scholarly journals Examining the Relationship between Toxoplasma gondii and Seropositivity and Serointensity and Depression in Adults from the United Kingdom and the United States: A Cross-Sectional Study

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1101
Author(s):  
Shawn D. Gale ◽  
Lance D. Erickson ◽  
Bruce L. Brown ◽  
Dawson W. Hedges

Infecting approximately one-third of the world’s population, the neurotropic protozoan Toxoplasma gondii has been associated with cognition and several neuropsychiatric diseases including schizophrenia and bipolar disorder. Findings have been mixed, however, about the relationship between Toxoplasma gondii and depression, with some studies reporting positive associations and others finding no associations. To further investigate the association between Toxoplasma gondii and depression, we used data from the UK Biobank and the National Health and Examination Survey (NHANES). Results from adjusted multiple-regression modeling showed no significant associations between Toxoplasma gondii and depression in either the UK Biobank or NHANES datasets. Further, we found no significant interactions between Toxoplasma gondii and age, sex, educational attainment, and income in either dataset that affected the association between Toxoplasma gondii and depression. These results from two community-based datasets suggest that in these samples, Toxoplasma gondii is not associated with depression. Differences between our findings and other findings showing an association between Toxoplasma gondii and depression could be due to several factors including differences in socioeconomic variables, differences in Toxoplasma gondii strain, and use of different covariates in statistical modeling.

Author(s):  
Heather Mechler ◽  
Kathryn Coakley ◽  
Marygold Walsh-Dilley ◽  
Sarita Cargas

In recent years, researchers have increasingly focused on the experience of food insecurity among students at higher education institutions. Most of the literature has focused on undergraduates in the eastern and midwestern regions of the United States. This cross-sectional study of undergraduate, graduate, and professional students at a Minority Institution in the southwestern United States is the first of its kind to explore food insecurity among diverse students that also includes data on gender identity and sexual orientation. When holding other factors constant, food-insecure students were far more likely to fail or withdraw from a course or to drop out entirely. We explore the role that higher education can play in ensuring students’ basic needs and implications for educational equity.


2018 ◽  
Vol 54 (1) ◽  
pp. 28-72
Author(s):  
Katarzyna Hamer ◽  
Sam McFarland ◽  
Barbara Czarnecka ◽  
Agnieszka Golińska ◽  
Liliana Manrique Cadena ◽  
...  

Although the term “ethnic group” (EG) is often used in social studies, its definition differs among researchers. Moreover, little is known about ordinary people’s subjective understanding of this term, even though it is often used in social discourse. We examined this issue in a cross-sectional study of 273 American, British, Mexican, and Polish students using an open-ended questions approach. Results revealed cultural differences in patterns of “ethnic group” definitions across the four countries. U.S. respondents predominantly connected EG to “race”; British participants frequently related it to “race,” but more often to “common culture” and “customs/traditions.” Both latter categories were overwhelmingly dominant in Mexico and Poland. However, “nation,” “shared history,” “religion,” “language,” and “territory” were also very popular as EG understandings in Poland. Although most participants used the newer definition of EG (referring to all groups in a society, including minority and majority groups), a few in each country used the term only to refer to minorities and people different from themselves (an older, “minus one” definition). Unexpected definitions of EG also appeared (e.g., people having similar hobbies, having similar work goals, or living in the same city). The results also indicate that for the United States, the United Kingdom, and Mexico, “ethnic group” was more a subgroup within a nation, whereas in Poland, they represented the same level of categorization. The theoretical and practical implications of our findings are discussed.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Anjali Kumar ◽  
Dana Cernigliaro ◽  
Mary E. Northridge ◽  
Yinxiang Wu ◽  
Andrea B. Troxel ◽  
...  

