scholarly journals Manganese Encephalopathy Caused by Homemade Methcathinone (Ephedrone) Prevalence in Poland

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3496
Author(s):  
Bogusław Habrat ◽  
Andrzej Silczuk ◽  
Anna Klimkiewicz

Manganese encephalopathy is a known disorder in occupational medicine. A serious phenomenon has been the emergence of manganese encephalopathy in intravenous users of homemade methcathinone (ephedrone). A short survey was developed for clinical environments dealing with people who use psychoactive substances. The data were obtained from 72 rehabilitation therapy centers. Surveys carried out in about a third of Polish centers dealing with providing medical assistance to people addicted to substances other than alcohol and tobacco have shown that over 4% of people treated there had symptoms of manganese encephalopathy, of which more than half are people in whom the probability of a clinical diagnosis of this disorder is significant. It has been shown that knowledge of manganese encephalopathy is none or minimal in more than 70% of the surveyed institutions. An urgent need for personnel training in this field was pointed out. Attention was paid to the importance of disseminating good review articles on new and dynamically developing problem phenomena.

2019 ◽  
Vol 6 (8) ◽  
pp. 3026
Author(s):  
Vinayak Rengan ◽  
Vinodh Duraisami ◽  
Chetna Ravindra ◽  
Karthik Muralidharan

A 48 years old man presented to the surgical OPD with a history of multiple painless swellings on his scrotum for 20 years. He had avoided all sexual relations with his wife due to potential embarrassment. A clinical diagnosis of scrotal epidermoid cysts was made. Both testes were normal on ultrasound. Upon surgery, the scrotal skin was thoroughly excised, and primary closure of skin was done. Postoperative period was uneventful. The patient engaged in intercourse with his partner two weeks after surgery. The man and his partner were referred to the psychiatry unit for appropriate counselling. Scrotal epidermoid cysts cause significant psychological handicap. In Asian countries, the taboo of seeking medical assistance for genital conditions still exists. The treatment of scrotal epidermoid cysts requires a team of surgeons, psychologists, and psychiatrists.


Author(s):  
Charles Rodrigues

Abstract.Previous literature considers the existence of intellectual differences in children with ADHD when the parents are addicts to psychoactive substances. The aim of this work was to verify this intellectual difference between children with ADHD, with influence or not, of cocaine use by the father, during ovulation and fertilization of the mother. The sample was composed by 45 children, all male, with clinical diagnosis ADHD, accompanied on 12 educational institutions, 9 publics and 3 private, of the District of Lisbon. The sample was divided into two groups and subjected to quantitative assessment by applying the WISC III. The results present statistically significant differences, whereby we may conclude that there more intellectual’s difficulties in children with ADHD, when the father had cocaine use during ovulation periods and fertilization of the mother.Keywords: ADHD, cocaine, intelligence, ovulation, fertilization.Resumo.Literatura prévia considera a existência de diferenças intelectuais em crianças com PHDA quando o progenitor ou progenitores são adictos a substâncias psicoativas. O objectivo deste trabalho foi verificar esta diferença intelectual entre crianças com PHDA, com influência ou não, do consumo de cocaína por parte do progenitor, nos períodos de ovulação e fecundação da progenitora. A amostra foi composta por 45 crianças, todas do sexo masculino, com diagnóstico clínico PHDA, acompanhadas em 12 instituições escolares, 9 públicas e 3 privadas do Distrito de Lisboa. A amostra foi dividida em dois grupos e submetida a uma avaliação quantitativa efectuada através da aplicação da WISC III. Os resultados apresentam diferenças estatisticamente significativas, das quais se pode concluir que existem maiores dificuldades intelectuais em crianças com PHDA, quando o progenitor tenha efectuado consumo de cocaína nos períodos de ovulação e fecundação da progenitora.Palavras-chave: PHDA, cocaína, inteligência, ovulação, fecundação


1981 ◽  
Vol 94 ◽  
pp. 111-125
Author(s):  
Edward B. Fomalont

The understanding of the nature of strong radio emission associated with galaxies and quasars has significantly increased in the last five years. A large contribution to this increase has been obtained from the arcsec and milli-arcsec mapping of radio sources which show remarkable features. Because of the recent, extremely good review articles concerning extended extragalactic radio sources (Miley 1980 and Willis 1978), I shall emphasize some new, mostly unpublished works, stemming from VLA observations. This is not to slight European experimental and theoretical work which have led in the formulation of our current thinking, but to try to bridge the inevitable communication gap caused by the Atlantic Ocean and ever higher airfares.


Author(s):  
Tong Wensheng ◽  
Lu Lianhuang ◽  
Zhang Zhijun

This is a combined study of two diffirent branches, photogrammetry and morphology of blood cells. The three dimensional quantitative analysis of erythrocytes using SEMP technique, electron computation technique and photogrammetry theory has made it possible to push the study of mophology of blood cells from LM, TEM, SEM to a higher stage, that of SEM P. A new path has been broken for deeply study of morphology of blood cells.In medical view, the abnormality of the quality and quantity of erythrocytes is one of the important changes of blood disease. It shows the abnormal blood—making function of the human body. Therefore, the study of the change of shape on erythrocytes is the indispensable and important basis of reference in the clinical diagnosis and research of blood disease.The erythrocytes of one normal person, three PNH Patients and one AA patient were used in this experiment. This research determines the following items: Height;Length of two axes (long and short), ratio; Crevice in depth and width of cell membrane; Circumference of erythrocytes; Isoline map of erythrocytes; Section map of erythrocytes.


