scholarly journals Looking for Novel Capsid Protein Multimerization Inhibitors of Feline Immunodeficiency Virus

2018 ◽  
Vol 11 (3) ◽  
pp. 67 ◽  
Author(s):  
Natalia Sierra ◽  
Christelle Folio ◽  
Xavier Robert ◽  
Mathieu Long ◽  
Christophe Guillon ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Feline Immunodeficiency Virus ◽  
Immunodeficiency Virus ◽  
Protein Multimerization

scholarly journals Crystal Structure of the Full-Length Feline Immunodeficiency Virus Capsid Protein Shows an N-Terminal β-Hairpin in the Absence of N-Terminal Proline

Viruses ◽  
2017 ◽  
Vol 9 (11) ◽  
pp. 335 ◽  
Author(s):  
Christelle Folio ◽  
Natalia Sierra ◽  
Marie Dujardin ◽  
Guzman Alvarez ◽  
Christophe Guillon
Keyword(s):  
Crystal Structure ◽  
Capsid Protein ◽  
Feline Immunodeficiency Virus ◽  
Full Length ◽  
Virus Capsid ◽  
Immunodeficiency Virus ◽  
Virus Capsid Protein

Serum neutralization of feline immunodeficiency virus is markedly dependent on passage history of the virus and host system.

1994 ◽  
Vol 68 (7) ◽  
pp. 4572-4579 ◽  
Author(s):  
F Baldinotti ◽  
D Matteucci ◽  
P Mazzetti ◽  
C Giannelli ◽  
P Bandecchi ◽  
...  
Keyword(s):  
Feline Immunodeficiency Virus ◽  
Host System ◽  
Serum Neutralization ◽  
Immunodeficiency Virus ◽  
History Of

scholarly journals Occurrence of feline immunodeficiency virus and feline leukaemia virus in Maputo city and province, Mozambique: a pilot study

2019 ◽  
Vol 5 (2) ◽  
pp. 205511691987087
Author(s):  
Cesaltina CLM Tchamo ◽  
Mónica De Rugeriis ◽  
Emília V Noormahomed
Keyword(s):  
Positive Result ◽  
Feline Immunodeficiency Virus ◽  
Urban Areas ◽  
African Countries ◽  
Leukaemia Virus ◽  
Zoonotic Pathogens ◽  
Test Kit ◽  
Immunodeficiency Virus ◽  
Feline Leukaemia Virus ◽  
Veterinary Faculty

Objectives Feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) are immunosuppressive viruses in cats that increase their susceptibility to zoonotic pathogens. This study aimed to determine the occurrence of one or both viruses, the risk factors associated with infection, and to develop further recommendations. Methods This was a cross-sectional study conducted at the Veterinary Faculty of Eduardo Mondlane University, Mozambique, between March and December 2017, in 145 cats. From each of 145 cats, we took 1.5 ml of blood by jugular puncture for detection of antibodies to FIV and FeLV antigens in whole blood using a commercial test kit, DFV Test FeLV/FIV. Results We found an overall prevalence of 11.0% and 14.5% for FIV antibodies and FeLV antigens, respectively, with four (2.8%) cats coinfected by both pathogens. Male cats were more likely to be infected with FIV (odds ratio [OR] 1.1, 95% confidence interval [CI] 0.3–4.0) compared with female cats. Clinically ill cats were more likely to have a positive result for FeLV antigen infection (OR 18.8, 95% CI 5.2–68.3). Moreover, cats living in suburban areas have a greater chance of a positive result for FeLV infection (OR 3.7, 95% CI 1.4–9.6) compared with cats living in urban areas. Conclusions and relevance FIV and FeLV occur in cats from Maputo and possibly all over the country. Further studies should be conducted in Mozambique and other African countries to define the burden of both pathogens in cats, coinfection with other zoonotic pathogens and the possible role played by the cats on the transmission of zoonotic and opportunistic diseases to humans.

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