Abstract Background Interest in aqueous silver diamine fluoride (SDF) has been growing as a treatment for caries arrest. A cross-sectional study was conducted to identify factors associated with caregiver acceptance of SDF treatment for children presenting with caries at 8 Federally Qualified Health Centers. The study purpose was to examine associations between caregiver acceptance of SDF treatment for children with caries and (1) sociodemographic and acculturation characteristics of caregivers and (2) clinical assessments of the children by dentists. Methods A caregiver survey collected information on: sociodemographic characteristics; acculturation characteristics, measured using the validated Short Acculturation Scale for Hispanics (SASH); perceived benefits and barriers of SDF treatment, including caregiver comfort; and perceived health-related knowledge. Chart reviews were conducted to assess: the medical / dental insurance of pediatric patients; cumulative caries experience, measured using decayed, missing, filled teeth total scores (dmft / DMFT); whether operating room treatment was needed; and a record of caregiver acceptance of SDF treatment (the outcome measure). Standard logistic regression models were developed for caregiver acceptance of SDF treatment for their children as the binary outcome of interest (yes / no) to calculate unadjusted odds ratios (OR) and adjusted ORs for covariates of interest. Results Overall, 434 of 546 caregivers (79.5%) accepted SDF treatment for their children. A U-shaped relationship between caregiver odds of accepting SDF treatment and age group of pediatric patients was present, where caregivers were most likely to accept SDF treatment for their children who were either < 6 years or 9–14 years, and least likely to accept SDF treatment for children 6 to < 9 years. The relationship between acculturation and caregiver acceptance of SDF treatment depended upon whether or not caregivers were born in the United States: greater acculturation was associated with caregiver acceptance of SDF treatment among caregivers born in this country, and lower acculturation was associated with caregiver acceptance of SDF treatment among caregivers born elsewhere. Conclusions Caregiver acceptance of SDF treatment is high; child’s age and caregiver comfort are associated with acceptance. Providers need to communicate the risks and benefits of evidence-based dental treatments to increasingly diverse caregiver and patient populations.


Rheumatology ◽  
2019 ◽  
Vol 58 (12) ◽  
pp. 2137-2142 ◽  
Author(s):  
Lyn D Ferguson ◽  
Rosemary Brown ◽  
Carlos Celis-Morales ◽  
Paul Welsh ◽  
Donald M Lyall ◽  
...  

AbstractObjectivesTo determine the independent association of central adiposity, assessed by waist circumference, with odds of psoriasis, PsA and RA prevalence after controlling for general adiposity (BMI).MethodsA cross-sectional study of UK Biobank participants aged 40–70 years was performed. Logistic regression was used to calculate the odds of psoriasis, PsA and RA occurrence compared with controls without these conditions by waist circumference, adjusting for covariates: age, sex, smoking status, socioeconomic deprivation and self-reported physical activity (Model 1), followed additionally by BMI (Model 2).ResultsA total of 502 417 participants were included; 5074 with psoriasis (1.02%), 905 with PsA (0.18%), 5532 with RA (1.11%) and 490 906 controls without these conditions. Adjusted odds ratios (ORs) (Model 1) for psoriasis, PsA and RA, per s.d. (13.5 cm) higher waist circumference were 1.20 (95% CI 1.16, 1.23), 1.30 (95% CI 1.21, 1.39) and 1.21 (95% CI 1.17, 1.24), respectively (all P < 0.001). These ORs remained significant after further adjustment for BMI (Model 2) in psoriasis [OR 1.19 (95% CI 1.12, 1.27), P < 0.001] and RA [OR 1.19 (95% CI 1.12, 1.26), P < 0.001], but not in PsA [OR 1.11 (95% CI 0.95, 1.29), P = 0.127].ConclusionCentral adiposity as measured by waist circumference is associated with greater odds of psoriasis and RA prevalence after adjustment for confounders and for BMI. Our findings add support for central adiposity as a long-term clinically relevant component of these conditions.


2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Clint Pinion

More than five thousand workers lost their lives in 2018 due to occupational incidents. Research suggests that increased job control and safety citizenship can help mitigate occupational incidents. This study aims to answer the following research question: Does a relationship exist between the behavior of reporting occupational injuries and both job control and safety citizenship? This exploratory cross-sectional study used an employee perception questionnaire to examine the behavior of reporting occupational injuries, employee job control, and six safety citizenship sub-dimensions of action (i.e. stewardship, civic virtue, whistleblowing, initiating safety-related change, voice, and helping) at two companies in the Midwestern region of the United States. The survey consisted of 34 items and used a 5-point Likert Scale to quantify the data gathered along with other demographic variables. An ordinal logistic regression analysis to investigate the relationship between the behavior of reporting occupational injuries, job control, and the six sub-dimensions of safety citizenship was conducted. Results indicate that job control ( X2 = 8.512, df = 1, p < 0.05) and whistleblowing (X2 = 4.836, df = 1, p < 0.05) predict the behavior of occupational injury reporting.


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