scholarly journals Sex Differences in the Impact of the Mediterranean Diet on LDL Particle Size Distribution and Oxidation

Nutrients ◽  
2015 ◽  
Vol 7 (5) ◽  
pp. 3705-3723 ◽  
Author(s):  
Alexandra Bédard ◽  
Louise Corneau ◽  
Benoît Lamarche ◽  
Sylvie Dodin ◽  
Simone Lemieux
Keyword(s):  
Particle Size ◽  
Sex Differences ◽  
Particle Size Distribution ◽  
Size Distribution ◽  
Mediterranean Diet ◽  
Ldl Particle Size ◽  
The Mediterranean ◽  
The Impact

scholarly journals Sex-Related Differences in the Effects of the Mediterranean Diet on Glucose and Insulin Homeostasis

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Alexandra Bédard ◽  
Louise Corneau ◽  
Benoît Lamarche ◽  
Sylvie Dodin ◽  
Simone Lemieux
Keyword(s):  
Sex Differences ◽  
Insulin Sensitivity ◽  
Mediterranean Diet ◽  
Sex Difference ◽  
Premenopausal Women ◽  
Nonesterified Fatty Acids ◽  
Time Interaction ◽  
Insulin Homeostasis ◽  
The Mediterranean ◽  
The Impact

Objective. To document sex differences in the impact of the Mediterranean diet (MedDiet) on glucose/insulin homeostasis and to verify whether these sex-related effects were associated with changes in nonesterified fatty acids (NEFA).Methods. All foods were provided to 38 men and 32 premenopausal women (24–53 y) during 4 weeks. Variables were measured during a 180 min OGTT before and after the MedDiet.Results. A sex-by-time interaction for plasma insulin iAUC was found (men: −17.8%,P=0.02; women: +9.4%,P=0.63;Pfor sex-by-time interaction = 0.005). A sex-by-time interaction was also observed for insulin sensitivity (Cederholm index,P=0.03), for which only men experienced improvements (men: +8.1%,P=0.047; women: −5.9%,P=0.94). No sex difference was observed for glucose and C-peptide responses. Trends toward a decrease in NEFA AUC (P=0.06) and an increase in NEFA suppression rate (P=0.06) were noted, with no sex difference. Changes in NEFA were not associated with change in insulin sensitivity.Conclusions. Results suggest that the more favorable changes in glucose/insulin homeostasis observed in men compared to women in response to the MedDiet are not explained by sex differences in NEFA response. This clinical trial is registered with clinicaltrials.govNCT01293344.

scholarly journals Green Preparation, Spheroidal, and Superior Property of Nano-1,3,5,7-Tetranittro-1,3,5,7-Tetrazocane

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xinlei Jia ◽  
Jingyu Wang ◽  
Conghua Hou ◽  
Yingxin Tan
Keyword(s):  
Activation Energy ◽  
Particle Size ◽  
Fractal Dimension ◽  
Particle Size Distribution ◽  
Size Distribution ◽  
Fractal Theory ◽  
Crystal Form ◽  
Decomposition Temperature ◽  
Scanning Calorimetry ◽  
The Impact

Herein, a green process for preparing nano-HMX, mechanical demulsification shearing (MDS) technology, was developed. Nano-HMX was successfully fabricated via MDS technology without using any chemical reagents, and the fabrication mechanism was proposed. Based on the “fractal theory,” the optimal shearing time for mechanical emulsification was deduced by calculating the fractal dimension of the particle size distribution. The as-prepared nano-HMX was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and differential scanning calorimetry (DSC). And the impact sensitivities of HMX particles were contrastively investigated. The raw HMX had a lower fractal dimension of 1.9273. The ideal shearing time was 7 h. The resultant nano-HMX possessed a particle size distribution ranging from 203.3 nm to 509.1 nm as compared to raw HMX. Nano-HMX particles were dense spherical, maintaining β-HMX crystal form. In addition, they had much lower impact sensitivity. However, the apparent activation energy as well as thermal decomposition temperature of nano-HMX particles was decreased, attributing to the reduced probability for hotspot generation. Especially when the shearing time was 7 h, the activation energy was markedly decreased.

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