VASA ◽  
2004 ◽  
Vol 33 (4) ◽  
pp. 247-251 ◽  
Author(s):  
Zeller ◽  
Koch ◽  
Frank ◽  
Bürgelin ◽  
Schwarzwälder ◽  
...  

Diagnosis of non-specific aorto-arteritis (NSAA, Takaysu's arteritis) is typically based on clinical and investigational parameters. We report here about two patients with clinically suspected diagnosis of a Takayasu's arteritis already under anti-inflammatory therapy in whom percutaneous transluminal atherectomy of subclavian and axillary artery stenoses was performed to relief the patients from symptoms – intermittent dyspraxia of the arms – and to verify the clinical diagnosis by histology. In the first case aorto-arteritis could be histologically confirmed through the analysis of plaque material including media structures excised from the subclavian and axillary arteries using a new device for atherectomy. The biopsy showed diffuse inflammation and granulomatous lesions with giant cells typically for Takayasu's disease. In the second patient, biopsy showed no acute or chronic inflammatory signs but only atherosclerotic lesions. Percutaneous transluminal atherectomy is therefore not only an interventional but also a diagnostic tool and should be used in every case of interventional therapy of suspected aorto-arteritis to make the clinical diagnosis and as a major consequence the initiation of an aggressive anti-inflammatory medical therapy more reliable.


VASA ◽  
2015 ◽  
Vol 44 (2) ◽  
pp. 122-128 ◽  
Author(s):  
Mandy Becker ◽  
Tom Schilling ◽  
Olga von Beckerath ◽  
Knut Kröger

Background: To clarify the clinical use of sonography for differentiation of edema we tried to answer the question whether a group of doctors can differentiate lymphedema from cardiac, hepatic or venous edema just by analysing sonographic images of the edema. Patients and methods: 38 (70 ± 12 years, 22 (58 %) females) patients with lower limb edema were recruited according the clinical diagnosis: 10 (26 %) lymphedema, 16 (42 %) heart insufficiency, 6 (16 %) venous disorders, 6 (16 %) chronic hepatic disease. Edema was depicted sonographically at the most affected leg in a standardised way at distal and proximal calf. 38 sets of images were anonymised and send to 5 experienced doctors. They were asked whether they can see criteria for lymphedema: 1. anechoic gaps, 2. horizontal gaps and 3. echoic rims. Results: Accepting an edema as lymphedema if only one doctor sees at least one of the three criteria for lymphatic edema on each single image all edema would be classified as lymphatic. Accepting lymphedema only if all doctors see at least one of the three criteria on the distal image of the same patient 80 % of the patients supposed to have lymphedema are classified as such, but also the majority of cardiac, venous and hepatic edema. Accepting lymphedema only if all doctors see all three criteria on the distal image of the same patients no edema would be classified as lymphatic. In addition we separated patients by Stemmers’ sign in those with positive and negative sign. The interpretation of the images was not different between both groups. Conclusions: Our analysis shows that it is not possible to differentiate lymphedema from other lower limb edema sonographically.


2019 ◽  
Vol 30 (3) ◽  
pp. 157-168
Author(s):  
Helmut Hildebrandt ◽  
Jana Schill ◽  
Jana Bördgen ◽  
Andreas Kastrup ◽  
Paul Eling

Abstract. This article explores the possibility of differentiating between patients suffering from Alzheimer’s disease (AD) and patients with other kinds of dementia by focusing on false alarms (FAs) on a picture recognition task (PRT). In Study 1, we compared AD and non-AD patients on the PRT and found that FAs discriminate well between these groups. Study 2 served to improve the discriminatory power of the FA score on the picture recognition task by adding associated pairs. Here, too, the FA score differentiated well between AD and non-AD patients, though the discriminatory power did not improve. The findings suggest that AD patients show a liberal response bias. Taken together, these studies suggest that FAs in picture recognition are of major importance for the clinical diagnosis of AD.


2017 ◽  
Vol 225 (3) ◽  
pp. 189-199 ◽  
Author(s):  
Tina B. Lonsdorf ◽  
Jan Richter

Abstract. As the criticism of the definition of the phenotype (i.e., clinical diagnosis) represents the major focus of the Research Domain Criteria (RDoC) initiative, it is somewhat surprising that discussions have not yet focused more on specific conceptual and procedural considerations of the suggested RDoC constructs, sub-constructs, and associated paradigms. We argue that we need more precise thinking as well as a conceptual and methodological discussion of RDoC domains and constructs, their interrelationships as well as their experimental operationalization and nomenclature. The present work is intended to start such a debate using fear conditioning as an example. Thereby, we aim to provide thought-provoking impulses on the role of fear conditioning in the age of RDoC as well as conceptual and methodological considerations and suggestions to guide RDoC-based fear conditioning research in the future.


1963 ◽  
Vol 8 (2) ◽  
pp. 43-44
Author(s):  
Fillmore H. Sanford
Keyword(s):  

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