scholarly journals OV16 Seroprevalence among Persons with Epilepsy in Onchocerciasis Endemic Regions: A Multi-Country Study

Pathogens ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 847
Author(s):  
Alfred Dusabimana ◽  
Dan Bhwana ◽  
Michel Mandro ◽  
Bruno P. Mmbando ◽  
Joseph N. Siewe Fodjo ◽  
...  
Keyword(s):  
Older Persons ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Antibody Prevalence ◽  
Epidemiological Evidence ◽  
High Prevalence ◽  
Country Study ◽  
Health Zone ◽  
Study Sites ◽  
River Valleys

There is growing epidemiological evidence that onchocerciasis may induce epilepsy. High prevalence of onchocerciasis has been reported in onchocerciasis-meso and hyper-endemic regions. We aimed to determine the OV16 antibody prevalence in persons with epilepsy (PWE) in four onchocerciasis-endemic regions. PWE were identified during studies in Mahenge area (Tanzania), Kitgum and Pader districts (Uganda), the Mbam and Sanaga river valleys (Cameroon), and the Logo health zone (Democratic Republic of Congo). Exposure to Onchocerca volvulus was assessed by testing PWE for OV16 IgG4 antibodies using a rapid diagnostic test. The OV16 seroprevalence among PWE in the four onchocerciasis-endemic study sites ranged from 35.2% to 59.7%. OV16 seroprevalence increased with age until the age of 39 years, after which it decreased drastically. Our study suggests that, in onchocerciasis-endemic regions, epilepsy in young people is often associated with onchocerciasis, while epilepsy in older persons seems unrelated to O. volvulus exposure.

scholarly journals A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo

EBioMedicine ◽  
2021 ◽  
Vol 65 ◽  
pp. 103258 ◽  
Author(s):  
Michael G. Berg ◽  
Ana Olivo ◽  
Barbara J. Harris ◽  
Mary A. Rodgers ◽  
Linda James ◽  
...  
Keyword(s):  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Elite Controllers ◽  
Republic Of Congo ◽  
High Prevalence

scholarly journals Mutual Health Insurance and Access to Care in the Health Zone of Kabinda, Kasai-Oriental, Democratic Republic of Congo (DRC)

OALib ◽  
2017 ◽  
Vol 04 (04) ◽  
pp. 1-11
Author(s):  
Cibangu Kazadi Richard ◽  
Bilonda Mpiana Alphonsine ◽  
Kabengele Mpinga Emmanuel ◽  
Mulewu Ngandu Hippolyte ◽  
Ciamala Mukendi Paul ◽  
...  
Keyword(s):  
Health Insurance ◽  
Access To Care ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Republic Of Congo ◽  
Health Zone

scholarly journals High Prevalence of Thyroid Dysfunction Among Pregnant Women in Lubumbashi, Democratic Republic of Congo

Thyroid ◽  
2014 ◽  
Vol 24 (3) ◽  
pp. 568-575 ◽  
Author(s):  
Laurence Habimana ◽  
Kabange E. Twite ◽  
Chantal Daumerie ◽  
Pierre Wallemacq ◽  
Philippe Donnen ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Republic Of Congo ◽  
High Prevalence

scholarly journals High prevalence and diversity of hepatitis virus in symptomatic patients in Democratic Republic of Congo

2016 ◽  
Vol 2 ◽  
pp. 45
Author(s):  
Sheila Makiala Mandanda ◽  
Frédéric Le Gal ◽  
Nadine Ngwaka ◽  
Berthold Bivigou Mboumba ◽  
Steve Ahuka ◽  
...  
Keyword(s):  
Democratic Republic ◽  
Democratic Republic Of Congo ◽  
Hepatitis Virus ◽  
Republic Of Congo ◽  
High Prevalence

scholarly journals High prevalence rates of antibody to three sandfly fever viruses (Sicilian, Naples and Toscana) among Cypriots

1991 ◽  
Vol 107 (3) ◽  
pp. 685-691 ◽  
Author(s):  
R. Eitrem ◽  
M. Stylianou ◽  
B. Niklasson
Keyword(s):  
Neutralizing Antibodies ◽  
Public Health Problem ◽  
Prevalence Rates ◽  
Antibody Prevalence ◽  
High Prevalence ◽  
Significant Public Health Problem ◽  
Significant Public Health ◽  
History Of ◽  
Study Sites ◽  
Antibody Levels

SUMMARYNeutralizing antibodies to sandfly fever Naples, sandfly fever Sicilian and Toscana viruses were investigated among 479 sera collected from a normal human population in Cyprus. Antibody prevalence rates of 57%, 32% and 20% were found to Naples, Sicilian and Toscana viruses, respectively. The observed frequency of dual and triple infections was higher than would be expected with a random chance of infection. Antibody prevalence rates were similar for men and women for all three viruses tested, but one of two study sites had significantly higher antibody prevalence to Naples and Sicilian viruses than the other. Individuals with antibodies to both Naples and Toscana viruses had higher antibody levels to Naples virus than those with antibodies to Naples virus only. If the antibody prevalence rates found in this study reflect a history of clinical disease as described in the literature, sandfly fever poses a significant public health problem in Cyprus.

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