scholarly journals Obesity and Cardiometabolic Risk Factors: From Childhood to Adulthood

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4176
Author(s):  
Dorota Drozdz ◽  
Julio Alvarez-Pitti ◽  
Małgorzata Wójcik ◽  
Claudio Borghi ◽  
Rosita Gabbianelli ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Preventive Strategies ◽  
Prevention Strategies ◽  
Perinatal Factors ◽  
The Metabolic Syndrome

Obesity has become a major epidemic in the 21st century. It increases the risk of dyslipidemia, hypertension, and type 2 diabetes, which are known cardiometabolic risk factors and components of the metabolic syndrome. Although overt cardiovascular (CV) diseases such as stroke or myocardial infarction are the domain of adulthood, it is evident that the CV continuum begins very early in life. Recognition of risk factors and early stages of CV damage, at a time when these processes are still reversible, and the development of prevention strategies are major pillars in reducing CV morbidity and mortality in the general population. In this review, we will discuss the role of well-known but also novel risk factors linking obesity and increased CV risk from prenatal age to adulthood, including the role of perinatal factors, diet, nutrigenomics, and nutri-epigenetics, hyperuricemia, dyslipidemia, hypertension, and cardiorespiratory fitness. The importance of ‘tracking’ of these risk factors on adult CV health is highlighted and the economic impact of childhood obesity as well as preventive strategies are discussed.

scholarly journals Association of intraocular pressure with the metabolic syndrome and novel cardiometabolic risk factors

Eye ◽  
2009 ◽  
Vol 24 (6) ◽  
pp. 1037-1043 ◽  
Author(s):  
Y C Chang ◽  
J-W Lin ◽  
L C Wang ◽  
H M Chen ◽  
J J Hwang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Intraocular Pressure ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
The Metabolic Syndrome

scholarly journals Functional high-intensity exercise training ameliorates insulin resistance and cardiometabolic risk factors in type 2 diabetes

2018 ◽  
Vol 103 (7) ◽  
pp. 985-994 ◽  
Author(s):  
Ciarán E. Fealy ◽  
Stephan Nieuwoudt ◽  
Julie A. Foucher ◽  
Amanda R. Scelsi ◽  
Steven K. Malin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Exercise Training ◽  
High Intensity ◽  
Cardiometabolic Risk ◽  
High Intensity Exercise ◽  
Cardiometabolic Risk Factors

Abstract MP67: Lactation Duration and Subsequent Intima Media Thickness in Women During Midlife Controlling for Pre-pregnancy Cardiometabolic Risk Factors: The CARDIA Study

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Erica P Gunderson ◽  
Cora E. Lewis ◽  
Xian Ning ◽  
Mark Pletcher ◽  
David Jacobs ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Weight Gain ◽  
Cardiometabolic Risk ◽  
Intima Media Thickness ◽  
Cardiometabolic Risk Factors ◽  
Inverse Association ◽  
Media Thickness ◽  
The Metabolic Syndrome ◽  
Lactation Duration

Background: Greater lactation duration has been associated with lower incidence of the metabolic syndrome, and self-reported type 2 diabetes and heart disease in women later in life. Two retrospective studies reported higher carotid artery intima-media thickness among parous women who never or inconsistently breastfed, but no clear association with duration. However, lactation history was recalled many years later and heart disease risk factors were not measured before pregnancy. We hypothesized that lactation duration has a graded inverse association with subclinical atherosclerosis in women during mid-life independent of pre-pregnancy cardiometabolic risk factors. Methods: We examined 846 women (46% Black), aged 18-30 years at enrollment in 1985-1986 (baseline) in the biracial Coronary Artery Risk Development in Young Adults (CARDIA) study. Women included delivered 1 or more live births from 1986-2005, had no history of heart disease or diabetes before pregnancies, and had maximum common carotid intima media thickness (ccIMT, mm) measured in 2005-2006 at ages 38-50 years. Lactation duration was recalled within 1 to 4 years of delivery. We categorized women into four lactation groups according to cumulative duration for all post-baseline births; 0-<1 month (n=262), 1-<6 months (n=210), 6-10 months (n=169) and >10 months (n=205). Multiple linear regression models estimated mean ccIMT (95% CI) among lactation categories adjusted for pre-pregnancy cardiometabolic risk factors [BMI, systolic blood pressure (SBP), HDL-C, HOMA-IR], parity, socio-demographics (age, race, education), and smoking. We also assessed weight gain and change in SBP as mediators of the lactation and ccIMT association. Results: Increasing lactation duration showed a graded inverse association with mean ccIMT; differences between >10 months vs. 0<1 month groups ranged from -0.062 from the unadjusted model (p<0.001) and -0.029 from adjusted models (p=0.046) that included pre-pregnancy risk factors and other covariates. Weight gain and SBP change during the 20-year follow up slightly attenuated (~10%) the ccIMT-association with increased lactation duration. Conclusions: Greater lactation duration is associated with lower mean ccIMT independent of cardiometabolic risk factors measured before pregnancy, parity, socio-demographics and smoking. Lactation may have lasting favorable effects on cardiometabolic risk factors for heart disease.

