scholarly journals Influence of Vitamin D Supplementation on Mental Health in Diabetic Patients: A Systematic Review

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3678
Author(s):  
Dominika Guzek ◽  
Aleksandra Kołota ◽  
Katarzyna Lachowicz ◽  
Dominika Skolmowska ◽  
Małgorzata Stachoń ◽  
...  

Diabetes is associated with a number of mental health consequences, including enhanced risk of depression and anxiety, as well as decreased quality of life, and vitamin D deficiency is considered to be one of the factors that influence these outcomes in diabetic patients. The aim of the present study was to conduct a systematic review of the literature presenting the data regarding the influence of vitamin D supplementation on mental health in diabetic adults. This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (Registration number CRD42020155779). A systematic search of the PubMed and Web of Science databases was performed, and the intervention studies published until September 2021 were included in the review. The human studies were included if an adult sample of diabetic individuals received vitamin D supplementation during the intervention and its effect on any mental health aspect was assessed, but studies presenting the influence of combined supplementation of multiple nutrients were excluded. After removing duplicate records, a total of 8,514 publications were screened and assessed independently by two researchers, based on their title, abstract, and full text. Finally, six studies were included in the current systematic review, and the risk of bias was evaluated using the Newcastle–Ottawa Scale (NOS). The included studies analyzed the influence of a specific dose of vitamin D, or different doses of vitamin D, or compared the results of supplementation with a specific dose of vitamin D against the placebo group. The supplementation was performed for at least 12 weeks. The mental health outcomes analyzed in these studies included health-related quality of life, depression, anxiety, stress, and general mental health status of adult diabetic patients. The results of the majority of the studies confirmed the positive influence of vitamin D supplementation on the mental health of diabetic individuals. Those studies that analyzed the influence of vitamin D supplementation on depression and anxiety established the beneficial effect of the vitamin. In some studies, the influence of vitamin D supplementation on the health-related quality of life was not considered unless combined with mindfulness training. However, it must be emphasized that different dosage regimens and intervention periods were followed in the reviewed studies, and only a small number of studies were randomized against placebo, which should be considered as a limitation of the present study. The findings of the conducted systematic review demonstrated the positive influence of vitamin D supplementation on the mental health of diabetic patients, which was proved for anxiety and depression, but in the case of health-related quality of life, the positive effect was observed only when the intervention included mindfulness training. These outcomes suggest that supplementation should be recommended to improve the vitamin D status and the mental health of patients in this group.

2018 ◽  
Vol 50 (5S) ◽  
pp. 729-730 ◽  
Author(s):  
Kelly A. Dougherty ◽  
Chiara Bertolaso ◽  
Joan I. Schall ◽  
Kim Smith-Whitley ◽  
Virginia A. Stallings

Author(s):  
Nicolaas Martens ◽  
Marianne Destoop ◽  
Geert Dom

It is well established that persons with a severe mental illness (SMI) have a greater risk of physical comorbid conditions and premature mortality. Most studies in the field of community mental health care (CMHC) have only focused on improving cardiovascular health in people with a SMI using lifestyle approaches. Studies using organizational modifications are rather scarce. This systematic review aimed to synthesize and describe possible organizational strategies to improve physical health for persons with a SMI in CMHC. The primary outcome was Health-related Quality of Life (HR-QOL). Results suggested modest effects on quality of life and were inconsistent throughout all the included studies. Despite these findings, it appears that a more integrated approach had a positive effect on health outcomes, patient satisfaction and HR-QOL. The complexity of the processes involved in community care delivery makes it difficult to compare different models and organizational approaches. Mental health nurses were identified as possible key professionals in care organization, but no clear description of their role was found. This review could provide new insights into contributing factors for integrated care. Future research targeting the identification of the nurses’ role and facilitating factors in integrated care, in order to improve treatment and follow-up of somatic comorbidities, is recommended.


2015 ◽  
Vol 4 (3) ◽  
pp. 13-16 ◽  
Author(s):  
R K Mehta ◽  
S Subedi ◽  
S Bohora

