scholarly journals Association between Parent and Child Dietary Sodium and Potassium Intakes as Assessed by 24-h Urinary Excretion

Nutrients ◽  
2016 ◽  
Vol 8 (4) ◽  
pp. 191 ◽  
Author(s):  
Carrie Service ◽  
Carley Grimes ◽  
Lynn Riddell ◽  
Feng He ◽  
Karen Campbell ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Dietary Sodium ◽  
Sodium And Potassium

Abstract P050: Reproducibility of Blood Pressure Responses to Dietary Sodium and Potassium Interventions: the GenSalt Study

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Jiang He ◽  
Dongfeng Gu ◽  
Jichun Chen ◽  
Qi Zhao ◽  
Lydia A Bazzano ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Urinary Excretion ◽  
Dietary Intervention ◽  
Correlation Coefficients ◽  
Dietary Sodium ◽  
High Sodium ◽  
Low Sodium ◽  
Potassium Supplementation ◽  
Study Participants ◽  
Sodium And Potassium

Blood pressure (BP) responses to dietary sodium and potassium interventions vary among individuals (salt- and potassium-sensitivity). However, it is unknown whether salt- and/or potassium-sensitivity is a reproducible trait. We repeated the dietary sodium and potassium intervention among 488 Han Chinese who participated in the Genetic Epidemiology Network of Salt Sensitivity (GenSalt) four years after the original dietary intervention. The same dietary intervention protocol, which included a 7-day low sodium-feeding (51.3 mmol/day), a 7-day high sodium-feeding (307.8 mmol/day), and a 7-day high sodium-feeding with an oral potassium supplementation (60 mmol/day), was applied in both the original and repeated studies. Three BP measurements were obtained during each of the 3 days of baseline observation and on days 5, 6, and 7 of each intervention period. Three timed urinary samples were collected to measure sodium and potassium excretion at baseline and during each intervention phase. On average, study participants were 39.7 years old and 49.4% of them were male. Study participants had a mean body mass index of 23.7 kg/m 2 , systolic BP of 118.1 mmHg, diastolic BP of 74.4 mmHg, urinary excretion of sodium of 258.8 mmol/24-hrs, and urinary excretion of potassium of 38.8 mmol/24-hrs. The results from the 24-h urinary excretions of sodium and potassium showed excellent compliance with the study diet. BP responses to dietary intervention in the original and repeated studies were highly correlated. For example, the correlation coefficients for systolic BP between original and repeated studies were 0.7681 at baseline, 0.7902 during low-sodium, 0.8045 during high-sodium, and 0.8232 during high-sodium and potassium supplementation intervention (all p<0.0001). The correlation coefficients for systolic BP changes between original and repeated studies were 0.3659 from baseline to low-sodium, 0.3655 from low to high-sodium, and 0.2850 from high-sodium to potassium supplementation (all p<0.0001). These data indicate that BP responses to dietary sodium and potassium intervention are reproducible traits. Furthermore, our study suggests that identification of individuals who are more sensitive to dietary sodium and potassium intake may improve the efficiency of targeted dietary intervention for hypertension prevention among high-risk individuals.

scholarly journals Assessment of Sodium and Potassium Intakes in Children Aged 6 to 18 Years by 24 h Urinary Excretion in City of Rabat, Morocco

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Naima Saeid ◽  
Mohammed Elmzibri ◽  
Abdeslam Hamrani ◽  
Qandoussi Latifa ◽  
Hakim Belghiti ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Salt Intake ◽  
Sodium Intake ◽  
Its Region ◽  
Cost Effective ◽  
Dietary Sodium ◽  
Noncommunicable Diseases ◽  
High Sodium ◽  
High Level ◽  
Sodium And Potassium

Background. The incidence of noncommunicable diseases (NCDs) has greatly increased, mainly due to high level of dietary sodium. Thus, reduction of sodium intake in population has been recognized as one of the most cost-effective strategies to reduce NCDs. The aim of this study was to estimate sodium and potassium consumption in a sample of Moroccan children as a baseline study to implement national strategy for salt intake reduction. Methods. The study was conducted on 131 children aged 6–18 years recruited from Rabat and its region. Sodium excretion and potassium excretion were measured on 24 h urinary collection, and the creatinine excretion was used to validate completeness of urine collections. Results. The average of urinary sodium was 2235.3 ± 823.2 mg/day, and 50% of children consume more than 2 g/d of sodium (equivalent to 5 g/day of salt), recommended by the WHO. However, daily urinary excretion of potassium was 1431 ± 636.5 mg/day, and 75% of children consume less than adequate intake. Sodium consumption increased significantly with age. Of particular interest, 46.7% of children aged 6–8 years and 49.3% of children aged 9–13 years consume more than the corresponding upper limits. Conclusions. Children have high sodium and low potassium status. There is evidence of the urgent need to implement a strategy for reduction of dietary sodium intake in Morocco.

