scholarly journals The Relationship of Lifestyle Risk Factors and Depression in Korean Adults: A Moderating Effect of Overall Nutritional Adequacy

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2626
Author(s):  
Minjeong Kang ◽  
Mingyu Joo ◽  
Haeryun Hong ◽  
Hyunsik Kang

Background: Little is known regarding the role of nutrition in determining the associations between lifestyle risk factors and depression. Objectives: This study examined whether or not nutritional adequacy modulates the relationship between depression and lifestyle risk factors in Korean adults aged 18-65 years (n = 7446). Methods: Data were obtained from the 2016 and 2018 Korea National Health and Examination Survey. Depression, smoking, at-risk alcohol consumption, physical inactivity, sleep deprivation, and mean adequacy ratio (MAR) were assessed. Results: Individuals with two (OR = 1.960, p < 0.001), three (OR = 4.237, p < 0.001), or four (OR = 5.312, p < 0.001) risk factors had a significantly higher risk of depression compared to individuals with one or zero risk factor. In contrast, individuals with moderate MAR (OR = 0.607, p < 0.001) and high (OR = 0.698, p < 0.001) MAR had a lower depression risk compared to individuals with low MAR. Moderation analysis showed a moderating effect of MAR (coefficient = −0.220, p = 0.007) on the relationship between risk factors and depression. Conclusions: The current findings suggest that overall nutritional adequacy plays a modulating role in determining the relationship between depression and lifestyle risk factors in Korean adults.

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Shinuk Kim

Abstract Background Little is known regarding the role of gender as a possible modulator in determining the associations between lifestyle risk factors and depression in older adults. Objectives This study examined whether gender modulates the relationship between depression and lifestyle risk factors in Korean adults aged 65 years and older (n = 3700). Methods Data were obtained from the 2016 and 2018 Korea National Health and Examination Survey. The primary outcome was depression, assessed with the patient health questionnaire-9. As exposures, smoking habits, at-risk alcohol consumption, and physical inactivity were assessed with a standardized questionnaire. In addition, mean adequacy ratio (MAR) as an indicator of overall nutritional inadequacy was assessed with dietary intakes of macro- and micronutrients. Results In men only, either two or three and more risk factors were significantly associated with higher depression risk (OR (95% confidence interval, CI) = 2.886 (1.003–8.299) and OR (95% CI) = 3.109 (1.064–9.097), respectively). In women only, either two or three and more risk factors were also significantly associated with higher depression risk (OR (95% CI) = 1.505 (1.067–2.124) and OR (95% CI) = 2.828 (1.527–5.239), respectively). In particular, the presence of smoking habits and MAR were the major determinants of depression (OR (95% CI) = 1.835 (1.09–3.10) and OR (95% CI) = 1.585 (1.125–2.233), respectively) in women only. Finally, a moderation analysis with the Hayes PROCESS Macro showed a significant moderating effect of gender (β (95% CI) = 0.633 (0.206 ~ 1.060)) on the relationship between risk factors and depression. In addition, the slope of the relationship was much steeper in women than in men. Conclusion Current findings suggest that lifestyle risk factors are more closely associated with depression risk in women than in men.


2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Lucien McBeth ◽  
Maria Grabnar ◽  
Steven Selman ◽  
Terry D. Hinds

Bladder cancer is encountered worldwide having been associated with a host of environmental and lifestyle risk factors. The disease has a male to female prevalence of 3 : 1. This disparity has raised the possibility of the androgen receptor (AR) pathway being involved in the genesis of the disease; indeed, research has shown that AR is involved in and is likely a driver of bladder cancer. Similarly, an inflammatory response has been implicated as a major player in bladder carcinogenesis. Consistent with this concept, recent work on anti-inflammatory glucocorticoid signaling points to a pathway that may impact bladder cancer. The glucocorticoid receptor- (GR-)αisoform has an important role in suppressing inflammatory processes, which may be attenuated by AR in the development of bladder cancer. In addition, a GR isoform that is inhibitory to GRα, GRβ, is proinflammatory and has been shown to induce cancer growth. In this paper, we review the evidence of inflammatory mediators and the relationship of AR and GR isoforms as they relate to the propensity for bladder cancer.


2016 ◽  
Vol 48 ◽  
pp. 227
Author(s):  
YoungYun Jin ◽  
Sunghun Yang ◽  
Haeryon Hong ◽  
Changduk Ha ◽  
Jiyoung Kong ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Fang Gu ◽  
Siliang Zhou ◽  
Ke Lou ◽  
Rui Deng ◽  
Xingxiu Li ◽  
...  

