scholarly journals Could Vitamin D3 Deficiency Influence Malocclusion Development?

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2122
Author(s):  
Anna Leszczyszyn ◽  
Sylwia Hnitecka ◽  
Marzena Dominiak
Keyword(s):  
Vitamin D3 ◽  
Venous Blood ◽  
Medical Interview ◽  
Radiological Imaging ◽  
Abnormal Growth ◽  
Skeletal Malocclusion ◽  
Skeletal Defect ◽  
The Impact ◽  
Vitamin D3 Deficiency ◽  
Common Defect

The abnormal growth of the craniofacial bone leads to skeletal and dental defects, which result in the presence of malocclusions. Not all causes of malocclusion have been explained. In the development of skeletal abnormalities, attention is paid to general deficiencies, including of vitamin D3 (VD3), which causes rickets. Its chronic deficiency may contribute to skeletal malocclusion. The aim of the study was to assess the impact of VD3 deficiency on the development of malocclusions. The examination consisted of a medical interview, oral examination, an alginate impression and radiological imaging, orthodontic assessment, and taking a venous blood sample for VD3 level testing. In about 42.1% of patients, the presence of a skeletal defect was found, and in 46.5% of patients, dentoalveolar malocclusion. The most common defect was transverse constriction of the maxilla with a narrow upper arch (30.7%). The concentration of vitamin 25 (OH) D in the study group was on average 23.6 ± 10.5 (ng/mL). VD3 deficiency was found in 86 subjects (75.4%). Our research showed that VD3 deficiency could be one of an important factor influencing maxillary development. Patients had a greater risk of a narrowed upper arch (OR = 4.94), crowding (OR = 4.94) and crossbite (OR = 6.16). Thus, there was a link between the deficiency of this hormone and the underdevelopment of the maxilla.

scholarly journals Influence of Vitamin D3 Deficiency on the Development of Malocclusions

2020 ◽  
Author(s):  
Anna Leszczyszyn ◽  
Marzena Dominiak ◽  
Sylwia Hnitecka
Keyword(s):  
Vitamin D ◽  
Vitamin D3 ◽  
Venous Blood ◽  
Skeletal Malocclusion ◽  
Skeletal Defect ◽  
Number Of Patients ◽  
Skeletal Defects ◽  
The Impact ◽  
The Relationship ◽  
Vitamin D3 Deficiency

Abstract Background: Insufficient or excessive growth of the craniofacial bone leads to skeletal and dental defects, which in turn result in the presence of malocclusions. To date, all causes of malocclusion have not been fully explained. In the development of skeletal abnormalities, attention is often paid to general deficiencies - including vitamin D3 deficiency, which causes rickets in growing people. It is suspected that its chronic deficiency may also affect the development of skeletal malocclusion. The aim of the study was to prospectively assess the impact of vitamin D deficiency on the development of malocclusions.Methods: The examination consisted of three parts - (1) medical interview, (2) orthodontic examination along with an alginate impression and radiological imaging, (3) taking a venous blood sample for vitamin D3 level testing.Results: In about 42,1% patients the presence of a skeletal defect was found. In 46,5% of patients presence of dentoalveolar malocclusion occurred. The most common skeletal defect was jaw narrowing in turn, among malocclusions most often retrogenia was diagnosed.Conclusions: A relatively small number of patients in the study group was diagnosed with skeletal malocclusion. Due to effects of vitamin D on the development and metabolism of bones, including jawbones, and the relationship with, for example, rickets, we believe that it would be worthwhile to conduct a study fully focused on the group of patients with skeletal defects.

scholarly journals The impact of vitamin D3 deficiency in the pathogenesis of non-alcoholic fatty liver disease

2020 ◽  
Vol 67 (S) ◽  
pp. 51-53
Author(s):  
Laura HUIBAN ◽  
◽  
Ana-Maria SÎNGEAP ◽  
Ştefan CHIRIAC ◽  
Anca TRIFAN ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Vitamin D3 ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
The Impact ◽  
Vitamin D3 Deficiency ◽  
Alcoholic Fatty Liver Disease

scholarly journals VITAMIN D3 DEFICIENCY;

2019 ◽  
Vol 26 (01) ◽  
Author(s):  
Suresh Kumar ◽  
Arshad ◽  
Bilawal Hingorjo ◽  
Nathumal Maheshwari ◽  
Rewachand ◽  
...  
Keyword(s):  
Serum Calcium ◽  
Vitamin D3 ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Total Study Population ◽  
Male And Female ◽  
Medical College ◽  
Vitamin D3 Deficiency ◽  
Apparently Healthy