Daily dietary sodium and potassium intake in Belgium, using duplicate portion sampling

1999 ◽  
Vol 209 (1) ◽  
pp. 63-67 ◽  
Author(s):  
Rudy Van Cauwenbergh ◽  
Peter Hendrix ◽  
H. J. Robberecht ◽  
Hendrik A. Deelstra
Keyword(s):  
Dietary Sodium ◽  
Potassium Intake ◽  
Duplicate Portion Sampling ◽  
Duplicate Portion ◽  
Sodium And Potassium

Comparative Study of Glucose and Fructose Metabolism in Infants with Reference to Utilization and to the Accumulation of Glycolytic Intermediates

PEDIATRICS ◽  
1958 ◽  
Vol 22 (4) ◽  
pp. 773-773
Keyword(s):  
Urinary Excretion ◽  
Urine Excretion ◽  
Acid Base ◽  
Rapid Infusion ◽  
Acid Base Equilibrium ◽  
Glycolytic Intermediates ◽  
Acid Metabolites ◽  
Lactate And Pyruvate ◽  
Maintenance Requirements ◽  
Sodium And Potassium

Recently considerable interest has been directed at the comparative rates of utilization of glucose and fructose, administered intravenously. The present study was designed to carry out such a comparison using intakes of the carbohydrates which would provide sufficient calories to meet the maintenance requirements. The observations included a comparison of the extent of accumulation of certain acid metabolites and disturbances of the acid-base equilibrium which result from the rapid infusion of glucose and fructose. It was found that infusions of glucose and fructose in solution with electrolytes at 1 gm/kg/hr enabled both sugars to be utilized completely, without significant differences in the excretion of water, sodium and potassium. When the sugars were infused at a rate of 2 gm/kg/hr, 20% of the glucose and 9.9% of the fructose were excreted in the urine. Excretion of sodium in the urine with infusions of glucose led to loss of 79% of the intake, while for fructose the urinary excretion was 127% of intake, although no significant differences in excretion of water and potassium were noted. Infusions of fructose were accompanied by much greater increases of lactate and pyruvate in the blood than were caused by infusions of glucose. The urinary excretion of lactic acid was also greater with fructose than with glucose. It is stated that the superior utilization of fructose at rapid rates of infusion is not entirely advantageous because of the accompanying acidosis, which is of sufficient severity to make limitation of the rate of its infusion advisable.

scholarly journals Measurement Error Corrected Sodium and Potassium Intake Estimation Using 24-Hour Urinary Excretion

Hypertension ◽  
2014 ◽  
Vol 63 (2) ◽  
pp. 238-244 ◽  
Author(s):  
Ying Huang ◽  
Linda Van Horn ◽  
Lesley F. Tinker ◽  
Marian L. Neuhouser ◽  
Laura Carbone ◽  
...  
Keyword(s):  
Measurement Error ◽  
Urinary Excretion ◽  
Potassium Intake ◽  
Sodium And Potassium

Dietary Sodium, Potassium, and Sodium to Potassium Ratio in Patients With Systemic Lupus Erythematosus

2022 ◽  
pp. 109980042110654
Author(s):  
María Correa-Rodríguez ◽  
Sara DelOlmo-Romero ◽  
Gabriela Pocovi-Gerardino ◽  
José-Luis Callejas-Rubio ◽  
Raquel Ríos-Fernández ◽  
...  
Keyword(s):  
Disease Activity ◽  
Sodium Intake ◽  
Dietary Sodium ◽  
Complement C3 ◽  
Systemic Lupus ◽  
Sodium Potassium ◽  
Complement C4 ◽  
Potassium Intake ◽  
Dietary Potassium ◽  
Sodium And Potassium

Purpose: The aim of this study was to investigate the association between dietary sodium, potassium, and sodium:potassium ratio and clinical disease activity parameters, damage accrual, and cardiovascular disease risk factors in a population of patients with systemic lupus erythematous (SLE). Research design and study sample: A cross-sectional study including a total of 280 patients was conducted (90.4% females; mean age 46.9 ± 12.85 years). Data collection: The SLE Disease Activity Index (SLEDAI-2K) and the SDI Damage Index were used to assess disease activity and disease-related damage, respectively. A 24-hour diet recall was used to estimate dietary intake of sodium and potassium. Results: Dietary sodium intake was significantly associated with anti-dsDNA ( β  =  −.005; 95% CI [.002 .008]; p = .001) and complement C4 level ( β  =  −.002; 95% CI [−.003, .000]; p = .039). Dietary potassium intake was also significantly associated with complement C3 level ( β  =  −.004; 95% CI [−.007, −.001]; p = .021). Multiple logistic regression models revealed a positive association between dietary sodium intake and the risk of having hsCRP > 3 ( p = .005) and an inverse association between dietary potassium intake and the risk of having hsCRP > 3 ( p = .004). Conclusions: SLE patients with higher dietary sodium and lower dietary potassium intakes had an increased risk of higher hsCRP. Dietary sodium intake was significantly associated with anti-dsDNA and complement C4 level, while dietary potassium intake was associated with complement C3 level, supporting that dietary sodium and potassium intakes might play a key role in markers related to disease activity in SLE patients.

