scholarly journals Evolution and Divergence of H3N8 Equine Influenza Viruses Circulating in the United Kingdom from 2013 to 2015

Pathogens ◽  
2017 ◽  
Vol 6 (1) ◽  
pp. 6 ◽  
Author(s):  
Adam Rash ◽  
Rachel Morton ◽  
Alana Woodward ◽  
Olivia Maes ◽  
John McCauley ◽  
...  
1993 ◽  
Vol 133 (21) ◽  
pp. 515-519 ◽  
Author(s):  
G. Livesay ◽  
T. O'Neill ◽  
D. Hannant ◽  
M. Yadav ◽  
J. Mumford

1999 ◽  
Vol 145 (16) ◽  
pp. 449-452 ◽  
Author(s):  
J. R. Newton ◽  
K. Verheyen ◽  
J. L. N. Wood ◽  
P. J. Yates ◽  
J. A. Mumford

2019 ◽  
Vol 24 (31) ◽  
Author(s):  
Richard Pebody ◽  
Abdelmajid Djennad ◽  
Joanna Ellis ◽  
Nick Andrews ◽  
Diogo F P Marques ◽  
...  

Background In the United Kingdom (UK), in recent influenza seasons, children are offered a quadrivalent live attenuated influenza vaccine (LAIV4), and eligible adults mainly trivalent inactivated vaccine (TIV). Aim To estimate the UK end-of-season 2017/18 adjusted vaccine effectiveness (aVE) and the seroprevalence in England of antibodies against influenza viruses cultured in eggs or tissue. Methods This observational study employed the test-negative case–control approach to estimate aVE in primary care. The population-based seroprevalence survey used residual age-stratified samples. Results Influenza viruses A(H3N2) (particularly subgroup 3C.2a2) and B (mainly B/Yamagata/16/88-lineage, similar to the quadrivalent vaccine B-virus component but mismatched to TIV) dominated. All-age aVE was 15% (95% confidence interval (CI): −6.3 to 32) against all influenza; −16.4% (95% CI: −59.3 to 14.9) against A(H3N2); 24.7% (95% CI: 1.1 to 42.7) against B and 66.3% (95% CI: 33.4 to 82.9) against A(H1N1)pdm09. For 2–17 year olds, LAIV4 aVE was 26.9% (95% CI: −32.6 to 59.7) against all influenza; −75.5% (95% CI: −289.6 to 21) against A(H3N2); 60.8% (95% CI: 8.2 to 83.3) against B and 90.3% (95% CI: 16.4 to 98.9) against A(H1N1)pdm09. For ≥ 18 year olds, TIV aVE against influenza B was 1.9% (95% CI: −63.6 to 41.2). The 2017 seroprevalence of antibody recognising tissue-grown A(H3N2) virus was significantly lower than that recognising egg-grown virus in all groups except 15–24 year olds. Conclusions Overall aVE was low driven by no effectiveness against A(H3N2) possibly related to vaccine virus egg-adaption and a new A(H3N2) subgroup emergence. The TIV was not effective against influenza B. LAIV4 against influenza B and A(H1N1)pdm09 was effective.


2005 ◽  
Vol 156 (12) ◽  
pp. 367-371 ◽  
Author(s):  
C. Edlund Toulemonde ◽  
J. Daly ◽  
T. Sindle ◽  
P. M. Guigal ◽  
J. C. Audonnet ◽  
...  

1977 ◽  
Vol 79 (1) ◽  
pp. 77-87 ◽  
Author(s):  
Marguerite S. Pereira ◽  
Pratima Chakraverty

SUMMARYThe extensive laboratory investigations of respiratory disease in the U.K. over many years have demonstrated the frequency with which influenza viruses, both A and B, are found each winter. Only rarely are none isolated.These findings correlate well with other indicators of influenza such as increases in sickness benefit claims and in deaths attributed to influenza and pneumonia.However, outside these demonstrable peaks of incidence influenza viruses have been found to circulate over considerably longer periods often first appearing as early as November and continuing through to April or even May. But there has been no regular or predictablepattern determined.The period of 1968–76 has seen a series of differently developing influenza winter epidemics caused by a series of the H3N2 virus. The contributions of virus isolation and serology to influenza surveillance is discussed.


2009 ◽  
pp. 1-6 ◽  
Author(s):  
Nishan Fernando ◽  
Gordon Prescott ◽  
Jennifer Cleland ◽  
Kathryn Greaves ◽  
Hamish McKenzie

1990 ◽  
Vol 35 (8) ◽  
pp. 800-801
Author(s):  
Michael F. Pogue-Geile

Sign in / Sign up

Export Citation Format

Share Document