-media content using various technical means. In this regard, it is important to substantiate the basic principles of the contextual method of interpreting literary discourse. It is also proposed to highlight contexts that are present in the discourse and are actualized by the perceiving recipient including historical, biographical, literary, linguistic, philosophical, mythological, literary critical, as well as those of various types of art - painting, music, etc., and the scientific context. The structure-forming principle that allows comprehending these contexts as an integral system is the process of dialogic interaction of their intra- and extra-textual existence. The nature of the functioning of this context system is based on the implementation of the following factors: 1) the degree to which authorial/reader determinism manifests itself in the process of implementation of a specific context; 2) the degree of awareness/unconsciousness of the context embodiment in the work; 3) the degree of relative stiffness/probability of the context functioning; and 4) the degree of certainty/uncertainty of the implementation of the external context in the literary discourse. Considering an example of the story by Sholokhov, “The Fate of Man”, it is considered as the development of the context system in the form of a substantive basis for the further transfer of this text into a multimedia projection. It is revealed that the literary discourse is born at the junction of information and communication approaches to the text. The disclosure of the multimedia nature of literary discourse helps to restore the very process of its functioning and its dialogical nature. The contextual methodology for the interpretation of literary discourse also allows determining the dialogue channels - the context system that are the basis for the creation of high-quality multimedia content in the future. Since the multimedia method of material perception and presentation requires special preparation, it is advisable to develop the skills of multimedia thinking using the example of classical literature, based on the principles of contextual methodology. A philological literacy can also play an important role in the process of training future journalists.


2020 ◽  
Vol 15 (4) ◽  
Author(s):  
Milan Tomašević

The paper offers a definition of cosmology and its connections with mythology, and presents contemporary theories as a secular mythical narrative suitable for anthropological analysis. The paper is dedicated to emphasizing the folklore characteristics of modern cosmology and points to the importance of popular cosmological narratives as reading that contains culturally, philosophically and even religiously relevant elements. Special attention is paid to cosmogonic myths that describe the state of the universe before the creation of space and time. A parallel has been drawn between modern cosmology and conventional cosmogonic myths. In the end, the paper offers a concise definition of popular cosmology and recalls the most important authors and popularizers of modern theories. The main task of the paper is to present the basic concepts that can contribute to a complete understanding of the anthropological character of the presentation of contemporary cosmology that we encounter in popular narratives. The aim of such an analysis is to observe the depth of the significance of modern science for creating a philosophical picture of the world that inherits secular worldviews. By treating popular cosmology as a modern myth, the paper presents a new dimension of the significance of scientific theories for today's civilization. Such an approach unravels the strictly positivist halo of cosmology and points to its anthropological character. The concepts highlighted in the paper serve as an illustration of the significance that the image of the universe and the position of the Earth has for the history of civilization. By presenting the cultural dimension of cosmology, it opens a space for dialogue between different branches of scientific research, i.e. it contributes to the communication of philosophy and science. Equally important, by illuminating the folklore character of the narrative of the origin and history of the universe, a training ground is created for philosophers and theologians who, in their own ways, interpret the creation of everything around us. By drawing attention to authors such as Neil deGrasse Tyson, Lawrence Kraus, Stephen Hawking, Michio Kaku and others, as contemporary bards and narrators, the paper seeks to contribute to the understanding of popular cosmology as an expression of modern man's need for great stories, for narratives that transcend the spatial and temporal frames of one generation, and that is exactly what myths do.


Author(s):  
Jonathan Baron

This chapter discusses three impediments to proper use of science in the creation of public policy. First, citizens and policymakers follow moral rules other than those that involve consequences, yet the main role of science in policy is to predict outcomes. Second, citizens believe that their proper role is to advance their self-interest or the interest of some narrow group, thus ignoring the relevance of science to policy issues that affect humanity now and in the future. Third, people fail to understand the nature of science as grounded in actively open-minded thinking, thus giving it an advantage over some alternative ways of forming beliefs.


The Analyst ◽  
2021 ◽  
Author(s):  
Pumidech Puthongkham ◽  
Supacha Wirojsaengthong ◽  
Akkapol Suea-Ngam

This minireview introduces the principles and recent applications of machine learning and experimental designs in developing and improving electrochemical sensors.


Futures ◽  
2021 ◽  
pp. 500-513
Author(s):  
Christina Garsten ◽  
Adrienne Sörbom

This chapter critiques the anticipatory practices of contemporary organizations, such as think tanks and management consultancies, which offer methods and forecasts about possible and desirable futures. These organizations, the chapter argues, contribute to creating a sense of urgency with respect to the future, capitalizing on the perceived need among decision makers to grasp contemporary events, and provide tools and content by which the future can be designed. It argues that future forecast scenarios assist in the creation of a particular type of authority: one geared to the contemporary global situation and to an increasingly complex system of global governance. The chapter interrogates this particular type of authority to argue it is not singular and dominant, but instead comprises the varying interests of many different actors and is underscored by rational process, which offers the possibility of a wider shared understanding


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