Globally, diabetes is ranked as the 4th leading cause of death in terms of disease and places a huge strain on public health funding. Quality of life (QOL) is an important and understudied topic in the diabetes. Most studies reports that quality of life among people with diabetes is worse than QOL in general population. Thus, this study is aimed to assess health related quality of life of diabetic patients. We conducted a hospital- based non experimental prospective study. Total 50 diabetic patients were enrolled in this study by using purposive sampling technique. Short-Form 36 questionnaire was used to assess the QOL of diabetic patients. Among 50 respondents, 27 were female and 23 were male. In physical health, 56% respondents had obtained score above 50, 2% respondents had obtained score 50 and 42% respondents had obtained score below 50.Similarly, in mental health, 56% respondents had obtained score above 50 and 44% respondents had obtained score below50. This result indicates that majority of respondents (56%) had better QOL. It concludes that majority (56%) of respondents had better QOL in both physical and mental health and in physical health 2% had average QOL and 42% had poor QOL and in mental health 44% had poor QOL. So, the family, physician, nurses and policy makers can use this finding to identify and implement appropriate interventions for better management and ultimately improving QOL of diabetic patients.DOI: http://dx.doi.org/10.3126/jcmc.v4i3.11933Journal of Chitwan Medical College 2014; 4(3): 13-16 


2016 ◽  
Vol 20 (10) ◽  
pp. 1844-1850 ◽  
Author(s):  
Foong Ming Moy ◽  
Victor CW Hoe ◽  
Noran Naqiah Hairi ◽  
Shireene Ratna Vethakkan ◽  
Awang Bulgiba

AbstractObjectiveTo determine the association of vitamin D status with depression and health-related quality of life among women.DesignThis was a cross-sectional study conducted among women in Kuala Lumpur, Malaysia. Sociodemographic characteristics, physical activity status, perceived depression and health-related quality of life were assessed via a self-administered questionnaire. Fasting blood samples were taken for the analysis of 25-hydroxyvitamin D, parathyroid hormone, fasting blood glucose and full lipid profile. Complex samples multiple logistic regression analysis was performed.SettingPublic secondary schools in Kuala Lumpur, Malaysia.SubjectsSeven hundred and seventy female teachers were included.ResultsThe mean age of participants was 41·15 (95 % CI 40·51, 41·78) years and the majority were ethnic Malays. Over 70 % of them had vitamin D deficiency (<20 ng/ml or <50 nmol/l) and two-thirds were at risk for depression. In the multivariate analysis, ethnic Malays (adjusted OR (aOR)=14·72; 95 % CI 2·12, 102·21) and Indians (aOR=14·02; 95 % CI 2·27, 86·59), those at risk for depression (aOR=1·88, 95 % CI 1·27, 2·79) and those with higher parathyroid hormone level (aOR=1·13; 95 % CI 1·01, 1·26) were associated with vitamin D deficiency, while vitamin D deficiency was negatively associated with mental health-related quality of life (Mental Component Summary) scores (aOR=0·98; 95 % CI 0·97, 0·99).ConclusionsVitamin D deficiency is significantly associated with depression and mental health-related quality of life among women in Kuala Lumpur, Malaysia.


2020 ◽  
Vol 103 (11) ◽  
pp. 1185-1193

Background: The systemic lupus erythematosus (SLE) patients oftentimes suffer from both physical and psychosocial challenges that may lead to low health-related quality of life (HRQoL). However, limited research has been done in this area. Objective: To examined mental health status and HRQoL among SLE patients in Thailand. Materials and Methods: The present study was a cross-sectional study conducted at the rheumatology clinic of four major hospitals in Thailand. The paper-based questionnaire consisted of demographic, health history such as depression, anxiety, stress Scale (DASS-21), and the Rosenberg self-esteem scale (RSE), and the disease-specific Lupus Quality of Life scale (LupusQoL). Depending on the variable’s level of measurement such as categorical or continuous, Spearman’s Rho or Pearson’s product moment correlation coefficients were used to explore the relationships among the variables. Hierarchical multiple regression was used to identify the predictors of LupusQoL. Results: Among the 387 participants, many might have experienced depression, anxiety, and stress (30%, 51%, and 29%, respectively). Self-esteem among the participants was good (31.8 out of 40). All eight domains of LupusQoL were affected with intimate relationship domain being impacted the most. The overall LupusQoL was significantly associated with the number of prescribed medications (r=–0.23), depression (r=–0.70), anxiety (r=–0.58), stress (r=–0.67), and self-esteem (r=0.59), p<0.001. Significant predictors of the overall LupusQoL were mental health status (depression, anxiety, and stress) and self-esteem, F (3, 81)=43.10, p<0.001, adjusted R²=0.60. Conclusion: SLE patients should be holistically assessed in both physical and psychological aspects. In addition to proper medical treatments, healthcare providers should use a multidisciplinary team approach to resolve the patients’ psychosocial issues, which in turn, may increase the patients’ quality of life. Self-care education may be necessary to help the patients manage the condition and decrease the number of medications. Keywords: Mental health, Quality of life, SLE, Thailand


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