Objectives: To assess the relationship between modifiable lifestyle factors and risk of overweight/obesity in Chinese students, and to evaluate the predicting prevalence of overweight if the lifestyle risk factors were removed.Methods: A cross-sectional survey was conducted among 40,141 students in grade three and above (8–24yrs) in 2019 in Zhejiang Province, China. Physical examination was performed, and a self-administered questionnaire was used to collect lifestyle information, including dietary behavior, physical activity, TV watching, sleeping, smoking, drinking, and tooth-brushing habits. Logistic regression models were performed to assess the relationship between overweight/obesity and a series of lifestyle factors. Population attributable fractions (PAFs) were used to calculate the predicting prevalence of overweight/obesity if lifestyle risk factors were removed.Results: The prevalence of overweight/obesity of participants was 25.5% (male 32.3%, female 18.1%). Overweight/obesity were associated with adverse lifestyle factors, such as watch TV ≥1 h/day (OR = 1.14, 95% CI: 1.11–1.22), insufficient sleep (OR = 1.14, 95% CI: 1.11–1.22), and irregular toothbrushing habits (OR = 1.19, 95% CI: 1.01–1.39). Based on the calculated PAFs, the predicted prevalence of overweight/obesity would decline moderately if lifestyle factors were modified, with the magnitudes of decrease vary by sex, age and residence. Generally, a larger reduction was estimated if the sleeping time was increased and TV time was reduced, with the prevalence of overweight/obesity decreased by 1.1% (95% CI: 0.7, 1.5%) and 0.9% (95% CI: 0.6, 1.2%), respectively.Conclusions: Predicted prevalence of overweight/ obesity in Chinese students may decrease if modifiable lifestyle risk factors were removed. The attributable risk for obesity of lifestyle behaviors varied in age, sex and residence groups. The findings of this study may provide insights for planning and optimizing future obesity intervention endeavors.


Author(s):  
J.A Prasansha Kumari ◽  
Dr. S.M. Ferdous Azam ◽  
Prof. Siti Khalidah

This article highlights the moderating effect of living areas of the borrowers on the impact of microfinance programs on poverty alleviation. The study has utilized the data from 497 borrowers of Samurdhi microfinance in five disaster-affected districts in the country to examines that two different living areas (disaster-affected and non-disaster affected area) of borrowers moderate the relationship between microfinance services and poverty alleviation. The Multi- Group CFA analysis was performed to identify the moderating effect using AMOS 21. Quantitative results were finding revealed that the moderation tests were significant for all the three microfinance services on poverty alleviation. The effect of microfinance services of borrowers in the disaster-affected area higher than the borrowers in non-disaster area.


Author(s):  
Mahesh K. Nalla ◽  
Yongjae Nam

This article examines the role of citizens’ contact with police and their assessments of officers’ corruption in police in India. More importantly, we examine whether police procedural justice moderates the relationship between citizens’ assessments of police corruption and trust. Data ( N = 845) from Delhi, India, suggest that consistent with the literature, citizens’ trust in police is explained by their contact with police, fear of crime, police effectiveness, and corruption in police work. However, two significant findings emerged from this analysis. First, though citizens’ perception of police corruption is a significant explanatory variable of trust in police, procedural justice moderates the strength of the relationship of corruption on trust. Second, the nature of contact experience reveals essential differences in the moderating effect of procedural justice on the relationship between corruption and trust in police. Finally, irrespective of the nature of contact experience, police effectiveness, and trust in police is related.


2021 ◽  
pp. 13-20
Author(s):  
Marian L. Fitzgibbon ◽  
Lisa Tussing-Humphreys ◽  
Angela Kong ◽  
Alexis Bains

Diet contributes to the development of 30% to 35% of cancers. Shifts in the food landscape have contributed to changes in dietary intake, energy balance, and the development of obesity. Obesity, defined as a body mass index (BMI) greater than or equal to 30 kg/m², is associated with several cancers. The World Cancer Research Fund (WCRF), the American Institute for Cancer Research (AICR), the American Cancer Society (ACS), and several large U.S.-based randomized trials are studying the relationship between diet, dietary patterns, lifestyle risk factors, obesity, and cancer. Prior research reported an association between individual nutrients and cancer risk. This research, however, did not fully investigate the complexity of diet and interactions between specific dietary components. Overall, according to data reported by the WCRF and the AICR, primary prevention of many cancers is possible through modifiable lifestyle changes. Identifying and intervening on barriers to lifestyle modifications remains a challenge, but it is increasingly apparent that there is a relationship between diet, lifestyle risk factors, and cancer development and that many cancers can be prevented.


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