scholarly journals Human Microbiota Network: Unveiling Potential Crosstalk between the Different Microbiota Ecosystems and Their Role in Health and Disease

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2905
Author(s):  
Jose E. Martínez ◽  
Augusto Vargas ◽  
Tania Pérez-Sánchez ◽  
Ignacio J. Encío ◽  
Miriam Cabello-Olmo ◽  
...  

The human body is host to a large number of microorganisms which conform the human microbiota, that is known to play an important role in health and disease. Although most of the microorganisms that coexist with us are located in the gut, microbial cells present in other locations (like skin, respiratory tract, genitourinary tract, and the vaginal zone in women) also play a significant role regulating host health. The fact that there are different kinds of microbiota in different body areas does not mean they are independent. It is plausible that connection exist, and different studies have shown that the microbiota present in different zones of the human body has the capability of communicating through secondary metabolites. In this sense, dysbiosis in one body compartment may negatively affect distal areas and contribute to the development of diseases. Accordingly, it could be hypothesized that the whole set of microbial cells that inhabit the human body form a system, and the dialogue between the different host microbiotas may be a contributing factor for the susceptibility to developing diseased states. For this reason, the present review aims to integrate the available literature on the relationship between the different human microbiotas and understand how changes in the microbiota in one body region can influence other microbiota communities in a bidirectional process. The findings suggest that the different microbiotas may act in a coordinated way to decisively influence human well-being. This new integrative paradigm opens new insights in the microbiota field of research and its relationship with human health that should be taken into account in future studies.

2021 ◽  
Vol 9 (4) ◽  
pp. 77-98
Author(s):  
Noorlila Ahmad ◽  
Siti Fatimah Abd Rahman

The influence of the natural environment on emotional well-being has been highlighted at the peak of the Covid 19 pandemic that saw most countries impose prolonged total lockdowns and movement restrictions on their citizens. While researchers have recently emphasized the need to focus not only on students’ academic achievement but also on their inner needs, which include their emotional well-being, studies have found nature connectedness has a positive effect on emotional well-being and physical health. Many studies on nature and well-being have focused on physiological and psychological experimental research to examine before and after exposure to nature. However, there is still a need for further investigation how emotional connection between nature environments in the aspect of restorativeness and spiritual values improve mental health.  This paper systematically reviewed previous studies about the relationship between exposure to the natural environment and well-being focusing on key variables, underpinning theories, methodological processes and samples. As a result of the review, a conceptual framework is proposed for future studies on relationship between exposure to the natural environment and well-being. We hope that the proposed framework will be empirically tested in future studies.


2020 ◽  
Vol 2 (2) ◽  
pp. 185-196
Author(s):  
Yadira Rivera Espinoza

A vast number of microorganisms inhabit the human body and coexist peacefully with their hosts, under specific conditions. The complex ecosystem of microbial communities found in the intestine fulfills numerous metabolic, physiological, and protective functions of the human body. Recent studies show that an imbalance in these communities (dysbiosis) maintains a close relationship with the health of the host. The change in eating habits, lifestyle, and different compounds of exogenous origin are some of the main factors causing that alteration, which represent new challenges for medical practice. Therefore, the objective of this document is to provide information about the intestinal microbiota concept, the factors altering it, some of the diseases associated with dysbiosis, and the evidence of some foods that may induce the modulation of the intestinal microbiota. Knowing the relationship between food, microbiota, and health is relevant to have more elements in the treatment of diseases in modern society.


Pathogens ◽  
2019 ◽  
Vol 8 (2) ◽  
pp. 70 ◽  
Author(s):  
Wibke Krüger ◽  
Sarah Vielreicher ◽  
Mario Kapitan ◽  
Ilse Jacobsen ◽  
Maria Niemiec

Fungi and bacteria encounter each other in various niches of the human body. There, they interact directly with one another or indirectly via the host response. In both cases, interactions can affect host health and disease. In the present review, we summarized current knowledge on fungal-bacterial interactions during their commensal and pathogenic lifestyle. We focus on distinct mucosal niches: the oral cavity, lung, gut, and vagina. In addition, we describe interactions during bloodstream and wound infections and the possible consequences for the human host.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S660-S660
Author(s):  
Anna Swall ◽  
Christine Williams ◽  
Lena Marmstål Hammar

