scholarly journals Host Diversity and Potential Transmission Pathways of SARS-CoV-2 at the Human-Animal Interface

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 180 ◽  
Author(s):  
Hayden D. Hedman ◽  
Eric Krawczyk ◽  
Yosra A. Helmy ◽  
Lixin Zhang ◽  
Csaba Varga
Keyword(s):  
Public Health ◽  
Close Contact ◽  
Natural Infection ◽  
Emerging Infectious Diseases ◽  
Reservoir Host ◽  
Host Susceptibility ◽  
Public Health Issue ◽  
Severe Illness ◽  
Host Diversity ◽  
Transmission Pathways

Emerging infectious diseases present great risks to public health. The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease 2019 (COVID-19), has become an urgent public health issue of global concern. It is speculated that the virus first emerged through a zoonotic spillover. Basic research studies have suggested that bats are likely the ancestral reservoir host. Nonetheless, the evolutionary history and host susceptibility of SARS-CoV-2 remains unclear as a multitude of animals has been proposed as potential intermediate or dead-end hosts. SARS-CoV-2 has been isolated from domestic animals, both companion and livestock, as well as in captive wildlife that were in close contact with human COVID-19 cases. Currently, domestic mink is the only known animal that is susceptible to a natural infection, develop severe illness, and can also transmit SARS-CoV-2 to other minks and humans. To improve foundational knowledge of SARS-CoV-2, we are conducting a synthesis review of its host diversity and transmission pathways. To mitigate this COVID-19 pandemic, we strongly advocate for a systems-oriented scientific approach that comprehensively evaluates the transmission of SARS-CoV-2 at the human and animal interface.

scholarly journals Ecology of Bacterial Pathogens Associated With Public Waste Dumpsites and their Public Health Consequences

2018 ◽  
Vol 1 (1) ◽  
Keyword(s):  
Public Health ◽  
Prevalence Rate ◽  
Ph Value ◽  
Close Contact ◽  
Soil Samples ◽  
Public Health Issue ◽  
Health Consequences ◽  
Deep Soil ◽  
Dump Site ◽  
Significant Difference

Human societies generates large amount of waste routinely thus, waste has increasingly becomes a huge public health issue, if we must check the sporadic upsurge of epidemic outbreaks in our communities. Nonetheless, indiscriminate dumping of waste breeds different arrays of microorganisms that have been implicated with myriads of health hazards with massive public health consequences. Therefore; there is urgent need to understand the pathogens that are associated with a public waste dump site and its Public Health implications. This observational study explored the collection of two soil samples (surface and deep), from three different sampling stations. The samples were analysed for pH and aerobic heterotrophic bacterial counts using the standard analytic procedures. Both parametric (unpaired two sample t-test) and non-parametric (Mann Whitney U, Wilcoxon and Kruskalwallis) test statistics were performed at 5% significance level. Also descriptive statistics of frequency, percentage, mean and standard deviation and prevalence rate were also explored. The statistical analysis was done using Graphpad calculator and SPSS version 21. The mean pH value of the soils ranged from pH 6.78±0.01to 7.30±0.01with no significant difference (P > 0.05) between soil levels. Heterotrophic bacterial count ranged from 1.6x108 ±1.0x106 cfu/g soil to 4.4x108 ±5.8x106 cfu/g soil. However, there was a significant difference (P < 0.05) between surface and deep soil samples. However, frequency distribution and prevalence rate revealed the probable isolates in a decreasing prevalence order Nonetheless, of Bacillus spp52 (29.4%)> Proteus spp50 (28.3%)>Klebsiellaspp37 (20.9%)>Staph auerus27 (15.3%)>Pseudomasspp6 (3.4%)> Staph. Spp5 (2.8%). The common diseases caused by these microbes range from zoonotic diseases such as Anthrax to urinary trait infections, food borne infection, wound infection and septicaemia respectively. It is therefore very critical that students and University staff in close contact with any of these dumpsites with these associated public health pathogens are at risk of acquiring the above illness thus, there is urgent need for proper waste management and smart sanitation strategy intervention in the region.

Socio-demographic and Clinical Characteristics of Patient with Thyroid Cancer

2020 ◽  
Vol 11 (1) ◽  
pp. 54-58
Author(s):  
AKM Farhad Hossain ◽  
Md Mahmudur Rahman Siddiqui ◽  
Sayada Fatema Khatun
Keyword(s):  
Public Health ◽  
Thyroid Cancer ◽  
Clinical Characteristics ◽  
Family Income ◽  
Ethical Issues ◽  
Endocrine System ◽  
Public Health Problem ◽  
Follicular Carcinoma ◽  
Public Health Issue ◽  
Cross Sectional

Background: Thyroid cancer is the most common malignant disease in endocrine system. It is an emerging public health issue associated with burden on the family, community and the nation. The aim of this study is to determine the socio-demographic and clinical characteristics of patient with thyroid cancer attending in tertiary hospital. Methods: This cross sectional study was conducted among 246 thyroid cancer patients in two tertiary hospitals of Dhaka city from 01 July 2018 to 30 June 2019. The subjects were selected purposively following specific selection criteria and maintaining ethical issues. Data were collected by face to face interview using a semi-structured questionnaire and checklist. Data were analyzed by the statistical package for the social science (SPSS) version 23. Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (Range 14-70 years) and mean (± SD) monthly family income was Tk. 17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Various clinical presentations included visible neck swelling in 225 (91.5%), swollen lymph node in 103 (41.9%), pain 90 (36.6%), Difficulties in swallowing 87 (35.4%), Hoarseness of voice in 141 (57.3%), cough along with swelling 47(19.1%), Difficulties in breathing due to swelling in 13(5.3%) of the patients. Conclusion: Incidence of thyroid cancer has increased worldwide specially in female patients in 3rd and 4th decades of life. As thyroid cancer is a growing public health problem in Bangladesh, proper screening and early diagnostic facilities at all level should be available to measure its actual burden in the country. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 54-58