Objectives: Determination of vitamin D3 deficiency and insufficiency in clinically asymptomatic and apparently healthy young adult male. Study Design: Cross sectional study. Study setting & Duration: Department of Medicine, Layari General Hospital Shaheed Muhtrama Benazir Bhutto Medical College from March 2015 to May 2016.Subjects and Methods: A sample of 100 volunteer participants, comprising of 57 male and female was selected according to the study criteria. 5 ml venous blood was collected in disposable syringe. Blood urea, serum creatinine, serum calcium and phosphate were estimated by standard laboratory procedures. ARCHITECT I 1000 system detected the vitamin D3. Data analysis was analysed by SPSS 22.0 (USA). Results: Serum Calcium and Phosphate were noted as 8.76±1.11 and 9.20±0.2 mg/dl (P=0.036) & 3.23±0.85 and 3.25±0.80 mg/dl (P=0.71) in male and female subjects respectively. Vitamin D3 (mean± SD) in male and female was noted as 23.0±8.24 and 27.19±14.13 ng/dl (P=0.006). Vitamin D3 (mean± SD) of total study population was noted as 24.80± 11.29 ng/ml. Frequency of vitamin D3 deficiency, insufficiency and sufficiency noted in 45%, 32% and 23% respectively (P=0.0001). Conclusion: We found vitamin D3 deficiency and insufficiency in 77% of young apparently healthy and clinically asymptomatic adults

The assessment of vitamin D3 deficiency in patients with Hashimoto's disease and the relationship between the disease duration and 25OHD3 levels

2018 ◽  
Author(s):  
Katarzyna Lizis-Kolus ◽  
Alicja Hubalewska-Dydejczyk ◽  
Anna Sowa-Staszczak ◽  
Anna Skalniak ◽  
Aldona Kowalska ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
Disease Duration ◽  
Hashimoto’S Disease ◽  
Hashimoto's Disease ◽  
The Relationship ◽  
Vitamin D3 Deficiency

Vitamin D3 Deficiency and COVID-19.

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Olen R. Brown ◽  
Martin R. Hullender
Keyword(s):  
Vitamin D3 ◽  
Vitamin D3 Deficiency

Effect of alkali therapy with NaHCO3 or THAM on cardiac contractility

1996 ◽  
Vol 270 (5) ◽  
pp. R955-R962
Author(s):  
C. D. Mazer ◽  
B. Naser ◽  
K. S. Kamel
Keyword(s):  
Myocardial Ischemia ◽  
Contractile Function ◽  
Venous Blood ◽  
Systolic Pressure ◽  
Ischemic Myocardium ◽  
Stroke Work ◽  
Length Relationship ◽  
Alkali Therapy ◽  
Myocardial Contractile ◽  
The Impact

We examined the impact of alkali therapy on myocardial contractility in a model of myocardial ischemia in dogs using direct measurements of myocardial contractile function. Myocardial ischemia in the left anterior descending (LAD) artery territory was induced using a perfusion circuit from the internal carotid artery to the LAD artery. Myocardial contractile function was assessed using sonomicrometry for measurement of percent systolic shortening (%SS), preload recruitable stroke work (PRSW) slope, and end-systolic pressure-length relationship (ESPLR) area. Because the blood flow in LAD artery was diminished by approximately 70%, there was a significant decrease in O2 delivery and uptake by the ischemic myocardium. Ischemia led to a significant fall in LAD regional contractile function with %SS decreasing from 15 +/- 2 to 7 +/- 2%, PRSW slope from 82 +/- 10 to 37 +/- 5 mmHg, and ESPLR area from 121 +/- 2 to 48 +/- 14 mmHg.mm (P < 0.05). In six dogs, the intracoronary administration of NaHCO(3) resulted in a significant increase in pH in LAD arterial and venous blood. There was, however, no significant increase in %SS (6 +/- 2), PRSW slope (43 +/- 10 mmHg), or ESPLR area (60 +/- 13 mmHg.mm). Since administration of NaHCO(3) resulted in a significant increase in PCO2 in LAD arterial and venous blood, similar experiments were carried out in five dogs, but with the intracoronary infusion of the amine buffer THAM [tris(hydroxymethyl)aminomethane (Tris) buffer; 2-amino-2-hydroxyl-1,3-propandiol] instead of NaHCO3. Although administration of THAM resulted in a significant increase in pH and a significant decrease in PCO2, in both LAD arterial and venous blood, there was no significant improvement in any of the parameters used to assess myocardial contractile function. In conclusion, administration of alkali (NaHCO3 or THAM) does not enhance the contractile function of the ischemic myocardium.