scholarly journals Joint association of urinary sodium and potassium excretion with cardiovascular events and mortality: prospective cohort study

BMJ ◽  
2019 ◽  
pp. l772 ◽  
Author(s):  
Martin O’Donnell ◽  
Andrew Mente ◽  
Sumathy Rangarajan ◽  
Matthew J McQueen ◽  
Neil O’Leary ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Sodium Excretion ◽  
Cardiovascular Events ◽  
Sodium Intake ◽  
Urinary Sodium ◽  
Potassium Excretion ◽  
High Potassium ◽  
High Sodium ◽  
Low Sodium ◽  
Sodium And Potassium

AbstractObjectiveTo evaluate the joint association of sodium and potassium urinary excretion (as surrogate measures of intake) with cardiovascular events and mortality, in the context of current World Health Organization recommendations for daily intake (<2.0 g sodium, >3.5 g potassium) in adults.DesignInternational prospective cohort study.Setting18 high, middle, and low income countries, sampled from urban and rural communities.Participants103 570 people who provided morning fasting urine samples.Main outcome measuresAssociation of estimated 24 hour urinary sodium and potassium excretion (surrogates for intake) with all cause mortality and major cardiovascular events, using multivariable Cox regression. A six category variable for joint sodium and potassium was generated: sodium excretion (low (<3 g/day), moderate (3-5 g/day), and high (>5 g/day) sodium intakes) by potassium excretion (greater/equal or less than median 2.1 g/day).ResultsMean estimated sodium and potassium urinary excretion were 4.93 g/day and 2.12 g/day, respectively. After a median follow-up of 8.2 years, 7884 (6.1%) participants had died or experienced a major cardiovascular event. Increasing urinary sodium excretion was positively associated with increasing potassium excretion (unadjusted r=0.34), and only 0.002% had a concomitant urinary excretion of <2.0 g/day of sodium and >3.5 g/day of potassium. A J-shaped association was observed of sodium excretion and inverse association of potassium excretion with death and cardiovascular events. For joint sodium and potassium excretion categories, the lowest risk of death and cardiovascular events occurred in the group with moderate sodium excretion (3-5 g/day) and higher potassium excretion (21.9% of cohort). Compared with this reference group, the combinations of low potassium with low sodium excretion (hazard ratio 1.23, 1.11 to 1.37; 7.4% of cohort) and low potassium with high sodium excretion (1.21, 1.11 to 1.32; 13.8% of cohort) were associated with the highest risk, followed by low sodium excretion (1.19, 1.02 to 1.38; 3.3% of cohort) and high sodium excretion (1.10, 1.02 to 1.18; 29.6% of cohort) among those with potassium excretion greater than the median. Higher potassium excretion attenuated the increased cardiovascular risk associated with high sodium excretion (P for interaction=0.007).ConclusionsThese findings suggest that the simultaneous target of low sodium intake (<2 g/day) with high potassium intake (>3.5 g/day) is extremely uncommon. Combined moderate sodium intake (3-5 g/day) with high potassium intake is associated with the lowest risk of mortality and cardiovascular events.

Inhibition of aldosterone-induced antinatriuresis and kaliuresis by actinomycin D

1984 ◽  
Vol 246 (2) ◽  
pp. F201-F204 ◽  
Author(s):  
J. D. Horisberger ◽  
J. Diezi
Keyword(s):  
Urinary Excretion ◽  
Intravenous Infusion ◽  
Sodium Excretion ◽  
Actinomycin D ◽  
Potassium Concentration ◽  
Plasma Potassium ◽  
Potassium Excretion ◽  
Short Term ◽  
Sodium And Potassium ◽  
Term Response

The effects of actinomycin D on short-term response to aldosterone on sodium and potassium urinary excretion were investigated in adrenalectomized glucocorticoid-substituted anesthetized rats. Aldosterone alone (1 microgram/kg followed by sustained intravenous infusion of 1 microgram X kg-1 X h-1) entailed a simultaneous antinatriuretic and kaliuretic effect after a latent period of 30-60 min. Actinomycin D (300 micrograms/kg) administered intravenously 30 min before aldosterone inhibited both the aldosterone-induced kaliuresis and antinatriuresis and the concomitant changes in plasma potassium concentration. The administration of actinomycin D alone enhanced sodium excretion in the first hour and then induced kaliuresis. These results favor the hypothesis that mineralocorticoid effects of aldosterone on sodium and potassium excretion are closely linked and may be dependent on the same mechanisms.

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