Identifying changes in trends in the age standardized incidence of melanoma in Australia

2019 ◽  
Vol 3 (4) ◽  
pp. 250-252 ◽  
Author(s):  
David M Hille
Keyword(s):  
Public Health ◽  
Linear Regression ◽  
Iterative Process ◽  
Linear Trend ◽  
Piecewise Linear ◽  
Health Issue ◽  
Public Health Issue ◽  
Piecewise Linear Regression ◽  
Significant Public Health ◽  
Males And Females

ObjectiveTo identify changes in the linear trend of the age-standardized incidence of melanoma in Australia for all persons, males, and females. MethodsA two-piece piecewise linear regression was fitted to the data. The piecewise breakpoint varied through an iterative process to determine the model that best fits the data.ResultsStatistically significant changes in the trendof the age-standardized incidence of melanoma in Australia were found for all persons, males, and females. The optimal breakpoint for all persons and males was at 1998. For females, the optimal breakpoint was at 2005. The trend after these breakpoints was flatter than prior to the breakpoints, but still positive.ConclusionMelanoma is a significant public health issue in Australia. Overall incidence continues to increase. However, the rate at which the incidence is increasing appears to be decreasing.

Biosecurity and Public Health Ethics Issues Raised by Biological Threats

2019 ◽  
pp. 773-785
Author(s):  
Nicholas Evans ◽  
Thomas Inglesby
Keyword(s):  
Public Health ◽  
Resource Allocation ◽  
Infectious Diseases ◽  
Ethical Issues ◽  
Emerging Infectious Diseases ◽  
Biological Weapon ◽  
Ethical Values ◽  
Dual Use ◽  
Health Concerns ◽  
Trade Offs

This chapter introduces ethical issues that arise in the context of biosecurity: policies and actions intended to prevent the development or emergence, or mitigate the consequences, of serious biological threats. These threats could include deliberate biological weapon attacks (bioterrorism), pandemics, emerging infectious diseases, or major laboratory accidents. The basic values that underpin these public health concerns are first introduced. Ethical issues that arise before, during, and following a biosecurity crisis are then examined, including issues of resource allocation, dual-use research, and the possibility of quarantine. Their resolution requires trade-offs among different ethical values, including utility, fairness, and liberty.

scholarly journals Ocular manifestations of emerging viral diseases

Eye ◽  
2021 ◽  
Author(s):  
Ashwin Venkatesh ◽  
Ravi Patel ◽  
Simran Goyal ◽  
Timothy Rajaratnam ◽  
Anant Sharma ◽  
...  
Keyword(s):  
Public Health ◽  
Infectious Diseases ◽  
Influenza A ◽  
Emerging Infectious Diseases ◽  
Global Scale ◽  
Viral Diseases ◽  
Valley Fever ◽  
Ocular Manifestations ◽  
Influenza A H1n1 ◽  
Emerging Viral Diseases

AbstractEmerging infectious diseases (EIDs) are an increasing threat to public health on a global scale. In recent times, the most prominent outbreaks have constituted RNA viruses, spreading via droplets (COVID-19 and Influenza A H1N1), directly between humans (Ebola and Marburg), via arthropod vectors (Dengue, Zika, West Nile, Chikungunya, Crimean Congo) and zoonotically (Lassa fever, Nipah, Rift Valley fever, Hantaviruses). However, specific approved antiviral therapies and vaccine availability are scarce, and public health measures remain critical. Patients can present with a spectrum of ocular manifestations. Emerging infectious diseases should therefore be considered in the differential diagnosis of ocular inflammatory conditions in patients inhabiting or returning from endemic territories, and more general vigilance is advisable in the context of a global pandemic. Eye specialists are in a position to facilitate swift diagnosis, improve clinical outcomes, and contribute to wider public health efforts during outbreaks. This article reviews those emerging viral diseases associated with reports of ocular manifestations and summarizes details pertinent to practicing eye specialists.

scholarly journals The Evolution of the Healthy Brain Initiative

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 720-720
Author(s):  
Lisa McGuire
Keyword(s):  
Public Health ◽  
Population Based ◽  
Public Health Issue ◽  
Dementia Caregivers ◽  
Local Public Health ◽  
Success Stories ◽  
Road Map ◽  
Indian Country ◽  
State And Local ◽  
Map Series

Abstract The Healthy Brain Initiative (HBI) seeks to advance public health awareness of and action on ADRD as a public health issue. The HBI Road Map Series, State and Local Public Health Partnerships to Address Dementia: The 2018–2023 Road Map (S&L RM) and Road Map for Indian Country (RMIC), provide the public health with concrete steps to respond to the growing burden of ADRD in communities, consistent with the aim of the Building Our Largest Dementia (BOLD) Infrastructure for Alzheimer’s Act (P.L. 115-406). This series of RMs for state, local, and tribal public health provide flexible menus of actions to address cognitive health, including ADRD, and support for dementia caregivers with population-based approaches. This session will describe how the initiative evolved over the past 15 years including policy and implementation success stories.

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