scholarly journals Prevalence of SARS-CoV-2 Infection at the University of Barcelona during the Third COVID-19 Pandemic Wave in Spain

2021 ◽  
Vol 18 (12) ◽  
pp. 6526
Author(s):  
Sebastián Videla ◽  
Aurema Otero ◽  
Sara Martí ◽  
M. Ángeles Domínguez ◽  
Nuria Fabrellas ◽  
...  
Keyword(s):  
Ad Hoc ◽  
Venous Blood ◽  
Herd Immunity ◽  
Cross Sectional Study ◽  
Rt Pcr ◽  
Igg Antibody ◽  
Cross Sectional ◽  
Total Prevalence ◽  
The University ◽  
The Impact

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic started in December 2019 and still is a major global health challenge. Lockdown measures and social distancing sparked a global shift towards online learning, which deeply impacted universities’ daily life, and the University of Barcelona (UB) was not an exception. Accordingly, we aimed to determine the impact of the SARS-CoV-2 pandemic at the UB. To that end, we performed a cross-sectional study on a sample of 2784 UB members (n = 52,529). Participants answered a brief, ad hoc, online epidemiological questionnaire and provided a nasal swab for reverse transcription polymerase chain reaction (RT-PCR) SARS-CoV-2 analysis and a venous blood sample for SARS-CoV-2 IgG antibody assay. Total prevalence of SARS-CoV-2 infection (positive RT-PCR or positive IgG) was 14.9% (95%CI 13.3 to 17.0%). Forty-four participants (1.6%, 95%CI: 1.2–2.1%) were positive for SARS-CoV-2 RT-PCR. IgG against SARS-CoV-2 was observed in 12.8% (95%CI: 11.6–14.1%) of participants. Overall, while waiting for population vaccination and/or increased herd immunity, we should concentrate on identifying and isolating new cases and their contacts.

scholarly journals Effect of Whole-Body Cryotherapy on Morphological, Rheological and Biochemical Indices of Blood in People with Multiple Sclerosis

2021 ◽  
Vol 10 (13) ◽  
pp. 2833
Author(s):  
Bartłomiej Ptaszek ◽  
Aneta Teległów ◽  
Justyna Adamiak ◽  
Jacek Głodzik ◽  
Szymon Podsiadło ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Neurological Diseases ◽  
Venous Blood ◽  
Whole Body ◽  
Controlled Study ◽  
Control Group ◽  
Blood Indices ◽  
Rheological Indices ◽  
Whole Body Cryotherapy ◽  
The Impact

The aim of this study was to examine and assess the impact of a series of 20 whole-body cryotherapy (WBC) treatments on the biochemical and rheological indices of blood in people with multiple sclerosis. In this prospective controlled study, the experimental group consisted of 15 women aged 34–55 (mean age, 41.53 ± 6.98 years) with diagnosed multiple sclerosis who underwent a series of whole-body cryotherapy treatments. The first control group consisted of 20 women with diagnosed multiple sclerosis. This group had no intervention in the form of whole-body cryotherapy. The second control group consisted of 15 women aged 30–49 years (mean age, 38.47 ± 6.0 years) without neurological diseases and other chronic diseases who also underwent the whole-body cryotherapy treatment. For the analysis of the blood indices, venous blood was taken twice (first, on the day of initiation of whole-body cryotherapy treatments and, second, after a series of 20 cryotherapy treatments). The blood counts were determined using an ABX MICROS 60 hematological analyzer (USA). The LORCA analyzer (Laser–Optical Rotational Cell Analyzer, RR Mechatronics, the Netherlands) was used to study the aggregation and deformability of erythrocytes. The total protein serum measurement was performed using a Cobas 6000 analyzer, Roche and a Proteinogram-Minicap Sebia analyzer. Fibrinogen determinations were made using a Bio-Ksel, Chrom-7 camera. Statistically significant differences and changes after WBC in the levels of red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), elongation index, total extend of aggregation (AMP), and proteins (including fibrinogen) were observed. However, there was no significant effect of a series of 20 WBC treatments on changes in blood counts, rheology, and biochemistry in women with multiple sclerosis. Our results show that the use of WBC has a positive effect on the rheological properties of the blood of healthy women.

scholarly journals A Quantitative Point-of-Need Assay for the Assessment of Vitamin D3 Deficiency

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
S. Vemulapati ◽  
E. Rey ◽  
D. O’Dell ◽  
S. Mehta ◽  
D. Erickson
Keyword(s):  
Vitamin D3 ◽  
Vitamin D3 Deficiency
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