scholarly journals Hepatic Retinyl Ester Hydrolases and the Mobilization of Retinyl Ester Stores

Nutrients ◽  
2016 ◽  
Vol 9 (1) ◽  
pp. 13 ◽  
Author(s):  
Lukas Grumet ◽  
Ulrike Taschler ◽  
Achim Lass
Keyword(s):  
Retinyl Ester ◽  
Ester Hydrolases

Bile salt independent retinyl ester hydrolases in the bovine eye

1992 ◽  
Vol 28 (1) ◽  
pp. 121-125 ◽  
Author(s):  
Andrew T.C. Tsin ◽  
Douglas W. Malsbury
Keyword(s):  
Bile Salt ◽  
Retinyl Ester ◽  
Ester Hydrolases

scholarly journals Retinyl ester hydrolases and their roles in vitamin A homeostasis

2012 ◽  
Vol 1821 (1) ◽  
pp. 113-123 ◽  
Author(s):  
Renate Schreiber ◽  
Ulrike Taschler ◽  
Karina Preiss-Landl ◽  
Nuttaporn Wongsiriroj ◽  
Robert Zimmermann ◽  
...  
Keyword(s):  
Vitamin A ◽  
Retinyl Ester ◽  
Ester Hydrolases

Retinyl ester hydrolases in retinal pigment epithelium

1991 ◽  
Vol 288 (2) ◽  
pp. 572-577 ◽  
Author(s):  
Maria C. Gueli ◽  
Concetta M.A. Nicotra ◽  
Anna M. Pintaudi ◽  
Alessandra Paganini ◽  
Leonardo Pandolfo ◽  
...  
Keyword(s):  
Retinal Pigment Epithelium ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Retinyl Ester ◽  
Ester Hydrolases

scholarly journals Carboxylic Ester Hydrolases in Bacteria: Active Site, Structure, Function and Application

Crystals ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 597 ◽  
Author(s):  
Changsuk Oh ◽  
T. Doohun Kim ◽  
Kyeong Kyu Kim
Keyword(s):  
Acyl Chain ◽  
Data Bank ◽  
Industrial Applications ◽  
Head Group ◽  
Carboxylic Ester ◽  
Site Structure ◽  
Domains Of Life ◽  
Carboxylic Esters ◽  
Hydrolysis Of ◽  
Ester Hydrolases

Carboxylic ester hydrolases (CEHs), which catalyze the hydrolysis of carboxylic esters to produce alcohol and acid, are identified in three domains of life. In the Protein Data Bank (PDB), 136 crystal structures of bacterial CEHs (424 PDB codes) from 52 genera and metagenome have been reported. In this review, we categorize these structures based on catalytic machinery, structure and substrate specificity to provide a comprehensive understanding of the bacterial CEHs. CEHs use Ser, Asp or water as a nucleophile to drive diverse catalytic machinery. The α/β/α sandwich architecture is most frequently found in CEHs, but 3-solenoid, β-barrel, up-down bundle, α/β/β/α 4-layer sandwich, 6 or 7 propeller and α/β barrel architectures are also found in these CEHs. Most are substrate-specific to various esters with types of head group and lengths of the acyl chain, but some CEHs exhibit peptidase or lactamase activities. CEHs are widely used in industrial applications, and are the objects of research in structure- or mutation-based protein engineering. Structural studies of CEHs are still necessary for understanding their biological roles, identifying their structure-based functions and structure-based engineering and their potential industrial applications.

Carboxyl Ester Lipase Overexpression in Rat Hepatoma Cells and CEL Deficiency in Mice Have No Impact on Hepatic Uptake or Metabolism of Chylomicron-Retinyl Ester†

Biochemistry ◽  
1999 ◽  
Vol 38 (13) ◽  
pp. 4150-4156 ◽  
Author(s):  
Ariëtte M. van Bennekum ◽  
Ling Li ◽  
Roseann Piantedosi ◽  
Raanan Shamir ◽  
Silke Vogel ◽  
...  
Keyword(s):  
Hepatic Uptake ◽  
Hepatoma Cells ◽  
Retinyl Ester ◽  
Rat Hepatoma ◽  
Rat Hepatoma Cells
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