Abstract Background: Living with dementia involves both illness and health and involves self-care and care by others. As most persons with dementia are living in their ordinary housing, dementia affects not only the person with the disease, but also the life of the family, commonly the partner. Research show that spouse carers feel like they are losing their partners due to an inability to share thoughts, feelings and experiences as a couple. Aim: The aim of the study was to describe spouse’s experience of their togetherness when one spouse has dementia. Method: The sample consisted of eighteen recorded conversations between 15 persons with dementia and their spouses. The filmed conversations were transcribed verbatim and then analyzed using qualitative content analysis. Findings: One overarching theme arose from the data “Dementia preserved and challenged the value of “us”. Being a couple trying to preserve a sense of togetherness and have the relationship they wished for could be seen as a challenge when one spouse was living with dementia. Conclusion: Based on our results, we suggest that practitioners should help couples to reinforce or strengthen their bonds as a couple to maintain well-being. Future studies should examine couplehood under differing conditions such as long versus short term relationships. Prior relationship quality may also be a factor influencing the sense of couplehood following a serious health challenge such as dementia.


2020 ◽  
Vol 10 (86) ◽  
Author(s):  
Yeva-Anna Demchenko ◽  
◽  
Oksana Lan ◽  
Petro Luno ◽  
◽  
...  

The article clarifies the problem of redistribution of energy in the human body, in its etheric body. Seven main energy channels (chakras) are described, which are located on the line of the human rod, their location, spectrum, color, sound, anatomical and physical image. The characteristics of each chakra are given, where the color of the chakra is indicated, which indicates certain fluctuations of energy in the human body with different frequency and amplitude and the correspondence of each of the chakras to a special lotus flower with different number of petals. There is a regularity of lack of energy in a chakra, and this is reflected in the physical body. Psychosomatics has also been linked to illness and emotional state. The personal manifestations of the choreographer's creative creativity, connected with artistic and figurative associations with the color of human energy chakras and the creation of a creative product using the appropriate yoga asanas in the choreographic vocabulary, were studied. The relationship between human energy, behavior and dependence on excess or lack of energy in a particular chakra is analyzed. Find out how human behavior is reflected in a choreographic image. The creation of a plastic-artistic image on the example of energy and color of human chakras is carried out. The peculiarities of creating the dynamics of the image, its character and behavior of the individual are established. The peculiarity of asanas and their connection with well-being and self-expression are analyzed and singled out. The question of researching previously unsolved parts of the general problem arises: personal manifestations of the choreographer's creative work, associated with artistic associations with the color of human energy chakras and creating a creative product using choreographic vocabulary using appropriate yoga asanas. Examples of choreographers using a special range of colors as sources-associations in the process of creating a script for choreographic performances are given; the prospects of research of creativity of the choreographer, his creativity and self-realization are defined.


2021 ◽  
Vol 8 ◽  
Author(s):  
Li Xi ◽  
Xinxi Qin ◽  
Yumin Song ◽  
Jincheng Han ◽  
Zhiqiang Li ◽  
...  

The structure and composition of gut microbiota correlate with the occurrence and development of host health and disease. Diarrhea can cause alterations in gut microbiota in animals, and the changes in the gut microbial structure and composition may affect the development of diarrhea. However, there is a scarcity of information on the effects of diarrhea on gut fungal composition and structure, particularly in Baer's pochard (Aythya baeri). The current study was performed for high-throughput sequencing of the fungal-specific internal transcribed spacer 1 (ITS-1) to detect the differences of gut mycobiota in healthy and diarrheal Baer's pochard. Results showed that the gut mycobiota not only decreased significantly in diversity but also in structure and composition. Statistical analysis between two groups revealed a significant decrease in the abundance of phylum Rozellomycota, Zoopagomycota, Mortierellomycota, and Kickxellomycota in diarrheal Baer's pochard. At the genus levels, fungal relative abundance changed significantly in 95 genera, with 56 fungal genera, such as Wickerhamomyces, Alternaria, Penicillium, Cystofilobasidium, and Filobasidium, increasing significantly in the gut of the diarrheal Baer's pochard. In conclusion, the current study revealed the discrepancy in the gut fungal diversity and community composition between the healthy and diarrheal Baer's pochard, laying the basis for elucidating the relationship between diarrhea and the gut mycobiota in Baer's pochard.