80-OR: Treatment with Once-Weekly Semaglutide 2.4 mg Improves Cardiometabolic Risk Factors in Adults with Overweight/Obesity and Type 2 Diabetes: STEP 2 Post-hoc Analysis

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 80-OR
Author(s):  
ROBERT F. KUSHNER ◽  
MELANIE J. DAVIES ◽  
JOHN DEANFIELD ◽  
W. TIMOTHY GARVEY ◽  
OLE JEPPESEN ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Post Hoc Analysis ◽  
Post Hoc

Baru Nut Intake and Resistance Training Practice Have Potential to Reduce the Cardiometabolic Risk Factors in Type 2 Diabetes

2021 ◽  
Vol 17 ◽  
Author(s):  
John Sebastião Cardoso da Silva ◽  
Maria Sebastiana Silva ◽  
Maria Margareth Veloso Naves
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Resistance Training ◽  
Cardiometabolic Risk ◽  
Nutritional Composition ◽  
Cardiometabolic Risk Factors ◽  
Cardiometabolic Health

Background: Type 2 diabetes mellitus (T2DM) is a disease associated with several cardiometabolic risk factors (CMRF). There is strong evidence about the benefits of oilseeds intake and the practice of resistance training (RT) in the prevention and treatment of T2DM and its associated CMRF. However, no study has evaluated the combination of these interventions yet. Baru nut, an oilseed native to the Brazilian Cerrado, stands out among oilseeds due to its healthy nutritional composition, which have the potential to reduce CMRF in T2DM. RT, in turn, provides positive changes in the composition and metabolism of muscle cells, which contributes to improving cardiometabolic health. Objective: This review aimed to summarize the effects and mechanisms related to the intake of baru nut and the practice of RT in reducing CMRF in T2DM. Method: Literature research was performed using the keywords "type 2 diabetes mellitus", "Dipteryx alata Vog", "nuts", "physical exercise" and "resistance training", isolated or associated, in Web of Science and Pubmed databases. Results: Baru nut is an oilseed with high density of nutrients and bioactive compounds with antioxidant and antihypercholesterolemic properties, and the RT is associated with beneficial effects on CMRF in T2DM individuals. Thus, the consumption of baru nut and the RT have potential to improve the insulin sensitivity, glycemic control, body composition, and serum lipid profile. Conclusion: The baru nut consumption and the RT have potential to reduce the cardiometabolic risk factors in T2DM. Both interventions are innovative and promising approaches to preserve the health of T2DM individuals.

scholarly journals Interleukin-15 and irisin serum concentrations are not related to cardiometabolic risk factors in patients with type 2 diabetes from Korea and Germany

2019 ◽  
Vol 57 (3) ◽  
pp. 381-384 ◽  
Author(s):  
Kyung Mook Choi ◽  
Soon Young Hwang ◽  
Kyungdo Han ◽  
Hye Soo Chung ◽  
Nam Hoon Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Serum Concentrations ◽  
Interleukin 15
Sign in / Sign up

Export Citation Format

Share Document