2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Jhanghiz Syahrivar ◽  
Syafira Alyfania Hermawan ◽  
Tamás Gyulavári ◽  
Chairy Chairy

PurposeIn general, Muslims consider Islamic consumption to be a religious obligation. Previous research, however, suggests that various socio-psychological factors may influence Islamic consumption. Failure to comprehend the true motivations for purchasing Islamic products may lead to marketing myopia. This research investigates the less explored motivational factors of religious compensatory consumption, namely religious hypocrisy, religious social control and religious guilt.Design/methodology/approachThis research relied on an online questionnaire. Purposive sampling yielded a total of 238 Muslim respondents. The authors employed PLS-SEM analysis with the ADANCO software to test the hypotheses.FindingsThe results reveal the following: (1) Higher religious hypocrisy leads to higher religious social control. (2) Higher religious hypocrisy leads to higher religious guilt. (3) Higher religious social control leads to higher religious guilt. (4) Higher religious hypocrisy leads to higher religious compensatory consumption. (5) Higher religious social control leads to higher religious compensatory consumption. (6) Religious social control partially mediates the relationship between religious hypocrisy and religious compensatory consumption. (7) Higher religious guilt leads to higher religious compensatory consumption. (8) Religious guilt partially mediates the relationship between religious hypocrisy and religious compensatory consumption.Research limitations/implicationsFirst, religious compensatory consumption in this research is limited to Muslim consumers. Future research may investigate compensatory consumption in different contexts, such as Judaism and Christianity, which have some common religious tenets. Second, compensatory consumption is a complex concept. The authors’ religious compensatory consumption scale only incorporated a few aspects of compensatory consumption. Future studies may retest the authors’ measurement scale for reliability. Lastly, the samples were dominated by the younger generation of Muslims (e.g. generation Z). Future studies may investigate older Muslim generations.Practical implicationsFirst, this research illustrates how religiosity, guilt and social control may contribute to Islamic compensatory consumption. Islamic business practitioners and retailers targeting Muslim consumers can benefit from this research by knowing that Islamic consumption may be driven by socio-psychological factors, such as religious hypocrisy and guilt. As a result, businesses targeting Muslim consumers can develop marketing strategies that incorporate these religious elements while also addressing their socio-psychological issues in order to promote Islamic products. Second, Islamic business practitioners and retailers may consider the social environments in which Muslims are raised. The authors’ findings show that religious social control has direct and indirect effects on Muslims' preferences for Islamic products as a form of compensatory strategy. Islamic business practitioners may design marketing programs that revolve around Muslim families and their Islamic values. It is in line with the previous studies that suggest the connections between religions, local cultures and buying behaviours (Ng et al., 2020; Batra et al., 2021). In some ways, Islamic products can be promoted to improve the well-being and cohesion of family members and Muslim society in general. In this research, the authors argue that businesses' failures to understand the socio-psychological motives of Islamic consumption may lead to marketing myopia.Social implicationsAs previously stated, religion (i.e. Islam) may be a source of well-being and a stable relationship among Muslims. Nevertheless, it may also become a source of negative emotions, such as guilt, because of one's inability to fulfil religious values, ideals or standards. According to the authors’ findings, Islamic products can be used to compensate for a perceived lack of religiosity. At the same time, these products may improve Muslims' well-being. The creations of products and services that revolve around Islamic values are expected to improve Muslims' economic conditions and strengthen their faith and love toward Islam in the globalized world. Moreover, Muslims, both as majority and minority groups, face increasing social pressures. On one hand there is the (in-group) pressure to uphold Islamic values and on the other hand there is the (out-group) pressure to preserve the local values and cultures. Indeed, living in the globalized world may require certain compromises. This research calls for various institutions and policymakers to work out solutions that enable all religious groups to work and live in harmony.Originality/valueTo the best of the authors’ knowledge, this research is the first to study religious compensatory consumption quantitatively. This research operationalized variables previously discussed using a qualitative approach, namely religious hypocrisy, social control, guilt and compensatory consumption. The authors designed and adapted their measurement scales to fit this context, paving the way for future research in this field. Second, this research provides new empirical evidence by examining the relationships among less explored variables. For instance, this research has proven that several aspects of religiosity (e.g. hypocrisy, social control and guilt) may influence compensatory consumption in the Islamic context. This research also reveals the mediation roles of religious social control and religious guilt that were less explored in the previous studies. To the best of their knowledge, previous studies had not addressed social control as a predictor of compensatory consumption. Therefore, the theoretical model presented in this research and the empirical findings extend the theory of compensatory consumption. Third, Muslims are underrepresented in the compensatory consumption research; therefore, this research fills the population gap. Finally, this research focuses on Islamic compensatory behaviour as the future direction of Islamic marketing. Previous Islamic marketing research had not addressed the sensitive motives of Islamic consumption, which have now been highlighted in this research.


2019 ◽  
Vol 18 (2) ◽  
pp. 110-117
Author(s):  
E. I Panova

The article presents results of analysis of concepts “health” and “disease” to identify patterns of changes in their meaning and content which resulted into increasing of technologization of modern medicine. Every of considered ways of interpreting concept of “disease” contains certain image of human and one's attitude to internal (natural) and external (natural, social) environment and determines the degree of necessity, direction and character of impact on human body. The modifications of ways these categories are interpreted reflect evolutionary transition of successive changes in three paradigms of medicine: biocentric - sociocentric - technocentric. There is no clear demarcation between pathological and normal states of organism in the biocentric paradigm. The medical standard is identical to biological one; its criterion is viability. In the sociocentric paradigm, social factors of human activity dominate natural ones. The concept of “disease” acquires negative meaning and begins to be defined as “failure”, violation of adaptation of human organism. The natural consequence of this approach is increasing of spectrum and intensity of medical intervention: medical technologies begin to be applied to eliminate biologically normal conditions of patient's body. The main feature of technocentric paradigm is its constructivist character: biomedicine seeks to create new states of human body and psyche that do not exist in the nature. Understanding health as “well-being” leads to relativity of medical standards that becomes depended on constantly changing individual standards.


2017 ◽  
Author(s):  
Geoffrey D Hannigan ◽  
Melissa B Duhaime ◽  
Danai Koutra ◽  
Patrick D Schloss

AbstractViruses and bacteria are critical components of the human microbiome and play important roles in health and disease. Most previous work has relied on studying bacteria and viruses independently, thereby reducing them to two separate communities. Such approaches are unable to capture how these microbial communities interact, such as through processes that maintain community robustness or allow phage-host populations to co-evolve. We implemented a network-based analytical approach to describe phage-bacteria network diversity throughout the human body. We built these community networks using a machine learning algorithm to predict which phages could infect which bacteria in a given microbiome. Our algorithm was applied to paired viral and bacterial metagenomic sequence sets from three previously published human cohorts. We organized the predicted interactions into networks that allowed us to evaluate phage-bacteria connectedness across the human body. We observed evidence that gut and skin network structures were person-specific and not conserved among cohabitating family members. High-fat diets appeared to be associated with less connected networks. Network structure differed between skin sites, with those exposed to the external environment being less connected and likely more susceptible to network degradation by microbial extinction events. This study quantified and contrasted the diversity of virome-microbiome networks across the human body and illustrated how environmental factors may influence phage-bacteria interactive dynamics. This work provides a baseline for future studies to better understand system perturbations, such as disease states, through ecological networks.Author SummaryThe human microbiome, the collection of microbial communities that colonize the human body, is a crucial component to health and disease. Two major components of the human microbiome are the bacterial and viral communities. These communities have primarily been studied separately using metrics of community composition and diversity. These approaches have failed to capture the complex dynamics of interacting bacteria and phage communities, which frequently share genetic information and work together to maintain ecosystem homestatsis (e.g. kill-the-winner dynamics). Removal of bacteria or phage can disrupt or even collapse those ecosystems. Relationship-based network approaches allow us to capture this interaction information. Using this network-based approach with three independent human cohorts, we were able to present an initial understanding of how phage-bacteria networks differ throughout the human body, so as to provide a baseline for future studies of how and why microbiome networks differ in disease states.


2010 ◽  
Vol 3 ◽  
Author(s):  
Diana Cárdenas ◽  
Dale Stout

The purpose of this study is to examine the relationship between intellectual abilities and personality in predicting intelligent behaviour, operationalized as good decision-making practices. This examination considers certain personal characteristics that are hypothesized to lead to intelligent behaviour, namely personality, emotional intelligence and subjective well-being. The study aims at understanding how such personal characteristics influence decision making. It was hypothesized that the relationship between intellectual abilities and decision making would be mediated or moderated by the personal characteristics mentioned previously. Ninety-seven participants took tests that assessed these factors. The analysis of the data revealed no significant correlation between intellectual abilities and decision making, nor was there a correlation between any of the personality factors and decision making or intelligence. It is suspected that the homogeneous sample did not allow for enough variance to show any correlation. Methodological corrections are suggested for future studies.


Sign in / Sign up

Export Citation Format

Share Document